The network for 'dorsal ventral pattern formation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

dorsal ventral pattern formation

The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.

Drosophila melanogaster
Name Description Probability Func Analog Organism
shn schnurri 0.989
ci cubitus interruptus 0.976
fz2 frizzled 2 0.973
Egfr Epidermal growth factor receptor 0.967
Hrb27C Heterogeneous nuclear ribonucleoprotein at 27C 0.963
milt milton 0.941
Dad Daughters against dpp 0.939
eya eyes absent 0.901
wg wingless 0.900
slmb supernumerary limbs 0.893
spen split ends 0.892
tsh teashirt 0.889
HLHm7 E(spl) region transcript m7 0.850
Src64B Src oncogene at 64B 0.849
N Notch 0.838
mam mastermind 0.818
slp1 sloppy paired 1 0.816
Dl Delta 0.798
nkd naked cuticle 0.789
emc extra macrochaetae 0.788
tup tailup 0.784
spn-B spindle B 0.765
brat brain tumor 0.764
mael maelstrom 0.736
sqd squid 0.712
HLHmbeta E(spl) region transcript mbeta 0.704
wls wntless 0.699
sog short gastrulation 0.695
Trl Trithorax-like 0.681
phl pole hole 0.680
Tl Toll 0.671
sd scalloped 0.653
Cul-3 Cullin-3 0.630
hth homothorax 0.616
tefu telomere fusion 0.605
ovo CG6824 gene product from transcript CG6824-RE 0.582
hh hedgehog 0.574
ftz-f1 ftz transcription factor 1 0.562
E(spl) Enhancer of split 0.561
nuf nuclear fallout 0.549
dx deltex 0.546
nub nubbin 0.532
dpp decapentaplegic 0.525
osk oskar 0.507
sc scute 0.505
BicD Bicaudal D 0.479
brk brinker 0.477
sbb scribbler 0.468
csw corkscrew 0.455
Imp IGF-II mRNA-binding protein 0.453
fng fringe 0.449
InR Insulin-like receptor 0.449
Sin3A CG8815 gene product from transcript CG8815-RC 0.448
sktl skittles 0.448
18w 18 wheeler 0.430
Kr-h1 Kruppel homolog 1 0.430
kni knirps 0.423
Wnt4 Wnt oncogene analog 4 0.421
pum pumilio 0.418
fz frizzled 0.414
bab2 CG9102 gene product from transcript CG9102-RA 0.404
babo baboon 0.399
HLHmgamma E(spl) region transcript mgamma 0.395
CG12424 CG12424 gene product from transcript CG12424-RC 0.392
ss spineless 0.373
zfh2 Zn finger homeodomain 2 0.372
CycG Cyclin G 0.370
bai baiser 0.367
gbb glass bottom boat 0.365
vvl ventral veins lacking 0.361
tsl torso-like 0.358
Notum CG13076 gene product from transcript CG13076-RB 0.351
Smox Smad on X 0.347
nej nejire 0.342
pnr pannier 0.339
Antp Antennapedia 0.337
mtrm matrimony 0.334
spn-F CG12114 gene product from transcript CG12114-RA 0.332
Brca2 Breast cancer 2, early onset homolog 0.328
tll tailless 0.320
grn grain 0.315
sax saxophone 0.313
zuc zucchini 0.311
dally division abnormally delayed 0.311
Rae1 CG9862 gene product from transcript CG9862-RA 0.306
osa CG7467 gene product from transcript CG7467-RD 0.306
vas vasa 0.305
CSN8 COP9 complex homolog subunit 8 0.300
hipk homeodomain interacting protein kinase 0.296
stau staufen 0.293
Snoo Sno oncogene 0.292
Ubx Ultrabithorax 0.291
amos absent MD neurons and olfactory sensilla 0.285
Myd88 CG2078 gene product from transcript CG2078-RA 0.280
otk off-track 0.279
ksr kinase suppressor of ras 0.277
TER94 CG2331 gene product from transcript CG2331-RA 0.277
ac achaete 0.274
usp ultraspiracle 0.271
Klp64D Kinesin-like protein at 64D 0.271
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
chd chordin 0.996
fgf3 fibroblast growth factor 3 0.993
wnt11 wingless-type MMTV integration site family, member 11 0.983
flh floating head 0.982
dkk1b dickkopf 1b 0.982
ndr2 nodal-related 2 0.975
tbx16 T-box gene 16 0.975
ntla no tail a 0.968
bmp2b bone morphogenetic protein 2b 0.961
wnt5b wingless-type MMTV integration site family, member 5b 0.941
lef1 lymphocyte enhancer binding factor 1 0.929
hoxd4a homeo box D4a 0.914
fras1 Fraser syndrome 1 0.875
admp anti-dorsalizing morphogenic protein 0.865
ephb4b eph receptor B4b 0.823
gbx2 gastrulation brain homeo box 2 0.816
snai1b snail homolog 1b (Drosophila) 0.810
sp8a sp8 transcription factor a 0.799
fgfr1a fibroblast growth factor receptor 1a 0.774
mos v-mos Moloney murine sarcoma viral oncogene homolog 0.773
bmp4 bone morphogenetic protein 4 0.768
dlx2a distal-less homeobox gene 2a 0.767
il17rd interleukin 17 receptor D 0.763
col2a1a collagen type II, alpha-1a 0.749
gli1 GLI-Kruppel family member 1 0.743
sox32 SRY-box containing gene 32 0.742
six4b sine oculis homeobox homolog 4b 0.739
sox17 SRY-box containing gene 17 0.738
twist3 twist3 0.735
cxcr4b chemokine (C-X-C motif), receptor 4b 0.731
cdx4 caudal type homeo box transcription factor 4 0.730
foxg1a forkhead box G1a 0.728
snai1a snail homolog 1a (Drosophila) 0.726
spry4 sprouty (Drosophila) homolog 4 0.698
vent ventral expressed homeobox 0.697
eomesa eomesodermin homolog a 0.696
wnt4a wingless-type MMTV integration site family, member 4a 0.677
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.676
sox3 SRY-box containing gene 3 0.676
msxe muscle segment homeobox E 0.674
wnt9b wingless-type MMTV integration site family, member 9B 0.672
cdkn1c cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.671
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.668
dusp6 dual specificity phosphatase 6 0.663
msxd muscle segment homeobox D 0.613
jag2 jagged 2 0.612
dlx5a distal-less homeobox gene 5a 0.597
olfm2 olfactomedin 2 0.595
gata3 GATA-binding protein 3 0.579
eya1 eyes absent homolog 1 0.578
bmp7a bone morphogenetic protein 7a 0.577
tll1 tolloid-like 1 0.576
fzd5 frizzled homolog 5 0.568
bmp2a bone morphogenetic protein 2a 0.562
hoxb2a homeo box B2a 0.553
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.550
lft1 lefty1 0.544
zic2a zic family member 2 (odd-paired homolog, Drosophila), a 0.543
scinla scinderin like a 0.535
sox1a SRY-box containing gene 1a 0.531
mib mind bomb 0.526
lhx1b LIM homeobox 1b 0.519
zeb1 zinc finger E-box binding homeobox 1 0.513
btg2 B-cell translocation gene 2 0.513
lhx3 LIM homeobox 3 0.500
ascl1a achaete-scute complex-like 1a (Drosophila) 0.496
ihha Indian hedgehog homolog a 0.496
fzd8b frizzled homolog 8b 0.495
zic4 zic family member 4 0.478
tardbp TAR DNA binding protein 0.466
cxcl12b chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1) 0.463
mmp15b matrix metallopeptidase 15b 0.449
boc brother of CDO 0.441
cxcr4a chemokine (C-X-C motif) receptor 4a 0.435
dla deltaA 0.431
her5 hairy-related 5 0.428
dharma dharma 0.427
brd4 bromodomain containing 4 0.427
chrna2a cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal) 0.427
wnt7ba wingless-type MMTV integration site family, member 7Ba 0.420
acvr1l activin A receptor, type I like 0.417
hmx1 H6 homeo box 1 0.413
notch1a notch homolog 1a 0.407
jag1b jagged 1b 0.406
fgfr1b fibroblast growth factor receptor 1b 0.405
nkx6.1 NK6 transcription factor related, locus 1 (Drosophila) 0.402
fzd7a frizzled homolog 7a 0.402
dazl daz-like gene 0.401
emx3 empty spiracles homeobox 3 0.400
wnt11r wingless-type MMTV integration site family, member 11, related 0.394
cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.393
dlc deltaC 0.392
wnt10a wingless-type MMTV integration site family, member 10a 0.388
gpc4 glypican 4 0.387
chrna4 cholinergic receptor, nicotinic, alpha 4 0.379
sox19a SRY-box containing gene 19a 0.379
midn midnolin 0.377
zic1 zic family member 1 (odd-paired homolog, Drosophila) 0.377
wnt8b wingless-type MMTV integration site family, member 8b 0.373
bmpr1aa bone morphogenetic protein receptor, type 1aa 0.371
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Homo sapiens
Name Description Probability Func Analog Organism
SMAD3 SMAD family member 3 0.999
SMAD2 SMAD family member 2 0.997
SMAD1 SMAD family member 1 0.900
BMPR1A bone morphogenetic protein receptor, type IA 0.694
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.619
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.441
RBL2 retinoblastoma-like 2 (p130) 0.434
BMP2 bone morphogenetic protein 2 0.368
PSEN1 presenilin 1 0.367
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.342
SKI v-ski sarcoma viral oncogene homolog (avian) 0.324
TADA3 transcriptional adaptor 3 0.306
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.302
TGFB1 transforming growth factor, beta 1 0.300
FSTL1 follistatin-like 1 0.261
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.199
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.195
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.180
FKBP1A FK506 binding protein 1A, 12kDa 0.155
TGFBR1 transforming growth factor, beta receptor 1 0.151
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.147
MAFG v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) 0.143
TWIST1 twist homolog 1 (Drosophila) 0.130
ACVR1 activin A receptor, type I 0.125
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.123
KEAP1 kelch-like ECH-associated protein 1 0.122
NOTCH3 notch 3 0.121
CHRD chordin 0.112
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.108
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 0.105
APC adenomatous polyposis coli 0.103
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.102
NOTCH1 notch 1 0.100
JAG1 jagged 1 0.094
AR androgen receptor 0.094
C19orf39 chromosome 19 open reading frame 39 0.093
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.092
DAB2 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) 0.092
CSNK2B casein kinase 2, beta polypeptide 0.090
BMP7 bone morphogenetic protein 7 0.089
SMAD7 SMAD family member 7 0.085
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.080
WNT3A wingless-type MMTV integration site family, member 3A 0.079
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.078
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.074
QKI quaking homolog, KH domain RNA binding (mouse) 0.074
ERBB2IP erbb2 interacting protein 0.073
RANBP9 RAN binding protein 9 0.069
DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 0.065
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.062
PAX8 paired box 8 0.061
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.061
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.057
SKIL SKI-like oncogene 0.056
SMAD4 SMAD family member 4 0.050
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.047
GSK3B glycogen synthase kinase 3 beta 0.046
FOXA2 forkhead box A2 0.045
AKAP11 A kinase (PRKA) anchor protein 11 0.045
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.044
PTCH1 patched 1 0.044
PCBP1 poly(rC) binding protein 1 0.044
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.043
BMP4 bone morphogenetic protein 4 0.042
COL2A1 collagen, type II, alpha 1 0.041
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.040
HOXB5 homeobox B5 0.040
IRAK1 interleukin-1 receptor-associated kinase 1 0.040
MAPK8 mitogen-activated protein kinase 8 0.040
RBMX RNA binding motif protein, X-linked 0.040
PML promyelocytic leukemia 0.039
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.037
NLK nemo-like kinase 0.037
YBX1 Y box binding protein 1 0.036
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.035
NOTCH2 notch 2 0.035
ZFYVE9 zinc finger, FYVE domain containing 9 0.034
CAV2 caveolin 2 0.034
RAD51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.034
MYOD1 myogenic differentiation 1 0.032
HOXC8 homeobox C8 0.031
MAPK6 mitogen-activated protein kinase 6 0.031
EIF3A eukaryotic translation initiation factor 3, subunit A 0.030
NOG noggin 0.029
AXIN1 axin 1 0.029
ATF2 activating transcription factor 2 0.029
LRP6 low density lipoprotein receptor-related protein 6 0.028
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.028
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 0.028
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 0.028
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.028
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.027
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.027
FZD7 frizzled homolog 7 (Drosophila) 0.027
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.026
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.026
EGFR epidermal growth factor receptor 0.026
FLNB filamin B, beta 0.026
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.025
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.024
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Rps26 ribosomal protein S26 0.016
Rps21 ribosomal protein S21 0.015
Rpl11 ribosomal protein L11 0.014
Rpl23a ribosomal protein L23a 0.014
Rpl19 ribosomal protein L19 0.014
Rpl15 ribosomal protein L15 0.014
Rpl10a ribosomal protein L10A 0.014
Ssr4 signal sequence receptor, delta 0.014
Rpl5 ribosomal protein L5 0.013
Rpl8 ribosomal protein L8 0.013
Rpl23 ribosomal protein L23 0.013
Rpl27 ribosomal protein L27 0.013
Rps11 ribosomal protein S11 0.013
LOC100362298 ribosomal protein S18-like 0.013
Rpsa ribosomal protein SA 0.013
Rps5 ribosomal protein S5 0.013
Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.013
Rps28 ribosomal protein S28 0.013
LOC100359498 ribosomal protein L35a-like 0.013
Rps10 ribosomal protein S10 0.012
Rpl18a ribosomal protein L18A 0.012
LOC301124 hypothetical LOC301124 0.012
Rpl31 ribosomal protein L31 0.012
Rps15 ribosomal protein S15 0.012
Rpl29 ribosomal protein L29 0.012
Gnb2l1 guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 0.012
Eif3m eukaryotic translation initiation factor 3, subunit M 0.012
Rps9 ribosomal protein S9 0.012
Fau Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.012
Rpl26 ribosomal protein L26 0.012
Rpl34 ribosomal protein L34 0.012
Rpl36a ribosomal protein L36a 0.012
Rpl37 ribosomal protein L37 0.012
Rplp0 ribosomal protein, large, P0 0.012
Rps15a ribosomal protein S15a 0.012
Rps27a ribosomal protein S27a 0.012
Rpl35 ribosomal protein L35 0.012
Etfa electron-transfer-flavoprotein, alpha polypeptide 0.012
Cops5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) 0.012
Rpl6 ribosomal protein L6 0.012
Rps3 ribosomal protein S3 0.012
Rpl14 ribosomal protein L14 0.012
Rps6 ribosomal protein S6 0.012
Ostc oligosaccharyltransferase complex subunit 0.012
Rps19 ribosomal protein S19 0.012
Psmb1 proteasome (prosome, macropain) subunit, beta type 1 0.012
Ict1 immature colon carcinoma transcript 1 0.012
Rac2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.011
Ndufc2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2 0.011
Rpl3 ribosomal protein L3 0.011
Snrpd2 small nuclear ribonucleoprotein D2 polypeptide 0.011
Rps14 ribosomal protein S14 0.011
Rps8 ribosomal protein S8 0.011
Rpl36al ribosomal protein L36a-like 0.011
Rpl10 ribosomal protein L10 0.011
Naca nascent polypeptide-associated complex alpha subunit 0.011
Rps2 ribosomal protein S2 0.011
Sec61b Sec61 beta subunit 0.011
Rps17 ribosomal protein S17 0.011
Rps25 ribosomal protein s25 0.011
Rps4x ribosomal protein S4, X-linked 0.011
Sfrs11 splicing factor, arginine/serine-rich 11 0.011
Eif3i eukaryotic translation initiation factor 3, subunit I 0.011
Rpl41 ribosomal protein L41 0.011
Chmp2a chromatin modifying protein 2A 0.011
Aprt adenine phosphoribosyl transferase 0.011
Ndufb6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6 0.011
RGD1564058 similar to cDNA sequence BC056474 0.011
Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 0.011
Mettl5 methyltransferase like 5 0.011
Rpl4 ribosomal protein L4 0.011
LOC499782 similar to 60S ribosomal protein L12 0.011
LOC100188932 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 0.011
Tmem126a transmembrane protein 126A 0.011
Rpl21 ribosomal protein L21 0.011
Rpl27a ribosomal protein L27a 0.011
Coq3 coenzyme Q3 homolog, methyltransferase (S. cerevisiae) 0.011
Rpl38 ribosomal protein L38 0.011
Eif3g eukaryotic translation initiation factor 3, subunit G 0.011
Phb prohibitin 0.011
Tyrobp Tyro protein tyrosine kinase binding protein 0.011
Ap2m1 adaptor-related protein complex 2, mu 1 subunit 0.011
Tagln2 transgelin 2 0.011
Bet1 blocked early in transport 1 homolog (S. cerevisiae) 0.011
Tmco1 transmembrane and coiled-coil domains 1 0.011
Pcm1 pericentriolar material 1 0.011
Tceb2 transcription elongation factor B (SIII), polypeptide 2 0.011
Eef1d eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.011
Nae1 NEDD8 activating enzyme E1 subunit 1 0.011
LOC687029 similar to differentially expressed in B16F10 1 0.011
Rpl24 ribosomal protein L24 0.011
Myl6l myosin, light polypeptide 6, alkali, smooth muscle and non-muscle-like 0.011
Btf3 basic transcription factor 3 0.011
Rps7 ribosomal protein S7 0.011
Psmb4 proteasome (prosome, macropain) subunit, beta type 4 0.011
Bcl2a1d B-cell leukemia/lymphoma 2 related protein A1d 0.011
Mrpl27 mitochondrial ribosomal protein L27 0.011
LOC100360491 60S ribosomal protein L13-like 0.011
Ssbp1 single-stranded DNA binding protein 1 0.011
Rps23 ribosomal protein S23 0.011
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism