The network for 'immune system process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

immune system process

Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

Drosophila melanogaster
Name Description Probability Func Analog Organism
N Notch 1.000
PGRP-LC Peptidoglycan recognition protein LC 0.999
Tl Toll 0.999
Rel Relish 0.999
Egfr Epidermal growth factor receptor 0.997
hep hemipterous 0.996
rl rolled 0.995
Dredd Death related ced-3/Nedd2-like protein 0.995
wg wingless 0.995
key kenny 0.992
AttA Attacin-A 0.990
dom domino 0.989
ecd ecdysoneless 0.988
Pli Pellino 0.988
grass Gram-positive Specific Serine protease 0.987
BG4 CG12297 gene product from transcript CG12297-RA 0.985
Lis-1 Lissencephaly-1 0.985
dia diaphanous 0.985
dpp decapentaplegic 0.983
SPE Spatzle-Processing Enzyme 0.980
Myd88 CG2078 gene product from transcript CG2078-RA 0.980
Rac1 CG2248 gene product from transcript CG2248-RA 0.980
drk downstream of receptor kinase 0.977
Cdc42 CG12530 gene product from transcript CG12530-RA 0.976
Akt1 CG4006 gene product from transcript CG4006-RA 0.975
Dcr-2 Dicer-2 0.972
Ser Serrate 0.968
krz kurtz 0.964
Pvr PDGF- and VEGF-receptor related 0.964
AGO2 Argonaute 2 0.962
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.959
ap apterous 0.957
Atg1 Autophagy-specific gene 1 0.950
babo baboon 0.950
Sp7 Serine protease 7 0.948
PGRP-SA Peptidoglycan recognition protein SA 0.946
Mpk2 CG5475 gene product from transcript CG5475-RB 0.946
dco discs overgrown 0.944
Pp2B-14D Protein phosphatase 2B at 14D 0.944
Rac2 CG8556 gene product from transcript CG8556-RA 0.943
fon fondue 0.942
spz spatzle 0.942
Spn27A Serpin 27A 0.936
Dhc64C Dynein heavy chain 64C 0.929
sno strawberry notch 0.929
aop anterior open 0.928
cact cactus 0.926
ik2 IkappaB kinase-like 2 0.923
ird5 immune response deficient 5 0.918
Src42A Src oncogene at 42A 0.915
lwr lesswright 0.906
norpA no receptor potential A 0.906
shn schnurri 0.905
Glt Glutactin 0.905
bs blistered 0.903
ird1 immune response deficient 1 0.894
Fmr1 CG6203 gene product from transcript CG6203-RC 0.893
G-oalpha47A G protein oalpha 47A 0.889
Cat Catalase 0.886
imd immune deficiency 0.885
CG11376 CG11376 gene product from transcript CG11376-RA 0.882
ci cubitus interruptus 0.878
slmb supernumerary limbs 0.875
bsk basket 0.874
shot short stop 0.870
CG32185 CG32185 gene product from transcript CG32185-RA 0.867
l(2)gl lethal (2) giant larvae 0.866
Tab2 TAK1-associated binding protein 2 0.865
foxo forkhead box, sub-group O 0.859
da daughterless 0.854
luna CG33473 gene product from transcript CG33473-RB 0.854
put punt 0.850
Irc Immune-regulated catalase 0.849
jar jaguar 0.847
trol terribly reduced optic lobes 0.846
rpr reaper 0.843
DptB Diptericin B 0.835
proPO-A1 prophenol oxidase A1 0.834
Hsf Heat shock factor 0.833
Shc SHC-adaptor protein 0.832
mys myospheroid 0.831
GNBP3 Gram-negative bacteria binding protein 3 0.830
E(spl) Enhancer of split 0.830
PGRP-SD CG7496 gene product from transcript CG7496-RA 0.826
os outstretched 0.811
klu klumpfuss 0.810
LanA Laminin A 0.809
l(3)mbn lethal (3) malignant blood neoplasm 0.805
Alk CG8250 gene product from transcript CG8250-RA 0.799
HLHm7 E(spl) region transcript m7 0.799
scny scrawny 0.795
Pten CG5671 gene product from transcript CG5671-RB 0.790
mib1 mind bomb 1 0.787
Snr1 Snf5-related 1 0.786
rin rasputin 0.785
S6k RPS6-p70-protein kinase 0.781
ush u-shaped 0.780
eater CG6124 gene product from transcript CG6124-RB 0.779
kn knot 0.775
egh egghead 0.768
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
bmp2b bone morphogenetic protein 2b 0.993
kdrl kinase insert domain receptor like 0.978
runx1 runt-related transcription factor 1 0.976
tpm4 tropomyosin 4 0.966
pea3 ETS-domain transcription factor pea3 0.962
LOC566708 FL cytokine receptor-like 0.955
wnt10a wingless-type MMTV integration site family, member 10a 0.937
spns2 spinster homolog 2 (Drosophila) 0.937
shha sonic hedgehog a 0.903
ikzf1 IKAROS family zinc finger 1 (Ikaros) 0.901
mpx myeloid-specific peroxidase 0.883
tbx16 T-box gene 16 0.881
neo1 neogenin 1 0.872
rhogb ras homolog gene family, member Gb 0.870
tie1 endothelium-specific receptor tyrosine kinase 1 0.870
cmyb transcription factor cmyb 0.863
hbbe1.1 hemoglobin beta embryonic-1.1 0.857
edn1 endothelin 1 0.850
erg v-ets erythroblastosis virus E26 oncogene like (avian) 0.845
tp53 tumor protein p53 0.830
plcg1 phospholipase C, gamma 1 0.830
sema3aa semaphorin 3aa 0.828
hoxb2a homeo box B2a 0.825
dlc deltaC 0.816
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.809
mych myelocytomatosis oncogene homolog 0.809
rpl23a ribosomal protein L23a 0.805
pkd2 polycystic kidney disease 2 0.801
tal1 T-cell acute lymphocytic leukemia 1 0.793
ptprc protein tyrosine phosphatase, receptor type, C 0.793
gdnf glial cell derived neurotrophic factor 0.788
mll myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.780
pycard PYD and CARD domain containing 0.778
alas2 aminolevulinate, delta-, synthetase 2 0.777
slc4a1a solute carrier family 4, anion exchanger, member 1a 0.775
pcna proliferating cell nuclear antigen 0.763
lyz lysozyme 0.760
wasb Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b 0.751
fzd10 frizzled homolog 10 0.751
dld deltaD 0.747
spi1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 0.741
efnb2a ephrin B2a 0.731
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.724
tp63 tumor protein p63 0.724
per3 period homolog 3 (Drosophila) 0.720
rab11fip4a RAB11 family interacting protein 4 (class II) a 0.720
krml2.2 Kreisler (mouse) maf-related leucine zipper homolog 2.2 0.712
mstnb myostatin b 0.711
sfrp1a secreted frizzled-related protein 1a 0.709
aplnrb apelin receptor b 0.707
pitx2 paired-like homeodomain transcription factor 2 0.705
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.703
rarga retinoic acid receptor gamma a 0.701
gata1a GATA binding protein 1a 0.692
runx2a runt-related transcription factor 2a 0.681
dlb deltaB 0.680
cdh5 cadherin 5 0.673
epb41 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) 0.673
eomesa eomesodermin homolog a 0.668
tfr1a transferrin receptor 1a 0.664
osr1 odd-skipped related 1 (Drosophila) 0.662
s1pr2 sphingosine-1-phosphate receptor 2 0.658
tgfb3 transforming growth factor, beta 3 0.657
chd chordin 0.641
hnf1ba HNF1 homeobox Ba 0.638
gata3 GATA-binding protein 3 0.637
met met proto-oncogene (hepatocyte growth factor receptor) 0.630
runx2b runt-related transcription factor 2b 0.630
hoxb3a homeo box B3a 0.627
grem2 gremlin 2, cysteine knot superfamily 0.620
dkk1b dickkopf 1b 0.619
wt1a wilms tumor 1a 0.618
mtmr8 myotubularin related protein 8 0.616
fgf8a fibroblast growth factor 8 a 0.611
socs1 suppressor of cytokine signaling 1 0.610
twist1a twist1a 0.610
acvr1l activin A receptor, type I like 0.609
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.603
socs3a suppressor of cytokine signaling 3a 0.601
hhip hedgehog interacting protein 0.601
wnt11r wingless-type MMTV integration site family, member 11, related 0.600
gh1 growth hormone 1 0.595
junb jun B proto-oncogene 0.594
LOC100151531 zinc finger protein Gfi-1b-like 0.594
osr2 odd-skipped related 2 (Drosophila) 0.591
wt1b wilms tumor 1b 0.591
myd88 myeloid differentiation primary response gene (88) 0.590
nfe2 nuclear factor, erythroid-derived 2 0.588
hand2 heart and neural crest derivatives expressed transcript 2 0.586
npm1 nucleophosmin 1 0.585
znfl2a zinc finger-like gene 2a 0.583
sox2 SRY-box containing gene 2 0.580
tlr3 toll-like receptor 3 0.574
vegfc vascular endothelial growth factor c 0.570
ptprk protein tyrosine phosphatase, receptor type, K 0.569
cdx4 caudal type homeo box transcription factor 4 0.566
rag1 recombination activating gene 1 0.565
kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 0.564
ldb2a LIM-domain binding factor 2a 0.559
hoxa1a homeo box A1a 0.556
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
RT1-Da RT1 class II, locus Da 0.963
Hck hemopoietic cell kinase 0.951
Cd53 Cd53 molecule 0.917
Ccr5 chemokine (C-C motif) receptor 5 0.911
RT1-Ba RT1 class II, locus Ba 0.903
Ptafr platelet-activating factor receptor 0.881
Ptprc protein tyrosine phosphatase, receptor type, C 0.858
Cd74 Cd74 molecule, major histocompatibility complex, class II invariant chain 0.853
Lyz2 lysozyme 2 0.840
RT1-Db1 RT1 class II, locus Db1 0.827
Casp1 caspase 1 0.823
Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.800
Plek pleckstrin 0.794
Prf1 perforin 1 (pore forming protein) 0.779
Cd37 CD37 molecule 0.761
Fcgr2a Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.757
Cp ceruloplasmin 0.749
Il1b interleukin 1 beta 0.736
Il8rb interleukin 8 receptor, beta 0.728
Lcp1 lymphocyte cytosolic protein 1 0.719
Mmp12 matrix metallopeptidase 12 0.718
Ccl4 chemokine (C-C motif) ligand 4 0.696
Fcnb ficolin B 0.687
Sell selectin L 0.680
Cpb2 carboxypeptidase B2 (plasma) 0.669
Phkg1 phosphorylase kinase, gamma 1 0.669
Cd68 Cd68 molecule 0.666
Klf6 Kruppel-like factor 6 0.660
C5ar1 complement component 5a receptor 1 0.659
P2ry14 purinergic receptor P2Y, G-protein coupled, 14 0.657
Inpp5d inositol polyphosphate-5-phosphatase D 0.654
Ly86 lymphocyte antigen 86 0.652
Cd44 Cd44 molecule 0.646
Stat3 signal transducer and activator of transcription 3 0.646
Slc16a8 solute carrier family 16, member 8 (monocarboxylic acid transporter 3) 0.625
Ampd1 adenosine monophosphate deaminase 1 (isoform M) 0.616
Ctss cathepsin S 0.616
Cd247 Cd247 molecule 0.612
Ccr2 chemokine (C-C motif) receptor 2 0.608
Cxcl2 chemokine (C-X-C motif) ligand 2 0.607
Cxcr3 chemokine (C-X-C motif) receptor 3 0.605
Prrx1 paired related homeobox 1 0.602
Adora2a adenosine A2a receptor 0.594
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.584
Vcam1 vascular cell adhesion molecule 1 0.579
Ncf1 neutrophil cytosolic factor 1 0.575
Gpnmb glycoprotein (transmembrane) nmb 0.573
Prl8a7 prolactin family 8, subfamily a, member 7 0.570
Actb actin, beta 0.564
Neurl3 neuralized homolog 3 (Drosophila) 0.559
Cd4 Cd4 molecule 0.558
Itgam integrin, alpha M 0.537
Arl11 ADP-ribosylation factor-like 11 0.536
Ccl2 chemokine (C-C motif) ligand 2 0.531
Calcr calcitonin receptor 0.527
Ripk3 receptor-interacting serine-threonine kinase 3 0.527
Foxd3 forkhead box D3 0.527
St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.524
Icam1 intercellular adhesion molecule 1 0.517
Cybb cytochrome b-245, beta polypeptide 0.515
Ccr1 chemokine (C-C motif) receptor 1 0.509
Junb jun B proto-oncogene 0.507
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.505
Tbxas1 thromboxane A synthase 1, platelet 0.504
Hcls1 hematopoietic cell specific Lyn substrate 1 0.502
Igh-6 immunoglobulin heavy chain 6 0.497
Apoa5 apolipoprotein A-V 0.491
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.491
Dnase1l3 deoxyribonuclease 1-like 3 0.490
Dynll1 dynein light chain LC8-type 1 0.488
Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.483
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.476
RT1-N3 RT1 class Ib, locus N3 0.474
Il2rg interleukin 2 receptor, gamma 0.472
Gja4 gap junction protein, alpha 4 0.472
Serpina3m serine (or cysteine) proteinase inhibitor, clade A, member 3M 0.470
LOC100364854 similar to RIKEN cDNA A430107P09 gene-like 0.468
Mpeg1 macrophage expressed 1 0.466
Ptger2 prostaglandin E receptor 2 (subtype EP2) 0.464
Csf1 colony stimulating factor 1 (macrophage) 0.463
Cxcl10 chemokine (C-X-C motif) ligand 10 0.455
Rac2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.455
Mrc1 mannose receptor, C type 1 0.446
Tnni2 troponin I type 2 (skeletal, fast) 0.446
Il6 interleukin 6 0.446
Aif1 allograft inflammatory factor 1 0.446
Clec9a C-type lectin domain family 9, member a 0.442
Napsa napsin A aspartic peptidase 0.436
Adam17 ADAM metallopeptidase domain 17 0.434
Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) 0.433
Igsf6 immunoglobulin superfamily, member 6 0.433
Faslg Fas ligand (TNF superfamily, member 6) 0.430
Fcer1g Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.425
Gzmk granzyme K 0.423
Tlr4 toll-like receptor 4 0.422
Lcp2 lymphocyte cytosolic protein 2 0.422
Fgd2 FYVE, RhoGEF and PH domain containing 2 0.417
Itgb2 integrin, beta 2 0.415
F2rl2 coagulation factor II (thrombin) receptor-like 2 0.414
Cd3g CD3 molecule, gamma 0.413
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism