The network for 'serotonin transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

serotonin transport

The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.

Homo sapiens
Name Description Probability Func Analog Organism
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.999
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.997
UBASH3B ubiquitin associated and SH3 domain containing B 0.992
PILRA paired immunoglobin-like type 2 receptor alpha 0.986
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.984
PICK1 protein interacting with PRKCA 1 0.959
SIGLEC7 sialic acid binding Ig-like lectin 7 0.892
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 0.847
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 0.790
CRHR1 corticotropin releasing hormone receptor 1 0.788
FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.751
VAC14 Vac14 homolog (S. cerevisiae) 0.614
FADS2 fatty acid desaturase 2 0.579
DHCR7 7-dehydrocholesterol reductase 0.557
PTAFR platelet-activating factor receptor 0.547
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.526
BLNK B-cell linker 0.512
CD33 CD33 molecule 0.494
DRD2 dopamine receptor D2 0.486
SH3BP2 SH3-domain binding protein 2 0.473
LCK lymphocyte-specific protein tyrosine kinase 0.416
SIRPB1 signal-regulatory protein beta 1 0.414
TPPP tubulin polymerization promoting protein 0.333
TYMP thymidine phosphorylase 0.306
MAPT microtubule-associated protein tau 0.270
APLP1 amyloid beta (A4) precursor-like protein 1 0.267
CCR1 chemokine (C-C motif) receptor 1 0.238
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.232
BTK Bruton agammaglobulinemia tyrosine kinase 0.166
SNCAIP synuclein, alpha interacting protein 0.147
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.143
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) 0.138
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.137
DLG4 discs, large homolog 4 (Drosophila) 0.127
TYROBP TYRO protein tyrosine kinase binding protein 0.127
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 0.124
CD86 CD86 molecule 0.120
SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.118
DOCK7 dedicator of cytokinesis 7 0.112
GRB7 growth factor receptor-bound protein 7 0.099
HK3 hexokinase 3 (white cell) 0.098
EPOR erythropoietin receptor 0.096
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 0.092
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 0.090
TREM1 triggering receptor expressed on myeloid cells 1 0.089
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 0.088
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.088
AOAH acyloxyacyl hydrolase (neutrophil) 0.082
CYBB cytochrome b-245, beta polypeptide 0.080
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.079
PRLHR prolactin releasing hormone receptor 0.076
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.071
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 0.071
NOD2 nucleotide-binding oligomerization domain containing 2 0.071
SLA Src-like-adaptor 0.069
SYN1 synapsin I 0.066
SYK spleen tyrosine kinase 0.064
CD163 CD163 molecule 0.064
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.063
IGSF6 immunoglobulin superfamily, member 6 0.061
PRKCG protein kinase C, gamma 0.060
NLRP3 NLR family, pyrin domain containing 3 0.059
VNN2 vanin 2 0.057
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein 0.055
SLC15A3 solute carrier family 15, member 3 0.053
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.051
FPR2 formyl peptide receptor 2 0.051
PLEK pleckstrin 0.051
C3AR1 complement component 3a receptor 1 0.050
VSIG4 V-set and immunoglobulin domain containing 4 0.050
TLR8 toll-like receptor 8 0.048
CD300C CD300c molecule 0.047
AQP9 aquaporin 9 0.045
RHO rhodopsin 0.044
STX1A syntaxin 1A (brain) 0.042
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 0.042
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.042
PDE4DIP phosphodiesterase 4D interacting protein 0.042
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D 0.041
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 0.040
MARCO macrophage receptor with collagenous structure 0.040
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.040
SLC9A3 solute carrier family 9 (sodium/hydrogen exchanger), member 3 0.040
TUB tubby homolog (mouse) 0.040
CD22 CD22 molecule 0.039
BEST1 bestrophin 1 0.037
SIX6 SIX homeobox 6 0.036
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3 0.035
KCNQ2 potassium voltage-gated channel, KQT-like subfamily, member 2 0.035
AIF1 allograft inflammatory factor 1 0.034
CASP5 caspase 5, apoptosis-related cysteine peptidase 0.033
CHRNA4 cholinergic receptor, nicotinic, alpha 4 0.033
RASSF4 Ras association (RalGDS/AF-6) domain family member 4 0.032
MS4A4A membrane-spanning 4-domains, subfamily A, member 4 0.032
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.032
MAG myelin associated glycoprotein 0.032
HNF4A hepatocyte nuclear factor 4, alpha 0.031
BMP8A bone morphogenetic protein 8a 0.031
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.031
FEZF2 FEZ family zinc finger 2 0.031
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
sncgb synuclein, gamma b (breast cancer-specific protein 1) 0.051
htr1aa 5-hydroxytryptamine (serotonin) receptor 1A a 0.047
ddc dopa decarboxylase 0.034
lpar1 lysophosphatidic acid receptor 1 0.020
nlgn4b neuroligin 4b 0.019
gper G protein-coupled estrogen receptor 1 0.016
dpysl5b dihydropyrimidinase-like 5b 0.014
prom1a prominin 1a 0.014
htr1bd 5-hydroxytryptamine (serotonin) receptor 1bd 0.013
cyp4t8 cytochrome P450, family 4, subfamily T, polypeptide 8 0.012
fev FEV (ETS oncogene family) 0.012
hcrtr2 hypocretin (orexin) receptor 2 0.012
crhbp corticotropin releasing hormone binding protein 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Drd2 dopamine receptor D2 0.971
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.965
Pparg peroxisome proliferator activated receptor gamma 0.913
Mb myoglobin 0.705
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.524
Pnpla2 patatin-like phospholipase domain containing 2 0.509
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.376
Kl klotho 0.376
Emx1 empty spiracles homolog 1 (Drosophila) 0.357
Nos1 nitric oxide synthase 1, neuronal 0.356
Adrb1 adrenergic receptor, beta 1 0.332
Esr1 estrogen receptor 1 (alpha) 0.255
Hcst hematopoietic cell signal transducer 0.243
Cd247 CD247 antigen 0.213
Tbxas1 thromboxane A synthase 1, platelet 0.213
Apoe apolipoprotein E 0.212
Mefv Mediterranean fever 0.210
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.193
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.131
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.129
Kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 0.128
Nfam1 Nfat activating molecule with ITAM motif 1 0.128
Lep leptin 0.127
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.125
Adrb3 adrenergic receptor, beta 3 0.119
Npy2r neuropeptide Y receptor Y2 0.115
Trpv1 transient receptor potential cation channel, subfamily V, member 1 0.104
Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 0.095
Trem3 triggering receptor expressed on myeloid cells 3 0.092
Tyrobp TYRO protein tyrosine kinase binding protein 0.091
Sox10 SRY-box containing gene 10 0.090
ND6 NADH dehydrogenase subunit 6 0.084
Lepr leptin receptor 0.082
Lair1 leukocyte-associated Ig-like receptor 1 0.081
Clec4n C-type lectin domain family 4, member n 0.080
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.079
Kcna2 potassium voltage-gated channel, shaker-related subfamily, member 2 0.078
Mog myelin oligodendrocyte glycoprotein 0.076
Hrh1 histamine receptor H1 0.075
Msr1 macrophage scavenger receptor 1 0.069
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.069
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.066
Marco macrophage receptor with collagenous structure 0.062
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.060
Syt6 synaptotagmin VI 0.058
Cd300lb CD300 antigen like family member B 0.058
Il4 interleukin 4 0.057
Npy1r neuropeptide Y receptor Y1 0.054
Chrm1 cholinergic receptor, muscarinic 1, CNS 0.051
Adora2a adenosine A2a receptor 0.051
Lhx6 LIM homeobox protein 6 0.051
Slc22a12 solute carrier family 22 (organic anion/cation transporter), member 12 0.051
Drd1a dopamine receptor D1A 0.050
Ptgs2 prostaglandin-endoperoxide synthase 2 0.050
Emr1 EGF-like module containing, mucin-like, hormone receptor-like sequence 1 0.048
Cnr1 cannabinoid receptor 1 (brain) 0.048
Cacng5 calcium channel, voltage-dependent, gamma subunit 5 0.047
Gabrd gamma-aminobutyric acid (GABA) A receptor, subunit delta 0.047
Tectb tectorin beta 0.047
Nos2 nitric oxide synthase 2, inducible 0.047
Pcsk2 proprotein convertase subtilisin/kexin type 2 0.046
Cfh complement component factor h 0.045
Shc3 src homology 2 domain-containing transforming protein C3 0.045
Grid1 glutamate receptor, ionotropic, delta 1 0.040
F7 coagulation factor VII 0.040
Cx3cr1 chemokine (C-X3-C) receptor 1 0.040
Tbpl2 TATA box binding protein like 2 0.040
Kit kit oncogene 0.040
Siglece sialic acid binding Ig-like lectin E 0.039
Htr4 5 hydroxytryptamine (serotonin) receptor 4 0.039
Folr2 folate receptor 2 (fetal) 0.039
Htr5a 5-hydroxytryptamine (serotonin) receptor 5A 0.039
Sstr1 somatostatin receptor 1 0.038
P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 0.037
Unc79 unc-79 homolog (C. elegans) 0.036
Plau plasminogen activator, urokinase 0.036
Sstr4 somatostatin receptor 4 0.035
Adrb2 adrenergic receptor, beta 2 0.035
Ucp1 uncoupling protein 1 (mitochondrial, proton carrier) 0.034
Rab3il1 RAB3A interacting protein (rabin3)-like 1 0.034
Pick1 protein interacting with C kinase 1 0.034
Epha6 Eph receptor A6 0.034
Gp5 glycoprotein 5 (platelet) 0.034
Gsx1 GS homeobox 1 0.033
AF251705 cDNA sequence AF251705 0.032
Cd33 CD33 antigen 0.032
Gpr37l1 G protein-coupled receptor 37-like 1 0.032
Hrk harakiri, BCL2 interacting protein (contains only BH3 domain) 0.031
Grm2 glutamate receptor, metabotropic 2 0.030
2210010C04Rik RIKEN cDNA 2210010C04 gene 0.030
Glra1 glycine receptor, alpha 1 subunit 0.030
Sstr3 somatostatin receptor 3 0.030
Crhr1 corticotropin releasing hormone receptor 1 0.029
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.029
Col4a3 collagen, type IV, alpha 3 0.029
Syn2 synapsin II 0.029
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.029
Gabra2 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2 0.028
Sebox SEBOX homeobox 0.028
Galr1 galanin receptor 1 0.027
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Rattus norvegicus
Name Description Probability Func Analog Organism
Htr5a 5-hydroxytryptamine (serotonin) receptor 5A 0.045
Fev FEV (ETS oncogene family) 0.040
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.036
Dock8 dedicator of cytokinesis 8 0.035
Scn10a sodium channel, voltage-gated, type X, alpha subunit 0.029
Naaladl1 N-acetylated alpha-linked acidic dipeptidase-like 1 0.025
Gzmk granzyme K 0.025
Hrh3 histamine receptor H3 0.024
Vipr2 vasoactive intestinal peptide receptor 2 0.023
Slc14a2 solute carrier family 14 (urea transporter), member 2 0.022
Th tyrosine hydroxylase 0.021
Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 0.020
Gpr1 G protein-coupled receptor 1 0.019
Slc22a7 solute carrier family 22 (organic anion transporter), member 7 0.018
Ucn urocortin 0.018
Dcc deleted in colorectal carcinoma 0.017
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.015
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.015
Bcl2l10 BCL2-like 10 (apoptosis facilitator) 0.015
Megf6 multiple EGF-like-domains 6 0.014
Grin2c glutamate receptor, ionotropic, N-methyl D-aspartate 2C 0.014
Ptprz1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.014
Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 0.013
St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.013
Onecut1 one cut homeobox 1 0.012
Slc5a2 solute carrier family 5 (sodium/glucose cotransporter), member 2 0.012
Ncan neurocan 0.012
Pitx3 paired-like homeodomain 3 0.012
Lep leptin 0.012
Notch3 Notch homolog 3 (Drosophila) 0.012
Chrm2 cholinergic receptor, muscarinic 2 0.012
Grk4 G protein-coupled receptor kinase 4 0.012
Sag S-antigen; retina and pineal gland (arrestin) 0.011
Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 0.011
Gfra2 GDNF family receptor alpha 2 0.011
Hand1 heart and neural crest derivatives expressed 1 0.011
Folh1 folate hydrolase 1 0.010
Chrna7 cholinergic receptor, nicotinic, alpha 7 0.010
Chrne cholinergic receptor, nicotinic, epsilon 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism