The network for 'regulation of glomerulus development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of glomerulus development

Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.

Name Description Probability Func Analog Organism
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 1.000
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.000
NRP1 neuropilin 1 1.000
VEGFA vascular endothelial growth factor A 1.000
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 1.000
BMPR1A bone morphogenetic protein receptor, type IA 0.999
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.997
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.993
PGF placental growth factor 0.988
FSTL1 follistatin-like 1 0.968
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.954
BMPR1B bone morphogenetic protein receptor, type IB 0.927
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.856
WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 0.833
NOG noggin 0.829
PDGFA platelet-derived growth factor alpha polypeptide 0.770
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.751
TIMP3 TIMP metallopeptidase inhibitor 3 0.715
COL2A1 collagen, type II, alpha 1 0.667
BMP2 bone morphogenetic protein 2 0.589
BMP7 bone morphogenetic protein 7 0.560
PTPRB protein tyrosine phosphatase, receptor type, B 0.472
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.434
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.380
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.375
PDGFC platelet derived growth factor C 0.353
COL6A1 collagen, type VI, alpha 1 0.352
PLCG1 phospholipase C, gamma 1 0.342
SNAI1 snail homolog 1 (Drosophila) 0.335
COL5A1 collagen, type V, alpha 1 0.278
STC1 stanniocalcin 1 0.244
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.217
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.195
EGR3 early growth response 3 0.195
EGR2 early growth response 2 0.180
LDLR low density lipoprotein receptor 0.147
COL1A1 collagen, type I, alpha 1 0.125
COL4A1 collagen, type IV, alpha 1 0.124
SPRY4 sprouty homolog 4 (Drosophila) 0.106
TGFB2 transforming growth factor, beta 2 0.096
TAOK1 TAO kinase 1 0.095
BBS1 Bardet-Biedl syndrome 1 0.089
THBS1 thrombospondin 1 0.082
BHLHE40 basic helix-loop-helix family, member e40 0.080
FOS FBJ murine osteosarcoma viral oncogene homolog 0.074
IER2 immediate early response 2 0.073
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.069
FST follistatin 0.066
FOXF1 forkhead box F1 0.057
CDH5 cadherin 5, type 2 (vascular endothelium) 0.054
DDIT4 DNA-damage-inducible transcript 4 0.053
BMP4 bone morphogenetic protein 4 0.053
FZD4 frizzled homolog 4 (Drosophila) 0.047
COL4A2 collagen, type IV, alpha 2 0.046
JUNB jun B proto-oncogene 0.045
STC2 stanniocalcin 2 0.042
ZFP36 zinc finger protein 36, C3H type, homolog (mouse) 0.041
ROBO4 roundabout homolog 4, magic roundabout (Drosophila) 0.036
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 0.035
ZNF205 zinc finger protein 205 0.035
EFNB3 ephrin-B3 0.034
ZFYVE9 zinc finger, FYVE domain containing 9 0.033
MET met proto-oncogene (hepatocyte growth factor receptor) 0.033
VEGFC vascular endothelial growth factor C 0.033
NRP2 neuropilin 2 0.032
MDFI MyoD family inhibitor 0.032
CAV1 caveolin 1, caveolae protein, 22kDa 0.031
PTPRJ protein tyrosine phosphatase, receptor type, J 0.029
FLT4 fms-related tyrosine kinase 4 0.029
WNT2 wingless-type MMTV integration site family member 2 0.029
SLC6A8 solute carrier family 6 (neurotransmitter transporter, creatine), member 8 0.029
LOXL2 lysyl oxidase-like 2 0.026
DVL1 dishevelled, dsh homolog 1 (Drosophila) 0.026
HAND1 heart and neural crest derivatives expressed 1 0.026
BMP8B bone morphogenetic protein 8b 0.024
BMP6 bone morphogenetic protein 6 0.024
BBS4 Bardet-Biedl syndrome 4 0.024
DUSP6 dual specificity phosphatase 6 0.023
INHBB inhibin, beta B 0.023
TBX2 T-box 2 0.023
WT1 Wilms tumor 1 0.023
TGFB3 transforming growth factor, beta 3 0.022
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 0.022
EPAS1 endothelial PAS domain protein 1 0.022
GFRA1 GDNF family receptor alpha 1 0.022
NPM3 nucleophosmin/nucleoplasmin 3 0.021
FOXF2 forkhead box F2 0.021
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.021
MS4A4A membrane-spanning 4-domains, subfamily A, member 4 0.020
SLC2A4RG SLC2A4 regulator 0.020
COL13A1 collagen, type XIII, alpha 1 0.020
SLIT2 slit homolog 2 (Drosophila) 0.020
RGS16 regulator of G-protein signaling 16 0.020
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.019
SOX2 SRY (sex determining region Y)-box 2 0.019
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 0.019
TAL1 T-cell acute lymphocytic leukemia 1 0.019
EDN1 endothelin 1 0.019
GPX4 glutathione peroxidase 4 (phospholipid hydroperoxidase) 0.019
ANGPT2 angiopoietin 2 0.018
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
C1qa complement component 1, q subcomponent, alpha polypeptide 0.989
Shh sonic hedgehog 0.982
C1qc complement component 1, q subcomponent, C chain 0.960
Pax2 paired box gene 2 0.928
Ren1 renin 1 structural 0.927
Fgfr2 fibroblast growth factor receptor 2 0.920
C1qb complement component 1, q subcomponent, beta polypeptide 0.881
Lhx1 LIM homeobox protein 1 0.783
Rarg retinoic acid receptor, gamma 0.514
Wt1 Wilms tumor 1 homolog 0.487
Foxc2 forkhead box C2 0.486
Nos3 nitric oxide synthase 3, endothelial cell 0.411
Ptgs2 prostaglandin-endoperoxide synthase 2 0.338
Lepr leptin receptor 0.331
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.315
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.290
Vegfa vascular endothelial growth factor A 0.255
Gli3 GLI-Kruppel family member GLI3 0.221
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.216
Emx2 empty spiracles homolog 2 (Drosophila) 0.204
Msx1 homeobox, msh-like 1 0.200
Lmx1a LIM homeobox transcription factor 1 alpha 0.158
Tyrobp TYRO protein tyrosine kinase binding protein 0.144
Agtr1a angiotensin II receptor, type 1a 0.132
Pax3 paired box gene 3 0.114
Ret ret proto-oncogene 0.113
Emr1 EGF-like module containing, mucin-like, hormone receptor-like sequence 1 0.107
Hoxa1 homeobox A1 0.103
Foxc1 forkhead box C1 0.101
Nab2 Ngfi-A binding protein 2 0.100
Bcl2 B-cell leukemia/lymphoma 2 0.099
Egr2 early growth response 2 0.098
Hoxa11 homeobox A11 0.098
Gli2 GLI-Kruppel family member GLI2 0.092
Nos2 nitric oxide synthase 2, inducible 0.083
Sox10 SRY-box containing gene 10 0.083
Vangl2 vang-like 2 (van gogh, Drosophila) 0.082
Gbx2 gastrulation brain homeobox 2 0.080
Bdkrb2 bradykinin receptor, beta 2 0.080
Ms4a6d membrane-spanning 4-domains, subfamily A, member 6D 0.080
Ar androgen receptor 0.079
Fgfr3 fibroblast growth factor receptor 3 0.072
Gdnf glial cell line derived neurotrophic factor 0.069
Gfra3 glial cell line derived neurotrophic factor family receptor alpha 3 0.067
Ctss cathepsin S 0.067
Umod uromodulin 0.066
Phox2b paired-like homeobox 2b 0.063
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.056
Ly86 lymphocyte antigen 86 0.053
Wnt9b wingless-type MMTV integration site 9B 0.052
Egr1 early growth response 1 0.052
Bmp4 bone morphogenetic protein 4 0.051
Col4a3 collagen, type IV, alpha 3 0.051
T brachyury 0.049
Rpe65 retinal pigment epithelium 65 0.047
Agtr2 angiotensin II receptor, type 2 0.045
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.042
Rarb retinoic acid receptor, beta 0.041
Apoe apolipoprotein E 0.040
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.040
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.039
Tgfbr2 transforming growth factor, beta receptor II 0.036
Otx2 orthodenticle homolog 2 (Drosophila) 0.034
Fos FBJ osteosarcoma oncogene 0.034
Eya1 eyes absent 1 homolog (Drosophila) 0.034
Dlx5 distal-less homeobox 5 0.034
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.034
Hand1 heart and neural crest derivatives expressed transcript 1 0.033
Lhx9 LIM homeobox protein 9 0.033
Tbx1 T-box 1 0.033
Fgf10 fibroblast growth factor 10 0.031
Notch2 Notch gene homolog 2 (Drosophila) 0.030
Mrc1 mannose receptor, C type 1 0.030
Folr2 folate receptor 2 (fetal) 0.030
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.030
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.030
Aif1 allograft inflammatory factor 1 0.029
Tcfap2a transcription factor AP-2, alpha 0.029
Apln apelin 0.029
Isl1 ISL1 transcription factor, LIM/homeodomain 0.028
Csf1r colony stimulating factor 1 receptor 0.027
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.026
Nos1 nitric oxide synthase 1, neuronal 0.026
Prrx1 paired related homeobox 1 0.024
Lef1 lymphoid enhancer binding factor 1 0.024
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.023
Ptch1 patched homolog 1 0.023
Agtrap angiotensin II, type I receptor-associated protein 0.023
Bmp5 bone morphogenetic protein 5 0.020
Hoxd11 homeobox D11 0.020
Pou4f2 POU domain, class 4, transcription factor 2 0.019
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.018
Hoxa2 homeobox A2 0.018
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.017
Hes5 hairy and enhancer of split 5 (Drosophila) 0.016
Chrd chordin 0.016
Bmp7 bone morphogenetic protein 7 0.016
Hoxa3 homeobox A3 0.016
Bcl6b B-cell CLL/lymphoma 6, member B 0.015
Hic1 hypermethylated in cancer 1 0.015
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Rattus norvegicus
Name Description Probability Func Analog Organism
Junb jun B proto-oncogene 0.481
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.331
Fos FBJ osteosarcoma oncogene 0.301
Dusp6 dual specificity phosphatase 6 0.049
Btg2 BTG family, member 2 0.043
Anxa4 annexin A4 0.028
Ier2 immediate early response 2 0.028
Cyr61 cysteine-rich, angiogenic inducer, 61 0.020
Tspan8 tetraspanin 8 0.016
Fut4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.014
S100a10 S100 calcium binding protein A10 0.014
Zfp36 zinc finger protein 36 0.014
Lgals7 lectin, galactoside-binding, soluble, 7 0.013
Pnliprp2 pancreatic lipase-related protein 2 0.013
Dusp1 dual specificity phosphatase 1 0.013
Cd151 CD151 molecule (Raph blood group) 0.013
Cd5 Cd5 molecule 0.013
Plac8 placenta-specific 8 0.013
Ptpn18 protein tyrosine phosphatase, non-receptor type 18 0.013
Serpinb3 serine protease inhibitor B3 0.012
Kcnf1 potassium voltage-gated channel, subfamily F, member 1 0.012
Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 0.012
Ctse cathepsin E 0.012
Plau plasminogen activator, urokinase 0.012
LOC100360501 ribonuclease inhibitor-like 0.012
Skap2 src kinase associated phosphoprotein 2 0.012
Gmfg glia maturation factor, gamma 0.011
Zic1 Zic family member 1 (odd-paired homolog, Drosophila) 0.011
Calm4 calmodulin 4 0.011
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.011
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.011
Ocm oncomodulin 0.011
Wnt16 wingless-type MMTV integration site family, member 16 0.011
Hoxd9 homeo box D9 0.011
Prom2 prominin 2 0.010
Foxs1 forkhead box S1 0.010
Sp110 SP110 nuclear body protein 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism