IMP
Process View
The network for 'negative regulation of phagocytosis engulfment' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of phagocytosis engulfment
Any process that stops, prevents, or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| TFF1 | trefoil factor 1 | 0.986 | |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.924 | |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | 0.537 | |
| HK3 | hexokinase 3 (white cell) | 0.517 | |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 | 0.508 | |
| RIN1 | Ras and Rab interactor 1 | 0.504 | |
| MSH5 | mutS homolog 5 (E. coli) | 0.433 | |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 0.345 | |
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.195 | |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.194 | |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 | 0.167 | |
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.145 | |
| MAVS | mitochondrial antiviral signaling protein | 0.117 | |
| PTAFR | platelet-activating factor receptor | 0.115 | |
| CD300C | CD300c molecule | 0.114 | |
| CYTH4 | cytohesin 4 | 0.114 | |
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.089 | |
| SIGLEC9 | sialic acid binding Ig-like lectin 9 | 0.089 | |
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.086 | |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 | 0.069 | |
| CSF3R | colony stimulating factor 3 receptor (granulocyte) | 0.068 | |
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 | 0.065 | |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.063 | |
| CD33 | CD33 molecule | 0.063 | |
| MUC1 | mucin 1, cell surface associated | 0.061 | |
| ABI2 | abl-interactor 2 | 0.054 | |
| SASH3 | SAM and SH3 domain containing 3 | 0.054 | |
| NFAM1 | NFAT activating protein with ITAM motif 1 | 0.053 | |
| NCKAP1 | NCK-associated protein 1 | 0.050 | |
| SIGLEC5 | sialic acid binding Ig-like lectin 5 | 0.049 | |
| SPRR2A | small proline-rich protein 2A | 0.048 | |
| CD300A | CD300a molecule | 0.043 | |
| WASF1 | WAS protein family, member 1 | 0.039 | |
| APOBR | apolipoprotein B receptor | 0.038 | |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.038 | |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.037 | |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.034 | |
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 0.034 | |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.032 | |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 | 0.029 | |
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.027 | |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 | 0.027 | |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.027 | |
| SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.026 | |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 | 0.026 | |
| PILRA | paired immunoglobin-like type 2 receptor alpha | 0.025 | |
| PARVG | parvin, gamma | 0.024 | |
| APOC2 | apolipoprotein C-II | 0.023 | |
| FPR2 | formyl peptide receptor 2 | 0.022 | |
| PIK3R6 | phosphoinositide-3-kinase, regulatory subunit 6 | 0.022 | |
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.021 | |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.020 | |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.020 | |
| LRRC25 | leucine rich repeat containing 25 | 0.020 | |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 | 0.020 | |
| CD101 | CD101 molecule | 0.020 | |
| FGR | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.019 | |
| PLCB2 | phospholipase C, beta 2 | 0.019 | |
| CD180 | CD180 molecule | 0.019 | |
| LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 | 0.019 | |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) | 0.018 | |
| SPI1 | spleen focus forming virus (SFFV) proviral integration oncogene spi1 | 0.018 | |
| ASGR2 | asialoglycoprotein receptor 2 | 0.018 | |
| IL12RB1 | interleukin 12 receptor, beta 1 | 0.016 | |
| SPN | sialophorin | 0.016 | |
| LZTS2 | leucine zipper, putative tumor suppressor 2 | 0.016 | |
| RIN3 | Ras and Rab interactor 3 | 0.016 | |
| TNFAIP8L2 | tumor necrosis factor, alpha-induced protein 8-like 2 | 0.016 | |
| PTK6 | PTK6 protein tyrosine kinase 6 | 0.015 | |
| OSCAR | osteoclast associated, immunoglobulin-like receptor | 0.015 | |
| LILRA5 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 | 0.015 | |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 | 0.015 | |
| ABI3 | ABI family, member 3 | 0.015 | |
| C5AR1 | complement component 5a receptor 1 | 0.015 | |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like | 0.015 | |
| HRAS | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 0.015 | |
| FPR3 | formyl peptide receptor 3 | 0.014 | |
| FES | feline sarcoma oncogene | 0.014 | |
| SIRPB1 | signal-regulatory protein beta 1 | 0.014 | |
| TNS4 | tensin 4 | 0.014 | |
| DPEP2 | dipeptidase 2 | 0.014 | |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.014 | |
| FPR1 | formyl peptide receptor 1 | 0.014 | |
| ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit) | 0.014 | |
| EMR3 | egf-like module containing, mucin-like, hormone receptor-like 3 | 0.014 | |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.013 | |
| LILRA3 | leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 | 0.013 | |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.013 | |
| RENBP | renin binding protein | 0.013 | |
| CDK8 | cyclin-dependent kinase 8 | 0.013 | |
| CLEC5A | C-type lectin domain family 5, member A | 0.013 | |
| GPR132 | G protein-coupled receptor 132 | 0.013 | |
| GPR84 | G protein-coupled receptor 84 | 0.012 | |
| CEACAM21 | carcinoembryonic antigen-related cell adhesion molecule 21 | 0.012 | |
| SIGLEC10 | sialic acid binding Ig-like lectin 10 | 0.012 | |
| C19orf59 | chromosome 19 open reading frame 59 | 0.012 | |
| TREM2 | triggering receptor expressed on myeloid cells 2 | 0.012 | |
| SIGLEC12 | sialic acid binding Ig-like lectin 12 | 0.012 | |
| ABL2 | v-abl Abelson murine leukemia viral oncogene homolog 2 | 0.012 | |
| TLN2 | talin 2 | 0.012 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Cebpe | CCAAT/enhancer binding protein (C/EBP), epsilon | 0.018 | |
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.018 | |
| Dok1 | docking protein 1 | 0.017 | |
| Ptk2 | PTK2 protein tyrosine kinase 2 | 0.013 | |
| Gnptab | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | 0.011 |