The network for 'negative regulation of viral transcription' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of viral transcription

Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription.

Name Description Probability Func Analog Organism
HDAC1 histone deacetylase 1 0.998
HDAC2 histone deacetylase 2 0.983
IFITM1 interferon induced transmembrane protein 1 (9-27) 0.854
JUN jun proto-oncogene 0.847
CCL4 chemokine (C-C motif) ligand 4 0.736
IFITM2 interferon induced transmembrane protein 2 (1-8D) 0.706
TRIM39 tripartite motif containing 39 0.702
GFM1 G elongation factor, mitochondrial 1 0.701
CCR5 chemokine (C-C motif) receptor 5 0.648
SP1 Sp1 transcription factor 0.640
IFITM3 interferon induced transmembrane protein 3 (1-8U) 0.637
UBE2U ubiquitin-conjugating enzyme E2U (putative) 0.628
ATF3 activating transcription factor 3 0.626
MED15 mediator complex subunit 15 0.468
CXCL9 chemokine (C-X-C motif) ligand 9 0.384
SP110 SP110 nuclear body protein 0.360
CCL5 chemokine (C-C motif) ligand 5 0.345
FOS FBJ murine osteosarcoma viral oncogene homolog 0.343
TRIM43 tripartite motif containing 43 0.328
IFI16 interferon, gamma-inducible protein 16 0.322
CCL2 chemokine (C-C motif) ligand 2 0.297
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) 0.249
PAX3 paired box 3 0.245
SOX10 SRY (sex determining region Y)-box 10 0.222
ESR1 estrogen receptor 1 0.206
FOXD3 forkhead box D3 0.134
CXCL10 chemokine (C-X-C motif) ligand 10 0.134
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 0.128
IFI44L interferon-induced protein 44-like 0.126
CCL8 chemokine (C-C motif) ligand 8 0.123
IER2 immediate early response 2 0.100
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.098
DPP4 dipeptidyl-peptidase 4 0.096
ZNF263 zinc finger protein 263 0.094
HCFC1 host cell factor C1 (VP16-accessory protein) 0.088
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.087
LIN28B lin-28 homolog B (C. elegans) 0.086
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.086
TRIM5 tripartite motif containing 5 0.080
KDM6A lysine (K)-specific demethylase 6A 0.079
SP100 SP100 nuclear antigen 0.078
DDIT3 DNA-damage-inducible transcript 3 0.078
GABPA GA binding protein transcription factor, alpha subunit 60kDa 0.074
CXCL11 chemokine (C-X-C motif) ligand 11 0.067
CCL22 chemokine (C-C motif) ligand 22 0.065
TRIM21 tripartite motif containing 21 0.064
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.064
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.063
MX2 myxovirus (influenza virus) resistance 2 (mouse) 0.062
CCL3 chemokine (C-C motif) ligand 3 0.059
OCIAD1 OCIA domain containing 1 0.057
NCOR1 nuclear receptor corepressor 1 0.055
CCR7 chemokine (C-C motif) receptor 7 0.054
CCL7 chemokine (C-C motif) ligand 7 0.054
CXCL13 chemokine (C-X-C motif) ligand 13 0.052
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.051
PML promyelocytic leukemia 0.049
PLSCR1 phospholipid scramblase 1 0.046
CCL13 chemokine (C-C motif) ligand 13 0.045
ETS1 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 0.045
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.045
NAMPT nicotinamide phosphoribosyltransferase 0.044
MAPK14 mitogen-activated protein kinase 14 0.044
RAB6A RAB6A, member RAS oncogene family 0.044
IFNG interferon, gamma 0.044
TRIM34 tripartite motif containing 34 0.043
DYDC1 DPY30 domain containing 1 0.042
IL1B interleukin 1, beta 0.041
BST2 bone marrow stromal cell antigen 2 0.041
UBD ubiquitin D 0.041
SOX2 SRY (sex determining region Y)-box 2 0.040
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.040
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 0.039
ZNF473 zinc finger protein 473 0.038
TRIM22 tripartite motif containing 22 0.037
RNF5 ring finger protein 5 0.037
TRIM63 tripartite motif containing 63 0.036
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.035
CCR1 chemokine (C-C motif) receptor 1 0.035
SMAD4 SMAD family member 4 0.032
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.030
CCL19 chemokine (C-C motif) ligand 19 0.030
RAB14 RAB14, member RAS oncogene family 0.029
NCL nucleolin 0.029
IFI44 interferon-induced protein 44 0.028
VCAM1 vascular cell adhesion molecule 1 0.028
BCL6 B-cell CLL/lymphoma 6 0.028
SKIL SKI-like oncogene 0.027
TRIM8 tripartite motif containing 8 0.027
OAS1 2',5'-oligoadenylate synthetase 1, 40/46kDa 0.026
TRIM38 tripartite motif containing 38 0.026
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.026
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 0.026
GBP1 guanylate binding protein 1, interferon-inducible 0.026
MAGEA4 melanoma antigen family A, 4 0.024
XIAP X-linked inhibitor of apoptosis 0.024
CCR4 chemokine (C-C motif) receptor 4 0.024
TOP1 topoisomerase (DNA) I 0.024
RBBP4 retinoblastoma binding protein 4 0.024
IL7R interleukin 7 receptor 0.024
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Trim30a tripartite motif-containing 30A 0.962
Parp14 poly (ADP-ribose) polymerase family, member 14 0.518
Trim30d tripartite motif-containing 30D 0.495
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.474
Fos FBJ osteosarcoma oncogene 0.372
Ifi203 interferon activated gene 203 0.201
Eif2c1 eukaryotic translation initiation factor 2C, 1 0.193
Cxcl2 chemokine (C-X-C motif) ligand 2 0.168
Irf9 interferon regulatory factor 9 0.151
Atf3 activating transcription factor 3 0.142
Rsad2 radical S-adenosyl methionine domain containing 2 0.117
Tmem176b transmembrane protein 176B 0.117
Nanog Nanog homeobox 0.113
Lgals9 lectin, galactose binding, soluble 9 0.109
Htt huntingtin 0.097
Dtx3l deltex 3-like (Drosophila) 0.096
Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 0.093
Gbp3 guanylate binding protein 3 0.091
Lgals3bp lectin, galactoside-binding, soluble, 3 binding protein 0.090
Herc6 hect domain and RLD 6 0.089
H2-M3 histocompatibility 2, M region locus 3 0.088
Irf7 interferon regulatory factor 7 0.079
Ms4a4c membrane-spanning 4-domains, subfamily A, member 4C 0.078
Xaf1 XIAP associated factor 1 0.070
Stat1 signal transducer and activator of transcription 1 0.069
Trim12a tripartite motif-containing 12A 0.068
Uba7 ubiquitin-like modifier activating enzyme 7 0.068
Gbp7 guanylate binding protein 7 0.058
Dusp1 dual specificity phosphatase 1 0.058
Ezh2 enhancer of zeste homolog 2 (Drosophila) 0.054
Rhob ras homolog gene family, member B 0.054
Klf6 Kruppel-like factor 6 0.053
Ccrl2 chemokine (C-C motif) receptor-like 2 0.051
Trim21 tripartite motif-containing 21 0.051
E4f1 E4F transcription factor 1 0.049
Ifitm2 interferon induced transmembrane protein 2 0.049
Oas3 2'-5' oligoadenylate synthetase 3 0.049
Epsti1 epithelial stromal interaction 1 (breast) 0.047
Slfn2 schlafen 2 0.046
Dnmt1 DNA methyltransferase (cytosine-5) 1 0.046
Ifi44 interferon-induced protein 44 0.045
Samd9l sterile alpha motif domain containing 9-like 0.045
Trim5 tripartite motif-containing 5 0.044
Irgm1 immunity-related GTPase family M member 1 0.044
Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 0.043
Pyhin1 pyrin and HIN domain family, member 1 0.043
Ly6i lymphocyte antigen 6 complex, locus I 0.040
Ccl3 chemokine (C-C motif) ligand 3 0.039
Gzmb granzyme B 0.039
Stat2 signal transducer and activator of transcription 2 0.038
Ccl4 chemokine (C-C motif) ligand 4 0.037
Mx2 myxovirus (influenza virus) resistance 2 0.037
Zbp1 Z-DNA binding protein 1 0.035
Oas2 2'-5' oligoadenylate synthetase 2 0.035
Xcl1 chemokine (C motif) ligand 1 0.034
Btg2 B-cell translocation gene 2, anti-proliferative 0.034
Irgm2 immunity-related GTPase family M member 2 0.034
Tgtp2 T-cell specific GTPase 2 0.034
Tor3a torsin family 3, member A 0.031
Oas1b 2'-5' oligoadenylate synthetase 1B 0.031
Oasl1 2'-5' oligoadenylate synthetase-like 1 0.031
Socs1 suppressor of cytokine signaling 1 0.030
Gm12185 predicted gene 12185 0.030
Stambp STAM binding protein 0.030
Clk2 CDC-like kinase 2 0.029
Tial1 Tia1 cytotoxic granule-associated RNA binding protein-like 1 0.029
Arhgef1 Rho guanine nucleotide exchange factor (GEF) 1 0.028
Pml promyelocytic leukemia 0.028
Ifit1 interferon-induced protein with tetratricopeptide repeats 1 0.028
Sp1 trans-acting transcription factor 1 0.028
Zfp932 zinc finger protein 932 0.028
H2-T24 histocompatibility 2, T region locus 24 0.027
Gtf2e2 general transcription factor II E, polypeptide 2 (beta subunit) 0.027
Ankrd16 ankyrin repeat domain 16 0.026
Mx1 myxovirus (influenza virus) resistance 1 0.026
Mapk8 mitogen-activated protein kinase 8 0.026
Kif3b kinesin family member 3B 0.026
Cyr61 cysteine rich protein 61 0.025
Trim34a tripartite motif-containing 34A 0.025
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.025
Rnf167 ring finger protein 167 0.025
Akap8l A kinase (PRKA) anchor protein 8-like 0.025
Kdm5b lysine (K)-specific demethylase 5B 0.024
Msl1 male-specific lethal 1 homolog (Drosophila) 0.024
Zfp36 zinc finger protein 36 0.024
Aoah acyloxyacyl hydrolase 0.024
Slc12a3 solute carrier family 12, member 3 0.023
Sin3a transcriptional regulator, SIN3A (yeast) 0.023
Iigp1 interferon inducible GTPase 1 0.023
Gtpbp2 GTP binding protein 2 0.023
Rtp4 receptor transporter protein 4 0.023
D14Ertd668e DNA segment, Chr 14, ERATO Doi 668, expressed 0.023
Slfn8 schlafen 8 0.022
Rgl2 ral guanine nucleotide dissociation stimulator-like 2 0.022
Shisa5 shisa homolog 5 (Xenopus laevis) 0.022
Pydc4 pyrin domain containing 4 0.022
Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit 0.022
Gzma granzyme A 0.021
Fam193b family with sequence similarity 193, member B 0.021
Stat3 signal transducer and activator of transcription 3 0.020
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism