The network for 'cardiac ventricle formation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cardiac ventricle formation

The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.

Homo sapiens
Name Description Probability Func Analog Organism
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 1.000
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 1.000
TBX5 T-box 5 1.000
JAG1 jagged 1 0.999
GATA4 GATA binding protein 4 0.997
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.995
RUNX1 runt-related transcription factor 1 0.988
MAFA v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) 0.987
GATA2 GATA binding protein 2 0.971
SETD8 SET domain containing (lysine methyltransferase) 8 0.960
NOTCH3 notch 3 0.955
MAML1 mastermind-like 1 (Drosophila) 0.870
MYOD1 myogenic differentiation 1 0.868
XIAP X-linked inhibitor of apoptosis 0.831
GATA1 GATA binding protein 1 (globin transcription factor 1) 0.777
TAL1 T-cell acute lymphocytic leukemia 1 0.772
TCF12 transcription factor 12 0.756
HIPK2 homeodomain interacting protein kinase 2 0.718
EP300 E1A binding protein p300 0.709
HDAC4 histone deacetylase 4 0.694
TCF4 transcription factor 4 0.402
LMO2 LIM domain only 2 (rhombotin-like 1) 0.378
PDX1 pancreatic and duodenal homeobox 1 0.352
DLL1 delta-like 1 (Drosophila) 0.347
JAG2 jagged 2 0.331
HDAC9 histone deacetylase 9 0.305
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.244
MARCKSL1 MARCKS-like 1 0.242
HOXD12 homeobox D12 0.182
LMO1 LIM domain only 1 (rhombotin 1) 0.170
POU3F2 POU class 3 homeobox 2 0.161
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.131
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.129
PHOX2A paired-like homeobox 2a 0.124
PYY peptide YY 0.120
NOTCH2 notch 2 0.110
SPEN spen homolog, transcriptional regulator (Drosophila) 0.100
MEF2A myocyte enhancer factor 2A 0.098
LHX5 LIM homeobox 5 0.094
SPTBN1 spectrin, beta, non-erythrocytic 1 0.087
POU4F2 POU class 4 homeobox 2 0.075
MYLK2 myosin light chain kinase 2 0.074
SOX1 SRY (sex determining region Y)-box 1 0.072
CDK6 cyclin-dependent kinase 6 0.070
LYL1 lymphoblastic leukemia derived sequence 1 0.070
SIX6 SIX homeobox 6 0.069
HAND2 heart and neural crest derivatives expressed 2 0.068
LRRN2 leucine rich repeat neuronal 2 0.066
OTP orthopedia homeobox 0.066
HOXB9 homeobox B9 0.061
ATXN1L ataxin 1-like 0.061
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.060
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.058
EPAS1 endothelial PAS domain protein 1 0.056
FOXG1 forkhead box G1 0.055
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.053
NEUROD2 neurogenic differentiation 2 0.050
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.049
SFRP5 secreted frizzled-related protein 5 0.048
FGF3 fibroblast growth factor 3 0.047
FEV FEV (ETS oncogene family) 0.047
MYT1 myelin transcription factor 1 0.045
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.043
HOXD13 homeobox D13 0.043
SPTBN4 spectrin, beta, non-erythrocytic 4 0.041
TLX2 T-cell leukemia homeobox 2 0.040
BHLHE23 basic helix-loop-helix family, member e23 0.040
DIABLO diablo, IAP-binding mitochondrial protein 0.039
NEUROG1 neurogenin 1 0.039
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.039
FOXF2 forkhead box F2 0.039
SOX18 SRY (sex determining region Y)-box 18 0.038
KAT2B K(lysine) acetyltransferase 2B 0.038
FOXE3 forkhead box E3 0.038
EFNB3 ephrin-B3 0.037
GATA3 GATA binding protein 3 0.036
MAGED1 melanoma antigen family D, 1 0.036
EFNB2 ephrin-B2 0.036
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.036
EGFL7 EGF-like-domain, multiple 7 0.035
LMX1A LIM homeobox transcription factor 1, alpha 0.035
POU4F3 POU class 4 homeobox 3 0.035
TBX1 T-box 1 0.034
NOVA2 neuro-oncological ventral antigen 2 0.033
SLC30A3 solute carrier family 30 (zinc transporter), member 3 0.033
PPARG peroxisome proliferator-activated receptor gamma 0.033
FOXC2 forkhead box C2 (MFH-1, mesenchyme forkhead 1) 0.033
TLX1 T-cell leukemia homeobox 1 0.033
GATA5 GATA binding protein 5 0.033
FOXN4 forkhead box N4 0.031
MIF4GD MIF4G domain containing 0.031
NHLH2 nescient helix loop helix 2 0.030
HOXC11 homeobox C11 0.030
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 0.030
CDX2 caudal type homeobox 2 0.030
ZIC3 Zic family member 3 (odd-paired homolog, Drosophila) 0.030
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.029
MNX1 motor neuron and pancreas homeobox 1 0.028
SLC9A3 solute carrier family 9 (sodium/hydrogen exchanger), member 3 0.028
ALX4 ALX homeobox 4 0.028
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
tbx5a T-box 5a 0.994
mef2cb myocyte enhancer factor 2cb 0.596
kdrl kinase insert domain receptor like 0.436
foxh1 forkhead box H1 0.337
ttna titin a 0.336
mef2ca myocyte enhancer factor 2ca 0.316
myl7 myosin, light polypeptide 7, regulatory 0.273
tbx20 T-box 20 0.265
nkx2.5 NK2 transcription factor related 5 0.224
tbx1 T-box 1 0.189
hey2 hairy/enhancer-of-split related with YRPW motif 2 0.173
myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.168
tgfb3 transforming growth factor, beta 3 0.153
smyd1b SET and MYND domain containing 1b 0.148
cmlc1 cardiac myosin light chain-1 0.141
hand2 heart and neural crest derivatives expressed transcript 2 0.141
fli1a friend leukemia integration 1a 0.131
unc45b unc-45 homolog B (C. elegans) 0.130
atp2a2a ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a 0.114
ptch1 patched 1 0.105
mib mind bomb 0.101
fn1 fibronectin 1 0.083
tbx18 T-box 18 0.083
nexn nexilin (F actin binding protein) 0.080
vmhc ventricular myosin heavy chain 0.079
si:ch211-235f6.2 si:ch211-235f6.2 0.073
rerea arginine-glutamic acid dipeptide (RE) repeats a 0.069
alcama activated leukocyte cell adhesion molecule a 0.069
edn1 endothelin 1 0.065
tbx5b T-box 5b 0.062
gata6 GATA-binding protein 6 0.060
tbx2a T-box gene 2a 0.059
fgf10a fibroblast growth factor 10a 0.059
foxn4 forkhead box N4 0.051
ttnb titin b 0.050
tnnc1a troponin C type 1a (slow) 0.050
rad21 RAD21 homolog (S. pombe) 0.049
hhex hematopoietically expressed homeobox 0.049
slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 0.048
rbm24a RNA binding motif protein 24a 0.047
dlb deltaB 0.044
tie1 endothelium-specific receptor tyrosine kinase 1 0.043
ndrg4 N-myc downstream regulated gene 4 0.040
notch1a notch homolog 1a 0.038
sox9a SRY-box containing gene 9a 0.038
jag1b jagged 1b 0.037
tcf21 transcription factor 21 0.036
tbx24 T-box 24 0.035
desma desmin a 0.035
tmem88a transmembrane protein 88 a 0.035
etv2 ets variant gene 2 0.035
tpm4 tropomyosin 4 0.035
tal1 T-cell acute lymphocytic leukemia 1 0.034
myod1 myogenic differentiation 1 0.033
spaw southpaw 0.031
vmhcl ventricular myosin heavy chain-like 0.031
tnni1b troponin I, skeletal, slow b 0.031
tnnt2a troponin T2a, cardiac 0.029
fras1 Fraser syndrome 1 0.028
wu:fv91b12 wu:fv91b12 0.026
pdlim7 PDZ and LIM domain 7 0.025
col8a1a collagen, type VIII, alpha 1a 0.024
cdh5 cadherin 5 0.023
crip2 cysteine-rich protein 2 0.023
gli1 GLI-Kruppel family member 1 0.022
tgfb2 transforming growth factor, beta 2 0.022
lmo2 LIM domain only 2 (rhombotin-like 1) 0.021
ckma creatine kinase, muscle a 0.021
nkx3.2 NK3 homeobox 2 0.021
cmyb transcription factor cmyb 0.021
drl draculin 0.021
barx1 BarH-like homeobox 1 0.021
sesn1 sestrin 1 0.020
myca myelocytomatosis oncogene a 0.020
cbfb core-binding factor, beta subunit 0.019
flncb filamin C, gamma b (actin binding protein 280) 0.019
fli1b friend leukemia integration 1b 0.019
ascl1a achaete-scute complex-like 1a (Drosophila) 0.019
crb2a crumbs homolog 2a 0.019
gata4 GATA-binding protein 4 0.019
slc8a1a solute carrier family 8 (sodium/calcium exchanger), member 1a 0.019
gja3 gap junction protein, alpha 3 0.019
hspb12 heat shock protein, alpha-crystallin-related, b12 0.018
her7 hairy and enhancer of split related-7 0.018
synpo2lb synaptopodin 2-like b 0.017
gata1a GATA binding protein 1a 0.017
nkx2.3 NK2 transcription factor related 3 0.017
slc12a2 solute carrier family 12 (potassium/chloride transporters), member 2 0.016
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.016
flt4 fms-related tyrosine kinase 4 0.016
runx1 runt-related transcription factor 1 0.016
srl sarcalumenin 0.015
bmp10 bone morphogenetic protein 10 0.015
rbfox1l RNA binding protein, fox-1 homolog (C. elegans) 1-like 0.015
gdf6b growth differentiation factor 6b 0.015
fhla four and a half LIM domains a 0.015
znfl2a zinc finger-like gene 2a 0.014
flot2a flotillin 2a 0.014
tmem2 transmembrane protein 2 0.014
hoxd11a homeo box D11a 0.014
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Shh sonic hedgehog 0.999
Pitx2 paired-like homeodomain transcription factor 2 0.998
Pax3 paired box gene 3 0.991
Fgf8 fibroblast growth factor 8 0.989
Hand2 heart and neural crest derivatives expressed transcript 2 0.981
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.981
Hoxa1 homeobox A1 0.953
Tbx1 T-box 1 0.952
Otx2 orthodenticle homolog 2 (Drosophila) 0.946
Pitx1 paired-like homeodomain transcription factor 1 0.933
Isl1 ISL1 transcription factor, LIM/homeodomain 0.928
Gata4 GATA binding protein 4 0.924
Fgfr2 fibroblast growth factor receptor 2 0.918
Sall4 sal-like 4 (Drosophila) 0.911
Sox2 SRY-box containing gene 2 0.900
Foxc2 forkhead box C2 0.855
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.853
Pax2 paired box gene 2 0.807
Foxc1 forkhead box C1 0.773
Jag1 jagged 1 0.769
Pax6 paired box gene 6 0.762
Tcfap2a transcription factor AP-2, alpha 0.735
Hand1 heart and neural crest derivatives expressed transcript 1 0.720
Sox9 SRY-box containing gene 9 0.672
Chd7 chromodomain helicase DNA binding protein 7 0.641
Bmp4 bone morphogenetic protein 4 0.563
Gli3 GLI-Kruppel family member GLI3 0.551
Mesp1 mesoderm posterior 1 0.538
Eya1 eyes absent 1 homolog (Drosophila) 0.511
Foxg1 forkhead box G1 0.503
Notch1 Notch gene homolog 1 (Drosophila) 0.474
Meox2 mesenchyme homeobox 2 0.470
Vegfa vascular endothelial growth factor A 0.465
Gsc goosecoid homeobox 0.450
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.446
Alx4 aristaless-like homeobox 4 0.439
Vangl2 vang-like 2 (van gogh, Drosophila) 0.422
Fgf10 fibroblast growth factor 10 0.404
Tbx3 T-box 3 0.390
Gbx2 gastrulation brain homeobox 2 0.356
Tgfb2 transforming growth factor, beta 2 0.338
Prrx1 paired related homeobox 1 0.296
Ptf1a pancreas specific transcription factor, 1a 0.291
Fgfr1 fibroblast growth factor receptor 1 0.284
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.262
Pou5f1 POU domain, class 5, transcription factor 1 0.242
Ntf3 neurotrophin 3 0.241
Tlx3 T-cell leukemia, homeobox 3 0.237
Rarg retinoic acid receptor, gamma 0.211
Insm1 insulinoma-associated 1 0.209
Msx1 homeobox, msh-like 1 0.205
Hoxa13 homeobox A13 0.185
Nodal nodal 0.179
Rxra retinoid X receptor alpha 0.175
Gata6 GATA binding protein 6 0.175
Foxh1 forkhead box H1 0.173
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.157
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.155
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.142
Nos3 nitric oxide synthase 3, endothelial cell 0.140
Wt1 Wilms tumor 1 homolog 0.137
Lmx1b LIM homeobox transcription factor 1 beta 0.135
Lhx9 LIM homeobox protein 9 0.127
Hoxa3 homeobox A3 0.127
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.123
Emx1 empty spiracles homolog 1 (Drosophila) 0.109
Efnb2 ephrin B2 0.108
Lhx1 LIM homeobox protein 1 0.107
Nkx3-2 NK3 homeobox 2 0.102
Sall3 sal-like 3 (Drosophila) 0.095
Ednra endothelin receptor type A 0.093
Neurog2 neurogenin 2 0.092
Tbx5 T-box 5 0.092
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.090
Gli2 GLI-Kruppel family member GLI2 0.089
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.086
Lhx5 LIM homeobox protein 5 0.084
Dll4 delta-like 4 (Drosophila) 0.083
She src homology 2 domain-containing transforming protein E 0.082
Zeb1 zinc finger E-box binding homeobox 1 0.082
Dlx5 distal-less homeobox 5 0.081
Hoxa2 homeobox A2 0.081
Lmx1a LIM homeobox transcription factor 1 alpha 0.080
Chrd chordin 0.079
Rarb retinoic acid receptor, beta 0.078
Pou4f3 POU domain, class 4, transcription factor 3 0.077
Tcfcp2l1 transcription factor CP2-like 1 0.076
Pax9 paired box gene 9 0.075
Neurod1 neurogenic differentiation 1 0.073
Snai1 snail homolog 1 (Drosophila) 0.072
Runx2 runt related transcription factor 2 0.072
Nhlh1 nescient helix loop helix 1 0.072
Hoxd13 homeobox D13 0.071
Sox11 SRY-box containing gene 11 0.069
Wnt3a wingless-related MMTV integration site 3A 0.067
Alx3 aristaless-like homeobox 3 0.066
Myod1 myogenic differentiation 1 0.065
Hoxd3 homeobox D3 0.064
Ebf3 early B-cell factor 3 0.063
En1 engrailed 1 0.060
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism