IMP
Process View
The network for 'acetylcholine secretion neurotransmission' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
acetylcholine secretion neurotransmission
The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS).
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Chrnb4 | cholinergic receptor, nicotinic, beta polypeptide 4 | 1.000 | |
| Chrna3 | cholinergic receptor, nicotinic, alpha polypeptide 3 | 0.996 | |
| Drd2 | dopamine receptor D2 | 0.923 | |
| Thrb | thyroid hormone receptor beta | 0.893 | |
| Kcnma1 | potassium large conductance calcium-activated channel, subfamily M, alpha member 1 | 0.868 | |
| Ache | acetylcholinesterase | 0.855 | |
| Thra | thyroid hormone receptor alpha | 0.785 | |
| Chrna9 | cholinergic receptor, nicotinic, alpha polypeptide 9 | 0.669 | |
| Ryr1 | ryanodine receptor 1, skeletal muscle | 0.500 | |
| Tbpl2 | TATA box binding protein like 2 | 0.459 | |
| Rapsn | receptor-associated protein of the synapse | 0.414 | |
| Slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.375 | |
| Has1 | hyaluronan synthase1 | 0.372 | |
| Bsn | bassoon | 0.358 | |
| Chrnb2 | cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) | 0.340 | |
| Rac1 | RAS-related C3 botulinum substrate 1 | 0.339 | |
| Duox2 | dual oxidase 2 | 0.320 | |
| Cacng1 | calcium channel, voltage-dependent, gamma subunit 1 | 0.319 | |
| Cacnb4 | calcium channel, voltage-dependent, beta 4 subunit | 0.317 | |
| En2 | engrailed 2 | 0.310 | |
| Chrna10 | cholinergic receptor, nicotinic, alpha polypeptide 10 | 0.303 | |
| Gabrb3 | gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 | 0.302 | |
| Myog | myogenin | 0.294 | |
| Chrng | cholinergic receptor, nicotinic, gamma polypeptide | 0.271 | |
| Mybph | myosin binding protein H | 0.261 | |
| Tshr | thyroid stimulating hormone receptor | 0.253 | |
| Cacnb2 | calcium channel, voltage-dependent, beta 2 subunit | 0.229 | |
| Hcn3 | hyperpolarization-activated, cyclic nucleotide-gated K+ 3 | 0.225 | |
| Kcnj11 | potassium inwardly rectifying channel, subfamily J, member 11 | 0.224 | |
| Rho | rhodopsin | 0.221 | |
| Aff2 | AF4/FMR2 family, member 2 | 0.216 | |
| Wdr1 | WD repeat domain 1 | 0.206 | |
| Cacna2d1 | calcium channel, voltage-dependent, alpha2/delta subunit 1 | 0.205 | |
| Pax8 | paired box gene 8 | 0.200 | |
| Gnaq | guanine nucleotide binding protein, alpha q polypeptide | 0.191 | |
| Kcnk4 | potassium channel, subfamily K, member 4 | 0.173 | |
| Lpar5 | lysophosphatidic acid receptor 5 | 0.172 | |
| Cdk5r1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 0.167 | |
| Cdc42 | cell division cycle 42 homolog (S. cerevisiae) | 0.167 | |
| Smyd1 | SET and MYND domain containing 1 | 0.166 | |
| Htr5a | 5-hydroxytryptamine (serotonin) receptor 5A | 0.163 | |
| Gprin1 | G protein-regulated inducer of neurite outgrowth 1 | 0.154 | |
| Tpo | thyroid peroxidase | 0.152 | |
| Chrna6 | cholinergic receptor, nicotinic, alpha polypeptide 6 | 0.150 | |
| Homer1 | homer homolog 1 (Drosophila) | 0.144 | |
| Myf6 | myogenic factor 6 | 0.143 | |
| Neurod1 | neurogenic differentiation 1 | 0.139 | |
| Fitm1 | fat storage-inducing transmembrane protein 1 | 0.138 | |
| Cacna1b | calcium channel, voltage-dependent, N type, alpha 1B subunit | 0.136 | |
| Cga | glycoprotein hormones, alpha subunit | 0.136 | |
| Dynlt1b | dynein light chain Tctex-type 1D | 0.131 | |
| Psap | prosaposin | 0.127 | |
| Thbs2 | thrombospondin 2 | 0.126 | |
| Mas1 | MAS1 oncogene | 0.125 | |
| Slc17a8 | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 | 0.123 | |
| Gzmm | granzyme M (lymphocyte met-ase 1) | 0.122 | |
| Adcy4 | adenylate cyclase 4 | 0.116 | |
| Psapl1 | prosaposin-like 1 | 0.114 | |
| Avil | advillin | 0.109 | |
| Dcx | doublecortin | 0.108 | |
| Musk | muscle, skeletal, receptor tyrosine kinase | 0.105 | |
| Kcnj3 | potassium inwardly-rectifying channel, subfamily J, member 3 | 0.105 | |
| Art5 | ADP-ribosyltransferase 5 | 0.102 | |
| Myod1 | myogenic differentiation 1 | 0.102 | |
| Kcna2 | potassium voltage-gated channel, shaker-related subfamily, member 2 | 0.102 | |
| Cbl | Casitas B-lineage lymphoma | 0.101 | |
| St8sia3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 | 0.101 | |
| Isl2 | insulin related protein 2 (islet 2) | 0.101 | |
| Grem1 | gremlin 1 | 0.100 | |
| Vip | vasoactive intestinal polypeptide | 0.098 | |
| Tnnt3 | troponin T3, skeletal, fast | 0.093 | |
| Ankrd1 | ankyrin repeat domain 1 (cardiac muscle) | 0.090 | |
| Ryr2 | ryanodine receptor 2, cardiac | 0.090 | |
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.089 | |
| Cav1 | caveolin 1, caveolae protein | 0.089 | |
| Myh8 | myosin, heavy polypeptide 8, skeletal muscle, perinatal | 0.089 | |
| Adarb2 | adenosine deaminase, RNA-specific, B2 | 0.085 | |
| Prodh2 | proline dehydrogenase (oxidase) 2 | 0.085 | |
| Prph2 | peripherin 2 | 0.084 | |
| Gnb3 | guanine nucleotide binding protein (G protein), beta 3 | 0.082 | |
| Itpr1 | inositol 1,4,5-trisphosphate receptor 1 | 0.080 | |
| Htr1d | 5-hydroxytryptamine (serotonin) receptor 1D | 0.080 | |
| Scn8a | sodium channel, voltage-gated, type VIII, alpha | 0.079 | |
| Ebf3 | early B-cell factor 3 | 0.079 | |
| Dcc | deleted in colorectal carcinoma | 0.078 | |
| Serpina10 | serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 | 0.077 | |
| Kcnc3 | potassium voltage gated channel, Shaw-related subfamily, member 3 | 0.077 | |
| Kif5a | kinesin family member 5A | 0.076 | |
| Aipl1 | aryl hydrocarbon receptor-interacting protein-like 1 | 0.075 | |
| Alox12e | arachidonate lipoxygenase, epidermal | 0.075 | |
| Nell2 | NEL-like 2 (chicken) | 0.075 | |
| Neurog2 | neurogenin 2 | 0.074 | |
| Pramel7 | preferentially expressed antigen in melanoma like 7 | 0.073 | |
| Dnajb5 | DnaJ (Hsp40) homolog, subfamily B, member 5 | 0.072 | |
| Lcn8 | lipocalin 8 | 0.071 | |
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.070 | |
| Clcn1 | chloride channel 1 | 0.069 | |
| Pde6c | phosphodiesterase 6C, cGMP specific, cone, alpha prime | 0.069 | |
| Sfrp4 | secreted frizzled-related protein 4 | 0.069 | |
| Sag | retinal S-antigen | 0.069 |
Loading network...
Rattus norvegicus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Nfasc | neurofascin | 0.037 | |
| Kcnq3 | potassium voltage-gated channel, KQT-like subfamily, member 3 | 0.036 | |
| Syt7 | synaptotagmin VII | 0.034 | |
| Hpcal4 | hippocalcin-like 4 | 0.028 | |
| Adora1 | adenosine A1 receptor | 0.028 | |
| Strn | striatin, calmodulin binding protein | 0.024 | |
| Slc1a2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 | 0.024 | |
| Grin2b | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.022 | |
| Cyp2a1 | cytochrome P450, family 2, subfamily a, polypeptide 1 | 0.021 | |
| Begain | brain-enriched guanylate kinase-associated | 0.019 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.018 | |
| Itgam | integrin, alpha M | 0.017 | |
| Calcrl | calcitonin receptor-like | 0.017 | |
| Cx3cr1 | chemokine (C-X3-C motif) receptor 1 | 0.016 | |
| Slc6a11 | solute carrier family 6 (neurotransmitter transporter, GABA), member 11 | 0.016 | |
| Orm1 | orosomucoid 1 | 0.015 | |
| Bcan | brevican | 0.014 | |
| Drd2 | dopamine receptor D2 | 0.014 | |
| Adcyap1r1 | adenylate cyclase activating polypeptide 1 receptor 1 | 0.014 | |
| Tacr1 | tachykinin receptor 1 | 0.014 | |
| Hand1 | heart and neural crest derivatives expressed 1 | 0.013 | |
| Unc5a | unc-5 homolog A (C. elegans) | 0.013 | |
| Ptafr | platelet-activating factor receptor | 0.013 | |
| Tnr | tenascin R | 0.012 | |
| Pfkfb2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 | 0.012 | |
| Gck | glucokinase | 0.012 | |
| Uhmk1 | U2AF homology motif (UHM) kinase 1 | 0.012 | |
| B3gat1 | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | 0.012 | |
| St8sia1 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 | 0.011 | |
| Spink3 | serine peptidase inhibitor, Kazal type 3 | 0.011 | |
| Grm6 | glutamate receptor, metabotropic 6 | 0.010 |