IMP
Process View
The network for 'lipoxin a4 biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
lipoxin a4 biosynthetic process
The chemical reactions and pathways resulting in the formation of lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Alox5ap | arachidonate 5-lipoxygenase activating protein | 0.899 | |
| Orai1 | ORAI calcium release-activated calcium modulator 1 | 0.212 | |
| Tmem40 | transmembrane protein 40 | 0.173 | |
| Spib | Spi-B transcription factor (Spi-1/PU.1 related) | 0.163 | |
| Padi4 | peptidyl arginine deiminase, type IV | 0.135 | |
| Asprv1 | aspartic peptidase, retroviral-like 1 | 0.126 | |
| Ptges | prostaglandin E synthase | 0.125 | |
| Fgr | Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog | 0.109 | |
| Ltf | lactotransferrin | 0.105 | |
| Ngp | neutrophilic granule protein | 0.096 | |
| Gp9 | glycoprotein 9 (platelet) | 0.086 | |
| Cd19 | CD19 antigen | 0.074 | |
| Krt72-ps | keratin 72, pseudogene | 0.066 | |
| Chad | chondroadherin | 0.057 | |
| Fcna | ficolin A | 0.050 | |
| Camp | cathelicidin antimicrobial peptide | 0.047 | |
| Ptgir | prostaglandin I receptor (IP) | 0.046 | |
| Ly6d | lymphocyte antigen 6 complex, locus D | 0.045 | |
| Dsc3 | desmocollin 3 | 0.042 | |
| Gp1ba | glycoprotein 1b, alpha polypeptide | 0.042 | |
| Gata1 | GATA binding protein 1 | 0.040 | |
| Krtdap | keratinocyte differentiation associated protein | 0.040 | |
| Gna15 | guanine nucleotide binding protein, alpha 15 | 0.040 | |
| Retn | resistin | 0.040 | |
| Epx | eosinophil peroxidase | 0.039 | |
| Cma1 | chymase 1, mast cell | 0.039 | |
| Gfi1b | growth factor independent 1B | 0.034 | |
| Tg | thyroglobulin | 0.034 | |
| Kcna2 | potassium voltage-gated channel, shaker-related subfamily, member 2 | 0.033 | |
| Capn9 | calpain 9 | 0.033 | |
| Elane | elastase, neutrophil expressed | 0.030 | |
| P2rx1 | purinergic receptor P2X, ligand-gated ion channel, 1 | 0.030 | |
| Rab25 | RAB25, member RAS oncogene family | 0.028 | |
| Gypa | glycophorin A | 0.027 | |
| Prg2 | proteoglycan 2, bone marrow | 0.027 | |
| Tspo2 | translocator protein 2 | 0.027 | |
| Krt15 | keratin 15 | 0.026 | |
| Nfe2 | nuclear factor, erythroid derived 2 | 0.026 | |
| Mmp8 | matrix metallopeptidase 8 | 0.025 | |
| Alox15 | arachidonate 15-lipoxygenase | 0.025 | |
| Selp | selectin, platelet | 0.024 | |
| Actn2 | actinin alpha 2 | 0.024 | |
| Cxcr2 | chemokine (C-X-C motif) receptor 2 | 0.024 | |
| Mybph | myosin binding protein H | 0.021 | |
| Slc6a4 | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 0.021 | |
| Alox12e | arachidonate lipoxygenase, epidermal | 0.021 | |
| Krt4 | keratin 4 | 0.021 | |
| Cd79a | CD79A antigen (immunoglobulin-associated alpha) | 0.021 | |
| P2rx6 | purinergic receptor P2X, ligand-gated ion channel, 6 | 0.021 | |
| Dmkn | dermokine | 0.020 | |
| Expi | extracellular proteinase inhibitor | 0.020 | |
| Tnni2 | troponin I, skeletal, fast 2 | 0.020 | |
| Ctsg | cathepsin G | 0.019 | |
| Krt5 | keratin 5 | 0.017 | |
| Col17a1 | collagen, type XVII, alpha 1 | 0.017 | |
| Krt14 | keratin 14 | 0.016 | |
| Prtn3 | proteinase 3 | 0.016 | |
| Cdsn | corneodesmosin | 0.015 | |
| Calm4 | calmodulin 4 | 0.015 | |
| Nrgn | neurogranin | 0.015 | |
| Krt16 | keratin 16 | 0.014 | |
| Serpinb5 | serine (or cysteine) peptidase inhibitor, clade B, member 5 | 0.014 | |
| Aldh3a1 | aldehyde dehydrogenase family 3, subfamily A1 | 0.014 | |
| Cfd | complement factor D (adipsin) | 0.014 | |
| Myl3 | myosin, light polypeptide 3 | 0.014 | |
| Mst1r | macrophage stimulating 1 receptor (c-met-related tyrosine kinase) | 0.014 | |
| Irs3 | insulin receptor substrate 3 | 0.014 | |
| Lgals7 | lectin, galactose binding, soluble 7 | 0.014 | |
| S100a9 | S100 calcium binding protein A9 (calgranulin B) | 0.013 | |
| Ppfia4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.013 | |
| Cpa3 | carboxypeptidase A3, mast cell | 0.013 | |
| Ntsr2 | neurotensin receptor 2 | 0.013 | |
| Ltc4s | leukotriene C4 synthase | 0.012 | |
| Gli1 | GLI-Kruppel family member GLI1 | 0.012 | |
| Tbxas1 | thromboxane A synthase 1, platelet | 0.012 | |
| Csf3r | colony stimulating factor 3 receptor (granulocyte) | 0.012 | |
| Sprr1b | small proline-rich protein 1B | 0.012 | |
| Mmp9 | matrix metallopeptidase 9 | 0.012 | |
| Cpxm2 | carboxypeptidase X 2 (M14 family) | 0.012 | |
| Lyl1 | lymphoblastomic leukemia 1 | 0.012 | |
| Endou | endonuclease, polyU-specific | 0.012 | |
| Bsn | bassoon | 0.012 | |
| Slurp1 | secreted Ly6/Plaur domain containing 1 | 0.011 | |
| Gja5 | gap junction protein, alpha 5 | 0.011 | |
| Il4 | interleukin 4 | 0.011 | |
| Msh5 | mutS homolog 5 (E. coli) | 0.011 | |
| Ms4a2 | membrane-spanning 4-domains, subfamily A, member 2 | 0.011 | |
| Ifitm6 | interferon induced transmembrane protein 6 | 0.011 | |
| Spna1 | spectrin alpha 1 | 0.011 | |
| Itga2b | integrin alpha 2b | 0.011 | |
| Il9r | interleukin 9 receptor | 0.011 | |
| Prg3 | proteoglycan 3 | 0.011 | |
| Cyp2d26 | cytochrome P450, family 2, subfamily d, polypeptide 26 | 0.011 | |
| Hrc | histidine rich calcium binding protein | 0.011 | |
| Mpo | myeloperoxidase | 0.011 | |
| Psapl1 | prosaposin-like 1 | 0.011 | |
| Tnfrsf17 | tumor necrosis factor receptor superfamily, member 17 | 0.011 | |
| Aloxe3 | arachidonate lipoxygenase 3 | 0.010 | |
| Pglyrp1 | peptidoglycan recognition protein 1 | 0.010 | |
| Pkp3 | plakophilin 3 | 0.010 |
