The network for 'regulation of interleukin 8 secretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of interleukin 8 secretion

Any process that modulates the frequency, rate or extent of interleukin-8 secretion.

Name Description Probability Func Analog Organism
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.906
Pax8 paired box gene 8 0.789
Wnt4 wingless-related MMTV integration site 4 0.767
Casp1 caspase 1 0.739
Wnt3a wingless-related MMTV integration site 3A 0.728
T brachyury 0.674
Lhx1 LIM homeobox protein 1 0.649
Wnt10b wingless related MMTV integration site 10b 0.642
Shh sonic hedgehog 0.560
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.525
Aim2 absent in melanoma 2 0.497
Gbp5 guanylate binding protein 5 0.399
Dysf dysferlin 0.359
Fgf18 fibroblast growth factor 18 0.347
Gdnf glial cell line derived neurotrophic factor 0.325
Phldb2 pleckstrin homology-like domain, family B, member 2 0.270
Fzd8 frizzled homolog 8 (Drosophila) 0.257
Pou3f3 POU domain, class 3, transcription factor 3 0.257
Emx1 empty spiracles homolog 1 (Drosophila) 0.247
3110079O15Rik RIKEN cDNA 3110079O15 gene 0.203
Wnt9a wingless-type MMTV integration site 9A 0.199
Tctex1d4 Tctex1 domain containing 4 0.199
Fzd10 frizzled homolog 10 (Drosophila) 0.186
Trp73 transformation related protein 73 0.185
Kl klotho 0.180
Dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.177
Sim2 single-minded homolog 2 (Drosophila) 0.166
2310002J15Rik RIKEN cDNA 2310002J15 gene 0.164
2610109H07Rik RIKEN cDNA 2610109H07 gene 0.161
Fgf15 fibroblast growth factor 15 0.159
Scube1 signal peptide, CUB domain, EGF-like 1 0.154
Pou3f2 POU domain, class 3, transcription factor 2 0.153
Pou3f1 POU domain, class 3, transcription factor 1 0.153
Lgals3 lectin, galactose binding, soluble 3 0.148
S100a6 S100 calcium binding protein A6 (calcyclin) 0.146
Porcn porcupine homolog (Drosophila) 0.138
Zfp703 zinc finger protein 703 0.136
Csf2 colony stimulating factor 2 (granulocyte-macrophage) 0.133
Folr4 folate receptor 4 (delta) 0.132
Barx1 BarH-like homeobox 1 0.130
Bmp2 bone morphogenetic protein 2 0.127
Onecut1 one cut domain, family member 1 0.127
Wt1 Wilms tumor 1 homolog 0.127
Npas1 neuronal PAS domain protein 1 0.124
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.123
Rarb retinoic acid receptor, beta 0.119
Tnfrsf8 tumor necrosis factor receptor superfamily, member 8 0.119
Fgf8 fibroblast growth factor 8 0.117
Tnni2 troponin I, skeletal, fast 2 0.108
Neurog1 neurogenin 1 0.107
Emx2 empty spiracles homolog 2 (Drosophila) 0.106
Pax2 paired box gene 2 0.104
Wnt10a wingless related MMTV integration site 10a 0.102
Wnt2b wingless related MMTV integration site 2b 0.101
Efna4 ephrin A4 0.099
Lef1 lymphoid enhancer binding factor 1 0.099
Mdfic MyoD family inhibitor domain containing 0.097
Clic3 chloride intracellular channel 3 0.096
Mgmt O-6-methylguanine-DNA methyltransferase 0.095
Socs1 suppressor of cytokine signaling 1 0.094
Shank1 SH3/ankyrin domain gene 1 0.092
Rhoh ras homolog gene family, member H 0.092
Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric 0.091
Acan aggrecan 0.090
Lat linker for activation of T cells 0.090
Cdx1 caudal type homeobox 1 0.090
Wnt3 wingless-related MMTV integration site 3 0.089
Pdcd1 programmed cell death 1 0.088
Wnt7b wingless-related MMTV integration site 7B 0.087
Hoxc9 homeobox C9 0.087
Ms4a15 membrane-spanning 4-domains, subfamily A, member 15 0.085
Cd8a CD8 antigen, alpha chain 0.083
Ephb2 Eph receptor B2 0.083
Kcnh3 potassium voltage-gated channel, subfamily H (eag-related), member 3 0.082
Slc34a2 solute carrier family 34 (sodium phosphate), member 2 0.081
Il11 interleukin 11 0.081
Tbxa2r thromboxane A2 receptor 0.080
Amh anti-Mullerian hormone 0.079
Fgf21 fibroblast growth factor 21 0.079
Fut7 fucosyltransferase 7 0.079
Lamp2 lysosomal-associated membrane protein 2 0.077
Crlf1 cytokine receptor-like factor 1 0.075
Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 0.075
Grap2 GRB2-related adaptor protein 2 0.074
5430421N21Rik RIKEN cDNA 5430421N21 gene 0.073
Zfp771 zinc finger protein 771 0.072
5830411N06Rik RIKEN cDNA 5830411N06 gene 0.072
Lmx1a LIM homeobox transcription factor 1 alpha 0.072
Foxn4 forkhead box N4 0.071
Stra6 stimulated by retinoic acid gene 6 0.071
Crabp2 cellular retinoic acid binding protein II 0.070
Cd5 CD5 antigen 0.069
Hoxa4 homeobox A4 0.068
Asah1 N-acylsphingosine amidohydrolase 1 0.067
Hs3st6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6 0.067
Fgf3 fibroblast growth factor 3 0.066
Ppl periplakin 0.066
Serpinb6a serine (or cysteine) peptidase inhibitor, clade B, member 6a 0.066
Fzd1 frizzled homolog 1 (Drosophila) 0.065
Cd27 CD27 antigen 0.065
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
ANXA1 annexin A1 0.993
S100A10 S100 calcium binding protein A10 0.983
ANXA5 annexin A5 0.923
CRP C-reactive protein, pentraxin-related 0.674
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.596
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) 0.422
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.403
CAV1 caveolin 1, caveolae protein, 22kDa 0.350
ANXA2 annexin A2 0.349
S100A11 S100 calcium binding protein A11 0.347
ANXA4 annexin A4 0.274
MEFV Mediterranean fever 0.273
LGALS1 lectin, galactoside-binding, soluble, 1 0.270
ITGB5 integrin, beta 5 0.237
FGA fibrinogen alpha chain 0.216
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.207
CAV2 caveolin 2 0.199
NLRC4 NLR family, CARD domain containing 4 0.114
RIPK2 receptor-interacting serine-threonine kinase 2 0.083
S100A6 S100 calcium binding protein A6 0.078
FGB fibrinogen beta chain 0.077
FN1 fibronectin 1 0.075
PDCD6 programmed cell death 6 0.057
VIM vimentin 0.056
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.055
CAST calpastatin 0.052
EMP1 epithelial membrane protein 1 0.052
IQGAP1 IQ motif containing GTPase activating protein 1 0.051
NMT2 N-myristoyltransferase 2 0.044
ANXA7 annexin A7 0.044
CYFIP1 cytoplasmic FMR1 interacting protein 1 0.043
PRKCQ protein kinase C, theta 0.035
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.034
UBE2D1 ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) 0.031
CD48 CD48 molecule 0.030
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.024
PYDC2 pyrin domain containing 2 0.023
MYOF myoferlin 0.023
IL13RA1 interleukin 13 receptor, alpha 1 0.021
CD44 CD44 molecule (Indian blood group) 0.021
CD59 CD59 molecule, complement regulatory protein 0.021
APCS amyloid P component, serum 0.020
LGALS3 lectin, galactoside-binding, soluble, 3 0.020
PDCD6IP programmed cell death 6 interacting protein 0.020
AHNAK AHNAK nucleoprotein 0.018
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.017
TMSB10 thymosin beta 10 0.017
SH2D1A SH2 domain containing 1A 0.016
TUBB6 tubulin, beta 6 0.015
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.015
TSC22D1 TSC22 domain family, member 1 0.015
BAG3 BCL2-associated athanogene 3 0.015
ANXA3 annexin A3 0.015
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.014
ALG2 asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae) 0.014
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.014
VCL vinculin 0.014
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.014
LRP1 low density lipoprotein receptor-related protein 1 0.013
CLIC1 chloride intracellular channel 1 0.012
PAAF1 proteasomal ATPase-associated factor 1 0.011
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.011
ACOT9 acyl-CoA thioesterase 9 0.011
MSN moesin 0.011
LAMC3 laminin, gamma 3 0.011
FZD1 frizzled homolog 1 (Drosophila) 0.010
CD8A CD8a molecule 0.010
C4BPA complement component 4 binding protein, alpha 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism