The network for 'secondary metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

secondary metabolic process

The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.

Danio rerio
Name Description Probability Func Analog Organism
tyr tyrosinase 0.621
tnfrsfa tumor necrosis factor receptor superfamily, member a 0.456
mitfa microphthalmia-associated transcription factor a 0.452
szl sizzled 0.258
cyp1d1 cytochrome P450, family 1, subfamily D, polypeptide 1 0.256
grem2 gremlin 2, cysteine knot superfamily 0.245
pmela premelanosome protein a 0.238
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.233
tbx2b T-box 2b 0.200
star steroidogenic acute regulatory protein 0.199
efnb3b ephrin B3b 0.197
dct dopachrome tautomerase 0.197
epas1a endothelial PAS domain protein 1a 0.176
cyt1 type I cytokeratin, enveloping layer 0.146
slc24a5 solute carrier family 24, member 5 0.139
thsd7a thrombospondin, type I, domain containing 7A 0.137
kita kit receptor a 0.136
myo6b myosin VIb 0.129
rag1 recombination activating gene 1 0.125
tyrp1 tyrosinase-related protein 1 0.118
map2k4b mitogen-activated protein kinase kinase 4b 0.116
efnb2a ephrin B2a 0.116
zgc:64076 zgc:64076 0.113
cdc42 cell division cycle 42 0.107
fzd7a frizzled homolog 7a 0.105
vps39 vacuolar protein sorting 39 homolog (S. cerevisiae) 0.104
sox21a SRY-box containing gene 21a 0.103
prox2 prospero homeobox 2 0.102
cyp2y3 cytochrome P450, family 2, subfamily Y, polypeptide 3 0.098
hmx2 H6 family homeobox 2 0.098
ifnphi1 interferon phi 1 0.095
msxa muscle segment homeobox A 0.095
fzd5 frizzled homolog 5 0.091
si:ch211-93f2.1 si:ch211-93f2.1 0.090
tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.090
rgrb retinal G protein coupled receptor b 0.088
ednrb1 endothelin receptor B 0.087
cyp3a65 cytochrome P450, family 3, subfamily A, polypeptide 65 0.084
slc45a2 solute carrier family 45, member 2 0.083
ihha Indian hedgehog homolog a 0.083
ssrp1b structure specific recognition protein 1b 0.081
npy8br neuropeptide Y receptor Y8b 0.079
neurog1 neurogenin 1 0.078
LOC100000934 hypothetical protein LOC100000934 0.078
zgc:112329 zgc:112329 0.077
bty bloodthirsty 0.075
dkk1b dickkopf 1b 0.075
sfrp5 secreted frizzled-related protein 5 0.074
slc8a4b solute carrier family 8 (sodium/calcium exchanger), member 4b 0.074
lfng lunatic fringe homolog 0.073
adh8a alcohol dehydrogenase 8a 0.072
nrarpa notch-regulated ankyrin repeat protein a 0.072
abp1 amiloride binding protein 1 (amine oxidase (copper-containing)) 0.071
igfbp1b insulin-like growth factor binding protein 1b 0.070
vtg4 vitellogenin 4 0.070
arpc4 actin related protein 2/3 complex, subunit 4 0.070
atp6v0ca ATPase, H+ transporting, lysosomal, V0 subunit c, a 0.069
igfbp3 insulin-like growth factor binding protein 3 0.068
cacna1i calcium channel, voltage-dependent, T type, alpha 1I subunit 0.067
casp3a caspase 3, apoptosis-related cysteine protease a 0.067
il1b interleukin 1, beta and interleukin 1, beta 0.066
sema3d semaphorin 3d 0.066
nr5a5 nuclear receptor subfamily 5, group A, member 5 0.066
cdc42ep1 CDC42 effector protein (Rho GTPase binding) 1 0.065
kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.065
hspb6 heat shock protein, alpha-crystallin-related, b6 0.064
zgc:56622 zgc:56622 0.063
cldn8 claudin 8 0.061
bcdo2l beta-carotene 15, 15-dioxygenase 2, like 0.061
cyp51 cytochrome P450, family 51 0.060
ift46 intraflagellar transport protein 46 0.060
slc2a15b solute carrier family 2 (facilitated glucose transporter), member 15b 0.060
ppme1 protein phosphatase methylesterase 1 0.060
ppt1 palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) 0.059
dio1 deiodinase, iodothyronine, type I 0.058
esr1 estrogen receptor 1 0.058
tlr3 toll-like receptor 3 0.058
si:dkey-202c5.1 si:dkey-202c5.1 0.058
cyp4t8 cytochrome P450, family 4, subfamily T, polypeptide 8 0.057
eif4e3 eukaryotic translation initiation factor 4E family member 3 0.057
boka BCL2-related ovarian killer a 0.056
hbl3 hexose-binding lectin 3 0.056
LOC567452 G protein-coupled receptor kinase 5-like 0.056
fmr1 fragile X mental retardation 1 0.055
mitfb microphthalmia-associated transcription factor b 0.055
ctsd cathepsin D 0.055
cdc42l cell division cycle 42, like 0.055
tlr21 toll-like receptor 21 0.055
fadd Fas (tnfrsf6)-associated via death domain 0.055
wnt5a wingless-type MMTV integration site family, member 5a 0.055
agmo alkylglycerol monooxygenase 0.055
myl9l myosin, light polypeptide 9, like 0.055
runx3 runt-related transcription factor 3 0.055
sult1st3 sulfotransferase family 1, cytosolic sulfotransferase 3 0.054
dera 2-deoxyribose-5-phosphate aldolase homolog (C. elegans) 0.054
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.054
stc1l stanniocalcin 1, like 0.054
zgc:110591 zgc:110591 0.053
rbpja recombination signal binding protein for immunoglobulin kappa J region a 0.053
ncor1 nuclear receptor co-repressor 1 0.053
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
cyp-35C1 Protein CYP-35C1 0.038
cat-1 Protein CAT-1 0.030
cyp-35A3 Protein CYP-35A3 0.026
hpd-1 Protein HPD-1 0.024
C34D10.2 Protein C34D10.2 0.022
mig-2 Protein MIG-2 0.022
cyp-35A5 Protein CYP-35A5 0.022
cyp-35A2 Protein CYP-35A2 0.021
F21A3.2 Protein F21A3.2 0.019
CELE_C29F7.2 Protein C29F7.2 0.018
cyp-35A4 Protein CYP-35A4 0.017
ina-1 Protein INA-1 0.017
unc-73 Protein UNC-73 0.016
F23H11.4 Protein F23H11.4 0.015
B0511.12 Protein B0511.12 0.015
tag-77 Protein TAG-77 0.015
kel-3 Protein KEL-3 0.015
art-1 Protein ART-1 0.015
F55H12.3 Protein F55H12.3 0.014
dhs-16 Protein DHS-16 0.014
set-16 Protein SET-16 0.014
cyp-35B2 Protein CYP-35B2 0.014
vab-8 Protein VAB-8 0.014
ftn-1 Protein FTN-1 0.014
phy-2 Protein PHY-2 0.013
math-26 Protein MATH-26 0.013
cyp-34A9 Protein CYP-34A9 0.013
F08G5.6 Protein F08G5.6 0.013
clec-76 Protein CLEC-76 0.013
CELE_C08F11.3 Protein C08F11.3 0.013
dhs-23 Protein DHS-23 0.013
spo-7 Protein SPO-7 0.013
lys-7 Protein LYS-7 0.013
sulp-2 Protein SULP-2 0.013
hum-1 Protein HUM-1 0.013
pmk-1 Protein PMK-1 0.013
let-60 Protein LET-60 0.013
W01A11.1 Protein W01A11.1 0.013
nlp-39 Protein NLP-39 0.013
slr-2 Protein SLR-2 0.013
C52B9.4 Protein C52B9.4 0.013
M03B6.1 Protein M03B6.1 0.013
F35G2.5 Protein F35G2.5 0.013
npax-2 Protein NPAX-2 0.013
ppm-1 Protein PPM-1 0.013
C52E12.4 Protein C52E12.4 0.013
CELE_R09D1.8 Protein R09D1.8 0.013
CELE_M01B12.4 Protein M01B12.4 0.013
T12D8.5 Protein T12D8.5 0.013
cyp-35B1 Protein CYP-35B1 0.013
fat-6 Protein FAT-6 0.012
fzr-1 Protein FZR-1 0.012
CELE_K09C4.5 Protein K09C4.5 0.012
F47G3.3 Protein F47G3.3 0.012
F52A8.1 Protein F52A8.1 0.012
T19D12.6 Protein T19D12.6 0.012
F43C1.5 Protein F43C1.5 0.012
F46F3.3 Protein F46F3.3 0.012
fbxc-5 Protein FBXC-5 0.012
egl-1 Protein EGL-1 0.012
cyp-33C9 Protein CYP-33C9 0.012
ceh-58 Protein CEH-58 0.012
B0361.9 Protein B0361.9 0.012
cytb-5.1 Protein CYTB-5.1 0.012
F57G12.1 Protein F57G12.1 0.012
C37H5.2 Protein C37H5.2 0.012
chd-1 Protein CHD-1 0.012
ced-7 Protein CED-7 0.012
ugt-22 Protein UGT-22 0.012
K07B1.4 Protein K07B1.4 0.012
ehs-1 Protein EHS-1 0.012
imp-2 Protein IMP-2 0.012
ugt-9 Protein UGT-9 0.012
act-4 Protein ACT-4 0.012
T04F8.2 Protein T04F8.2 0.012
CELE_Y32F6A.4 Protein Y32F6A.4 0.012
pamn-1 Protein PAMN-1 0.012
apg-1 Protein APG-1 0.012
mtl-1 Protein MTL-1 0.012
fat-2 Protein FAT-2 0.012
F09F7.5 Protein F09F7.5 0.012
CELE_ZC239.14 Protein ZC239.14 0.012
tag-333 Protein TAG-333 0.011
cyp-14A1 Protein CYP-14A1 0.011
rig-4 Protein RIG-4 0.011
cyk-1 Protein CYK-1 0.011
F32A5.4 Protein F32A5.4 0.011
C05C8.1 Protein C05C8.1 0.011
sox-3 Protein SOX-3 0.011
F36A2.13 Protein F36A2.13 0.011
F52G2.3 Protein F52G2.3 0.011
cyp-33C3 Protein CYP-33C3 0.011
T16G1.6 Protein T16G1.6 0.011
ZK1053.1 Protein ZK1053.1 0.011
vab-1 Protein VAB-1 0.011
F43H9.4 Protein F43H9.4 0.011
arrd-6 Protein ARRD-6 0.011
CELE_C08H9.2 Protein C08H9.2 0.011
cdr-1 Protein CDR-1 0.011
CELE_M04F3.5 Protein M04F3.5 0.011
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
PGRP-LC Peptidoglycan recognition protein LC 1.000
proPO-A1 prophenol oxidase A1 0.990
Ephrin CG1862 gene product from transcript CG1862-RA 0.969
fon fondue 0.939
Spn28D Serpin 28D 0.936
alpha-Man-II alpha Mannosidase II 0.913
PGRP-SD CG7496 gene product from transcript CG7496-RA 0.890
RhoBTB CG5701 gene product from transcript CG5701-RA 0.885
Flo-2 flotillin 2 0.879
Sp7 Serine protease 7 0.844
Eb1 CG3265 gene product from transcript CG3265-RF 0.769
CG16904 CG16904 gene product from transcript CG16904-RA 0.714
Cyp4d21 CG6730 gene product from transcript CG6730-RA 0.702
Pten CG5671 gene product from transcript CG5671-RB 0.697
grass Gram-positive Specific Serine protease 0.688
CG18609 CG18609 gene product from transcript CG18609-RA 0.680
Exn Ephexin 0.679
alpha-Man-I alpha Mannosidase I 0.671
FucT6 alpha1,6-fucosyltransferase 0.666
dsf dissatisfaction 0.661
y yellow 0.639
Ugt35a UDP-glycosyltransferase 35a 0.634
Hml Hemolectin 0.611
Rac1 CG2248 gene product from transcript CG2248-RA 0.603
CG30008 CG30008 gene product from transcript CG30008-RA 0.578
Pu Punch 0.578
Jhe Juvenile hormone esterase 0.575
Ras85D Ras oncogene at 85D 0.561
Irc Immune-regulated catalase 0.556
AttA Attacin-A 0.551
W Wrinkled 0.547
Rel Relish 0.533
Pvr PDGF- and VEGF-receptor related 0.530
Cdc42 CG12530 gene product from transcript CG12530-RA 0.520
CG6361 CG6361 gene product from transcript CG6361-RA 0.517
CG4020 CG4020 gene product from transcript CG4020-RA 0.451
Fad2 CG7923 gene product from transcript CG7923-RA 0.446
ltd lightoid 0.428
CG13310 CG13310 gene product from transcript CG13310-RA 0.419
CG9458 CG9458 gene product from transcript CG9458-RA 0.412
arm armadillo 0.406
Spn1 Serine protease inhibitor 1 0.397
CG10562 CG10562 gene product from transcript CG10562-RA 0.375
CG42863 CG42863 gene product from transcript CG42863-RB 0.371
CG8193 CG8193 gene product from transcript CG8193-RA 0.368
Cyp4ac1 CG14032 gene product from transcript CG14032-RA 0.362
g garnet 0.362
DptB Diptericin B 0.351
Or67d Odorant receptor 67d 0.347
CG13568 CG13568 gene product from transcript CG13568-RG 0.336
Cyp12a4 CG6042 gene product from transcript CG6042-RA 0.332
kar karmoisin 0.322
eloF elongase F 0.311
Cyp6a23 CG10242 gene product from transcript CG10242-RA 0.309
Spn27A Serpin 27A 0.306
Dlic Dynein light intermediate chain 0.300
PGRP-SC1b CG8577 gene product from transcript CG8577-RA 0.280
vav CG7893 gene product from transcript CG7893-RB 0.272
CG7910 CG7910 gene product from transcript CG7910-RA 0.267
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.262
CG32185 CG32185 gene product from transcript CG32185-RA 0.261
rpr reaper 0.261
fru fruitless 0.258
Glt Glutactin 0.257
pie pineapple eye 0.256
alpha-Man-IIb CG4606 gene product from transcript CG4606-RA 0.254
Cyp6a9 Cytochrome P450-6a9 0.254
clt cricklet 0.253
MP1 Melanization Protease 1 0.251
PGRP-SA Peptidoglycan recognition protein SA 0.247
CG11327 CG11327 gene product from transcript CG11327-RA 0.242
CG15828 CG15828 gene product from transcript CG15828-RC 0.223
PGRP-SC1a CG14746 gene product from transcript CG14746-RA 0.221
Cyp9b2 Cytochrome P450-9b2 0.216
SPE Spatzle-Processing Enzyme 0.215
dia diaphanous 0.212
Nc Nedd2-like caspase 0.205
Lsp1alpha Larval serum protein 1 alpha 0.204
Acox57D-p acyl-Coenzyme A oxidase at 57D proximal 0.204
Cyp6a21 CG10247 gene product from transcript CG10247-RA 0.204
CG42377 CG42377 gene product from transcript CG42377-RA 0.203
Cyp6w1 CG8345 gene product from transcript CG8345-RA 0.202
pirk poor Imd response upon knock-in 0.200
Shc SHC-adaptor protein 0.199
CG12766 CG12766 gene product from transcript CG12766-RA 0.199
CG2064 CG2064 gene product from transcript CG2064-RA 0.199
hyd hyperplastic discs 0.196
Jheh3 Juvenile hormone epoxide hydrolase 3 0.188
Cyp12e1 CG14680 gene product from transcript CG14680-RC 0.188
Lsp1gamma Larval serum protein 1 gamma 0.185
Lis-1 Lissencephaly-1 0.184
Epac CG34392 gene product from transcript CG34392-RC 0.176
btv beethoven 0.173
CG9459 CG9459 gene product from transcript CG9459-RA 0.166
lt light 0.165
ppk23 pickpocket 23 0.164
Cyp6a2 Cytochrome P450-6a2 0.160
nec necrotic 0.159
Tsp42Ed Tetraspanin 42Ed 0.159
CG13510 CG13510 gene product from transcript CG13510-RA 0.155
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
PGK1 phosphoglycerate kinase 1 0.836
AKR1C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) 0.806
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.737
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.707
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 0.701
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.598
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.537
RHOA ras homolog gene family, member A 0.442
AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) 0.399
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.358
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.356
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.355
ARHGAP1 Rho GTPase activating protein 1 0.305
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.292
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.273
XIAP X-linked inhibitor of apoptosis 0.241
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.201
LMO2 LIM domain only 2 (rhombotin-like 1) 0.157
MAP2K4 mitogen-activated protein kinase kinase 4 0.141
JUN jun proto-oncogene 0.106
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.095
MAPK8 mitogen-activated protein kinase 8 0.080
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.077
EFNA1 ephrin-A1 0.072
NLRC4 NLR family, CARD domain containing 4 0.066
ATP8 ATP synthase F0 subunit 8 0.063
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.060
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.059
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.059
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 0.057
MAP3K1 mitogen-activated protein kinase kinase kinase 1 0.056
PRMT2 protein arginine methyltransferase 2 0.054
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.052
ARRB1 arrestin, beta 1 0.051
MAPRE3 microtubule-associated protein, RP/EB family, member 3 0.051
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.050
EGFR epidermal growth factor receptor 0.047
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.047
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 0.046
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.046
ENO1 enolase 1, (alpha) 0.043
MAPRE2 microtubule-associated protein, RP/EB family, member 2 0.043
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.041
JUP junction plakoglobin 0.041
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.039
EFNA5 ephrin-A5 0.038
DSG2 desmoglein 2 0.037
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.036
NCF4 neutrophil cytosolic factor 4, 40kDa 0.035
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.035
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.032
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.029
ANAPC4 anaphase promoting complex subunit 4 0.028
C6 complement component 6 0.027
EZR ezrin 0.027
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.027
DSP desmoplakin 0.024
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.024
ZNF746 zinc finger protein 746 0.023
CTNND1 catenin (cadherin-associated protein), delta 1 0.023
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.023
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.022
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.022
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.022
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 0.020
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.020
EPHA7 EPH receptor A7 0.020
GLYAT glycine-N-acyltransferase 0.019
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 0.019
IL1RAP interleukin 1 receptor accessory protein 0.018
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.018
CFLAR CASP8 and FADD-like apoptosis regulator 0.018
CDH5 cadherin 5, type 2 (vascular endothelium) 0.018
RAI1 retinoic acid induced 1 0.018
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.016
ADH6 alcohol dehydrogenase 6 (class V) 0.016
SH3BP2 SH3-domain binding protein 2 0.015
ELF4 E74-like factor 4 (ets domain transcription factor) 0.015
AADAC arylacetamide deacetylase (esterase) 0.015
IFI16 interferon, gamma-inducible protein 16 0.015
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.015
RAB27A RAB27A, member RAS oncogene family 0.014
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.014
F9 coagulation factor IX 0.014
GSK3B glycogen synthase kinase 3 beta 0.013
GJB3 gap junction protein, beta 3, 31kDa 0.013
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7 0.013
FIBP fibroblast growth factor (acidic) intracellular binding protein 0.013
IQGAP1 IQ motif containing GTPase activating protein 1 0.012
HRG histidine-rich glycoprotein 0.012
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 0.012
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.012
FMO4 flavin containing monooxygenase 4 0.012
C8A complement component 8, alpha polypeptide 0.012
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.012
PVRL3 poliovirus receptor-related 3 0.011
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.011
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.011
PTN pleiotrophin 0.011
AMBRA1 autophagy/beclin-1 regulator 1 0.011
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Tyr tyrosinase 0.999
Lyst lysosomal trafficking regulator 0.998
Mitf microphthalmia-associated transcription factor 0.985
Tyrp1 tyrosinase-related protein 1 0.982
Rac1 RAS-related C3 botulinum substrate 1 0.842
Casp1 caspase 1 0.792
Oca2 oculocutaneous albinism II 0.750
Cyp2d10 cytochrome P450, family 2, subfamily d, polypeptide 10 0.748
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.690
Mc1r melanocortin 1 receptor 0.687
a nonagouti 0.641
Kit kit oncogene 0.639
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.611
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.570
Gbp5 guanylate binding protein 5 0.555
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.472
Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 0.463
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.449
Bax BCL2-associated X protein 0.440
Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 0.387
Bcl2 B-cell leukemia/lymphoma 2 0.369
Cyp3a25 cytochrome P450, family 3, subfamily a, polypeptide 25 0.368
Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 0.344
Otc ornithine transcarbamylase 0.286
Pycard PYD and CARD domain containing 0.267
Aadac arylacetamide deacetylase (esterase) 0.265
Tlr4 toll-like receptor 4 0.225
Ctnnb1 catenin (cadherin associated protein), beta 1 0.225
Pcsk5 proprotein convertase subtilisin/kexin type 5 0.223
Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic 0.207
Slc26a4 solute carrier family 26, member 4 0.204
Vav2 vav 2 oncogene 0.194
Cyp2c50 cytochrome P450, family 2, subfamily c, polypeptide 50 0.189
Efnb2 ephrin B2 0.188
Akr1c6 aldo-keto reductase family 1, member C6 0.170
Cps1 carbamoyl-phosphate synthetase 1 0.169
Grb2 growth factor receptor bound protein 2 0.169
Arhgap1 Rho GTPase activating protein 1 0.166
Trp53 transformation related protein 53 0.162
Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 0.155
Fmo5 flavin containing monooxygenase 5 0.140
Pomc pro-opiomelanocortin-alpha 0.138
Gata4 GATA binding protein 4 0.138
Cyp2f2 cytochrome P450, family 2, subfamily f, polypeptide 2 0.137
Cyp2a12 cytochrome P450, family 2, subfamily a, polypeptide 12 0.132
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.129
Hpd 4-hydroxyphenylpyruvic acid dioxygenase 0.127
Ephb2 Eph receptor B2 0.125
Aim2 absent in melanoma 2 0.124
Pou2af1 POU domain, class 2, associating factor 1 0.123
Vav3 vav 3 oncogene 0.116
Inhbc inhibin beta-C 0.115
Slc45a2 solute carrier family 45, member 2 0.108
Il7 interleukin 7 0.107
Pmel premelanosome protein 0.106
Mlph melanophilin 0.105
Pgk1 phosphoglycerate kinase 1 0.104
Bak1 BCL2-antagonist/killer 1 0.103
Lepr leptin receptor 0.098
Cxcl13 chemokine (C-X-C motif) ligand 13 0.088
Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 0.088
Gsta2 glutathione S-transferase, alpha 2 (Yc2) 0.087
Shc3 src homology 2 domain-containing transforming protein C3 0.086
Myo5a myosin VA 0.086
Baat bile acid-Coenzyme A: amino acid N-acyltransferase 0.084
Efnb1 ephrin B1 0.082
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.080
Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 0.079
Abcc6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 0.079
Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.076
Cdsn corneodesmosin 0.075
Hrg histidine-rich glycoprotein 0.069
Lta lymphotoxin A 0.068
Rdh7 retinol dehydrogenase 7 0.068
Cbl Casitas B-lineage lymphoma 0.066
F13b coagulation factor XIII, beta subunit 0.066
Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 0.065
Gsta4 glutathione S-transferase, alpha 4 0.065
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.062
Chga chromogranin A 0.055
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.055
Msn moesin 0.053
Tdo2 tryptophan 2,3-dioxygenase 0.053
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.052
Nr1i3 nuclear receptor subfamily 1, group I, member 3 0.052
Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 0.051
Slc24a5 solute carrier family 24, member 5 0.051
Adra2b adrenergic receptor, alpha 2b 0.051
Plcg1 phospholipase C, gamma 1 0.050
Ces1d carboxylesterase 1D 0.049
Eda ectodysplasin-A 0.049
Sult1a1 sulfotransferase family 1A, phenol-preferring, member 1 0.049
Cd19 CD19 antigen 0.048
Vav1 vav 1 oncogene 0.048
Aqp8 aquaporin 8 0.047
Alb albumin 0.047
Il18 interleukin 18 0.046
Mbl2 mannose-binding lectin (protein C) 2 0.045
Ikbkb inhibitor of kappaB kinase beta 0.045
Il4 interleukin 4 0.045
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Rattus norvegicus
Name Description Probability Func Analog Organism
Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 0.299
Gsta5 glutathione S-transferase Yc2 subunit 0.223
Apob apolipoprotein B 0.193
Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 0.190
Mgst2 microsomal glutathione S-transferase 2 0.181
Ugt2b5 UDP glucuronosyltransferase 2 family, polypeptide B5 0.119
Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 0.108
Omd osteomodulin 0.103
Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 0.096
Sult1a1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.093
Otc ornithine carbamoyltransferase 0.088
Gsta2 glutathione S-transferase A2 0.088
Ugt2b UDP glycosyltransferase 2 family, polypeptide B 0.077
Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 0.076
Akr1c18 aldo-keto reductase family 1, member C18 0.076
Sult1c3 sulfotransferase family, cytosolic, 1C, member 3 0.075
LOC100361547 Cytochrome P450, family 2, subfamily c, polypeptide 7-like 0.073
Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 0.073
Sult1b1 sulfotransferase family, cytosolic, 1B, member 1 0.069
Cyp3a23/3a1 cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 0.064
Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 0.063
Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 0.062
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.055
Sult1e1 sulfotransferase family 1E, estrogen-preferring, member 1 0.054
Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 0.052
Ugt2b36 UDP glucuronosyltransferase 2 family, polypeptide B36 0.050
LOC494499 LOC494499 protein 0.046
Ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 0.045
LOC293989 cytochrome P450-like 0.043
Akr1c12 aldo-keto reductase family 1, member C12 0.042
Ces1e carboxylesterase 1E 0.042
Faslg Fas ligand (TNF superfamily, member 6) 0.040
A1i3 alpha-1-inhibitor III 0.040
Aqp9 aquaporin 9 0.040
Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 0.040
Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 0.038
LOC100365112 carboxylesterase-like 0.037
Slco1a1 solute carrier organic anion transporter family, member 1a1 0.037
LOC246267 resection-induced TPI (rs11) 0.036
Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 0.035
Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 0.034
Mettl7b methyltransferase like 7B 0.034
Fmo3 flavin containing monooxygenase 3 0.034
Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 0.031
Arpc2 actin related protein 2/3 complex, subunit 2 0.030
Pigr polymeric immunoglobulin receptor 0.030
Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 0.029
Fabp1 fatty acid binding protein 1, liver 0.029
Ces1f carboxylesterase 1F 0.029
Kmo kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.029
Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 0.028
Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 0.027
Crygf crystallin, gamma F 0.026
Mgst1 microsomal glutathione S-transferase 1 0.026
Apoa2 apolipoprotein A-II 0.026
LOC100361864 UDP-glucuronosyltransferase 2B3-like 0.026
Sult2al1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 1 0.025
Tmed2 transmembrane emp24 domain trafficking protein 2 0.025
Cd14 CD14 molecule 0.025
Ces1c carboxylesterase 1C 0.025
Ugt1a3 UDP glycosyltransferase 1 family, polypeptide A3 0.024
Olr1701 olfactory receptor 1701 0.024
Vamp3 vesicle-associated membrane protein 3 0.023
Adh1 alcohol dehydrogenase 1 (class I) 0.023
Vom1r93 vomeronasal 1 receptor 93 0.023
Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 0.022
Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C 0.021
Dstn destrin 0.021
Galnt5 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5) 0.020
Gstp1 glutathione S-transferase pi 1 0.020
Sult1c2 sulfotransferase family, cytosolic, 1C, member 2 0.020
Phex phosphate regulating endopeptidase homolog, X-linked 0.020
Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 0.020
Slc22a18 solute carrier family 22, member 18 0.019
Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.019
Klk8 kallikrein related-peptidase 8 0.019
Akap14 A kinase (PRKA) anchor protein 14 0.018
Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 0.018
Ephx1 epoxide hydrolase 1, microsomal 0.018
L3mbtl3 l(3)mbt-like 3 (Drosophila) 0.018
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.018
Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 0.018
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.017
Gsta3 glutathione S-transferase A3 0.017
Ugt2b7 UDP glucuronosyltransferase 2 family, polypeptide B7 0.017
Rhog ras homolog gene family, member G (rho G) 0.016
Prkacb protein kinase, cAMP dependent, catalytic, beta 0.016
Fasn fatty acid synthase 0.015
Cybrd1 cytochrome b reductase 1 0.015
Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 0.015
Tat tyrosine aminotransferase 0.014
Egfr epidermal growth factor receptor 0.014
Serpinb1a serine (or cysteine) proteinase inhibitor, clade B, member 1a 0.014
Nr0b2 nuclear receptor subfamily 0, group B, member 2 0.014
Pgcp plasma glutamate carboxypeptidase 0.014
Pck1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.013
Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 0.013
Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 0.013
Rag1 recombination activating gene 1 0.013
Mosc1 MOCO sulphurase C-terminal domain containing 1 0.013
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
AAD14 Aad14p 0.014