The network for 'pronephros morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

pronephros morphogenesis

The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.

Danio rerio
Name Description Probability Func Analog Organism
ntla no tail a 0.766
osr2 odd-skipped related 2 (Drosophila) 0.761
tbx16 T-box gene 16 0.747
hnf1ba HNF1 homeobox Ba 0.711
tbx2a T-box gene 2a 0.595
bmp4 bone morphogenetic protein 4 0.481
pax2a paired box gene 2a 0.290
lhx1a LIM homeobox 1a 0.273
flh floating head 0.213
wt1a wilms tumor 1a 0.169
her7 hairy and enhancer of split related-7 0.165
ror2 receptor tyrosine kinase-like orphan receptor 2 0.165
myl7 myosin, light polypeptide 7, regulatory 0.142
fgf8a fibroblast growth factor 8 a 0.137
shha sonic hedgehog a 0.117
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.116
her1 hairy-related 1 0.116
hnf1bb HNF1 homeobox Bb 0.116
chd chordin 0.115
gbx2 gastrulation brain homeo box 2 0.114
eng2a engrailed 2a 0.104
lrrc6 leucine rich repeat containing 6 0.102
wt1b wilms tumor 1b 0.091
irx4b iroquois homeobox protein 4b 0.089
tll1 tolloid-like 1 0.084
cyp26a1 cytochrome P450, subfamily XXVIA, polypeptide 1 0.084
hapln1a hyaluronan and proteoglycan link protein 1a 0.065
snai1a snail homolog 1a (Drosophila) 0.065
tbx2b T-box 2b 0.064
pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.061
rxraa retinoid X receptor, alpha a 0.060
tbx20 T-box 20 0.058
ndr1 nodal-related 1 0.056
sox9a SRY-box containing gene 9a 0.053
prrx1b paired related homeobox 1b 0.053
pou3f3b POU class 3 homeobox 3b 0.053
sept6 septin 6 0.053
vsx1 visual system homeobox 1 homolog, chx10-like 0.051
vcanb versican b 0.050
bbs7 Bardet-Biedl syndrome 7 0.050
hoxd12a homeo box D12a 0.049
sox10 SRY-box containing gene 10 0.048
hoxa11b homeo box A11b 0.047
msgn1 mesogenin 1 0.046
hoxa9b homeo box A9b 0.045
lrrc50 leucine rich repeat containing 50 0.045
hoxd11a homeo box D11a 0.044
notch1a notch homolog 1a 0.043
jag2 jagged 2 0.043
ttc21b tetratricopeptide repeat domain 21B 0.041
map9 microtubule-associated protein 9 0.041
eomesa eomesodermin homolog a 0.041
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.040
has2 hyaluronan synthase 2 0.039
myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.039
igf1rb insulin-like growth factor 1b receptor 0.039
ift52 intraflagellar transport protein 52 0.037
mib mind bomb 0.036
lnpa limb and neural patterns a 0.036
mmp2 matrix metalloproteinase 2 0.035
arl13b ADP-ribosylation factor-like 13b 0.035
myod1 myogenic differentiation 1 0.034
cdx4 caudal type homeo box transcription factor 4 0.034
mbtps1 membrane-bound transcription factor protease, site 1 0.034
dcc deleted in colorectal carcinoma 0.034
wu:fb01h12 wu:fb01h12 0.034
sema3d semaphorin 3d 0.033
irx1a iroquois homeobox protein 1, a 0.033
rbpja recombination signal binding protein for immunoglobulin kappa J region a 0.032
si:ch211-255l12.1 si:ch211-255l12.1 0.032
ccdc40 coiled-coil domain containing 40 0.032
tcf21 transcription factor 21 0.031
hoxa10b homeo box A10b 0.031
gsc goosecoid 0.031
si:ch211-285f17.1 si:ch211-285f17.1 0.030
hmx4 H6 family homeobox 4 0.030
hand2 heart and neural crest derivatives expressed transcript 2 0.030
metap2 methionyl aminopeptidase 2 0.029
myf5 myogenic factor 5 0.029
nkx2.5 NK2 transcription factor related 5 0.028
gstt1b glutathione S-transferase theta 1b 0.028
grnb granulin b 0.028
wnt9a wingless-type MMTV integration site family, member 9A 0.027
gon4l gon-4-like (C.elegans) 0.027
sp5l Sp5 transcription factor-like 0.027
hoxa13a homeo box A13a 0.027
dlx6a distal-less homeobox gene 6a 0.026
prox2 prospero homeobox 2 0.026
fgf10a fibroblast growth factor 10a 0.026
stk36 serine/threonine kinase 36 (fused homolog, Drosophila) 0.025
pax8 paired box gene 8 0.025
pcdh8 protocadherin 8 0.025
osr1 odd-skipped related 1 (Drosophila) 0.024
slc4a4a solute carrier family 4, member 4a 0.024
smad9 MAD homolog 9 (Drosophila) 0.023
ncam1b neural cell adhesion molecule 1b 0.023
snx1 sorting nexin 1 0.023
neurod6b neurogenic differentiation 6b 0.023
bmp2b bone morphogenetic protein 2b 0.023
rxrba retinoid x receptor, beta a 0.023
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
HNF4A hepatocyte nuclear factor 4, alpha 0.318
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.123
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 0.018
PAM peptidylglycine alpha-amidating monooxygenase 0.017
PCBD2 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 0.016
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.015
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.012
HNF1B HNF1 homeobox B 0.011
NKTR natural killer-tumor recognition sequence 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Shh sonic hedgehog 0.909
Rarg retinoic acid receptor, gamma 0.892
Pax3 paired box gene 3 0.858
Foxc1 forkhead box C1 0.854
Tbx1 T-box 1 0.826
Hoxa1 homeobox A1 0.825
Jag1 jagged 1 0.768
Fgfr2 fibroblast growth factor receptor 2 0.764
Invs inversin 0.761
Eya1 eyes absent 1 homolog (Drosophila) 0.760
Fgf8 fibroblast growth factor 8 0.749
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.698
Foxc2 forkhead box C2 0.601
Pitx2 paired-like homeodomain transcription factor 2 0.588
Fgfr1 fibroblast growth factor receptor 1 0.545
Foxg1 forkhead box G1 0.529
Chd7 chromodomain helicase DNA binding protein 7 0.521
Bmp4 bone morphogenetic protein 4 0.487
Vangl2 vang-like 2 (van gogh, Drosophila) 0.464
Emx2 empty spiracles homolog 2 (Drosophila) 0.448
Gbx2 gastrulation brain homeobox 2 0.442
Gli3 GLI-Kruppel family member GLI3 0.380
Rarb retinoic acid receptor, beta 0.337
Mks1 Meckel syndrome, type 1 0.329
Lhx1 LIM homeobox protein 1 0.305
Smo smoothened homolog (Drosophila) 0.290
Rara retinoic acid receptor, alpha 0.268
Rxra retinoid X receptor alpha 0.207
Otx1 orthodenticle homolog 1 (Drosophila) 0.205
Zeb1 zinc finger E-box binding homeobox 1 0.175
Otx2 orthodenticle homolog 2 (Drosophila) 0.161
Ednra endothelin receptor type A 0.156
Gata3 GATA binding protein 3 0.150
Efnb2 ephrin B2 0.135
Ece1 endothelin converting enzyme 1 0.122
Pkd1 polycystic kidney disease 1 homolog 0.121
Bicc1 bicaudal C homolog 1 (Drosophila) 0.117
Tbx10 T-box 10 0.101
Hoxa3 homeobox A3 0.100
Sox2 SRY-box containing gene 2 0.095
Fgf10 fibroblast growth factor 10 0.092
Pax2 paired box gene 2 0.086
Tgfb2 transforming growth factor, beta 2 0.083
Chrd chordin 0.082
Prrx2 paired related homeobox 2 0.078
Vegfa vascular endothelial growth factor A 0.071
Bmp7 bone morphogenetic protein 7 0.065
Isl1 ISL1 transcription factor, LIM/homeodomain 0.057
Tcfap2a transcription factor AP-2, alpha 0.056
Sox9 SRY-box containing gene 9 0.054
Dlx5 distal-less homeobox 5 0.049
Hes1 hairy and enhancer of split 1 (Drosophila) 0.048
Tgfbr2 transforming growth factor, beta receptor II 0.040
Hand2 heart and neural crest derivatives expressed transcript 2 0.039
Gli2 GLI-Kruppel family member GLI2 0.036
Meox2 mesenchyme homeobox 2 0.026
Rdh10 retinol dehydrogenase 10 (all-trans) 0.026
Ret ret proto-oncogene 0.026
Fgf3 fibroblast growth factor 3 0.024
Sox11 SRY-box containing gene 11 0.023
Pax8 paired box gene 8 0.022
Hmx3 H6 homeobox 3 0.021
Tctn1 tectonic family member 1 0.021
Ctnnb1 catenin (cadherin associated protein), beta 1 0.020
Acvr1 activin A receptor, type 1 0.020
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.019
Lmx1a LIM homeobox transcription factor 1 alpha 0.019
Fgfr3 fibroblast growth factor receptor 3 0.019
Wt1 Wilms tumor 1 homolog 0.019
Sox4 SRY-box containing gene 4 0.017
Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 0.016
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.016
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.015
Nrp1 neuropilin 1 0.015
Prrx1 paired related homeobox 1 0.015
Wnt9b wingless-type MMTV integration site 9B 0.015
Psen1 presenilin 1 0.014
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.014
Fbln1 fibulin 1 0.014
Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.014
Gsc goosecoid homeobox 0.013
Cys1 cystin 1 0.013
Pbx1 pre B-cell leukemia transcription factor 1 0.013
Megf8 multiple EGF-like-domains 8 0.012
Nog noggin 0.011
Hoxa2 homeobox A2 0.011
Wnt5a wingless-related MMTV integration site 5A 0.011
Hoxb3 homeobox B3 0.011
Bcl2 B-cell leukemia/lymphoma 2 0.011
Bdnf brain derived neurotrophic factor 0.010
Hoxd11 homeobox D11 0.010
Pax6 paired box gene 6 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism