IMP

Process View

Homo sapiens

7 genes annotated in human

positive regulation of neutrophil chemotaxis

Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of neutrophil chemotaxis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of neutrophil chemotaxis" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	1.000	Human
CCL5	chemokine (C-C motif) ligand 5	0.998	Human
CCL4	chemokine (C-C motif) ligand 4	0.949	Human
IL1B	interleukin 1, beta	0.918	Rat
CXCL9	chemokine (C-X-C motif) ligand 9	0.911
CCR7	chemokine (C-C motif) receptor 7	0.857
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.832
CXCR4	chemokine (C-X-C motif) receptor 4	0.783	Human
CCL22	chemokine (C-C motif) ligand 22	0.758	Human
IL8	interleukin 8	0.642
CCR4	chemokine (C-C motif) receptor 4	0.587	Human
CCL8	chemokine (C-C motif) ligand 8	0.506	Human
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.486
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.469	Human
CCL2	chemokine (C-C motif) ligand 2	0.450	Human
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.421
IFNG	interferon, gamma	0.411
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.401
IL2RB	interleukin 2 receptor, beta	0.400
CCL7	chemokine (C-C motif) ligand 7	0.378	Human
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.337
CCL3	chemokine (C-C motif) ligand 3	0.310	Human
CXCL2	chemokine (C-X-C motif) ligand 2	0.292
CCL19	chemokine (C-C motif) ligand 19	0.284
IL2RG	interleukin 2 receptor, gamma	0.271
PLEK	pleckstrin	0.247
CCL11	chemokine (C-C motif) ligand 11	0.231	Human
CCR1	chemokine (C-C motif) receptor 1	0.200	Human
IL6	interleukin 6 (interferon, beta 2)	0.186
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.179
CCL13	chemokine (C-C motif) ligand 13	0.174	Human
CXCL13	chemokine (C-X-C motif) ligand 13	0.162
IL1RN	interleukin 1 receptor antagonist	0.154
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.153	Human
IL1R1	interleukin 1 receptor, type I	0.150
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.149
CXCL10	chemokine (C-X-C motif) ligand 10	0.147
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.126
CXCL3	chemokine (C-X-C motif) ligand 3	0.123
CCR2	chemokine (C-C motif) receptor 2	0.123	Human
TNF	tumor necrosis factor	0.113
IL10	interleukin 10	0.109
CCL20	chemokine (C-C motif) ligand 20	0.103	Human
IL1R2	interleukin 1 receptor, type II	0.101
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.086
HLA-DRB1	major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1	0.086
DPP4	dipeptidyl-peptidase 4	0.079
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.072
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.072	Mouse
CXCL11	chemokine (C-X-C motif) ligand 11	0.062
ICAM1	intercellular adhesion molecule 1	0.062
TGFB1	transforming growth factor, beta 1	0.058
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.054
CD40LG	CD40 ligand	0.052
VCAM1	vascular cell adhesion molecule 1	0.047
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.043
SELE	selectin E	0.038
AQP9	aquaporin 9	0.036
IRF4	interferon regulatory factor 4	0.036
CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	0.035
CXCL5	chemokine (C-X-C motif) ligand 5	0.033
CXCR3	chemokine (C-X-C motif) receptor 3	0.032	Human
BCL2A1	BCL2-related protein A1	0.032
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.031
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.030
TLR2	toll-like receptor 2	0.030
IDE	insulin-degrading enzyme	0.029
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.029
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.029
IL7R	interleukin 7 receptor	0.027
IL10RA	interleukin 10 receptor, alpha	0.026
SLAMF7	SLAM family member 7	0.026
CCL21	chemokine (C-C motif) ligand 21	0.024
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.021
CD93	CD93 molecule	0.020
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.020
RGS1	regulator of G-protein signaling 1	0.019
UBD	ubiquitin D	0.018
C3AR1	complement component 3a receptor 1	0.018	Mouse
PLAUR	plasminogen activator, urokinase receptor	0.018
CCR3	chemokine (C-C motif) receptor 3	0.018	Human
TLR4	toll-like receptor 4	0.017
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.017
RUNX3	runt-related transcription factor 3	0.017
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.017
IL18RAP	interleukin 18 receptor accessory protein	0.017
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.015
IRAK2	interleukin-1 receptor-associated kinase 2	0.015
MYD88	myeloid differentiation primary response gene (88)	0.014
RHOC	ras homolog gene family, member C	0.014
RHOA	ras homolog gene family, member A	0.014
IL21R	interleukin 21 receptor	0.013
CXCR2	chemokine (C-X-C motif) receptor 2	0.013	Human Rat
IL1A	interleukin 1, alpha	0.013
FPR1	formyl peptide receptor 1	0.013
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.013
DARC	Duffy blood group, chemokine receptor	0.013
LTB	lymphotoxin beta (TNF superfamily, member 3)	0.012
RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.012
EBI3	Epstein-Barr virus induced 3	0.011
JUP	junction plakoglobin	0.011
IL1RAP	interleukin 1 receptor accessory protein	0.011
CD48	CD48 molecule	0.011
CH25H	cholesterol 25-hydroxylase	0.011
SOCS3	suppressor of cytokine signaling 3	0.010
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.010
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.010