IMP
Process View
intracellular signal transduction involved in g1 dna damage checkpoint
Any intracellular signal transduction that is involved in G1 DNA damage checkpoint.
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Click on a gene's description to view its network relationships with genes known to be involved in "intracellular signal transduction involved in g1 dna damage checkpoint"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| TP53 | tumor protein p53 | 1.000 | Mouse | |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.998 | Human | |
| RB1 | retinoblastoma 1 | 0.964 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.934 | ||
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.925 | Human | |
| XIAP | X-linked inhibitor of apoptosis | 0.868 | ||
| PAX3 | paired box 3 | 0.795 | ||
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.771 | ||
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | 0.419 | ||
| LRDD | leucine-rich repeats and death domain containing | 0.383 | ||
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.374 | ||
| APAF1 | apoptotic peptidase activating factor 1 | 0.318 | ||
| CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.300 | Human | |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.241 | ||
| POU5F1 | POU class 5 homeobox 1 | 0.205 | ||
| CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.192 | ||
| CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.190 | Human | |
| NLRC4 | NLR family, CARD domain containing 4 | 0.174 | ||
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.160 | Human | |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.136 | ||
| FAS | Fas (TNF receptor superfamily, member 6) | 0.126 | ||
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.125 | ||
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.116 | ||
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.108 | ||
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.107 | ||
| IER3 | immediate early response 3 | 0.100 | ||
| DAXX | death-domain associated protein | 0.095 | ||
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.087 | ||
| CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.080 | ||
| BCL2 | B-cell CLL/lymphoma 2 | 0.077 | ||
| POU3F2 | POU class 3 homeobox 2 | 0.054 | ||
| FADD | Fas (TNFRSF6)-associated via death domain | 0.053 | ||
| SMAD7 | SMAD family member 7 | 0.050 | ||
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.046 | ||
| CDK2 | cyclin-dependent kinase 2 | 0.038 | ||
| NCL | nucleolin | 0.037 | ||
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.036 | ||
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.034 | ||
| EP300 | E1A binding protein p300 | 0.032 | ||
| CDK6 | cyclin-dependent kinase 6 | 0.032 | ||
| NOTCH1 | notch 1 | 0.030 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.029 | ||
| BIRC2 | baculoviral IAP repeat containing 2 | 0.028 | ||
| CCND1 | cyclin D1 | 0.025 | ||
| ATM | ataxia telangiectasia mutated | 0.024 | ||
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.021 | ||
| RBL2 | retinoblastoma-like 2 (p130) | 0.021 | ||
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.018 | Human | |
| IFI16 | interferon, gamma-inducible protein 16 | 0.017 | ||
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.016 | ||
| ELF4 | E74-like factor 4 (ets domain transcription factor) | 0.015 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.014 | ||
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.013 | Human | |
| MDFI | MyoD family inhibitor | 0.013 | ||
| CCND3 | cyclin D3 | 0.013 | ||
| NUCB2 | nucleobindin 2 | 0.012 | ||
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.012 | ||
| MARCKSL1 | MARCKS-like 1 | 0.010 | ||
| SALL2 | sal-like 2 (Drosophila) | 0.010 | ||
| CCNE1 | cyclin E1 | 0.010 |