IMP

Process View

Homo sapiens

3 genes annotated in human

negative regulation of protein deubiquitination

Any process that decreases the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of protein deubiquitination"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of protein deubiquitination" (in gray)

Name	Description	Probability	Func Analog Organism
MED15	mediator complex subunit 15	0.899
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.766
ZNF263	zinc finger protein 263	0.480
FAS	Fas (TNF receptor superfamily, member 6)	0.452
TRIM5	tripartite motif containing 5	0.386	Human
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.368
FADD	Fas (TNFRSF6)-associated via death domain	0.352
UBE2D4	ubiquitin-conjugating enzyme E2D 4 (putative)	0.309
DAXX	death-domain associated protein	0.302
IFI16	interferon, gamma-inducible protein 16	0.241
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.237
TRIM21	tripartite motif containing 21	0.211
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.144
SP100	SP100 nuclear antigen	0.104
ZNF473	zinc finger protein 473	0.093
MCOLN1	mucolipin 1	0.083
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.079
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.078
PML	promyelocytic leukemia	0.074
STIP1	stress-induced-phosphoprotein 1	0.071
BAG2	BCL2-associated athanogene 2	0.066
HSPA8	heat shock 70kDa protein 8	0.059
DDX60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.050
GBP2	guanylate binding protein 2, interferon-inducible	0.042
TRIM52	tripartite motif containing 52	0.042
TRIM35	tripartite motif containing 35	0.041
UBE2U	ubiquitin-conjugating enzyme E2U (putative)	0.039
PSEN2	presenilin 2 (Alzheimer disease 4)	0.036
RNF5	ring finger protein 5	0.035
NMI	N-myc (and STAT) interactor	0.034
TRIM34	tripartite motif containing 34	0.033
TRIM8	tripartite motif containing 8	0.031
TRIM6-TRIM34	TRIM6-TRIM34 readthrough	0.030
CFLAR	CASP8 and FADD-like apoptosis regulator	0.030
XIAP	X-linked inhibitor of apoptosis	0.029
TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	0.028
IRF2	interferon regulatory factor 2	0.028
PLSCR1	phospholipid scramblase 1	0.026
BAG1	BCL2-associated athanogene	0.026
TRIM41	tripartite motif containing 41	0.025	Human
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.025
UBQLN1	ubiquilin 1	0.025
PSEN1	presenilin 1	0.024
ATXN3	ataxin 3	0.024
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.023
CTSO	cathepsin O	0.021
TRAF3	TNF receptor-associated factor 3	0.021
TRIM26	tripartite motif containing 26	0.020
MR1	major histocompatibility complex, class I-related	0.019
IFI44	interferon-induced protein 44	0.019
MAGEF1	melanoma antigen family F, 1	0.019
TMCO6	transmembrane and coiled-coil domains 6	0.018
NDUFA4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa	0.018
SREBF1	sterol regulatory element binding transcription factor 1	0.017
TRIM6	tripartite motif containing 6	0.017	Human
ANXA1	annexin A1	0.017
MAGEA1	melanoma antigen family A, 1 (directs expression of antigen MZ2-E)	0.017
PIK3C2B	phosphoinositide-3-kinase, class 2, beta polypeptide	0.017
ARIH2	ariadne homolog 2 (Drosophila)	0.017
ATP5J	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6	0.017
ZCCHC6	zinc finger, CCHC domain containing 6	0.016
TRADD	TNFRSF1A-associated via death domain	0.016
UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.016
ZBTB8A	zinc finger and BTB domain containing 8A	0.015
RIC8A	resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)	0.015
DAD1	defender against cell death 1	0.015
IL15	interleukin 15	0.015
DTX3L	deltex 3-like (Drosophila)	0.015
TRIM4	tripartite motif containing 4	0.015	Human
PLCD4	phospholipase C, delta 4	0.015
MKRN3	makorin ring finger protein 3	0.014
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	0.014
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.014
PHF11	PHD finger protein 11	0.014
ZNRF1	zinc and ring finger 1	0.014
BAG3	BCL2-associated athanogene 3	0.014
ELK1	ELK1, member of ETS oncogene family	0.014
TDRD7	tudor domain containing 7	0.014
RNF31	ring finger protein 31	0.014
OSBP2	oxysterol binding protein 2	0.013
UBTD1	ubiquitin domain containing 1	0.013
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.013
RNF166	ring finger protein 166	0.013
SDSL	serine dehydratase-like	0.013
TRIM32	tripartite motif containing 32	0.013
UBE2Z	ubiquitin-conjugating enzyme E2Z	0.013
MUL1	mitochondrial E3 ubiquitin protein ligase 1	0.012
RNF25	ring finger protein 25	0.012
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.012
E4F1	E4F transcription factor 1	0.012
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.012
ZNF202	zinc finger protein 202	0.012
HK2	hexokinase 2	0.012
KRT18	keratin 18	0.012
UBOX5	U-box domain containing 5	0.012
IFIT5	interferon-induced protein with tetratricopeptide repeats 5	0.012
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.011
TUBGCP4	tubulin, gamma complex associated protein 4	0.011
PRKCA	protein kinase C, alpha	0.011
HSPA1B	heat shock 70kDa protein 1B	0.011
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.011
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.010
HIPK2	homeodomain interacting protein kinase 2	0.010
RERE	arginine-glutamic acid dipeptide (RE) repeats	0.010
GBP3	guanylate binding protein 3	0.010
NLRC5	NLR family, CARD domain containing 5	0.010
TRIM39	tripartite motif containing 39	0.010	Human
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.010