IMP

Process View

Homo sapiens

24 genes annotated in human

Multi-species View

regulation of fatty acid metabolic process

GO:0019217

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of fatty acid metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of fatty acid metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
RARA	retinoic acid receptor, alpha	0.985
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.615	Yeast
APOA1	apolipoprotein A-I	0.606	Human
PEX19	peroxisomal biogenesis factor 19	0.491
ALB	albumin	0.481
INSR	insulin receptor	0.466
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.364	Rat
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.319
APOE	apolipoprotein E	0.191
SREBF2	sterol regulatory element binding transcription factor 2	0.191
PPARG	peroxisome proliferator-activated receptor gamma	0.176	Rat
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.157
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.141
GRB10	growth factor receptor-bound protein 10	0.140
HNF4A	hepatocyte nuclear factor 4, alpha	0.132	Rat Worm
SMAD3	SMAD family member 3	0.117
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.114	Yeast
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.112	Yeast
SETD8	SET domain containing (lysine methyltransferase) 8	0.102
ESRRG	estrogen-related receptor gamma	0.100
MAPT	microtubule-associated protein tau	0.098
NCOR2	nuclear receptor corepressor 2	0.098
CREBBP	CREB binding protein	0.093
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.088
NOXA1	NADPH oxidase activator 1	0.084
SMAD1	SMAD family member 1	0.078
MED15	mediator complex subunit 15	0.071
HP	haptoglobin	0.069
IGF1R	insulin-like growth factor 1 receptor	0.068
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.068
SGK3	serum/glucocorticoid regulated kinase family, member 3	0.065
SMAD7	SMAD family member 7	0.065
CYBA	cytochrome b-245, alpha polypeptide	0.054
SMAD4	SMAD family member 4	0.052
NCOR1	nuclear receptor corepressor 1	0.052
FGA	fibrinogen alpha chain	0.049
SMAD5	SMAD family member 5	0.049
IDI1	isopentenyl-diphosphate delta isomerase 1	0.047
ACAA1	acetyl-CoA acyltransferase 1	0.047
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.047
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.046	Yeast
SKIL	SKI-like oncogene	0.045
NCOA1	nuclear receptor coactivator 1	0.045
FBXL15	F-box and leucine-rich repeat protein 15	0.044
EDF1	endothelial differentiation-related factor 1	0.043
SUFU	suppressor of fused homolog (Drosophila)	0.041
IRS1	insulin receptor substrate 1	0.038
MAP2K4	mitogen-activated protein kinase kinase 4	0.037
APOA2	apolipoprotein A-II	0.037
APOC1	apolipoprotein C-I	0.036
ITGB1BP3	integrin beta 1 binding protein 3	0.032
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.030	Yeast
ATF5	activating transcription factor 5	0.030
NCF1	neutrophil cytosolic factor 1	0.030
SMAD2	SMAD family member 2	0.029
APOC3	apolipoprotein C-III	0.029
GATA2	GATA binding protein 2	0.027
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.027	Yeast
UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3	0.026
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.026
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.025
PGRMC1	progesterone receptor membrane component 1	0.025
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.025
POU5F1	POU class 5 homeobox 1	0.025
ANKRD13A	ankyrin repeat domain 13A	0.024
ECH1	enoyl CoA hydratase 1, peroxisomal	0.023
A2M	alpha-2-macroglobulin	0.023
ETFB	electron-transfer-flavoprotein, beta polypeptide	0.023
DOCK7	dedicator of cytokinesis 7	0.022
MED25	mediator complex subunit 25	0.020
CCL14	chemokine (C-C motif) ligand 14	0.020
KAT2B	K(lysine) acetyltransferase 2B	0.020
ZFYVE9	zinc finger, FYVE domain containing 9	0.020
AR	androgen receptor	0.020
LCAT	lecithin-cholesterol acyltransferase	0.020
RICTOR	RPTOR independent companion of MTOR, complex 2	0.019
SMAD6	SMAD family member 6	0.019
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.019
MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	0.018
RUNX1	runt-related transcription factor 1	0.018
EGFR	epidermal growth factor receptor	0.018
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.018
TRAF4	TNF receptor-associated factor 4	0.017
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.017
SPOP	speckle-type POZ protein	0.017
SNCAIP	synuclein, alpha interacting protein	0.017
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.017
OPTN	optineurin	0.016
GSK3B	glycogen synthase kinase 3 beta	0.016
RNF123	ring finger protein 123	0.016
MYOD1	myogenic differentiation 1	0.016
SH3RF1	SH3 domain containing ring finger 1	0.016
TF	transferrin	0.016
HTT	huntingtin	0.016
PTEN	phosphatase and tensin homolog	0.016
TCF12	transcription factor 12	0.016
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.016	Yeast
LAT	linker for activation of T cells	0.015
HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase	0.015
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.015
XPO7	exportin 7	0.015
PROX1	prospero homeobox 1	0.015
APOB	apolipoprotein B (including Ag(x) antigen)	0.015
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.015
TAL1	T-cell acute lymphocytic leukemia 1	0.014	Human
MSTO1	misato homolog 1 (Drosophila)	0.014
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.014	Rat
PDPK1	3-phosphoinositide dependent protein kinase-1	0.014
FOXO1	forkhead box O1	0.014
PRKCA	protein kinase C, alpha	0.014
GLI1	GLI family zinc finger 1	0.014
TSC22D1	TSC22 domain family, member 1	0.014
HOXD12	homeobox D12	0.013
GATA4	GATA binding protein 4	0.013
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.013
SCD	stearoyl-CoA desaturase (delta-9-desaturase)	0.013
ACVR1B	activin A receptor, type IB	0.013
PTPN5	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)	0.013
LDLR	low density lipoprotein receptor	0.013
PRKCZ	protein kinase C, zeta	0.013	Human
PDX1	pancreatic and duodenal homeobox 1	0.012
NR1H3	nuclear receptor subfamily 1, group H, member 3	0.012
MAPK8	mitogen-activated protein kinase 8	0.012
FRS2	fibroblast growth factor receptor substrate 2	0.012
C12orf44	chromosome 12 open reading frame 44	0.012
PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	0.012
PRKCB	protein kinase C, beta	0.012
IRS2	insulin receptor substrate 2	0.012
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.012
FOXD3	forkhead box D3	0.012
ACACA	acetyl-CoA carboxylase alpha	0.012
ZER1	zer-1 homolog (C. elegans)	0.012
EPAS1	endothelial PAS domain protein 1	0.011
IGF2R	insulin-like growth factor 2 receptor	0.011
CXXC5	CXXC finger protein 5	0.011
ZNF71	zinc finger protein 71	0.011
TTR	transthyretin	0.011
HDAC5	histone deacetylase 5	0.011
MED12	mediator complex subunit 12	0.011
RPTOR	regulatory associated protein of MTOR, complex 1	0.011
CALCOCO1	calcium binding and coiled-coil domain 1	0.011
AHSG	alpha-2-HS-glycoprotein	0.011
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.011
STX5	syntaxin 5	0.011
TPPP	tubulin polymerization promoting protein	0.011
GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	0.011
PICK1	protein interacting with PRKCA 1	0.011
FAM46A	family with sequence similarity 46, member A	0.011
DHCR7	7-dehydrocholesterol reductase	0.010
DDA1	DET1 and DDB1 associated 1	0.010
PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	0.010
DEPTOR	DEP domain containing MTOR-interacting protein	0.010
POR	P450 (cytochrome) oxidoreductase	0.010
F2	coagulation factor II (thrombin)	0.010
RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1	0.010
ING2	inhibitor of growth family, member 2	0.010
PGK1	phosphoglycerate kinase 1	0.010
SOX7	SRY (sex determining region Y)-box 7	0.010
AGL	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	0.010