IMP
Process View
negative regulation of tumor necrosis factor production
Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.
Loading network...
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of tumor necrosis factor production"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.999 | Human | |
| MYD88 | myeloid differentiation primary response gene (88) | 0.998 | ||
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.933 | ||
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.923 | Human | |
| TRAF6 | TNF receptor-associated factor 6 | 0.816 | ||
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.813 | ||
| LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 | 0.639 | ||
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 | 0.634 | ||
| C1QA | complement component 1, q subcomponent, A chain | 0.500 | Human | |
| PILRA | paired immunoglobin-like type 2 receptor alpha | 0.487 | ||
| GAS6 | growth arrest-specific 6 | 0.428 | ||
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.427 | ||
| MED15 | mediator complex subunit 15 | 0.359 | ||
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 | 0.349 | Human | |
| C1QB | complement component 1, q subcomponent, B chain | 0.346 | Human | |
| PELI3 | pellino homolog 3 (Drosophila) | 0.261 | ||
| RNF126 | ring finger protein 126 | 0.260 | ||
| UBE2D4 | ubiquitin-conjugating enzyme E2D 4 (putative) | 0.223 | ||
| AXL | AXL receptor tyrosine kinase | 0.215 | Mouse | |
| CD14 | CD14 molecule | 0.195 | ||
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 | 0.191 | Human | |
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.169 | ||
| SETD8 | SET domain containing (lysine methyltransferase) 8 | 0.168 | ||
| ZNF263 | zinc finger protein 263 | 0.099 | ||
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.084 | ||
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 | 0.078 | Human | |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.076 | ||
| SPOP | speckle-type POZ protein | 0.074 | ||
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 | 0.066 | ||
| APOE | apolipoprotein E | 0.056 | ||
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.055 | Human | |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.048 | ||
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.048 | ||
| RARA | retinoic acid receptor, alpha | 0.046 | ||
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.043 | ||
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.041 | ||
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.040 | ||
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.039 | ||
| TRIM5 | tripartite motif containing 5 | 0.037 | Human Mouse | |
| TNIP2 | TNFAIP3 interacting protein 2 | 0.037 | ||
| TRIM39 | tripartite motif containing 39 | 0.036 | Human | |
| PTAFR | platelet-activating factor receptor | 0.036 | ||
| CD163 | CD163 molecule | 0.035 | ||
| IRAK4 | interleukin-1 receptor-associated kinase 4 | 0.034 | ||
| TRIM26 | tripartite motif containing 26 | 0.032 | ||
| TICAM2 | toll-like receptor adaptor molecule 2 | 0.032 | ||
| IL10RA | interleukin 10 receptor, alpha | 0.032 | ||
| TOLLIP | toll interacting protein | 0.030 | ||
| SIGLEC7 | sialic acid binding Ig-like lectin 7 | 0.029 | ||
| IRF7 | interferon regulatory factor 7 | 0.029 | ||
| TRIM21 | tripartite motif containing 21 | 0.029 | Human | |
| HK3 | hexokinase 3 (white cell) | 0.026 | ||
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.026 | ||
| TNIP1 | TNFAIP3 interacting protein 1 | 0.026 | ||
| MARCO | macrophage receptor with collagenous structure | 0.025 | ||
| SP110 | SP110 nuclear body protein | 0.024 | ||
| CSK | c-src tyrosine kinase | 0.024 | ||
| BAG3 | BCL2-associated athanogene 3 | 0.023 | ||
| RXRA | retinoid X receptor, alpha | 0.022 | ||
| RNF5 | ring finger protein 5 | 0.022 | ||
| IKZF3 | IKAROS family zinc finger 3 (Aiolos) | 0.021 | ||
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.021 | ||
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | 0.021 | ||
| MSR1 | macrophage scavenger receptor 1 | 0.021 | ||
| TLR2 | toll-like receptor 2 | 0.020 | ||
| ZNF473 | zinc finger protein 473 | 0.020 | ||
| RNF11 | ring finger protein 11 | 0.020 | ||
| BIRC3 | baculoviral IAP repeat containing 3 | 0.019 | ||
| APOA1 | apolipoprotein A-I | 0.019 | ||
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4 | 0.019 | ||
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) | 0.018 | ||
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.018 | ||
| TLR7 | toll-like receptor 7 | 0.018 | ||
| TRIM17 | tripartite motif containing 17 | 0.018 | Human | |
| SLAMF8 | SLAM family member 8 | 0.017 | ||
| TRIM34 | tripartite motif containing 34 | 0.017 | ||
| SBNO2 | strawberry notch homolog 2 (Drosophila) | 0.017 | ||
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.017 | ||
| AIF1 | allograft inflammatory factor 1 | 0.017 | ||
| TICAM1 | toll-like receptor adaptor molecule 1 | 0.017 | ||
| C1QC | complement component 1, q subcomponent, C chain | 0.017 | Human | |
| PML | promyelocytic leukemia | 0.016 | ||
| C1S | complement component 1, s subcomponent | 0.016 | ||
| ITGB1BP2 | integrin beta 1 binding protein (melusin) 2 | 0.016 | ||
| PPARA | peroxisome proliferator-activated receptor alpha | 0.016 | ||
| AOAH | acyloxyacyl hydrolase (neutrophil) | 0.016 | ||
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.015 | ||
| CCR1 | chemokine (C-C motif) receptor 1 | 0.015 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.014 | ||
| TYMP | thymidine phosphorylase | 0.014 | ||
| XIAP | X-linked inhibitor of apoptosis | 0.014 | ||
| BCL10 | B-cell CLL/lymphoma 10 | 0.014 | ||
| SP100 | SP100 nuclear antigen | 0.014 | ||
| NCOA1 | nuclear receptor coactivator 1 | 0.014 | ||
| CMKLR1 | chemokine-like receptor 1 | 0.014 | ||
| STAB1 | stabilin 1 | 0.014 | ||
| MED25 | mediator complex subunit 25 | 0.014 | ||
| CHRNA1 | cholinergic receptor, nicotinic, alpha 1 (muscle) | 0.013 | Human | |
| HP | haptoglobin | 0.013 | ||
| SLC15A3 | solute carrier family 15, member 3 | 0.013 | ||
| TRIM43 | tripartite motif containing 43 | 0.013 | ||
| TMEM176A | transmembrane protein 176A | 0.013 | ||
| C5orf41 | chromosome 5 open reading frame 41 | 0.012 | ||
| IGSF6 | immunoglobulin superfamily, member 6 | 0.012 | ||
| KLHL24 | kelch-like 24 (Drosophila) | 0.012 | ||
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.012 | ||
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.012 | ||
| CARD11 | caspase recruitment domain family, member 11 | 0.012 | ||
| HDAC9 | histone deacetylase 9 | 0.012 | ||
| PELI1 | pellino homolog 1 (Drosophila) | 0.012 | ||
| NLRP3 | NLR family, pyrin domain containing 3 | 0.012 | ||
| IL1R1 | interleukin 1 receptor, type I | 0.011 | ||
| CFL1 | cofilin 1 (non-muscle) | 0.011 | ||
| USP4 | ubiquitin specific peptidase 4 (proto-oncogene) | 0.011 | ||
| TLR4 | toll-like receptor 4 | 0.011 | Mouse | |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.011 | ||
| UBE2U | ubiquitin-conjugating enzyme E2U (putative) | 0.011 | ||
| C2orf18 | chromosome 2 open reading frame 18 | 0.011 | ||
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.011 | ||
| C1R | complement component 1, r subcomponent | 0.011 | ||
| SAMD9 | sterile alpha motif domain containing 9 | 0.011 | ||
| EGR2 | early growth response 2 | 0.011 | ||
| A2M | alpha-2-macroglobulin | 0.011 | ||
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 0.011 | ||
| LILRA3 | leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 | 0.010 | Human | |
| CTSO | cathepsin O | 0.010 | ||
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic | 0.010 | ||
| RXRG | retinoid X receptor, gamma | 0.010 | ||
| MCOLN1 | mucolipin 1 | 0.010 | ||
| C3AR1 | complement component 3a receptor 1 | 0.010 | ||
| RNASE3 | ribonuclease, RNase A family, 3 | 0.010 | ||
| MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.010 | ||
| CD68 | CD68 molecule | 0.010 |