IMP
Process View
cellular response to misfolded protein
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to misfolded protein"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| VCP | valosin containing protein | 1.000 | Yeast Worm | |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.996 | Yeast | |
| NSFL1C | NSFL1 (p97) cofactor (p47) | 0.977 | ||
| HSPA1B | heat shock 70kDa protein 1B | 0.751 | ||
| UBE4B | ubiquitination factor E4B (UFD2 homolog, yeast) | 0.678 | ||
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.550 | ||
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 | 0.550 | ||
| AMFR | autocrine motility factor receptor | 0.528 | ||
| BAG1 | BCL2-associated athanogene | 0.506 | ||
| BAG3 | BCL2-associated athanogene 3 | 0.498 | ||
| UBXN2A | UBX domain protein 2A | 0.453 | ||
| SELS | selenoprotein S | 0.419 | ||
| XIAP | X-linked inhibitor of apoptosis | 0.402 | ||
| HSPA1A | heat shock 70kDa protein 1A | 0.173 | ||
| ATXN3 | ataxin 3 | 0.171 | Mouse | |
| ADRBK1 | adrenergic, beta, receptor kinase 1 | 0.141 | ||
| SYVN1 | synovial apoptosis inhibitor 1, synoviolin | 0.137 | ||
| HSF1 | heat shock transcription factor 1 | 0.118 | ||
| FAF2 | Fas associated factor family member 2 | 0.097 | ||
| UBXN1 | UBX domain protein 1 | 0.092 | ||
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) | 0.090 | ||
| ZNRF1 | zinc and ring finger 1 | 0.077 | ||
| UBXN6 | UBX domain protein 6 | 0.072 | ||
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.070 | ||
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast) | 0.055 | ||
| CDC37 | cell division cycle 37 homolog (S. cerevisiae) | 0.055 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.047 | ||
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.045 | ||
| HSPB1 | heat shock 27kDa protein 1 | 0.045 | ||
| CYLD | cylindromatosis (turban tumor syndrome) | 0.044 | ||
| UBL4A | ubiquitin-like 4A | 0.042 | ||
| TRAF6 | TNF receptor-associated factor 6 | 0.035 | ||
| RNF111 | ring finger protein 111 | 0.035 | ||
| ATP13A2 | ATPase type 13A2 | 0.031 | ||
| RNF14 | ring finger protein 14 | 0.031 | ||
| MBNL2 | muscleblind-like 2 (Drosophila) | 0.031 | ||
| PRKCA | protein kinase C, alpha | 0.030 | ||
| CTTN | cortactin | 0.030 | ||
| MKRN1 | makorin ring finger protein 1 | 0.029 | ||
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 | 0.028 | ||
| ABHD16A | abhydrolase domain containing 16A | 0.028 | ||
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast) | 0.027 | ||
| NGLY1 | N-glycanase 1 | 0.027 | ||
| SNX1 | sorting nexin 1 | 0.026 | ||
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.026 | ||
| SNX16 | sorting nexin 16 | 0.025 | ||
| BAG2 | BCL2-associated athanogene 2 | 0.025 | ||
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.024 | ||
| UBE2Q1 | ubiquitin-conjugating enzyme E2Q family member 1 | 0.023 | ||
| ZRANB1 | zinc finger, RAN-binding domain containing 1 | 0.023 | ||
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.023 | Yeast | |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.021 | ||
| FHOD1 | formin homology 2 domain containing 1 | 0.020 | ||
| SURF2 | surfeit 2 | 0.020 | ||
| C16orf70 | chromosome 16 open reading frame 70 | 0.019 | ||
| TUBA1C | tubulin, alpha 1c | 0.019 | ||
| SIRT2 | sirtuin 2 | 0.018 | ||
| BFAR | bifunctional apoptosis regulator | 0.018 | ||
| PJA2 | praja ring finger 2 | 0.018 | ||
| RNF2 | ring finger protein 2 | 0.017 | ||
| ZNF654 | zinc finger protein 654 | 0.016 | ||
| HSPA2 | heat shock 70kDa protein 2 | 0.015 | ||
| PILRB | paired immunoglobin-like type 2 receptor beta | 0.015 | ||
| WBSCR22 | Williams Beuren syndrome chromosome region 22 | 0.015 | ||
| SIK2 | salt-inducible kinase 2 | 0.014 | ||
| ZMYM3 | zinc finger, MYM-type 3 | 0.014 | ||
| MIB1 | mindbomb homolog 1 (Drosophila) | 0.014 | ||
| PPHLN1 | periphilin 1 | 0.013 | ||
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.013 | ||
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.012 | ||
| PXN | paxillin | 0.012 | ||
| FKBP8 | FK506 binding protein 8, 38kDa | 0.012 | ||
| RGS2 | regulator of G-protein signaling 2, 24kDa | 0.012 | ||
| TRIM39 | tripartite motif containing 39 | 0.011 | ||
| HSPB8 | heat shock 22kDa protein 8 | 0.011 | ||
| TRIM23 | tripartite motif containing 23 | 0.011 | ||
| MFN2 | mitofusin 2 | 0.011 | ||
| FCHSD2 | FCH and double SH3 domains 2 | 0.011 | ||
| TOMM34 | translocase of outer mitochondrial membrane 34 | 0.010 | ||
| RNF10 | ring finger protein 10 | 0.010 | ||
| DZIP3 | DAZ interacting protein 3, zinc finger | 0.010 | ||
| UFD1L | ubiquitin fusion degradation 1 like (yeast) | 0.010 | Worm |