IMP
Process View
hepaticobiliary system development
The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "hepaticobiliary system development"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| JAG1 | jagged 1 | 0.601 | Zebrafish | |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.550 | ||
| HNF4A | hepatocyte nuclear factor 4, alpha | 0.384 | ||
| CCND1 | cyclin D1 | 0.381 | Rat | |
| NOTCH1 | notch 1 | 0.356 | Mouse | |
| NCOA1 | nuclear receptor coactivator 1 | 0.350 | ||
| E2F7 | E2F transcription factor 7 | 0.319 | Mouse | |
| NOTCH3 | notch 3 | 0.261 | Zebrafish | |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.234 | ||
| CCND3 | cyclin D3 | 0.232 | ||
| E2F8 | E2F transcription factor 8 | 0.178 | Mouse | |
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.164 | ||
| EP300 | E1A binding protein p300 | 0.162 | ||
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.157 | ||
| HDAC2 | histone deacetylase 2 | 0.137 | ||
| CDK6 | cyclin-dependent kinase 6 | 0.127 | ||
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.125 | ||
| RUNX1 | runt-related transcription factor 1 | 0.105 | Mouse | |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.101 | ||
| CDK2 | cyclin-dependent kinase 2 | 0.089 | ||
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.081 | ||
| SIRT1 | sirtuin 1 | 0.078 | ||
| CCNE1 | cyclin E1 | 0.069 | Rat | |
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.066 | ||
| PKD2 | polycystic kidney disease 2 (autosomal dominant) | 0.065 | ||
| IARS | isoleucyl-tRNA synthetase | 0.064 | ||
| FGF1 | fibroblast growth factor 1 (acidic) | 0.059 | ||
| SETD7 | SET domain containing (lysine methyltransferase) 7 | 0.058 | ||
| MED25 | mediator complex subunit 25 | 0.057 | ||
| CDK19 | cyclin-dependent kinase 19 | 0.051 | ||
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.045 | ||
| ARNT | aryl hydrocarbon receptor nuclear translocator | 0.041 | ||
| BBS10 | Bardet-Biedl syndrome 10 | 0.039 | ||
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.039 | ||
| BBS1 | Bardet-Biedl syndrome 1 | 0.038 | ||
| ATF3 | activating transcription factor 3 | 0.036 | ||
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa | 0.035 | ||
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.034 | ||
| NR0B2 | nuclear receptor subfamily 0, group B, member 2 | 0.033 | ||
| KLF4 | Kruppel-like factor 4 (gut) | 0.031 | ||
| NCK2 | NCK adaptor protein 2 | 0.029 | ||
| GHR | growth hormone receptor | 0.029 | ||
| MED13L | mediator complex subunit 13-like | 0.027 | ||
| TP53 | tumor protein p53 | 0.025 | ||
| NOTCH2 | notch 2 | 0.025 | Zebrafish | |
| MAFA | v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) | 0.025 | ||
| TNIP2 | TNFAIP3 interacting protein 2 | 0.024 | ||
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.024 | ||
| ACAA2 | acetyl-CoA acyltransferase 2 | 0.024 | ||
| GET4 | golgi to ER traffic protein 4 homolog (S. cerevisiae) | 0.023 | ||
| CSNK1E | casein kinase 1, epsilon | 0.022 | ||
| PKD1 | polycystic kidney disease 1 (autosomal dominant) | 0.022 | Mouse | |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.022 | ||
| NRIP1 | nuclear receptor interacting protein 1 | 0.021 | ||
| RXRA | retinoid X receptor, alpha | 0.021 | Rat | |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.021 | ||
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.020 | ||
| NCOA6 | nuclear receptor coactivator 6 | 0.020 | ||
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.019 | ||
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.019 | Rat | |
| NCOR2 | nuclear receptor corepressor 2 | 0.019 | ||
| PML | promyelocytic leukemia | 0.018 | ||
| SP3 | Sp3 transcription factor | 0.017 | Mouse | |
| ARRB1 | arrestin, beta 1 | 0.017 | ||
| RARA | retinoic acid receptor, alpha | 0.017 | Zebrafish Rat | |
| MED13 | mediator complex subunit 13 | 0.017 | ||
| SUZ12 | suppressor of zeste 12 homolog (Drosophila) | 0.017 | ||
| EZH2 | enhancer of zeste homolog 2 (Drosophila) | 0.017 | ||
| HADH | hydroxyacyl-CoA dehydrogenase | 0.016 | ||
| TGIF1 | TGFB-induced factor homeobox 1 | 0.016 | ||
| GARS | glycyl-tRNA synthetase | 0.016 | ||
| DUSP1 | dual specificity phosphatase 1 | 0.016 | ||
| PCGF2 | polycomb group ring finger 2 | 0.016 | ||
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.016 | Zebrafish | |
| STAG2 | stromal antigen 2 | 0.015 | ||
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.015 | ||
| NCOA3 | nuclear receptor coactivator 3 | 0.015 | ||
| VAC14 | Vac14 homolog (S. cerevisiae) | 0.015 | ||
| SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.014 | ||
| AGXT2 | alanine--glyoxylate aminotransferase 2 | 0.014 | ||
| VEZF1 | vascular endothelial zinc finger 1 | 0.014 | ||
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.014 | Rat | |
| FSTL1 | follistatin-like 1 | 0.013 | ||
| HNF1B | HNF1 homeobox B | 0.013 | Zebrafish Mouse | |
| DLL1 | delta-like 1 (Drosophila) | 0.013 | Zebrafish | |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.013 | ||
| ADAMTS10 | ADAM metallopeptidase with thrombospondin type 1 motif, 10 | 0.013 | ||
| EGFR | epidermal growth factor receptor | 0.013 | ||
| PDX1 | pancreatic and duodenal homeobox 1 | 0.012 | Zebrafish Mouse | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.012 | ||
| JUN | jun proto-oncogene | 0.012 | Mouse | |
| FOXA2 | forkhead box A2 | 0.012 | ||
| APOE | apolipoprotein E | 0.012 | ||
| RB1 | retinoblastoma 1 | 0.012 | ||
| ERBB2IP | erbb2 interacting protein | 0.011 | ||
| SMAD1 | SMAD family member 1 | 0.011 | ||
| HR | hairless homolog (mouse) | 0.011 | ||
| FGF2 | fibroblast growth factor 2 (basic) | 0.011 | ||
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) | 0.011 | ||
| MAML1 | mastermind-like 1 (Drosophila) | 0.011 |