IMP

Process View

Homo sapiens

1 genes annotated in human

negative regulation of testicular blood vessel morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis in the testicle.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of testicular blood vessel morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of testicular blood vessel morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
FGF18	fibroblast growth factor 18	0.988
WNT1	wingless-type MMTV integration site family, member 1	0.936	Human
WIF1	WNT inhibitory factor 1	0.828
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.699
AQP5	aquaporin 5	0.571
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.487
IHH	Indian hedgehog	0.478
WNT3	wingless-type MMTV integration site family, member 3	0.454	Human
LBX1	ladybird homeobox 1	0.447
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.427
HES2	hairy and enhancer of split 2 (Drosophila)	0.373
WNT10A	wingless-type MMTV integration site family, member 10A	0.342	Human
FGF8	fibroblast growth factor 8 (androgen-induced)	0.303
SFRP1	secreted frizzled-related protein 1	0.274
WNT6	wingless-type MMTV integration site family, member 6	0.268	Human
FGF3	fibroblast growth factor 3	0.204
FOXL1	forkhead box L1	0.188
COL6A1	collagen, type VI, alpha 1	0.187
FGF4	fibroblast growth factor 4	0.171
FOXD3	forkhead box D3	0.163
WNT4	wingless-type MMTV integration site family, member 4	0.156
SOX21	SRY (sex determining region Y)-box 21	0.156
FOXF2	forkhead box F2	0.124
HMX1	H6 family homeobox 1	0.119
ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	0.117
WNT7A	wingless-type MMTV integration site family, member 7A	0.117	Human
DLX4	distal-less homeobox 4	0.114
NPAS1	neuronal PAS domain protein 1	0.109
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.108
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.105
PAX8	paired box 8	0.105
KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5	0.105
SOX1	SRY (sex determining region Y)-box 1	0.105
DUOX1	dual oxidase 1	0.102
VSX1	visual system homeobox 1	0.099
CRLF1	cytokine receptor-like factor 1	0.099
SHH	sonic hedgehog	0.098
HOXC8	homeobox C8	0.097
WNT10B	wingless-type MMTV integration site family, member 10B	0.085	Human
BHLHE23	basic helix-loop-helix family, member e23	0.084
FOXB1	forkhead box B1	0.083
POU3F1	POU class 3 homeobox 1	0.083
PAX7	paired box 7	0.080
NXPH4	neurexophilin 4	0.077
FZD8	frizzled homolog 8 (Drosophila)	0.077
PRRX2	paired related homeobox 2	0.076
HOXB8	homeobox B8	0.076
P2RX2	purinergic receptor P2X, ligand-gated ion channel, 2	0.072
TLX3	T-cell leukemia homeobox 3	0.072
WNT11	wingless-type MMTV integration site family, member 11	0.069	Human
RAX	retina and anterior neural fold homeobox	0.068
BMP4	bone morphogenetic protein 4	0.067
BMP8A	bone morphogenetic protein 8a	0.067
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.067
HOXD13	homeobox D13	0.065
NKD1	naked cuticle homolog 1 (Drosophila)	0.064
CDX2	caudal type homeobox 2	0.061
SFRP5	secreted frizzled-related protein 5	0.059
HS3ST6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6	0.059
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.057
HOXD9	homeobox D9	0.057
GUCA2A	guanylate cyclase activator 2A (guanylin)	0.054
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.053
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.053
PLXDC1	plexin domain containing 1	0.052
FSCN2	fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)	0.052
GDNF	glial cell derived neurotrophic factor	0.051
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.051
SLC18A3	solute carrier family 18 (vesicular acetylcholine), member 3	0.051
PITX1	paired-like homeodomain 1	0.051
RHBG	Rh family, B glycoprotein (gene/pseudogene)	0.050
HOXA11	homeobox A11	0.047
NKD2	naked cuticle homolog 2 (Drosophila)	0.046
CDX1	caudal type homeobox 1	0.045
ICOSLG	inducible T-cell co-stimulator ligand	0.044
FIBCD1	fibrinogen C domain containing 1	0.042
HOXD11	homeobox D11	0.041
EPHB2	EPH receptor B2	0.040
NPPC	natriuretic peptide C	0.040
SPIB	Spi-B transcription factor (Spi-1/PU.1 related)	0.039
GRIN2D	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.038
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.036
WNT7B	wingless-type MMTV integration site family, member 7B	0.036	Human
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.036
CDHR1	cadherin-related family member 1	0.036
COL2A1	collagen, type II, alpha 1	0.034
JPH3	junctophilin 3	0.034
SIX2	SIX homeobox 2	0.034
EPHB3	EPH receptor B3	0.034
KCNK9	potassium channel, subfamily K, member 9	0.034
TNK1	tyrosine kinase, non-receptor, 1	0.033
S1PR5	sphingosine-1-phosphate receptor 5	0.033
HCRTR1	hypocretin (orexin) receptor 1	0.033
HES5	hairy and enhancer of split 5 (Drosophila)	0.032
SULT2B1	sulfotransferase family, cytosolic, 2B, member 1	0.031
NEUROG2	neurogenin 2	0.030
GGN	gametogenetin	0.030
MGAT5B	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B	0.030
NKX3-2	NK3 homeobox 2	0.029
HOXD10	homeobox D10	0.029
CCDC48	coiled-coil domain containing 48	0.029
HSD11B2	hydroxysteroid (11-beta) dehydrogenase 2	0.029
SCARF2	scavenger receptor class F, member 2	0.028
DRD4	dopamine receptor D4	0.028
EVPL	envoplakin	0.028
NKPD1	NTPase, KAP family P-loop domain containing 1	0.027
NGF	nerve growth factor (beta polypeptide)	0.027
COL13A1	collagen, type XIII, alpha 1	0.027
GBX2	gastrulation brain homeobox 2	0.027
HOXB1	homeobox B1	0.027
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.027
WNT2B	wingless-type MMTV integration site family, member 2B	0.027	Human
EFNA3	ephrin-A3	0.026
KREMEN2	kringle containing transmembrane protein 2	0.026
USH1G	Usher syndrome 1G (autosomal recessive)	0.026
LHX3	LIM homeobox 3	0.026
GSC	goosecoid homeobox	0.026
HOXC12	homeobox C12	0.026
DIO3	deiodinase, iodothyronine, type III	0.026
TKTL1	transketolase-like 1	0.026
ESPN	espin	0.025
ALX4	ALX homeobox 4	0.025
ADRA1D	adrenergic, alpha-1D-, receptor	0.025
FEZF2	FEZ family zinc finger 2	0.024
CTF1	cardiotrophin 1	0.024
A4GALT	alpha 1,4-galactosyltransferase	0.024
TFAP2D	transcription factor AP-2 delta (activating enhancer binding protein 2 delta)	0.024
RARG	retinoic acid receptor, gamma	0.023
CRHR1	corticotropin releasing hormone receptor 1	0.023
MXRA5	matrix-remodelling associated 5	0.023
PAX3	paired box 3	0.023
KCNK15	potassium channel, subfamily K, member 15	0.023
HOXB13	homeobox B13	0.023
COL10A1	collagen, type X, alpha 1	0.022
SLC6A4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.022
GATA5	GATA binding protein 5	0.022
CYP11B2	cytochrome P450, family 11, subfamily B, polypeptide 2	0.022
WNT9B	wingless-type MMTV integration site family, member 9B	0.021	Human
HIC1	hypermethylated in cancer 1	0.021
TBX5	T-box 5	0.021
VSTM2L	V-set and transmembrane domain containing 2 like	0.021
ISLR2	immunoglobulin superfamily containing leucine-rich repeat 2	0.021
SIX5	SIX homeobox 5	0.021
ALOX12B	arachidonate 12-lipoxygenase, 12R type	0.021
KCNC3	potassium voltage-gated channel, Shaw-related subfamily, member 3	0.021
GSC2	goosecoid homeobox 2	0.021
IL11	interleukin 11	0.020
MMP19	matrix metallopeptidase 19	0.020
TBX1	T-box 1	0.020
ADRB3	adrenergic, beta-3-, receptor	0.020
RGS9BP	regulator of G protein signaling 9 binding protein	0.020
AIPL1	aryl hydrocarbon receptor interacting protein-like 1	0.020
ACAN	aggrecan	0.020
EGFL6	EGF-like-domain, multiple 6	0.020
ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)	0.020
EN1	engrailed homeobox 1	0.020
NKX2-1	NK2 homeobox 1	0.019
WNT5B	wingless-type MMTV integration site family, member 5B	0.019	Human
MMP13	matrix metallopeptidase 13 (collagenase 3)	0.019
HYAL1	hyaluronoglucosaminidase 1	0.019
OCA2	oculocutaneous albinism II	0.019
POU4F3	POU class 4 homeobox 3	0.019
TG	thyroglobulin	0.019
FZD10	frizzled homolog 10 (Drosophila)	0.019
SLC30A2	solute carrier family 30 (zinc transporter), member 2	0.019
EMX2	empty spiracles homeobox 2	0.019
GDF10	growth differentiation factor 10	0.019
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.019
MNX1	motor neuron and pancreas homeobox 1	0.019
NANOS3	nanos homolog 3 (Drosophila)	0.019
WSCD2	WSC domain containing 2	0.019
RSPO4	R-spondin family, member 4	0.018
IRX4	iroquois homeobox 4	0.018
ADAMTSL2	ADAMTS-like 2	0.018
CD70	CD70 molecule	0.018
KCNS2	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2	0.018
SLC29A4	solute carrier family 29 (nucleoside transporters), member 4	0.018
GLI2	GLI family zinc finger 2	0.018
PITX2	paired-like homeodomain 2	0.018
KNDC1	kinase non-catalytic C-lobe domain (KIND) containing 1	0.018
HAND2	heart and neural crest derivatives expressed 2	0.018
PRDM8	PR domain containing 8	0.018
PTH2	parathyroid hormone 2	0.018
SIM1	single-minded homolog 1 (Drosophila)	0.018
INSL3	insulin-like 3 (Leydig cell)	0.017
LYPD4	LY6/PLAUR domain containing 4	0.017
CHRD	chordin	0.017
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.017
PRPH	peripherin	0.017
RSPO1	R-spondin homolog (Xenopus laevis)	0.017
TLX1	T-cell leukemia homeobox 1	0.017
OLIG2	oligodendrocyte lineage transcription factor 2	0.017
REG1B	regenerating islet-derived 1 beta	0.017
BNC1	basonuclin 1	0.017
COL27A1	collagen, type XXVII, alpha 1	0.017
DLX2	distal-less homeobox 2	0.017
CRABP2	cellular retinoic acid binding protein 2	0.016
HTR1A	5-hydroxytryptamine (serotonin) receptor 1A	0.016
KCNK12	potassium channel, subfamily K, member 12	0.016
GPR20	G protein-coupled receptor 20	0.016
PYY	peptide YY	0.016
HR	hairless homolog (mouse)	0.016
GUCY1A2	guanylate cyclase 1, soluble, alpha 2	0.016
MIXL1	Mix1 homeobox-like 1 (Xenopus laevis)	0.016
GJA3	gap junction protein, alpha 3, 46kDa	0.016
CUX2	cut-like homeobox 2	0.016
SMTNL2	smoothelin-like 2	0.016
FOXF1	forkhead box F1	0.016
SLC9A3	solute carrier family 9 (sodium/hydrogen exchanger), member 3	0.016
HOXD4	homeobox D4	0.016
HOXD1	homeobox D1	0.016
KLK10	kallikrein-related peptidase 10	0.015
BFSP1	beaded filament structural protein 1, filensin	0.015
GPR123	G protein-coupled receptor 123	0.015
FGD1	FYVE, RhoGEF and PH domain containing 1	0.015
DNAJC22	DnaJ (Hsp40) homolog, subfamily C, member 22	0.015
LMO1	LIM domain only 1 (rhombotin 1)	0.015
DLL4	delta-like 4 (Drosophila)	0.015
BMP7	bone morphogenetic protein 7	0.015
AVPR1B	arginine vasopressin receptor 1B	0.015
DUOX2	dual oxidase 2	0.015
HOXC5	homeobox C5	0.015
CAPN6	calpain 6	0.015
FOXL2	forkhead box L2	0.015
NOTCH3	notch 3	0.015
PRMT8	protein arginine methyltransferase 8	0.015
HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.015
HOXC11	homeobox C11	0.015
LTK	leukocyte receptor tyrosine kinase	0.015
CDK5R2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.015
SMO	smoothened homolog (Drosophila)	0.015
KLK4	kallikrein-related peptidase 4	0.015
KLK7	kallikrein-related peptidase 7	0.014
TBX2	T-box 2	0.014
DLX5	distal-less homeobox 5	0.014
HOXC10	homeobox C10	0.014
INSM2	insulinoma-associated 2	0.014
C1QL1	complement component 1, q subcomponent-like 1	0.014
TMEM151A	transmembrane protein 151A	0.014
KCNJ4	potassium inwardly-rectifying channel, subfamily J, member 4	0.014
HOXA4	homeobox A4	0.014
KLF14	Kruppel-like factor 14	0.014
UTF1	undifferentiated embryonic cell transcription factor 1	0.014
ADAMTS17	ADAM metallopeptidase with thrombospondin type 1 motif, 17	0.014
MAST1	microtubule associated serine/threonine kinase 1	0.014
NXPH3	neurexophilin 3	0.014
HOXD3	homeobox D3	0.014
CD5	CD5 molecule	0.014
SFRP4	secreted frizzled-related protein 4	0.014
BHMT	betaine--homocysteine S-methyltransferase	0.014
TTC22	tetratricopeptide repeat domain 22	0.014
POMC	proopiomelanocortin	0.013
LRRC32	leucine rich repeat containing 32	0.013
KIAA1644	KIAA1644	0.013
AVP	arginine vasopressin	0.013
BARHL1	BarH-like homeobox 1	0.013
ADAMTS7	ADAM metallopeptidase with thrombospondin type 1 motif, 7	0.013
LFNG	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.013
HOXC13	homeobox C13	0.013
NKX2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.013
ADAMTS16	ADAM metallopeptidase with thrombospondin type 1 motif, 16	0.013
HES7	hairy and enhancer of split 7 (Drosophila)	0.013
SLC7A4	solute carrier family 7 (cationic amino acid transporter, y+ system), member 4	0.013
FAM163A	family with sequence similarity 163, member A	0.013
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.013
DLX3	distal-less homeobox 3	0.013
NTN1	netrin 1	0.013
GAS6	growth arrest-specific 6	0.013
CSDC2	cold shock domain containing C2, RNA binding	0.013
TCF21	transcription factor 21	0.013
ALX3	ALX homeobox 3	0.013
SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	0.012
SYT12	synaptotagmin XII	0.012
COL4A4	collagen, type IV, alpha 4	0.012
TRPC5	transient receptor potential cation channel, subfamily C, member 5	0.012
SCUBE1	signal peptide, CUB domain, EGF-like 1	0.012
SLMO1	slowmo homolog 1 (Drosophila)	0.012
PF4	platelet factor 4	0.012
COL9A3	collagen, type IX, alpha 3	0.012
RASL10A	RAS-like, family 10, member A	0.012
FGF10	fibroblast growth factor 10	0.012
PNOC	prepronociceptin	0.012
PLCH2	phospholipase C, eta 2	0.012
HOXC6	homeobox C6	0.012
TP73	tumor protein p73	0.012
CALCA	calcitonin-related polypeptide alpha	0.012
MSX2	msh homeobox 2	0.012
SFRP2	secreted frizzled-related protein 2	0.012
FOXD2	forkhead box D2	0.012
VEGFC	vascular endothelial growth factor C	0.012
CST1	cystatin SN	0.012
LY6D	lymphocyte antigen 6 complex, locus D	0.012
KLHL35	kelch-like 35 (Drosophila)	0.012
TACR1	tachykinin receptor 1	0.012
EPHB6	EPH receptor B6	0.012
SHOX2	short stature homeobox 2	0.012
RTN4R	reticulon 4 receptor	0.012
DENND2A	DENN/MADD domain containing 2A	0.012
LHX6	LIM homeobox 6	0.012
TCF15	transcription factor 15 (basic helix-loop-helix)	0.012
BCL2L10	BCL2-like 10 (apoptosis facilitator)	0.012
RPRML	reprimo-like	0.011
BARX2	BARX homeobox 2	0.011
HMX2	H6 family homeobox 2	0.011
INHBB	inhibin, beta B	0.011
LAMA1	laminin, alpha 1	0.011
HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.011
CARD10	caspase recruitment domain family, member 10	0.011
SP6	Sp6 transcription factor	0.011
SLITRK2	SLIT and NTRK-like family, member 2	0.011
CPNE9	copine family member IX	0.011
HOXB9	homeobox B9	0.011
KRTDAP	keratinocyte differentiation-associated protein	0.011
S100A3	S100 calcium binding protein A3	0.011
KRT14	keratin 14	0.011
MMP28	matrix metallopeptidase 28	0.011
LYPD3	LY6/PLAUR domain containing 3	0.011
GJB5	gap junction protein, beta 5, 31.1kDa	0.011
COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)	0.011
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.011
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.011
WT1	Wilms tumor 1	0.011
B4GALNT2	beta-1,4-N-acetyl-galactosaminyl transferase 2	0.011
VIPR2	vasoactive intestinal peptide receptor 2	0.011
GABRE	gamma-aminobutyric acid (GABA) A receptor, epsilon	0.011
B3GNT6	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)	0.011
SCUBE3	signal peptide, CUB domain, EGF-like 3	0.011
NKX2-2	NK2 homeobox 2	0.011
GALR2	galanin receptor 2	0.011
FMO1	flavin containing monooxygenase 1	0.011
HIST1H4E	histone cluster 1, H4e	0.011
CCBE1	collagen and calcium binding EGF domains 1	0.011
LBP	lipopolysaccharide binding protein	0.011
KRT13	keratin 13	0.011
APOA5	apolipoprotein A-V	0.011
WISP1	WNT1 inducible signaling pathway protein 1	0.011
C17orf82	chromosome 17 open reading frame 82	0.011
ONECUT2	one cut homeobox 2	0.011
GYLTL1B	glycosyltransferase-like 1B	0.011
DAPK2	death-associated protein kinase 2	0.011
KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.011
CCIN	calicin	0.011
INSM1	insulinoma-associated 1	0.010
COL4A6	collagen, type IV, alpha 6	0.010
GSTT1	glutathione S-transferase theta 1	0.010
ODF3L1	outer dense fiber of sperm tails 3-like 1	0.010
WNT16	wingless-type MMTV integration site family, member 16	0.010	Human
RSPO2	R-spondin 2 homolog (Xenopus laevis)	0.010
NKX6-2	NK6 homeobox 2	0.010
TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	0.010
ISL2	ISL LIM homeobox 2	0.010
ARSI	arylsulfatase family, member I	0.010
NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.010
HRH3	histamine receptor H3	0.010
FGF19	fibroblast growth factor 19	0.010
FAM163B	family with sequence similarity 163, member B	0.010
EYA2	eyes absent homolog 2 (Drosophila)	0.010
TWIST1	twist homolog 1 (Drosophila)	0.010
ASCL2	achaete-scute complex homolog 2 (Drosophila)	0.010
FAM101A	family with sequence similarity 101, member A	0.010
GAS1	growth arrest-specific 1	0.010
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.010