IMP

Process View

Homo sapiens

25 genes annotated in human

colon cancer

DOID:219

A colorectal cancer that is located in the colon.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "colon cancer"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "colon cancer" (in gray)

Name	Description	Probability	Func Analog Organism
CREBBP	CREB binding protein	0.295	Human
RB1	retinoblastoma 1	0.196
CDC20	cell division cycle 20 homolog (S. cerevisiae)	0.171
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.112
CTNND1	catenin (cadherin-associated protein), delta 1	0.112
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.107
CSNK1E	casein kinase 1, epsilon	0.100
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.098
MYD88	myeloid differentiation primary response gene (88)	0.084
BAK1	BCL2-antagonist/killer 1	0.069	Human
AXIN1	axin 1	0.064	Human
CDK2	cyclin-dependent kinase 2	0.052
CDK6	cyclin-dependent kinase 6	0.045
BCL2	B-cell CLL/lymphoma 2	0.043	Human
RNF144B	ring finger protein 144B	0.040
TICAM2	toll-like receptor adaptor molecule 2	0.039
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.037
PXN	paxillin	0.035
FGF1	fibroblast growth factor 1 (acidic)	0.033
TP53	tumor protein p53	0.031
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.031
LY96	lymphocyte antigen 96	0.030
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.026
CCND3	cyclin D3	0.025	Human
CCNE2	cyclin E2	0.025
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.025
KAT2B	K(lysine) acetyltransferase 2B	0.024
BUB1	budding uninhibited by benzimidazoles 1 homolog (yeast)	0.024
IRS1	insulin receptor substrate 1	0.023
MYO10	myosin X	0.021
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.020
MAD2L1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.020
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.019
GAB1	GRB2-associated binding protein 1	0.019
THAP2	THAP domain containing, apoptosis associated protein 2	0.018
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.018
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.018
APC	adenomatous polyposis coli	0.017
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.017
PSEN1	presenilin 1	0.017
GNA13	guanine nucleotide binding protein (G protein), alpha 13	0.017
NTN1	netrin 1	0.016
DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	0.016
IRAK2	interleukin-1 receptor-associated kinase 2	0.015
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.015
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.015
GSK3B	glycogen synthase kinase 3 beta	0.015
CASC5	cancer susceptibility candidate 5	0.014
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.014
UTRN	utrophin	0.014
DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1	0.014
FGFR2	fibroblast growth factor receptor 2	0.014	Human
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.013
CCNE1	cyclin E1	0.013
BTRC	beta-transducin repeat containing	0.013
MAPRE1	microtubule-associated protein, RP/EB family, member 1	0.013
CDH5	cadherin 5, type 2 (vascular endothelium)	0.013
FAM110A	family with sequence similarity 110, member A	0.013
FAM110C	family with sequence similarity 110, member C	0.013
BAD	BCL2-associated agonist of cell death	0.012
TP53BP2	tumor protein p53 binding protein, 2	0.012
HIPK2	homeodomain interacting protein kinase 2	0.012
NCOA3	nuclear receptor coactivator 3	0.012
FAM83D	family with sequence similarity 83, member D	0.012
GLIS2	GLIS family zinc finger 2	0.012
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.012
CREB1	cAMP responsive element binding protein 1	0.012
RNR2	l-rRNA	0.011
HES1	hairy and enhancer of split 1, (Drosophila)	0.011
BID	BH3 interacting domain death agonist	0.011
PTK2	PTK2 protein tyrosine kinase 2	0.011
SIRT1	sirtuin 1	0.011
C2orf44	chromosome 2 open reading frame 44	0.011
TLR1	toll-like receptor 1	0.011	Human
CADM4	cell adhesion molecule 4	0.011
CCND2	cyclin D2	0.011	Human
RUNX1	runt-related transcription factor 1	0.011
FGFR1	fibroblast growth factor receptor 1	0.011	Human
TAOK1	TAO kinase 1	0.010
AR	androgen receptor	0.010
TLR2	toll-like receptor 2	0.009
TLR4	toll-like receptor 4	0.008
MCC	mutated in colorectal cancers	0.006
PTPN12	protein tyrosine phosphatase, non-receptor type 12	0.005
EP300	E1A binding protein p300	0.005
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.004
MLH3	mutL homolog 3 (E. coli)	0.004
PDGFRL	platelet-derived growth factor receptor-like	0.004
AXIN2	axin 2	0.004
PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	0.003
FLCN	folliculin	0.003
DCC	deleted in colorectal carcinoma	0.003
BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	0.003
CCND1	cyclin D1	0.003
FGFR3	fibroblast growth factor receptor 3	0.003
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.003
NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	0.002
AURKA	aurora kinase A	0.002
BAX	BCL2-associated X protein	0.002
RAD54B	RAD54 homolog B (S. cerevisiae)	0.002
ODC1	ornithine decarboxylase 1	0.001
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.001