IMP

Process View

Homo sapiens

11 genes annotated in human

positive regulation of focal adhesion assembly

Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of focal adhesion assembly"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of focal adhesion assembly" (in gray)

Name	Description	Probability	Func Analog Organism
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	1.000	Human
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	1.000	Human
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.996
S100B	S100 calcium binding protein B	0.993	Human
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.992	Human
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.984	Human
VEGFA	vascular endothelial growth factor A	0.983
S100A8	S100 calcium binding protein A8	0.980	Human
S100A9	S100 calcium binding protein A9	0.971	Human
S100A11	S100 calcium binding protein A11	0.858	Human
PTK2	PTK2 protein tyrosine kinase 2	0.843
ANGPT2	angiopoietin 2	0.771
ANXA2	annexin A2	0.735
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.698	Human
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.669
S100A1	S100 calcium binding protein A1	0.669	Human
CDH5	cadherin 5, type 2 (vascular endothelium)	0.625
PTPRB	protein tyrosine phosphatase, receptor type, B	0.565	Human
PGF	placental growth factor	0.546	Human
S100A6	S100 calcium binding protein A6	0.521	Human
NCK2	NCK adaptor protein 2	0.483
NRP1	neuropilin 1	0.402
BCAR1	breast cancer anti-estrogen resistance 1	0.381
FHL2	four and a half LIM domains 2	0.347
GHR	growth hormone receptor	0.264
PDGFA	platelet-derived growth factor alpha polypeptide	0.255	Human
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.248
AREG	amphiregulin	0.225
TEK	TEK tyrosine kinase, endothelial	0.220
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.207
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.198
LPXN	leupaxin	0.188	Human
SMAD2	SMAD family member 2	0.181
S100A4	S100 calcium binding protein A4	0.177	Human
FXYD5	FXYD domain containing ion transport regulator 5	0.173
GAB1	GRB2-associated binding protein 1	0.163
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.157
LIMS1	LIM and senescent cell antigen-like domains 1	0.134
LAT	linker for activation of T cells	0.125
ILK	integrin-linked kinase	0.110
ANGPT1	angiopoietin 1	0.109
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.105
PLCG1	phospholipase C, gamma 1	0.104
DPYSL4	dihydropyrimidinase-like 4	0.102
PLP2	proteolipid protein 2 (colonic epithelium-enriched)	0.097
EMP3	epithelial membrane protein 3	0.096
PXN	paxillin	0.083	Human
FYN	FYN oncogene related to SRC, FGR, YES	0.080
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.076
CAPG	capping protein (actin filament), gelsolin-like	0.072
EGFR	epidermal growth factor receptor	0.069
LGALS1	lectin, galactoside-binding, soluble, 1	0.062
SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	0.061
RHOA	ras homolog gene family, member A	0.054
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.041
COL6A1	collagen, type VI, alpha 1	0.040
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.039
TSG101	tumor susceptibility gene 101	0.039
KITLG	KIT ligand	0.038
AGER	advanced glycosylation end product-specific receptor	0.036
CD34	CD34 molecule	0.035
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.035
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.035	Human
CTNND1	catenin (cadherin-associated protein), delta 1	0.034
DPPA4	developmental pluripotency associated 4	0.033
PDGFC	platelet derived growth factor C	0.031
PHC2	polyhomeotic homolog 2 (Drosophila)	0.030
TRIP6	thyroid hormone receptor interactor 6	0.030
HOXA1	homeobox A1	0.029
TMSB10	thymosin beta 10	0.028
ITGA7	integrin, alpha 7	0.027
TIMP1	TIMP metallopeptidase inhibitor 1	0.026
AXL	AXL receptor tyrosine kinase	0.026
SH3GL3	SH3-domain GRB2-like 3	0.026
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	0.025
RRAS	related RAS viral (r-ras) oncogene homolog	0.025
LGALS3	lectin, galactoside-binding, soluble, 3	0.025
CREBBP	CREB binding protein	0.023
GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	0.022
FEM1B	fem-1 homolog b (C. elegans)	0.022
PARVA	parvin, alpha	0.020
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.018
FKBP4	FK506 binding protein 4, 59kDa	0.018
STC1	stanniocalcin 1	0.018
LDLR	low density lipoprotein receptor	0.017
NCF2	neutrophil cytosolic factor 2	0.017
FLT4	fms-related tyrosine kinase 4	0.017	Human
EMCN	endomucin	0.017
RHOG	ras homolog gene family, member G (rho G)	0.017	Human
ZYX	zyxin	0.017
BGN	biglycan	0.017
S100A10	S100 calcium binding protein A10	0.017
CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	0.017
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.016
PHF21A	PHD finger protein 21A	0.016
S100A12	S100 calcium binding protein A12	0.016	Human
COL5A1	collagen, type V, alpha 1	0.016
BBS10	Bardet-Biedl syndrome 10	0.016
TSPO	translocator protein (18kDa)	0.015
COL1A1	collagen, type I, alpha 1	0.014
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.014
S100P	S100 calcium binding protein P	0.014	Human
VWF	von Willebrand factor	0.014
CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1	0.013
CSTA	cystatin A (stefin A)	0.013
GJA4	gap junction protein, alpha 4, 37kDa	0.013
ANXA5	annexin A5	0.013
PSG5	pregnancy specific beta-1-glycoprotein 5	0.012
FGFR1	fibroblast growth factor receptor 1	0.012
LMNA	lamin A/C	0.012
COTL1	coactosin-like 1 (Dictyostelium)	0.012
MMRN2	multimerin 2	0.011
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.011
ACVRL1	activin A receptor type II-like 1	0.011
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.011
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.011
AHNAK	AHNAK nucleoprotein	0.010
IGFBP5	insulin-like growth factor binding protein 5	0.010
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.010
VAT1	vesicle amine transport protein 1 homolog (T. californica)	0.010
RHOC	ras homolog gene family, member C	0.010