IMP

Process View

Homo sapiens

9 genes annotated in human

embryonic limb morphogenesis

The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "embryonic limb morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "embryonic limb morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
HDAC1	histone deacetylase 1	0.929	Mouse
HDAC2	histone deacetylase 2	0.689	Mouse
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.504
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.280
BMP2	bone morphogenetic protein 2	0.225
MEIS1	Meis homeobox 1	0.224
PSEN1	presenilin 1	0.185	Mouse
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.166
SETD8	SET domain containing (lysine methyltransferase) 8	0.135
ARRB1	arrestin, beta 1	0.098
YY1	YY1 transcription factor	0.061
TJP1	tight junction protein 1 (zona occludens 1)	0.058
RBBP4	retinoblastoma binding protein 4	0.055
BCL2L1	BCL2-like 1	0.055
HOXD13	homeobox D13	0.054	Mouse
MSX1	msh homeobox 1	0.050
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.046
AFF1	AF4/FMR2 family, member 1	0.041
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.041
BMP7	bone morphogenetic protein 7	0.040	Mouse
MSX2	msh homeobox 2	0.039	Human Mouse
MEIS2	Meis homeobox 2	0.034
TRIP6	thyroid hormone receptor interactor 6	0.033
LRP6	low density lipoprotein receptor-related protein 6	0.033	Mouse
MED13L	mediator complex subunit 13-like	0.032
CHD8	chromodomain helicase DNA binding protein 8	0.031
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.030
BAK1	BCL2-antagonist/killer 1	0.030
FGF18	fibroblast growth factor 18	0.029
HOXA11	homeobox A11	0.028	Mouse
BMPR1B	bone morphogenetic protein receptor, type IB	0.028
BAX	BCL2-associated X protein	0.028	Mouse
SATB2	SATB homeobox 2	0.026
ZFYVE9	zinc finger, FYVE domain containing 9	0.024
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.024
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.024
CREBBP	CREB binding protein	0.023
ZNF148	zinc finger protein 148	0.022
COL2A1	collagen, type II, alpha 1	0.022
BARX1	BARX homeobox 1	0.020
CCNT1	cyclin T1	0.020
FOXF2	forkhead box F2	0.020
HOXD9	homeobox D9	0.020	Mouse
JAG1	jagged 1	0.019
MLLT1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1	0.019
FOXC1	forkhead box C1	0.018
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.018	Mouse
ACAN	aggrecan	0.018
PSEN2	presenilin 2 (Alzheimer disease 4)	0.017	Mouse
HOXA10	homeobox A10	0.017
HOXC11	homeobox C11	0.016	Mouse
DLX4	distal-less homeobox 4	0.016
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	0.016
ELL2	elongation factor, RNA polymerase II, 2	0.016
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.016
SFRP1	secreted frizzled-related protein 1	0.016
PML	promyelocytic leukemia	0.016
APH1A	anterior pharynx defective 1 homolog A (C. elegans)	0.015
GATA4	GATA binding protein 4	0.015
NCOR2	nuclear receptor corepressor 2	0.015
FGF3	fibroblast growth factor 3	0.015
SMAD1	SMAD family member 1	0.015
HOXC6	homeobox C6	0.015
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.015
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.014	Mouse
NOG	noggin	0.014
PRRX2	paired related homeobox 2	0.014	Mouse
PAX3	paired box 3	0.014
BMP4	bone morphogenetic protein 4	0.014	Mouse
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.014
ATN1	atrophin 1	0.014
APC	adenomatous polyposis coli	0.013
DLX5	distal-less homeobox 5	0.013	Mouse
ERBB2IP	erbb2 interacting protein	0.013
DAXX	death-domain associated protein	0.013
HOXD11	homeobox D11	0.013	Mouse
WNT1	wingless-type MMTV integration site family, member 1	0.013	Human
NGFR	nerve growth factor receptor	0.013
CELF1	CUGBP, Elav-like family member 1	0.012
AR	androgen receptor	0.012
WISP1	WNT1 inducible signaling pathway protein 1	0.012
FLNB	filamin B, beta	0.012
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.012
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.012	Mouse
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.011
BECN1	beclin 1, autophagy related	0.011
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.011
HOXC8	homeobox C8	0.011
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.011
FZD1	frizzled homolog 1 (Drosophila)	0.011
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.011	Mouse
MAML1	mastermind-like 1 (Drosophila)	0.011
EP300	E1A binding protein p300	0.011
CABLES1	Cdk5 and Abl enzyme substrate 1	0.011
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.011
HOXC13	homeobox C13	0.011
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.011
HOXD10	homeobox D10	0.011	Mouse
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.011
HUWE1	HECT, UBA and WWE domain containing 1	0.010
GCSH	glycine cleavage system protein H (aminomethyl carrier)	0.010
SIX6	SIX homeobox 6	0.010
GATA2	GATA binding protein 2	0.010