IMP

Process View

Homo sapiens

4 genes annotated in human

nucleotide binding oligomerization domain containing signaling pathway

Any series of molecular signals generated as a consequence of binding to a nucleotide-binding oligomerization domain containing (NOD) protein.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "nucleotide binding oligomerization domain containing signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "nucleotide binding oligomerization domain containing signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	1.000	Human
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	1.000
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	1.000	Human
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.998	Human
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.989
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.985
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.970	Mouse
IRAK1	interleukin-1 receptor-associated kinase 1	0.966
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.895
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.799
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.764	Human
MYD88	myeloid differentiation primary response gene (88)	0.721
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.720
BCL3	B-cell CLL/lymphoma 3	0.689
BIRC3	baculoviral IAP repeat containing 3	0.650
RIPK2	receptor-interacting serine-threonine kinase 2	0.648
TNIP2	TNFAIP3 interacting protein 2	0.561
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.497
TRAF6	TNF receptor-associated factor 6	0.385
TICAM2	toll-like receptor adaptor molecule 2	0.273
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.190
IRAK2	interleukin-1 receptor-associated kinase 2	0.182
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.135	Human
IRAK3	interleukin-1 receptor-associated kinase 3	0.131
NOD2	nucleotide-binding oligomerization domain containing 2	0.093
LY96	lymphocyte antigen 96	0.086
TRAF1	TNF receptor-associated factor 1	0.072
BIRC2	baculoviral IAP repeat containing 2	0.069
CHUK	conserved helix-loop-helix ubiquitous kinase	0.058
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.056
HSPA1L	heat shock 70kDa protein 1-like	0.056
NLRC4	NLR family, CARD domain containing 4	0.048
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.044
PYDC2	pyrin domain containing 2	0.031
ANG	angiogenin, ribonuclease, RNase A family, 5	0.030
PYCARD	PYD and CARD domain containing	0.027
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.026
RIPK3	receptor-interacting serine-threonine kinase 3	0.022	Human
GBP5	guanylate binding protein 5	0.021
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.020
RIPK4	receptor-interacting serine-threonine kinase 4	0.020	Human
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.019	Mouse
ANKRD13A	ankyrin repeat domain 13A	0.019
SIRT6	sirtuin 6	0.019
TLR2	toll-like receptor 2	0.017
NOD1	nucleotide-binding oligomerization domain containing 1	0.017
STAP2	signal transducing adaptor family member 2	0.016
ICAM1	intercellular adhesion molecule 1	0.016
MLKL	mixed lineage kinase domain-like	0.016
NCF1	neutrophil cytosolic factor 1	0.016
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.015
IRAK4	interleukin-1 receptor-associated kinase 4	0.015
TFEC	transcription factor EC	0.015
MPRIP	myosin phosphatase Rho interacting protein	0.015
MYO1D	myosin ID	0.015
ZRANB1	zinc finger, RAN-binding domain containing 1	0.015
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.015
BTRC	beta-transducin repeat containing	0.014
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.014
ZC3H12A	zinc finger CCCH-type containing 12A	0.014
ZBP1	Z-DNA binding protein 1	0.014
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.014
COMMD1	copper metabolism (Murr1) domain containing 1	0.014
BCL2A1	BCL2-related protein A1	0.014
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.013
ACTG1	actin, gamma 1	0.013
SETD7	SET domain containing (lysine methyltransferase) 7	0.013
TPM3	tropomyosin 3	0.013
TICAM1	toll-like receptor adaptor molecule 1	0.013
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.013
SQSTM1	sequestosome 1	0.012
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.012
TRAF3IP2	TRAF3 interacting protein 2	0.012
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.012
MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric	0.012
TRAF2	TNF receptor-associated factor 2	0.012
TLR1	toll-like receptor 1	0.011
ZAN	zonadhesin	0.011
SERTAD1	SERTA domain containing 1	0.011
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.011
KLF5	Kruppel-like factor 5 (intestinal)	0.011
KIF2B	kinesin family member 2B	0.011
TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.011
MEFV	Mediterranean fever	0.010
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.010