IMP

Process View

Homo sapiens

4 genes annotated in human

positive regulation of transcription initiation from rna polymerase ii promoter

Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of transcription initiation from rna polymerase ii promoter"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of transcription initiation from rna polymerase ii promoter" (in gray)

Name	Description	Probability	Func Analog Organism
PSMD10	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	0.999
PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	0.980
PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.965
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.835
PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	0.827
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	0.826
PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	0.778	Yeast
DCP1A	DCP1 decapping enzyme homolog A (S. cerevisiae)	0.722
PSMC5	proteasome (prosome, macropain) 26S subunit, ATPase, 5	0.663	Yeast
PSMD13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	0.623
PSMD6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.504
PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	0.439
PSMC4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	0.436	Yeast
TBP	TATA box binding protein	0.412	Fly
PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2	0.407	Yeast
NCOA6	nuclear receptor coactivator 6	0.395
LEO1	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.322
RB1	retinoblastoma 1	0.309
TBX5	T-box 5	0.243
TAF1	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	0.239	Fly
NBN	nibrin	0.235
UCHL5	ubiquitin carboxyl-terminal hydrolase L5	0.216
KAT2B	K(lysine) acetyltransferase 2B	0.201
EP300	E1A binding protein p300	0.197
CREBBP	CREB binding protein	0.176
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.154
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.141
PAF1	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	0.134
RTF1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.119
TP53BP1	tumor protein p53 binding protein 1	0.108
PSMB7	proteasome (prosome, macropain) subunit, beta type, 7	0.098
TAF5	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa	0.094
XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	0.093
STAG1	stromal antigen 1	0.091
PSMD9	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9	0.085
POLR2A	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	0.082
USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	0.078
HDAC1	histone deacetylase 1	0.078
MKL1	megakaryoblastic leukemia (translocation) 1	0.077
H2AFX	H2A histone family, member X	0.071
NCOA3	nuclear receptor coactivator 3	0.061
ARNT	aryl hydrocarbon receptor nuclear translocator	0.058
TAF1C	TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa	0.057
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.048
NCOA1	nuclear receptor coactivator 1	0.047
SUPT16H	suppressor of Ty 16 homolog (S. cerevisiae)	0.047	Yeast
NCOA2	nuclear receptor coactivator 2	0.047
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.045
PRKDC	protein kinase, DNA-activated, catalytic polypeptide	0.044
CUX1	cut-like homeobox 1	0.042
TP53	tumor protein p53	0.038
ATM	ataxia telangiectasia mutated	0.036
PSMB5	proteasome (prosome, macropain) subunit, beta type, 5	0.035
TAF1B	TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa	0.034
MYOCD	myocardin	0.033
HNF4A	hepatocyte nuclear factor 4, alpha	0.033
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.033
CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.032
E2F3	E2F transcription factor 3	0.032
PSMB6	proteasome (prosome, macropain) subunit, beta type, 6	0.030
GATA4	GATA binding protein 4	0.029
RAD50	RAD50 homolog (S. cerevisiae)	0.029
AR	androgen receptor	0.027
CTR9	Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.027
MYOG	myogenin (myogenic factor 4)	0.027
FAM190B	family with sequence similarity 190, member B	0.026
TRRAP	transformation/transcription domain-associated protein	0.026
MYOD1	myogenic differentiation 1	0.025
UPF2	UPF2 regulator of nonsense transcripts homolog (yeast)	0.025
NCOA7	nuclear receptor coactivator 7	0.024
RNF8	ring finger protein 8	0.023
GTF2A1	general transcription factor IIA, 1, 19/37kDa	0.022
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.022
POLR1A	polymerase (RNA) I polypeptide A, 194kDa	0.022
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.021
NCOR2	nuclear receptor corepressor 2	0.021
HDGF	hepatoma-derived growth factor	0.021
NONO	non-POU domain containing, octamer-binding	0.021
RUNX1	runt-related transcription factor 1	0.021
ERCC3	excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)	0.020
MAPK14	mitogen-activated protein kinase 14	0.020
SIRT1	sirtuin 1	0.020
MRE11A	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	0.019
PSMD8	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	0.018
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.017
MED26	mediator complex subunit 26	0.017
RBBP5	retinoblastoma binding protein 5	0.016
PAAF1	proteasomal ATPase-associated factor 1	0.016
CD3EAP	CD3e molecule, epsilon associated protein	0.016
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.016
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.016
TAF12	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa	0.016
TAF1A	TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa	0.016
MKL2	MKL/myocardin-like 2	0.016
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.015
PSMD5	proteasome (prosome, macropain) 26S subunit, non-ATPase, 5	0.015
PURA	purine-rich element binding protein A	0.015
POLR1E	polymerase (RNA) I polypeptide E, 53kDa	0.015
MCMBP	minichromosome maintenance complex binding protein	0.015
BRF1	BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae)	0.014
MYST3	MYST histone acetyltransferase (monocytic leukemia) 3	0.014
MCM7	minichromosome maintenance complex component 7	0.014
TAF11	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa	0.014
PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.014
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	0.014
CENPT	centromere protein T	0.014
HNF1A	HNF1 homeobox A	0.013
WRN	Werner syndrome, RecQ helicase-like	0.013
MAGED2	melanoma antigen family D, 2	0.012
MSH6	mutS homolog 6 (E. coli)	0.012
DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.012
SSRP1	structure specific recognition protein 1	0.012	Yeast
FTSJ3	FtsJ homolog 3 (E. coli)	0.012
PCBD2	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2	0.012
PROX1	prospero homeobox 1	0.012
HIPK2	homeodomain interacting protein kinase 2	0.011
MAGEA11	melanoma antigen family A, 11	0.011
MDC1	mediator of DNA-damage checkpoint 1	0.011	Human
E2F2	E2F transcription factor 2	0.011
FANCD2	Fanconi anemia, complementation group D2	0.011
RAD23B	RAD23 homolog B (S. cerevisiae)	0.011
CHD4	chromodomain helicase DNA binding protein 4	0.011
GFI1B	growth factor independent 1B transcription repressor	0.011
APC	adenomatous polyposis coli	0.011
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.011
ESR1	estrogen receptor 1	0.011
CDX2	caudal type homeobox 2	0.011
BAZ1B	bromodomain adjacent to zinc finger domain, 1B	0.011
EXOSC10	exosome component 10	0.011
TAF3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa	0.010
FOXO1	forkhead box O1	0.010
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.010