IMP

Process View

Homo sapiens

13 genes annotated in human

negative regulation of production of molecular mediator of immune response

Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of production of molecular mediator of immune response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of production of molecular mediator of immune response" (in gray)

Name	Description	Probability	Func Analog Organism
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.855
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.789
CXCL2	chemokine (C-X-C motif) ligand 2	0.691
ALB	albumin	0.641
PILRA	paired immunoglobin-like type 2 receptor alpha	0.577
HP	haptoglobin	0.540
CCL4	chemokine (C-C motif) ligand 4	0.435	Human
CD14	CD14 molecule	0.339
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.324	Human
APOC1	apolipoprotein C-I	0.286
MYD88	myeloid differentiation primary response gene (88)	0.262
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.240
CXCL9	chemokine (C-X-C motif) ligand 9	0.211
CCR1	chemokine (C-C motif) receptor 1	0.209
IL22RA2	interleukin 22 receptor, alpha 2	0.196
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.192
CCL8	chemokine (C-C motif) ligand 8	0.180	Human
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.119	Human
CCR4	chemokine (C-C motif) receptor 4	0.098
IRAK2	interleukin-1 receptor-associated kinase 2	0.080
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.079	Human
CCL7	chemokine (C-C motif) ligand 7	0.076	Human
IL8	interleukin 8	0.074
EPOR	erythropoietin receptor	0.072
IL22RA1	interleukin 22 receptor, alpha 1	0.069
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.067	Human
TEK	TEK tyrosine kinase, endothelial	0.067
CCR5	chemokine (C-C motif) receptor 5	0.067
IL10	interleukin 10	0.064
SOCS3	suppressor of cytokine signaling 3	0.064
IL10RA	interleukin 10 receptor, alpha	0.059
IDE	insulin-degrading enzyme	0.057
CCL2	chemokine (C-C motif) ligand 2	0.056	Human
IL1B	interleukin 1, beta	0.056
NCOR2	nuclear receptor corepressor 2	0.054
THOC5	THO complex 5	0.052
APOC3	apolipoprotein C-III	0.049
HDAC9	histone deacetylase 9	0.047
SIGLEC7	sialic acid binding Ig-like lectin 7	0.047
TGFB1	transforming growth factor, beta 1	0.046
THOC4	THO complex 4	0.045
LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	0.044	Human
CCL22	chemokine (C-C motif) ligand 22	0.043	Human
APOC2	apolipoprotein C-II	0.041
CCL5	chemokine (C-C motif) ligand 5	0.041	Human
APOA2	apolipoprotein A-II	0.039
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.039
NLRP3	NLR family, pyrin domain containing 3	0.038
HK3	hexokinase 3 (white cell)	0.035
IFNG	interferon, gamma	0.035
CCL13	chemokine (C-C motif) ligand 13	0.034	Human
DDX39B	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	0.032
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.032
CCR7	chemokine (C-C motif) receptor 7	0.031
APOA1	apolipoprotein A-I	0.030
THOC2	THO complex 2	0.030
CXCL10	chemokine (C-X-C motif) ligand 10	0.030
NKG7	natural killer cell group 7 sequence	0.029
FGA	fibrinogen alpha chain	0.029
IL6	interleukin 6 (interferon, beta 2)	0.028
TNF	tumor necrosis factor	0.026
ZNF830	zinc finger protein 830	0.025
DPP4	dipeptidyl-peptidase 4	0.024
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.023
IL1RN	interleukin 1 receptor antagonist	0.023
ENG	endoglin	0.023
KRT15	keratin 15	0.022
FSTL1	follistatin-like 1	0.022
PCDH9	protocadherin 9	0.022
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.022
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.022
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.021
FRA10AC1	fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1	0.021
CXCL11	chemokine (C-X-C motif) ligand 11	0.021
TRAF1	TNF receptor-associated factor 1	0.020
TREM1	triggering receptor expressed on myeloid cells 1	0.019
ZC3H12A	zinc finger CCCH-type containing 12A	0.019
CCL19	chemokine (C-C motif) ligand 19	0.019	Human
PTAFR	platelet-activating factor receptor	0.019
EBI3	Epstein-Barr virus induced 3	0.018
CXCL5	chemokine (C-X-C motif) ligand 5	0.018
CXCL13	chemokine (C-X-C motif) ligand 13	0.018
ITGB1BP1	integrin beta 1 binding protein 1	0.018
CXCL3	chemokine (C-X-C motif) ligand 3	0.018
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.018	Human
AOAH	acyloxyacyl hydrolase (neutrophil)	0.017
FPR3	formyl peptide receptor 3	0.017
CSF1	colony stimulating factor 1 (macrophage)	0.017
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.016
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.015
IGF2	insulin-like growth factor 2 (somatomedin A)	0.015
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.015
CH25H	cholesterol 25-hydroxylase	0.015
MARCO	macrophage receptor with collagenous structure	0.014
BCL2A1	BCL2-related protein A1	0.014
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.014
LCAT	lecithin-cholesterol acyltransferase	0.014
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.014
CCL3	chemokine (C-C motif) ligand 3	0.014	Human
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.014
SIRPB1	signal-regulatory protein beta 1	0.013
IL2RA	interleukin 2 receptor, alpha	0.013
FCGR2C	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	0.013
ANGPT2	angiopoietin 2	0.013
CCL23	chemokine (C-C motif) ligand 23	0.012	Human
LILRB4	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	0.011	Human
IRF4	interferon regulatory factor 4	0.011
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.011
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.011
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.011
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.011
CD83	CD83 molecule	0.011
FPR2	formyl peptide receptor 2	0.010