IMP

Process View

Homo sapiens

4 genes annotated in human

renal system process involved in regulation of blood volume

GO:0001977

A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "renal system process involved in regulation of blood volume"

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Name	Description	Probability	Func Analog Organism
CAV1	caveolin 1, caveolae protein, 22kDa	0.995
AXL	AXL receptor tyrosine kinase	0.964
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.912
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.549
COL6A1	collagen, type VI, alpha 1	0.425
SH3GL3	SH3-domain GRB2-like 3	0.389
LGALS1	lectin, galactoside-binding, soluble, 1	0.357
DPYSL4	dihydropyrimidinase-like 4	0.260
PDGFA	platelet-derived growth factor alpha polypeptide	0.257
ADORA2A	adenosine A2a receptor	0.169
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.124
TIMP1	TIMP metallopeptidase inhibitor 1	0.097
PTRF	polymerase I and transcript release factor	0.093
COL5A1	collagen, type V, alpha 1	0.092
FXYD5	FXYD domain containing ion transport regulator 5	0.092
COL4A1	collagen, type IV, alpha 1	0.085
CAV2	caveolin 2	0.073
CD99	CD99 molecule	0.070
PDGFC	platelet derived growth factor C	0.063
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.058
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.057	Human
SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	0.056
PRKCDBP	protein kinase C, delta binding protein	0.056
S100A4	S100 calcium binding protein A4	0.054
VEGFA	vascular endothelial growth factor A	0.054
S100A6	S100 calcium binding protein A6	0.051
CYP4F11	cytochrome P450, family 4, subfamily F, polypeptide 11	0.047	Human
CAPG	capping protein (actin filament), gelsolin-like	0.044
PROCR	protein C receptor, endothelial	0.038
ANXA5	annexin A5	0.037
SRPX	sushi-repeat containing protein, X-linked	0.036
TSPAN4	tetraspanin 4	0.036
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.036
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.036
SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	0.034
TMSB10	thymosin beta 10	0.033
COL6A2	collagen, type VI, alpha 2	0.032
S100A11	S100 calcium binding protein A11	0.032
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.032
MDFI	MyoD family inhibitor	0.032
COL2A1	collagen, type II, alpha 1	0.031
SH3GL1	SH3-domain GRB2-like 1	0.030
PLCG1	phospholipase C, gamma 1	0.029
COL1A1	collagen, type I, alpha 1	0.029
CD97	CD97 molecule	0.028
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.028	Human
DAO	D-amino-acid oxidase	0.028
TAGLN2	transgelin 2	0.027
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5	0.027
PLP2	proteolipid protein 2 (colonic epithelium-enriched)	0.026
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.026
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.025
S100A10	S100 calcium binding protein A10	0.024
NBL1	neuroblastoma, suppression of tumorigenicity 1	0.024
THBS1	thrombospondin 1	0.024
HTRA1	HtrA serine peptidase 1	0.023
COL1A2	collagen, type I, alpha 2	0.022
MAT1A	methionine adenosyltransferase I, alpha	0.022
PRLR	prolactin receptor	0.021
COL4A2	collagen, type IV, alpha 2	0.021
IGFBP6	insulin-like growth factor binding protein 6	0.021
ANXA6	annexin A6	0.019
CSRP1	cysteine and glycine-rich protein 1	0.019
KNG1	kininogen 1	0.019
GJA1	gap junction protein, alpha 1, 43kDa	0.019
ROM1	retinal outer segment membrane protein 1	0.019
LMNA	lamin A/C	0.019
IFITM2	interferon induced transmembrane protein 2 (1-8D)	0.018
TGFBI	transforming growth factor, beta-induced, 68kDa	0.018
CYP4B1	cytochrome P450, family 4, subfamily B, polypeptide 1	0.018	Human
AZGP1	alpha-2-glycoprotein 1, zinc-binding	0.018
DIO1	deiodinase, iodothyronine, type I	0.017
RIMS3	regulating synaptic membrane exocytosis 3	0.016
PAH	phenylalanine hydroxylase	0.016
LAMB2	laminin, beta 2 (laminin S)	0.016
SLC22A1	solute carrier family 22 (organic cation transporter), member 1	0.016
HAL	histidine ammonia-lyase	0.016
VIM	vimentin	0.016
EPHX2	epoxide hydrolase 2, cytoplasmic	0.016
ENG	endoglin	0.016
SULT1E1	sulfotransferase family 1E, estrogen-preferring, member 1	0.016
OSGIN1	oxidative stress induced growth inhibitor 1	0.016
MGP	matrix Gla protein	0.016
GFER	growth factor, augmenter of liver regeneration	0.016
CD63	CD63 molecule	0.016
C20orf4	chromosome 20 open reading frame 4	0.015
PTPRF	protein tyrosine phosphatase, receptor type, F	0.015
EDNRB	endothelin receptor type B	0.015
LRP1	low density lipoprotein receptor-related protein 1	0.015
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	0.015
UNC5B	unc-5 homolog B (C. elegans)	0.015
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.015
EHD2	EH-domain containing 2	0.015
CFD	complement factor D (adipsin)	0.015
PTEN	phosphatase and tensin homolog	0.015
PLAT	plasminogen activator, tissue	0.015
ADH6	alcohol dehydrogenase 6 (class V)	0.015
S100A13	S100 calcium binding protein A13	0.015
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.015
AADAC	arylacetamide deacetylase (esterase)	0.015
EMP1	epithelial membrane protein 1	0.014
DRD1	dopamine receptor D1	0.014
ZCCHC24	zinc finger, CCHC domain containing 24	0.014
PLG	plasminogen	0.014
DPYS	dihydropyrimidinase	0.014
NRP1	neuropilin 1	0.014
CLDN8	claudin 8	0.014
ANXA2	annexin A2	0.014
DBH	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	0.014
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.014
SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1	0.014
MCAM	melanoma cell adhesion molecule	0.014
TXNRD1	thioredoxin reductase 1	0.014
CYP2C18	cytochrome P450, family 2, subfamily C, polypeptide 18	0.014
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.014
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.014
UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3	0.014
FABP2	fatty acid binding protein 2, intestinal	0.014
SULT2B1	sulfotransferase family, cytosolic, 2B, member 1	0.014
PLEKHG6	pleckstrin homology domain containing, family G (with RhoGef domain) member 6	0.014
RDH16	retinol dehydrogenase 16 (all-trans)	0.014
COL6A3	collagen, type VI, alpha 3	0.013
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.013
TRPV2	transient receptor potential cation channel, subfamily V, member 2	0.013
MYLK	myosin light chain kinase	0.013
FABP1	fatty acid binding protein 1, liver	0.013
RAB34	RAB34, member RAS oncogene family	0.013
IFITM3	interferon induced transmembrane protein 3 (1-8U)	0.013
CYP4F8	cytochrome P450, family 4, subfamily F, polypeptide 8	0.013	Human
C8B	complement component 8, beta polypeptide	0.013
SDPR	serum deprivation response	0.013
DEFB1	defensin, beta 1	0.013
SERPING1	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1	0.013
CLIC1	chloride intracellular channel 1	0.013
PIPOX	pipecolic acid oxidase	0.013
BHMT	betaine--homocysteine S-methyltransferase	0.013
PPFIA4	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4	0.013
TINAGL1	tubulointerstitial nephritis antigen-like 1	0.013
SLC38A3	solute carrier family 38, member 3	0.013
GPT	glutamic-pyruvate transaminase (alanine aminotransferase)	0.013
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.013
FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)	0.013
SYT12	synaptotagmin XII	0.013
SCNN1A	sodium channel, nonvoltage-gated 1 alpha	0.013
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.013
ABCC3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	0.013
GLYAT	glycine-N-acyltransferase	0.013
HPN	hepsin	0.013
SEC14L2	SEC14-like 2 (S. cerevisiae)	0.012
TMEM40	transmembrane protein 40	0.012
COL16A1	collagen, type XVI, alpha 1	0.012
MPZL2	myelin protein zero-like 2	0.012
G6PC	glucose-6-phosphatase, catalytic subunit	0.012
FETUB	fetuin B	0.012
MASP2	mannan-binding lectin serine peptidase 2	0.012
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.012
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.012
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.012
ADH1C	alcohol dehydrogenase 1C (class I), gamma polypeptide	0.012
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.012
CRYL1	crystallin, lambda 1	0.012
VTCN1	V-set domain containing T cell activation inhibitor 1	0.012
MT1H	metallothionein 1H	0.012
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.012
IL22RA1	interleukin 22 receptor, alpha 1	0.012
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	0.012
SLC17A1	solute carrier family 17 (sodium phosphate), member 1	0.012
CRX	cone-rod homeobox	0.012
AGXT	alanine-glyoxylate aminotransferase	0.012
PKDREJ	polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin)	0.012
FILIP1L	filamin A interacting protein 1-like	0.012
CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2	0.012
PPAP2B	phosphatidic acid phosphatase type 2B	0.012
TM4SF5	transmembrane 4 L six family member 5	0.012
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.012
AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	0.012
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7	0.012
HAO1	hydroxyacid oxidase (glycolate oxidase) 1	0.012
ARG1	arginase, liver	0.012
GBA3	glucosidase, beta, acid 3 (cytosolic)	0.012
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.011
LYPD3	LY6/PLAUR domain containing 3	0.011
PTPRN	protein tyrosine phosphatase, receptor type, N	0.011
VEGFC	vascular endothelial growth factor C	0.011
GSTA3	glutathione S-transferase alpha 3	0.011
YBX2	Y box binding protein 2	0.011
TRAM2	translocation associated membrane protein 2	0.011
EVC2	Ellis van Creveld syndrome 2	0.011
C4BPA	complement component 4 binding protein, alpha	0.011
SLC13A2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	0.011
C9	complement component 9	0.011
PIP	prolactin-induced protein	0.011
CES1	carboxylesterase 1	0.011
SLC12A3	solute carrier family 12 (sodium/chloride transporters), member 3	0.011
HAO2	hydroxyacid oxidase 2 (long chain)	0.011
ECM1	extracellular matrix protein 1	0.011
GSTT1	glutathione S-transferase theta 1	0.011
TRPV4	transient receptor potential cation channel, subfamily V, member 4	0.011
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.011
CPB2	carboxypeptidase B2 (plasma)	0.011
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.011
COL3A1	collagen, type III, alpha 1	0.011
PROC	protein C (inactivator of coagulation factors Va and VIIIa)	0.011
MT1F	metallothionein 1F	0.011
CA9	carbonic anhydrase IX	0.011
LGALS3	lectin, galactoside-binding, soluble, 3	0.011
IL1RL2	interleukin 1 receptor-like 2	0.011
CYP17A1	cytochrome P450, family 17, subfamily A, polypeptide 1	0.011
HSD3B2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.011
ALDH1L1	aldehyde dehydrogenase 1 family, member L1	0.011
CA5A	carbonic anhydrase VA, mitochondrial	0.011
FCGRT	Fc fragment of IgG, receptor, transporter, alpha	0.011
ETNK2	ethanolamine kinase 2	0.011
ADRA1A	adrenergic, alpha-1A-, receptor	0.011
BST1	bone marrow stromal cell antigen 1	0.011
S100A14	S100 calcium binding protein A14	0.011
DRD2	dopamine receptor D2	0.011
GNG11	guanine nucleotide binding protein (G protein), gamma 11	0.011
PTPRB	protein tyrosine phosphatase, receptor type, B	0.011
CLCN2	chloride channel 2	0.011
PARVA	parvin, alpha	0.011
CD44	CD44 molecule (Indian blood group)	0.011
SLC13A3	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3	0.011
N4BP3	NEDD4 binding protein 3	0.011
ZNF707	zinc finger protein 707	0.011
NID1	nidogen 1	0.011
KLKB1	kallikrein B, plasma (Fletcher factor) 1	0.011
HR	hairless homolog (mouse)	0.011
CPS1	carbamoyl-phosphate synthase 1, mitochondrial	0.011
LTBP2	latent transforming growth factor beta binding protein 2	0.011
C3	complement component 3	0.011
CRHBP	corticotropin releasing hormone binding protein	0.011
CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1	0.011
LTBP4	latent transforming growth factor beta binding protein 4	0.011
PLA2G4F	phospholipase A2, group IVF	0.011
PNLIPRP1	pancreatic lipase-related protein 1	0.010
TTPA	tocopherol (alpha) transfer protein	0.010
ACSM5	acyl-CoA synthetase medium-chain family member 5	0.010
SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	0.010
VTN	vitronectin	0.010
MARK1	MAP/microtubule affinity-regulating kinase 1	0.010
DLC1	deleted in liver cancer 1	0.010
EVX1	even-skipped homeobox 1	0.010
APOH	apolipoprotein H (beta-2-glycoprotein I)	0.010
SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.010
FSTL3	follistatin-like 3 (secreted glycoprotein)	0.010
SPHK1	sphingosine kinase 1	0.010
GPR12	G protein-coupled receptor 12	0.010
SLC34A1	solute carrier family 34 (sodium phosphate), member 1	0.010
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8	0.010
PODXL	podocalyxin-like	0.010
INHBB	inhibin, beta B	0.010
PTPRH	protein tyrosine phosphatase, receptor type, H	0.010
TMPRSS2	transmembrane protease, serine 2	0.010
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.010
SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.010
IGFBP5	insulin-like growth factor binding protein 5	0.010
RDH5	retinol dehydrogenase 5 (11-cis/9-cis)	0.010
TEK	TEK tyrosine kinase, endothelial	0.010
SLC6A12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.010
PRODH2	proline dehydrogenase (oxidase) 2	0.010
CYP8B1	cytochrome P450, family 8, subfamily B, polypeptide 1	0.010
CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6	0.010
GPRC5A	G protein-coupled receptor, family C, group 5, member A	0.010
WISP2	WNT1 inducible signaling pathway protein 2	0.010
HPD	4-hydroxyphenylpyruvate dioxygenase	0.010