IMP

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Homo sapiens

26 genes annotated in human

Multi-species View

regulation of phospholipase activity

GO:0010517

Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of phospholipase activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of phospholipase activity" (in gray)

Name	Description	Probability	Func Analog Organism
FGF1	fibroblast growth factor 1 (acidic)	0.998	Human
FGFR1	fibroblast growth factor receptor 1	0.983
PLCG1	phospholipase C, gamma 1	0.877
ARRB1	arrestin, beta 1	0.810
CCR5	chemokine (C-C motif) receptor 5	0.698
MAPT	microtubule-associated protein tau	0.653
CTGF	connective tissue growth factor	0.531
FGFR2	fibroblast growth factor receptor 2	0.517
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.502
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.412
MPDZ	multiple PDZ domain protein	0.379
CXCL9	chemokine (C-X-C motif) ligand 9	0.324
CCL2	chemokine (C-C motif) ligand 2	0.250	Human
CCL4	chemokine (C-C motif) ligand 4	0.234	Human
S100A10	S100 calcium binding protein A10	0.216
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.215
ARFIP2	ADP-ribosylation factor interacting protein 2	0.209
RNASE4	ribonuclease, RNase A family, 4	0.206	Human
SPRR2A	small proline-rich protein 2A	0.176
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.162
VCAM1	vascular cell adhesion molecule 1	0.151
ANG	angiogenin, ribonuclease, RNase A family, 5	0.137
GAB1	GRB2-associated binding protein 1	0.135
ANXA5	annexin A5	0.134	Human
CDH5	cadherin 5, type 2 (vascular endothelium)	0.103
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.091	Human
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.089
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.085
CRP	C-reactive protein, pentraxin-related	0.081
RAB1A	RAB1A, member RAS oncogene family	0.077
ANXA1	annexin A1	0.072	Human
KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	0.061
BCAR1	breast cancer anti-estrogen resistance 1	0.058
DARC	Duffy blood group, chemokine receptor	0.057
CCL8	chemokine (C-C motif) ligand 8	0.054	Human
ANXA2	annexin A2	0.054	Human
VPS29	vacuolar protein sorting 29 homolog (S. cerevisiae)	0.053
RLN3	relaxin 3	0.050
IL6	interleukin 6 (interferon, beta 2)	0.049
SLA	Src-like-adaptor	0.046
CCL5	chemokine (C-C motif) ligand 5	0.046
CCL7	chemokine (C-C motif) ligand 7	0.044	Human
FGA	fibrinogen alpha chain	0.042
GSK3B	glycogen synthase kinase 3 beta	0.041
SOS1	son of sevenless homolog 1 (Drosophila)	0.041
SELE	selectin E	0.039
PDGFC	platelet derived growth factor C	0.038
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.038
HTT	huntingtin	0.037
ARF4	ADP-ribosylation factor 4	0.037
LRP1	low density lipoprotein receptor-related protein 1	0.037	Mouse
ITGB5	integrin, beta 5	0.036
ARRDC3	arrestin domain containing 3	0.036
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.036
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.035
CCR1	chemokine (C-C motif) receptor 1	0.035
CCR7	chemokine (C-C motif) receptor 7	0.035
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.034
IL10	interleukin 10	0.034
VEGFA	vascular endothelial growth factor A	0.034
CCL13	chemokine (C-C motif) ligand 13	0.033	Human
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.033
IL1B	interleukin 1, beta	0.031
FYB	FYN binding protein	0.031
CCL3	chemokine (C-C motif) ligand 3	0.030	Human
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.029	Human
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.029
CTSB	cathepsin B	0.028
TMED2	transmembrane emp24 domain trafficking protein 2	0.028
TIMP3	TIMP metallopeptidase inhibitor 3	0.027
ARCN1	archain 1	0.027
CCR3	chemokine (C-C motif) receptor 3	0.027
KITLG	KIT ligand	0.026
CCL22	chemokine (C-C motif) ligand 22	0.026
TRAM1	translocation associated membrane protein 1	0.025
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.025
FGFR3	fibroblast growth factor receptor 3	0.025
EEF2	eukaryotic translation elongation factor 2	0.024
IL7R	interleukin 7 receptor	0.023
C4orf14	chromosome 4 open reading frame 14	0.022
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.022
REEP5	receptor accessory protein 5	0.021
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.021
APP	amyloid beta (A4) precursor protein	0.021
EMP1	epithelial membrane protein 1	0.021
CXCL13	chemokine (C-X-C motif) ligand 13	0.021
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.021
PGF	placental growth factor	0.020
FGB	fibrinogen beta chain	0.020
IFNG	interferon, gamma	0.019
RIN1	Ras and Rab interactor 1	0.019
SHB	Src homology 2 domain containing adaptor protein B	0.019
EGFR	epidermal growth factor receptor	0.019
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.019
AGTR1	angiotensin II receptor, type 1	0.019
CARD11	caspase recruitment domain family, member 11	0.018
HPGDS	hematopoietic prostaglandin D synthase	0.018
OR2AG1	olfactory receptor, family 2, subfamily AG, member 1	0.018
ADORA3	adenosine A3 receptor	0.018
CPA3	carboxypeptidase A3 (mast cell)	0.018
STAT4	signal transducer and activator of transcription 4	0.018
NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.017
FGF7	fibroblast growth factor 7	0.017	Human
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.017
CYTH2	cytohesin 2	0.017
FGF2	fibroblast growth factor 2 (basic)	0.017
CCR2	chemokine (C-C motif) receptor 2	0.017
CTSG	cathepsin G	0.016
APOE	apolipoprotein E	0.016
CALU	calumenin	0.016
CXCL5	chemokine (C-X-C motif) ligand 5	0.016
SELP	selectin P (granule membrane protein 140kDa, antigen CD62)	0.016	Human
APOC1	apolipoprotein C-I	0.016
CD83	CD83 molecule	0.016
PDGFA	platelet-derived growth factor alpha polypeptide	0.016
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.016
CCL23	chemokine (C-C motif) ligand 23	0.016	Human
GPR171	G protein-coupled receptor 171	0.015
S100A11	S100 calcium binding protein A11	0.015
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.015
PTPRB	protein tyrosine phosphatase, receptor type, B	0.015
CMIP	c-Maf-inducing protein	0.015
FLT4	fms-related tyrosine kinase 4	0.015	Human
LAT	linker for activation of T cells	0.015
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.015
CCL11	chemokine (C-C motif) ligand 11	0.015	Human
KRT8	keratin 8	0.014
RNH1	ribonuclease/angiogenin inhibitor 1	0.014
F13A1	coagulation factor XIII, A1 polypeptide	0.014
CCR4	chemokine (C-C motif) receptor 4	0.014
RIN3	Ras and Rab interactor 3	0.014
MBL2	mannose-binding lectin (protein C) 2, soluble	0.014
CH25H	cholesterol 25-hydroxylase	0.014
FPR3	formyl peptide receptor 3	0.014
SOCS3	suppressor of cytokine signaling 3	0.014
HNF4A	hepatocyte nuclear factor 4, alpha	0.014
CXCL10	chemokine (C-X-C motif) ligand 10	0.013
GLTSCR2	glioma tumor suppressor candidate region gene 2	0.013
IL8	interleukin 8	0.013
WDR13	WD repeat domain 13	0.013
YIPF5	Yip1 domain family, member 5	0.013
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.013
IL18RAP	interleukin 18 receptor accessory protein	0.012
HSPG2	heparan sulfate proteoglycan 2	0.012
HP	haptoglobin	0.012
RABAC1	Rab acceptor 1 (prenylated)	0.012
LDLR	low density lipoprotein receptor	0.012
IL2RB	interleukin 2 receptor, beta	0.012
ZNF71	zinc finger protein 71	0.012
LGALS3	lectin, galactoside-binding, soluble, 3	0.012
DPP4	dipeptidyl-peptidase 4	0.012
FASLG	Fas ligand (TNF superfamily, member 6)	0.012
C2	complement component 2	0.012
SEC22B	SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)	0.012
NMT2	N-myristoyltransferase 2	0.012
CXCL11	chemokine (C-X-C motif) ligand 11	0.011
IL2RG	interleukin 2 receptor, gamma	0.011
PTEN	phosphatase and tensin homolog	0.011
IL10RA	interleukin 10 receptor, alpha	0.011
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.011
TMEM106A	transmembrane protein 106A	0.011
BDKRB1	bradykinin receptor B1	0.011	Human
TMED10	transmembrane emp24-like trafficking protein 10 (yeast)	0.011
SELPLG	selectin P ligand	0.011
AQP9	aquaporin 9	0.011
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.011
GFPT1	glutamine--fructose-6-phosphate transaminase 1	0.011
TFEC	transcription factor EC	0.011
GHR	growth hormone receptor	0.011
SPAG9	sperm associated antigen 9	0.011
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.011	Human
FRS2	fibroblast growth factor receptor substrate 2	0.011
HDC	histidine decarboxylase	0.011
CAV2	caveolin 2	0.011
C9orf16	chromosome 9 open reading frame 16	0.011
CD28	CD28 molecule	0.011
CD163	CD163 molecule	0.011
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.010
EZR	ezrin	0.010
C12orf23	chromosome 12 open reading frame 23	0.010
AXL	AXL receptor tyrosine kinase	0.010
ICOS	inducible T-cell co-stimulator	0.010
VPS28	vacuolar protein sorting 28 homolog (S. cerevisiae)	0.010
RGS16	regulator of G-protein signaling 16	0.010
RGS1	regulator of G-protein signaling 1	0.010
C1orf93	chromosome 1 open reading frame 93	0.010