IMP

Process View

Mus musculus

3 genes annotated in mouse

response to host

Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to host"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to host" (in gray)

Name	Description	Probability	Func Analog Organism
Tlr4	toll-like receptor 4	0.996	Mouse
Tgfb1	transforming growth factor, beta 1	0.988	Human
Ccr2	chemokine (C-C motif) receptor 2	0.912
Vdr	vitamin D receptor	0.683
Tlr2	toll-like receptor 2	0.588
Kit	kit oncogene	0.478
Il10	interleukin 10	0.459
Lepr	leptin receptor	0.431
Gucy1a3	guanylate cyclase 1, soluble, alpha 3	0.412
Ticam1	toll-like receptor adaptor molecule 1	0.310
Stat3	signal transducer and activator of transcription 3	0.264
Spp1	secreted phosphoprotein 1	0.240
Smad4	MAD homolog 4 (Drosophila)	0.215
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.178	Mouse
Pparg	peroxisome proliferator activated receptor gamma	0.147
Sparcl1	SPARC-like 1	0.144
Kitl	kit ligand	0.142
Myd88	myeloid differentiation primary response gene 88	0.139
Il6st	interleukin 6 signal transducer	0.130
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.118
Cd33	CD33 antigen	0.106
Cd44	CD44 antigen	0.098
Cd300ld	CD300 molecule-like family member d	0.089
Irak4	interleukin-1 receptor-associated kinase 4	0.083
Mef2c	myocyte enhancer factor 2C	0.078
Lair1	leukocyte-associated Ig-like receptor 1	0.065
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.057
Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.056
Fcgr1	Fc receptor, IgG, high affinity I	0.054
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.047
Bcl2	B-cell leukemia/lymphoma 2	0.042
Cd14	CD14 antigen	0.040
Slamf8	SLAM family member 8	0.038
Unc93b1	unc-93 homolog B1 (C. elegans)	0.036
Apc	adenomatosis polyposis coli	0.035
Lcp1	lymphocyte cytosolic protein 1	0.034
Mmp9	matrix metallopeptidase 9	0.033
Cysltr1	cysteinyl leukotriene receptor 1	0.027
Ly96	lymphocyte antigen 96	0.027
Naip6	NLR family, apoptosis inhibitory protein 6	0.027
Pkia	protein kinase inhibitor, alpha	0.026
Gnb4	guanine nucleotide binding protein (G protein), beta 4	0.025
Hpgds	hematopoietic prostaglandin D synthase	0.024
Emr4	EGF-like module containing, mucin-like, hormone receptor-like sequence 4	0.024
Abcg3	ATP-binding cassette, sub-family G (WHITE), member 3	0.024
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.022
Hhex	hematopoietically expressed homeobox	0.021
Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.021
Hdac7	histone deacetylase 7	0.020
Ptgs2	prostaglandin-endoperoxide synthase 2	0.020
Lat2	linker for activation of T cells family, member 2	0.020
Clec5a	C-type lectin domain family 5, member a	0.020
Tmem173	transmembrane protein 173	0.019
Ncoa3	nuclear receptor coactivator 3	0.019
Agtr1a	angiotensin II receptor, type 1a	0.019
Slamf6	SLAM family member 6	0.019
Sirpa	signal-regulatory protein alpha	0.019
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.019
Csf1	colony stimulating factor 1 (macrophage)	0.018
Tlr9	toll-like receptor 9	0.018
Aim2	absent in melanoma 2	0.018
B9d2	B9 protein domain 2	0.018
4933421A08Rik	RIKEN cDNA 4933421A08 gene	0.017
Ank	progressive ankylosis	0.017
Apobr	apolipoprotein B receptor	0.017
Stk11	serine/threonine kinase 11	0.017
Stap1	signal transducing adaptor family member 1	0.016
Vav3	vav 3 oncogene	0.016
Nhej1	nonhomologous end-joining factor 1	0.016
Ticam2	toll-like receptor adaptor molecule 2	0.016
Vhl	von Hippel-Lindau tumor suppressor	0.015
Csprs	component of Sp100-rs	0.015
Axin1	axin 1	0.015
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.015
Havcr2	hepatitis A virus cellular receptor 2	0.015
Naip2	NLR family, apoptosis inhibitory protein 2	0.015
Casp1	caspase 1	0.015
Plekho2	pleckstrin homology domain containing, family O member 2	0.015
Lyz2	lysozyme 2	0.015
Kynu	kynureninase (L-kynurenine hydrolase)	0.015
Trem1	triggering receptor expressed on myeloid cells 1	0.014
4931429L15Rik	RIKEN cDNA 4931429L15 gene	0.014
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.014
Cd84	CD84 antigen	0.014
Xpnpep2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	0.014
Tspan7	tetraspanin 7	0.014
Olfr558	olfactory receptor 558	0.014
Cysltr2	cysteinyl leukotriene receptor 2	0.014
Zfp54	zinc finger protein 54	0.013
Itga9	integrin alpha 9	0.013
Cblc	Casitas B-lineage lymphoma c	0.013
Tspan2	tetraspanin 2	0.013
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.013
Vav2	vav 2 oncogene	0.013
Tlr6	toll-like receptor 6	0.012	Mouse
Clec7a	C-type lectin domain family 7, member a	0.012
Spats2l	spermatogenesis associated, serine-rich 2-like	0.012
Dmrtc1c2	DMRT-like family C1c2	0.012
Mcoln3	mucolipin 3	0.012
Nr3c2	nuclear receptor subfamily 3, group C, member 2	0.012
Ly9	lymphocyte antigen 9	0.012
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.012
Igsf6	immunoglobulin superfamily, member 6	0.012
Rad51l3	RAD51-like 3 (S. cerevisiae)	0.012
Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.012
Slamf7	SLAM family member 7	0.012
Fcgr4	Fc receptor, IgG, low affinity IV	0.012
Lyst	lysosomal trafficking regulator	0.012
Btbd3	BTB (POZ) domain containing 3	0.012
P2ry12	purinergic receptor P2Y, G-protein coupled 12	0.012
Ramp1	receptor (calcitonin) activity modifying protein 1	0.012
Tceal1	transcription elongation factor A (SII)-like 1	0.012
Esr1	estrogen receptor 1 (alpha)	0.012
Plekhn1	pleckstrin homology domain containing, family N member 1	0.012
Nlrp3	NLR family, pyrin domain containing 3	0.011
4933423P22Rik	RIKEN cDNA 4933423P22 gene	0.011
Col1a1	collagen, type I, alpha 1	0.011
Nos2	nitric oxide synthase 2, inducible	0.011
Cd69	CD69 antigen	0.011
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.011
Tlcd2	TLC domain containing 2	0.011
Bcl9l	B-cell CLL/lymphoma 9-like	0.011
Fam81b	family with sequence similarity 81, member B	0.011
Gabre	gamma-aminobutyric acid (GABA) A receptor, subunit epsilon	0.011
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.011
Tlr5	toll-like receptor 5	0.011	Mouse
Dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.011
4930545L23Rik	RIKEN cDNA 4930545L23 gene	0.010
4930565D16Rik	RIKEN cDNA 4930565D16 gene	0.010
Rgs5	regulator of G-protein signaling 5	0.010
Asah2	N-acylsphingosine amidohydrolase 2	0.010
5430427O19Rik	RIKEN cDNA 5430427O19 gene	0.010
Oaz2-ps	ornithine decarboxylase antizyme 2, pseudogene	0.010
Epsti1	epithelial stromal interaction 1 (breast)	0.010
Prr15l	proline rich 15-like	0.010
Nos1	nitric oxide synthase 1, neuronal	0.010
Fam115a	family with sequence similarity 115, member A	0.010
Nrg2	neuregulin 2	0.010