IMP

Process View

Mus musculus

3 genes annotated in mouse

intermediate filament bundle assembly

The formation of the bundles of intermediate filaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "intermediate filament bundle assembly"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "intermediate filament bundle assembly" (in gray)

Name	Description	Probability	Func Analog Organism
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.985
Nefl	neurofilament, light polypeptide	0.947
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.888
Nefm	neurofilament, medium polypeptide	0.873
Des	desmin	0.764	Mouse
Ina	internexin neuronal intermediate filament protein, alpha	0.591	Mouse
Krt15	keratin 15	0.497
Prph	peripherin	0.407	Mouse
Ppt1	palmitoyl-protein thioesterase 1	0.354
Scg3	secretogranin III	0.336
Napb	N-ethylmaleimide sensitive fusion protein attachment protein beta	0.326
Tubb2c	tubulin, beta 2C	0.293
Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.289
Nefh	neurofilament, heavy polypeptide	0.284
Dab1	disabled homolog 1 (Drosophila)	0.282
Celf4	CUGBP, Elav-like family member 4	0.271
Cryab	crystallin, alpha B	0.255
Sync	syncoilin	0.249	Mouse
Pkp1	plakophilin 1	0.202	Human
Actc1	actin, alpha, cardiac muscle 1	0.192
Jph3	junctophilin 3	0.190
Flnc	filamin C, gamma	0.188
Krt14	keratin 14	0.184	Human
Snap25	synaptosomal-associated protein 25	0.158
Krt17	keratin 17	0.157
Epha2	Eph receptor A2	0.149
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.108
Krtdap	keratinocyte differentiation associated protein	0.106
Gng3	guanine nucleotide binding protein (G protein), gamma 3	0.104
Sult4a1	sulfotransferase family 4A, member 1	0.101
Serpinb5	serine (or cysteine) peptidase inhibitor, clade B, member 5	0.092
Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)	0.078
Ank1	ankyrin 1, erythroid	0.074
Tcfap2c	transcription factor AP-2, gamma	0.071
Tubb3	tubulin, beta 3	0.064
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.063
Cadps	Ca2+-dependent secretion activator	0.062
Hpca	hippocalcin	0.059
Tnnt3	troponin T3, skeletal, fast	0.059
Krt13	keratin 13	0.055
Tpm2	tropomyosin 2, beta	0.055
Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	0.054
Cntn2	contactin 2	0.051
Nrsn1	neurensin 1	0.051
Crmp1	collapsin response mediator protein 1	0.050
Gdnf	glial cell line derived neurotrophic factor	0.050
Cacna2d3	calcium channel, voltage-dependent, alpha2/delta subunit 3	0.050
Fbxo32	F-box protein 32	0.049
Nphp1	nephronophthisis 1 (juvenile) homolog (human)	0.048
Stmn4	stathmin-like 4	0.044
Resp18	regulated endocrine-specific protein 18	0.041
Vsx2	visual system homeobox 2	0.040
Stmn3	stathmin-like 3	0.039
Neurod1	neurogenic differentiation 1	0.037
Nppc	natriuretic peptide type C	0.037
Pcsk2	proprotein convertase subtilisin/kexin type 2	0.035
Calb2	calbindin 2	0.035
Lgr5	leucine rich repeat containing G protein coupled receptor 5	0.034
Ldb3	LIM domain binding 3	0.034
Cplx1	complexin 1	0.032
Kcnmb1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.032
Cit	citron	0.031
Insm1	insulinoma-associated 1	0.031
Fxyd7	FXYD domain-containing ion transport regulator 7	0.030
Nap1l2	nucleosome assembly protein 1-like 2	0.030
Duoxa1	dual oxidase maturation factor 1	0.030
Irx4	Iroquois related homeobox 4 (Drosophila)	0.030
Snap91	synaptosomal-associated protein 91	0.030
Slc6a1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	0.028
Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.028
Mapk8ip2	mitogen-activated protein kinase 8 interacting protein 2	0.027
Krt1	keratin 1	0.027
Rab33a	RAB33A, member of RAS oncogene family	0.027
Mtap2	microtubule-associated protein 2	0.026
Mab21l2	mab-21-like 2 (C. elegans)	0.026
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.026
Syt9	synaptotagmin IX	0.024
Ache	acetylcholinesterase	0.024
Syt2	synaptotagmin II	0.024
Casq1	calsequestrin 1	0.024
Cwh43	cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)	0.024
Tubb6	tubulin, beta 6	0.024
Tuba1b	tubulin, alpha 1B	0.024
Actn2	actinin alpha 2	0.023
Cartpt	CART prepropeptide	0.023
Try10	trypsin 10	0.023
Actn3	actinin alpha 3	0.023
Ebf3	early B-cell factor 3	0.022
Sox10	SRY-box containing gene 10	0.022
Atp1a3	ATPase, Na+/K+ transporting, alpha 3 polypeptide	0.022
Zic1	zinc finger protein of the cerebellum 1	0.022
Tuba1a	tubulin, alpha 1A	0.022
Spock1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1	0.022
Anxa8	annexin A8	0.022
Sprr1b	small proline-rich protein 1B	0.022
Cbln1	cerebellin 1 precursor protein	0.021
Kcnd2	potassium voltage-gated channel, Shal-related family, member 2	0.021
Gal	galanin	0.021
Krt6a	keratin 6A	0.021
Hoxd1	homeobox D1	0.021
Prkce	protein kinase C, epsilon	0.020
Nrip3	nuclear receptor interacting protein 3	0.020
Pcsk1n	proprotein convertase subtilisin/kexin type 1 inhibitor	0.020
Syn1	synapsin I	0.019
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.019
Orc1	origin recognition complex, subunit 1	0.019
Mall	mal, T-cell differentiation protein-like	0.019
Scg2	secretogranin II	0.019
Uchl1	ubiquitin carboxy-terminal hydrolase L1	0.019
Bves	blood vessel epicardial substance	0.019
Sez6l	seizure related 6 homolog like	0.018
Chga	chromogranin A	0.018
S100a14	S100 calcium binding protein A14	0.018
Elavl3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.018
Nhlh1	nescient helix loop helix 1	0.017
Klk11	kallikrein related-peptidase 11	0.017
Hcn1	hyperpolarization-activated, cyclic nucleotide-gated K+ 1	0.017
Isl1	ISL1 transcription factor, LIM/homeodomain	0.017
Cbln3	cerebellin 3 precursor protein	0.017
Hspb2	heat shock protein 2	0.017
Tuba4a	tubulin, alpha 4A	0.016
Tnni1	troponin I, skeletal, slow 1	0.016
2310002J15Rik	RIKEN cDNA 2310002J15 gene	0.016
Tagln3	transgelin 3	0.016
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.015
Trim29	tripartite motif-containing 29	0.015
Gsdma	gasdermin A	0.015
Adcyap1	adenylate cyclase activating polypeptide 1	0.015
St8sia3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	0.015
Calcb	calcitonin-related polypeptide, beta	0.015
Ugt8a	UDP galactosyltransferase 8A	0.014
Ctnna2	catenin (cadherin associated protein), alpha 2	0.014
Acta1	actin, alpha 1, skeletal muscle	0.014
Cntn1	contactin 1	0.014
Fgf18	fibroblast growth factor 18	0.014
Klk10	kallikrein related-peptidase 10	0.014
Mapk10	mitogen-activated protein kinase 10	0.014
Mmp17	matrix metallopeptidase 17	0.014
Dpp6	dipeptidylpeptidase 6	0.014
Hspa8	heat shock protein 8	0.013
Fgfbp1	fibroblast growth factor binding protein 1	0.013
Id3	inhibitor of DNA binding 3	0.013
Mybph	myosin binding protein H	0.013
Tnni2	troponin I, skeletal, fast 2	0.013
Gata3	GATA binding protein 3	0.013
Ppl	periplakin	0.013
Wnk2	WNK lysine deficient protein kinase 2	0.013
Mnx1	motor neuron and pancreas homeobox 1	0.013
Wnt3	wingless-related MMTV integration site 3	0.013
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.013
Basp1	brain abundant, membrane attached signal protein 1	0.013
Rpgrip1l	Rpgrip1-like	0.013
Sv2a	synaptic vesicle glycoprotein 2 a	0.012
Tram1l1	translocation associated membrane protein 1-like 1	0.012
Kcnj12	potassium inwardly-rectifying channel, subfamily J, member 12	0.012
Tmem54	transmembrane protein 54	0.012
Grik3	glutamate receptor, ionotropic, kainate 3	0.012
Slc46a2	solute carrier family 46, member 2	0.012
Hpcal1	hippocalcin-like 1	0.011
Phox2a	paired-like homeobox 2a	0.011
Gpr87	G protein-coupled receptor 87	0.011
Hspb1	heat shock protein 1	0.011
Amph	amphiphysin	0.011
Sh3gl2	SH3-domain GRB2-like 2	0.011
Sprr1a	small proline-rich protein 1A	0.011
Sez6l2	seizure related 6 homolog like 2	0.011
Tmem40	transmembrane protein 40	0.011
Ndrg4	N-myc downstream regulated gene 4	0.011
Tubb2a	tubulin, beta 2A	0.010
Pou4f3	POU domain, class 4, transcription factor 3	0.010
Ckm	creatine kinase, muscle	0.010
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.010
Gap43	growth associated protein 43	0.010
Hoxb9	homeobox B9	0.010
Cnn1	calponin 1	0.010
Fmn2	formin 2	0.010
Fez1	fasciculation and elongation protein zeta 1 (zygin I)	0.010