IMP

Process View

Mus musculus

8 genes annotated in mouse

Multi-species View

retinal cone cell differentiation

GO:0042670

The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "retinal cone cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "retinal cone cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Pax2	paired box gene 2	0.962	Fly
Otx2	orthodenticle homolog 2 (Drosophila)	0.903
Thra	thyroid hormone receptor alpha	0.861
Crb2	crumbs homolog 2 (Drosophila)	0.855
Rho	rhodopsin	0.773
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.759
Sox2	SRY-box containing gene 2	0.747
Duox2	dual oxidase 2	0.593
Pax6	paired box gene 6	0.585	Zebrafish
Atxn1	ataxin 1	0.489
Tbx5	T-box 5	0.479
Gucy2d	guanylate cyclase 2d	0.455
Thrb	thyroid hormone receptor beta	0.438	Zebrafish
Reln	reelin	0.436
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.419
Scn5a	sodium channel, voltage-gated, type V, alpha	0.339
Neurod1	neurogenic differentiation 1	0.288
Trpm1	transient receptor potential cation channel, subfamily M, member 1	0.269
Pou4f2	POU domain, class 4, transcription factor 2	0.231
Lhx3	LIM homeobox protein 3	0.226
Pcp2	Purkinje cell protein 2 (L7)	0.215
Myo6	myosin VI	0.214
Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.201
ND6	NADH dehydrogenase subunit 6	0.182
Crx	cone-rod homeobox containing gene	0.182
Eya1	eyes absent 1 homolog (Drosophila)	0.175
Tyr	tyrosinase	0.173
Gja5	gap junction protein, alpha 5	0.150
Tbx3	T-box 3	0.147
Pitx2	paired-like homeodomain transcription factor 2	0.143
Pex5l	peroxisomal biogenesis factor 5-like	0.143
Emx2	empty spiracles homolog 2 (Drosophila)	0.136
Dlx5	distal-less homeobox 5	0.125
Rbp3	retinol binding protein 3, interstitial	0.120
Gucy2e	guanylate cyclase 2e	0.112
Igl	immunoglobulin lambda chain complex	0.106
Emx1	empty spiracles homolog 1 (Drosophila)	0.100
Pten	phosphatase and tensin homolog	0.092
Ghr	growth hormone receptor	0.092
Tshz1	teashirt zinc finger family member 1	0.091
Insm1	insulinoma-associated 1	0.087
Cbl	Casitas B-lineage lymphoma	0.083
Otx1	orthodenticle homolog 1 (Drosophila)	0.081
Kcnc1	potassium voltage gated channel, Shaw-related subfamily, member 1	0.080
Aipl1	aryl hydrocarbon receptor-interacting protein-like 1	0.074
Drd2	dopamine receptor D2	0.071
Rax	retina and anterior neural fold homeobox	0.068
Lhx1	LIM homeobox protein 1	0.067
Zeb1	zinc finger E-box binding homeobox 1	0.066
Isl1	ISL1 transcription factor, LIM/homeodomain	0.066
Prph2	peripherin 2	0.064
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.064
Opn1mw	opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)	0.062
Rorb	RAR-related orphan receptor beta	0.062
Cplx4	complexin 4	0.061
Tshr	thyroid stimulating hormone receptor	0.059
Hcn1	hyperpolarization-activated, cyclic nucleotide-gated K+ 1	0.055
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.051
AI118078	expressed sequence AI118078	0.050
Cacna2d4	calcium channel, voltage-dependent, alpha 2/delta subunit 4	0.048
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.047
Lepr	leptin receptor	0.047
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.046
Gnb3	guanine nucleotide binding protein (G protein), beta 3	0.046
Opn1sw	opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)	0.045
BC027072	cDNA sequence BC027072	0.044
Rap2c	RAP2C, member of RAS oncogene family	0.044
Cacna1f	calcium channel, voltage-dependent, alpha 1F subunit	0.043
Vsx2	visual system homeobox 2	0.041
Tbx10	T-box 10	0.041
Gata3	GATA binding protein 3	0.041
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.041
Pdc	phosducin	0.040
Gdf5	growth differentiation factor 5	0.040
Atp2b1	ATPase, Ca++ transporting, plasma membrane 1	0.038
Mab21l2	mab-21-like 2 (C. elegans)	0.038
Neurod4	neurogenic differentiation 4	0.037
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.037	Mouse
Abca4	ATP-binding cassette, sub-family A (ABC1), member 4	0.037
Ptf1a	pancreas specific transcription factor, 1a	0.036
Rac1	RAS-related C3 botulinum substrate 1	0.036
Pax8	paired box gene 8	0.036	Fly
Ppard	peroxisome proliferator activator receptor delta	0.035
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.034
Atoh7	atonal homolog 7 (Drosophila)	0.034
Pde6h	phosphodiesterase 6H, cGMP-specific, cone, gamma	0.032
Cbln1	cerebellin 1 precursor protein	0.031
Rgs7	regulator of G protein signaling 7	0.030
Chd7	chromodomain helicase DNA binding protein 7	0.030
Tulp1	tubby like protein 1	0.030
Cav1	caveolin 1, caveolae protein	0.029
Tgfb1	transforming growth factor, beta 1	0.029
Guca1b	guanylate cyclase activator 1B	0.029
Rarb	retinoic acid receptor, beta	0.029
Shh	sonic hedgehog	0.029
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.028
Guca1a	guanylate cyclase activator 1a (retina)	0.028
Gpd2	glycerol phosphate dehydrogenase 2, mitochondrial	0.028
Arr3	arrestin 3, retinal	0.028
Fto	fat mass and obesity associated	0.027
Jag1	jagged 1	0.027
Chrna6	cholinergic receptor, nicotinic, alpha polypeptide 6	0.026
Rara	retinoic acid receptor, alpha	0.025
Gabra2	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2	0.025
Gbx2	gastrulation brain homeobox 2	0.025
Fgf3	fibroblast growth factor 3	0.024
Mitf	microphthalmia-associated transcription factor	0.024
Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	0.024
Tpo	thyroid peroxidase	0.023
Wnt9b	wingless-type MMTV integration site 9B	0.023
Mc1r	melanocortin 1 receptor	0.023
Tyrp1	tyrosinase-related protein 1	0.022
Dct	dopachrome tautomerase	0.022
Ugdh	UDP-glucose dehydrogenase	0.022
Vdr	vitamin D receptor	0.022
Cabp4	calcium binding protein 4	0.021
Grb10	growth factor receptor bound protein 10	0.021
Adrb1	adrenergic receptor, beta 1	0.021
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.021
Celf4	CUGBP, Elav-like family member 4	0.021
Efnb2	ephrin B2	0.020
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.020
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.020
Rxra	retinoid X receptor alpha	0.020
Aip	aryl-hydrocarbon receptor-interacting protein	0.020
Grk1	G protein-coupled receptor kinase 1	0.020
Fgfr2	fibroblast growth factor receptor 2	0.019
BC024139	cDNA sequence BC024139	0.019
Purb	purine rich element binding protein B	0.019
Foxg1	forkhead box G1	0.019
Igf1r	insulin-like growth factor I receptor	0.019
Rtbdn	retbindin	0.019
Tll2	tolloid-like 2	0.019
Slc24a1	solute carrier family 24 (sodium/potassium/calcium exchanger), member 1	0.018
Gli3	GLI-Kruppel family member GLI3	0.018
Crxos1	Crx opposite strand transcript 1	0.018
Crybb2	crystallin, beta B2	0.018
Impg1	interphotoreceptor matrix proteoglycan 1	0.018
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.018
Lef1	lymphoid enhancer binding factor 1	0.018
Slc12a5	solute carrier family 12, member 5	0.018
Sobp	sine oculis-binding protein homolog (Drosophila)	0.017
Slc17a8	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8	0.017
Ccdc85c	coiled-coil domain containing 85C	0.017
Foxe1	forkhead box E1	0.017
Ppef2	protein phosphatase, EF hand calcium-binding domain 2	0.017
Pde6g	phosphodiesterase 6G, cGMP-specific, rod, gamma	0.017
Lmx1a	LIM homeobox transcription factor 1 alpha	0.017
Rod1	ROD1 regulator of differentiation 1 (S. pombe)	0.016
Tmod3	tropomodulin 3	0.016
Cabp5	calcium binding protein 5	0.016	Mouse
Syt9	synaptotagmin IX	0.015
Ankrd33	ankyrin repeat domain 33	0.015
Pacsin1	protein kinase C and casein kinase substrate in neurons 1	0.015
Rit2	Ras-like without CAAX 2	0.015
Plxna2	plexin A2	0.015
Ctnnb1	catenin (cadherin associated protein), beta 1	0.015
Abca17	ATP-binding cassette, sub-family A (ABC1), member 17	0.014
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.014
Rp1l1	retinitis pigmentosa 1 homolog (human)-like 1	0.014	Mouse
Dlg4	discs, large homolog 4 (Drosophila)	0.014
Tcfap2a	transcription factor AP-2, alpha	0.014
Slc26a4	solute carrier family 26, member 4	0.014
Prkce	protein kinase C, epsilon	0.014
Cngb3	cyclic nucleotide gated channel beta 3	0.014	Mouse
Atg5	autophagy-related 5 (yeast)	0.014
Ebf3	early B-cell factor 3	0.014
Ssr3	signal sequence receptor, gamma	0.014
Pde1c	phosphodiesterase 1C	0.014
Syt1	synaptotagmin I	0.013
4933407C03Rik	RIKEN cDNA 4933407C03 gene	0.013
Akt1	thymoma viral proto-oncogene 1	0.013
Ncoa1	nuclear receptor coactivator 1	0.013
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.013
Cyld	cylindromatosis (turban tumor syndrome)	0.013
Crybb3	crystallin, beta B3	0.013
Mlf2	myeloid leukemia factor 2	0.013
Gngt1	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	0.013
Gck	glucokinase	0.013
Gabrr1	gamma-aminobutyric acid (GABA) C receptor, subunit rho 1	0.013
Fgfr1	fibroblast growth factor receptor 1	0.013
Foxc1	forkhead box C1	0.013
Kalrn	kalirin, RhoGEF kinase	0.013
Rps6ka4	ribosomal protein S6 kinase, polypeptide 4	0.013
Drd4	dopamine receptor D4	0.013
Dscam	Down syndrome cell adhesion molecule	0.013
Syp	synaptophysin	0.013
Msx2	homeobox, msh-like 2	0.013
Hlf	hepatic leukemia factor	0.013
Glg1	golgi apparatus protein 1	0.012
Gabrr2	gamma-aminobutyric acid (GABA) C receptor, subunit rho 2	0.012
Kl	klotho	0.012
Pde6b	phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide	0.012	Mouse
Mapk14	mitogen-activated protein kinase 14	0.012
Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	0.012
Zfpm2	zinc finger protein, multitype 2	0.012
Agtr1a	angiotensin II receptor, type 1a	0.012
Igf2	insulin-like growth factor 2	0.012
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.012
Ankrd2	ankyrin repeat domain 2 (stretch responsive muscle)	0.012
Bdnf	brain derived neurotrophic factor	0.012
Mtap1b	microtubule-associated protein 1B	0.012
Dio3	deiodinase, iodothyronine type III	0.012
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.012
Papln	papilin, proteoglycan-like sulfated glycoprotein	0.012
Trp53	transformation related protein 53	0.012
Epha8	Eph receptor A8	0.012
Rap1b	RAS related protein 1b	0.012
Mab21l1	mab-21-like 1 (C. elegans)	0.012
Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	0.012
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.012
Nxnl2	nucleoredoxin-like 2	0.012
Grm8	glutamate receptor, metabotropic 8	0.012
Lhx4	LIM homeobox protein 4	0.012
Rd3	retinal degeneration 3	0.011
Adcy9	adenylate cyclase 9	0.011
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.011
Ucn	urocortin	0.011
Insr	insulin receptor	0.011
Mapk8ip2	mitogen-activated protein kinase 8 interacting protein 2	0.011
Sag	retinal S-antigen	0.011
Gng2	guanine nucleotide binding protein (G protein), gamma 2	0.011
Slc6a5	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	0.011
Kcnd2	potassium voltage-gated channel, Shal-related family, member 2	0.011
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.011
Rgs9bp	regulator of G-protein signalling 9 binding protein	0.011
Fscn2	fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)	0.011
Prox1	prospero-related homeobox 1	0.011	Fly
Cfl1	cofilin 1, non-muscle	0.011
Mafa	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)	0.011
Lhx2	LIM homeobox protein 2	0.011
Zic2	zinc finger protein of the cerebellum 2	0.011
Neurog2	neurogenin 2	0.011
Rlbp1	retinaldehyde binding protein 1	0.011
Nrl	neural retina leucine zipper gene	0.011
Vax1	ventral anterior homeobox containing gene 1	0.011
Bhlhe41	basic helix-loop-helix family, member e41	0.011
Gsbs	G substrate	0.011
Akt1s1	AKT1 substrate 1 (proline-rich)	0.011
Lrit1	leucine-rich repeat, immunoglobulin-like and transmembrane domains 1	0.011
Aes	amino-terminal enhancer of split	0.010
Nxnl1	nucleoredoxin-like 1	0.010
Rgr	retinal G protein coupled receptor	0.010
Dsg4	desmoglein 4	0.010
Ncoa3	nuclear receptor coactivator 3	0.010
Gpr152	G protein-coupled receptor 152	0.010
Cbfb	core binding factor beta	0.010