IMP

Process View

Mus musculus

2 genes annotated in mouse

floor plate formation

The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage.

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In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "floor plate formation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "floor plate formation" (in gray)

Name	Description	Probability	Func Analog Organism
Gli3	GLI-Kruppel family member GLI3	1.000	Mouse
Shh	sonic hedgehog	1.000	Zebrafish
Fgfr2	fibroblast growth factor receptor 2	0.971
Gli2	GLI-Kruppel family member GLI2	0.970
Sox9	SRY-box containing gene 9	0.886
Foxc1	forkhead box C1	0.860
Nodal	nodal	0.843
Pitx2	paired-like homeodomain transcription factor 2	0.824
Bmp4	bone morphogenetic protein 4	0.813
Fgfr1	fibroblast growth factor receptor 1	0.601
Bmp7	bone morphogenetic protein 7	0.569
Msx1	homeobox, msh-like 1	0.481
Otx2	orthodenticle homolog 2 (Drosophila)	0.478
Mks1	Meckel syndrome, type 1	0.471
Chrd	chordin	0.464
Vangl2	vang-like 2 (van gogh, Drosophila)	0.424
Smo	smoothened homolog (Drosophila)	0.357	Zebrafish
Fgf10	fibroblast growth factor 10	0.347
Prrx1	paired related homeobox 1	0.335
Zic3	zinc finger protein of the cerebellum 3	0.332
Foxc2	forkhead box C2	0.307
Pax3	paired box gene 3	0.305
Tgfb2	transforming growth factor, beta 2	0.304
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.293
Disp1	dispatched homolog 1 (Drosophila)	0.229
Meox2	mesenchyme homeobox 2	0.192
Dnahc11	dynein, axonemal, heavy chain 11	0.189
Msx2	homeobox, msh-like 2	0.189
Fgf8	fibroblast growth factor 8	0.171
Ctnnb1	catenin (cadherin associated protein), beta 1	0.114
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.112
Nog	noggin	0.112
Fgfr3	fibroblast growth factor receptor 3	0.111
Tbx1	T-box 1	0.096
Zeb1	zinc finger E-box binding homeobox 1	0.092
Ptch1	patched homolog 1	0.091
Tcfap2a	transcription factor AP-2, alpha	0.085
Hand1	heart and neural crest derivatives expressed transcript 1	0.082
Foxh1	forkhead box H1	0.080	Zebrafish
Rarb	retinoic acid receptor, beta	0.076
Rarg	retinoic acid receptor, gamma	0.067
Twist2	twist homolog 2 (Drosophila)	0.067
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.066
Col2a1	collagen, type II, alpha 1	0.066
Lefty1	left right determination factor 1	0.057
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.056
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.053
Prrx2	paired related homeobox 2	0.051
Gdf1	growth differentiation factor 1	0.051
Dlx5	distal-less homeobox 5	0.049
En1	engrailed 1	0.049
Eya1	eyes absent 1 homolog (Drosophila)	0.046
Dnahc5	dynein, axonemal, heavy chain 5	0.044
Kif3a	kinesin family member 3A	0.040
Foxj1	forkhead box J1	0.037
Cfc1	cripto, FRL-1, cryptic family 1	0.035	Zebrafish
Pax6	paired box gene 6	0.034
Hand2	heart and neural crest derivatives expressed transcript 2	0.033
Sox11	SRY-box containing gene 11	0.031
Gsc	goosecoid homeobox	0.030
Invs	inversin	0.029
Lrp6	low density lipoprotein receptor-related protein 6	0.027
Lmx1b	LIM homeobox transcription factor 1 beta	0.027
Pbx1	pre B-cell leukemia transcription factor 1	0.025
Ptk7	PTK7 protein tyrosine kinase 7	0.022
Pthlh	parathyroid hormone-like peptide	0.022
Megf8	multiple EGF-like-domains 8	0.021
Npr2	natriuretic peptide receptor 2	0.020
Tbx6	T-box 6	0.020
Insm1	insulinoma-associated 1	0.020
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.020
Lhx1	LIM homeobox protein 1	0.020
Ihh	Indian hedgehog	0.020
Isl1	ISL1 transcription factor, LIM/homeodomain	0.019
Emid2	EMI domain containing 2	0.018
Fgf9	fibroblast growth factor 9	0.018
En2	engrailed 2	0.017
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.017
Runx2	runt related transcription factor 2	0.017
Zic2	zinc finger protein of the cerebellum 2	0.017
Emx2	empty spiracles homolog 2 (Drosophila)	0.016
Smad3	MAD homolog 3 (Drosophila)	0.016
Sox2	SRY-box containing gene 2	0.016
Wnt5a	wingless-related MMTV integration site 5A	0.015
Alx1	ALX homeobox 1	0.015
Ptch2	patched homolog 2	0.015
Foxg1	forkhead box G1	0.015
Pitx1	paired-like homeodomain transcription factor 1	0.015
Hoxa5	homeobox A5	0.014
Gbx2	gastrulation brain homeobox 2	0.014
Crlf1	cytokine receptor-like factor 1	0.014
Hoxa2	homeobox A2	0.013
Nkx3-2	NK3 homeobox 2	0.013
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.013
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.013
Pax9	paired box gene 9	0.012
Hesx1	homeobox gene expressed in ES cells	0.012
Rara	retinoic acid receptor, alpha	0.012
Efna4	ephrin A4	0.012
Acvr2b	activin receptor IIB	0.012
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.012
Foxa2	forkhead box A2	0.011
Bmper	BMP-binding endothelial regulator	0.011
Pax2	paired box gene 2	0.011
Vmn2r1	vomeronasal 2, receptor 1	0.011
Efnb2	ephrin B2	0.011
Mn1	meningioma 1	0.011
Cldn6	claudin 6	0.011
Trp63	transformation related protein 63	0.011
Gata4	GATA binding protein 4	0.010
Hoxb3	homeobox B3	0.010
Fzd2	frizzled homolog 2 (Drosophila)	0.010
Hoxd3	homeobox D3	0.010