IMP

Process View

Mus musculus

2 genes annotated in mouse

Multi-species View

nadph regeneration

GO:0006740

A metabolic process that generates a pool of NADPH by the reduction of NADP+.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "nadph regeneration"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "nadph regeneration" (in gray)

Name	Description	Probability	Func Analog Organism
Pgk1	phosphoglycerate kinase 1	0.995
Pgd	phosphogluconate dehydrogenase	0.945
Pkm2	pyruvate kinase, muscle	0.889
Aldoa	aldolase A, fructose-bisphosphate	0.856
Taldo1	transaldolase 1	0.748
Ldha	lactate dehydrogenase A	0.745
Gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.732
Hsd11b1	hydroxysteroid 11-beta dehydrogenase 1	0.724	Rat
Aldh1a1	aldehyde dehydrogenase family 1, subfamily A1	0.437	Yeast
Fasn	fatty acid synthase	0.405
Gsta3	glutathione S-transferase, alpha 3	0.363
Tpi1	triosephosphate isomerase 1	0.353
Fmo5	flavin containing monooxygenase 5	0.350
Gpi1	glucose phosphate isomerase 1	0.334
Aldh1a7	aldehyde dehydrogenase family 1, subfamily A7	0.254	Yeast
H6pd	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	0.213
Gm5506	predicted gene 5506	0.180
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.143
Gstm1	glutathione S-transferase, mu 1	0.127
Pfkl	phosphofructokinase, liver, B-type	0.122
Sult1a1	sulfotransferase family 1A, phenol-preferring, member 1	0.104
Ak2	adenylate kinase 2	0.103
Adh1	alcohol dehydrogenase 1 (class I)	0.102
Fmo1	flavin containing monooxygenase 1	0.094
Ces1d	carboxylesterase 1D	0.091
Slc25a5	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5	0.089
Acsl1	acyl-CoA synthetase long-chain family member 1	0.085
Prelid1	PRELI domain containing 1	0.080
Inmt	indolethylamine N-methyltransferase	0.079
Gars	glycyl-tRNA synthetase	0.070
Tkt	transketolase	0.067	Yeast
Slc2a1	solute carrier family 2 (facilitated glucose transporter), member 1	0.065
Acly	ATP citrate lyase	0.063
Pgam1	phosphoglycerate mutase 1	0.061	Human
Sepn1	selenoprotein N, 1	0.054
Mpdu1	mannose-P-dolichol utilization defect 1	0.052
Acsl5	acyl-CoA synthetase long-chain family member 5	0.051
Sqle	squalene epoxidase	0.050
Asns	asparagine synthetase	0.047
Scd1	stearoyl-Coenzyme A desaturase 1	0.047
Tuba1b	tubulin, alpha 1B	0.046
Amy1	amylase 1, salivary	0.043
Hp	haptoglobin	0.041
Pon1	paraoxonase 1	0.041
Gsta4	glutathione S-transferase, alpha 4	0.041
Gstm6	glutathione S-transferase, mu 6	0.040
Pnp	purine-nucleoside phosphorylase	0.039
Eif6	eukaryotic translation initiation factor 6	0.037
Pdk3	pyruvate dehydrogenase kinase, isoenzyme 3	0.036
Cd36	CD36 antigen	0.035
Ldlr	low density lipoprotein receptor	0.035
Hsd17b12	hydroxysteroid (17-beta) dehydrogenase 12	0.035
Acat2	acetyl-Coenzyme A acetyltransferase 2	0.035
Plin2	perilipin 2	0.035
Lrrc59	leucine rich repeat containing 59	0.034
Srebf1	sterol regulatory element binding transcription factor 1	0.034
Copz1	coatomer protein complex, subunit zeta 1	0.033
Pgls	6-phosphogluconolactonase	0.033
Cdo1	cysteine dioxygenase 1, cytosolic	0.032
Rbp4	retinol binding protein 4, plasma	0.032
Cs	citrate synthase	0.029
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.029
Cyb5	cytochrome b-5	0.028
Gsr	glutathione reductase	0.028
Akr1c13	aldo-keto reductase family 1, member C13	0.028
Scarb1	scavenger receptor class B, member 1	0.027
Ces2g	carboxylesterase 2G	0.027
Pygl	liver glycogen phosphorylase	0.027
Gstt1	glutathione S-transferase, theta 1	0.026
Hpgd	hydroxyprostaglandin dehydrogenase 15 (NAD)	0.026
Pmvk	phosphomevalonate kinase	0.026
Aox1	aldehyde oxidase 1	0.026
Slc25a1	solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1	0.025
Dhcr7	7-dehydrocholesterol reductase	0.024
Aspa	aspartoacylase	0.024
Ephx2	epoxide hydrolase 2, cytoplasmic	0.024
Pcbd1	pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1	0.023
Lss	lanosterol synthase	0.023
Cyp51	cytochrome P450, family 51	0.022
Rnpep	arginyl aminopeptidase (aminopeptidase B)	0.022
Agmo	alkylglycerol monooxygenase	0.022
Cyp2d22	cytochrome P450, family 2, subfamily d, polypeptide 22	0.022
Sfxn1	sideroflexin 1	0.022
Ephx1	epoxide hydrolase 1, microsomal	0.021
Slc16a7	solute carrier family 16 (monocarboxylic acid transporters), member 7	0.021
Fah	fumarylacetoacetate hydrolase	0.021
Apoe	apolipoprotein E	0.021
Alas1	aminolevulinic acid synthase 1	0.020
Sirt3	sirtuin 3 (silent mating type information regulation 2, homolog) 3 (S. cerevisiae)	0.020
Xdh	xanthine dehydrogenase	0.020
Sepp1	selenoprotein P, plasma, 1	0.020
Psat1	phosphoserine aminotransferase 1	0.020
Thrsp	thyroid hormone responsive SPOT14 homolog (Rattus)	0.019
Ugt1a1	UDP glucuronosyltransferase 1 family, polypeptide A1	0.019
Xpnpep1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.018
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.018
Aacs	acetoacetyl-CoA synthetase	0.018
Sc4mol	sterol-C4-methyl oxidase-like	0.018
Pcx	pyruvate carboxylase	0.017
Ces1e	carboxylesterase 1E	0.017
Idi1	isopentenyl-diphosphate delta isomerase	0.017
Selenbp1	selenium binding protein 1	0.017
Abhd5	abhydrolase domain containing 5	0.017
Acat3	acetyl-Coenzyme A acetyltransferase 3	0.017
Pnp2	purine-nucleoside phosphorylase 2	0.017
Por	P450 (cytochrome) oxidoreductase	0.017
Sult1d1	sulfotransferase family 1D, member 1	0.017
Tspo	translocator protein	0.016
Dhrs7	dehydrogenase/reductase (SDR family) member 7	0.016
9030617O03Rik	RIKEN cDNA 9030617O03 gene	0.016
Tmbim6	transmembrane BAX inhibitor motif containing 6	0.016
Sigmar1	sigma non-opioid intracellular receptor 1	0.016
Pxmp2	peroxisomal membrane protein 2	0.016
Clu	clusterin	0.016
Tmem56	transmembrane protein 56	0.016
Tst	thiosulfate sulfurtransferase, mitochondrial	0.016
Pfkp	phosphofructokinase, platelet	0.015
Hsd17b11	hydroxysteroid (17-beta) dehydrogenase 11	0.015
Msra	methionine sulfoxide reductase A	0.015
Gstm2	glutathione S-transferase, mu 2	0.015
Prdx6	peroxiredoxin 6	0.015
Klf15	Kruppel-like factor 15	0.015
Adipor2	adiponectin receptor 2	0.015
Elovl6	ELOVL family member 6, elongation of long chain fatty acids (yeast)	0.015
Aldh2	aldehyde dehydrogenase 2, mitochondrial	0.015	Yeast
Reep6	receptor accessory protein 6	0.015
Papss2	3'-phosphoadenosine 5'-phosphosulfate synthase 2	0.015
Gsto1	glutathione S-transferase omega 1	0.014
Ivd	isovaleryl coenzyme A dehydrogenase	0.014
Cndp2	CNDP dipeptidase 2 (metallopeptidase M20 family)	0.014
Slc9a3r1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.014
Wdr81	WD repeat domain 81	0.014
Pon3	paraoxonase 3	0.014
Mgst1	microsomal glutathione S-transferase 1	0.014
Cmbl	carboxymethylenebutenolidase-like (Pseudomonas)	0.014
Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.014
Nadk	NAD kinase	0.014
Cd163	CD163 antigen	0.014
Glrx	glutaredoxin	0.014
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.014
Entpd5	ectonucleoside triphosphate diphosphohydrolase 5	0.014
Cfl1	cofilin 1, non-muscle	0.014
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2	0.014
Slc27a2	solute carrier family 27 (fatty acid transporter), member 2	0.014
Angptl3	angiopoietin-like 3	0.014
Comtd1	catechol-O-methyltransferase domain containing 1	0.014
Dhrs3	dehydrogenase/reductase (SDR family) member 3	0.014
Furin	furin (paired basic amino acid cleaving enzyme)	0.014
Igfbp4	insulin-like growth factor binding protein 4	0.014
Xylb	xylulokinase homolog (H. influenzae)	0.013
Maob	monoamine oxidase B	0.013
Fkbp1a	FK506 binding protein 1a	0.013
Akr1c14	aldo-keto reductase family 1, member C14	0.013
Ces1f	carboxylesterase 1F	0.013
Hnmt	histamine N-methyltransferase	0.013
Cth	cystathionase (cystathionine gamma-lyase)	0.013
Max	Max protein	0.013
Slc46a3	solute carrier family 46, member 3	0.013
Akr1c19	aldo-keto reductase family 1, member C19	0.013
G0s2	G0/G1 switch gene 2	0.012
Mfsd2a	major facilitator superfamily domain containing 2A	0.012
Fabp5	fatty acid binding protein 5, epidermal	0.012
Hk2	hexokinase 2	0.012
Alad	aminolevulinate, delta-, dehydratase	0.012
Adhfe1	alcohol dehydrogenase, iron containing, 1	0.012
Hebp1	heme binding protein 1	0.012
Lass2	LAG1 homolog, ceramide synthase 2	0.012
Vnn1	vanin 1	0.012
Rassf6	Ras association (RalGDS/AF-6) domain family member 6	0.012
Pafah2	platelet-activating factor acetylhydrolase 2	0.012
Lbp	lipopolysaccharide binding protein	0.012
Bbox1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)	0.012
Abhd14b	abhydrolase domain containing 14b	0.012
Shpk	sedoheptulokinase	0.012
Csad	cysteine sulfinic acid decarboxylase	0.012
Gyk	glycerol kinase	0.012
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.012
Ptgr1	prostaglandin reductase 1	0.012
Cyp2r1	cytochrome P450, family 2, subfamily r, polypeptide 1	0.011
Tcn2	transcobalamin 2	0.011
Cpvl	carboxypeptidase, vitellogenic-like	0.011
Cyp4b1	cytochrome P450, family 4, subfamily b, polypeptide 1	0.011
Tbc1d13	TBC1 domain family, member 13	0.011
Akr1c12	aldo-keto reductase family 1, member C12	0.011
Izumo3	IZUMO family member 3	0.011
Gstk1	glutathione S-transferase kappa 1	0.011
Dhcr24	24-dehydrocholesterol reductase	0.011
Dgat2	diacylglycerol O-acyltransferase 2	0.011
Fam63a	family with sequence similarity 63, member A	0.011
Blvrb	biliverdin reductase B (flavin reductase (NADPH))	0.011
Tuba3b	tubulin, alpha 3B	0.011
Pdxk	pyridoxal (pyridoxine, vitamin B6) kinase	0.011
Comt	catechol-O-methyltransferase	0.011
Mgam	maltase-glucoamylase	0.011
Slc25a13	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13	0.011
Gclm	glutamate-cysteine ligase, modifier subunit	0.011
Sephs2	selenophosphate synthetase 2	0.011
Mpzl2	myelin protein zero-like 2	0.011
Sdr42e1	short chain dehydrogenase/reductase family 42E, member 1	0.011
Abcc3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	0.011
Hmgcs1	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1	0.011
Acp5	acid phosphatase 5, tartrate resistant	0.011
Dgat1	diacylglycerol O-acyltransferase 1	0.011
Aars	alanyl-tRNA synthetase	0.011
Acss2	acyl-CoA synthetase short-chain family member 2	0.011
Rsc1a1	regulatory solute carrier protein, family 1, member 1	0.011
Mvd	mevalonate (diphospho) decarboxylase	0.011
1700012B09Rik	RIKEN cDNA 1700012B09 gene	0.011
Tesk2	testis-specific kinase 2	0.010
Fam82a2	family with sequence similarity 82, member A2	0.010
Aox3	aldehyde oxidase 3	0.010
Cyb5b	cytochrome b5 type B	0.010
Fam151b	family with sequence similarity 151, member B	0.010
Asl	argininosuccinate lyase	0.010
Sec16b	SEC16 homolog B (S. cerevisiae)	0.010
Hacl1	2-hydroxyacyl-CoA lyase 1	0.010
Cyb5r3	cytochrome b5 reductase 3	0.010
Snapc5	small nuclear RNA activating complex, polypeptide 5	0.010
Mocos	molybdenum cofactor sulfurase	0.010
Aldh1b1	aldehyde dehydrogenase 1 family, member B1	0.010	Yeast
Aass	aminoadipate-semialdehyde synthase	0.010
1110038D17Rik	RIKEN cDNA 1110038D17 gene	0.010