IMP

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Mus musculus

2 genes annotated in mouse

Multi-species View

positive regulation of glutamate secretion

GO:0014049

Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of glutamate secretion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of glutamate secretion" (in gray)

Name	Description	Probability	Func Analog Organism
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	1.000
Dlg4	discs, large homolog 4 (Drosophila)	0.899
Mll1	myeloid/lymphoid or mixed-lineage leukemia 1	0.338
Grm1	glutamate receptor, metabotropic 1	0.320
Drd2	dopamine receptor D2	0.171
Gnrh1	gonadotropin releasing hormone 1	0.162
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.137
Atxn1	ataxin 1	0.126
Gabbr2	gamma-aminobutyric acid (GABA) B receptor, 2	0.124
Plcb1	phospholipase C, beta 1	0.122
Plcg1	phospholipase C, gamma 1	0.119
Nos1	nitric oxide synthase 1, neuronal	0.119
Nf1	neurofibromatosis 1	0.115
Dnm1	dynamin 1	0.113
P2rx2	purinergic receptor P2X, ligand-gated ion channel, 2	0.112	Mouse
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.093
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.089
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.084
App	amyloid beta (A4) precursor protein	0.080
Ptgir	prostaglandin I receptor (IP)	0.077
Tgfb1	transforming growth factor, beta 1	0.070
Adam17	a disintegrin and metallopeptidase domain 17	0.068
Gata1	GATA binding protein 1	0.065
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.062
Epas1	endothelial PAS domain protein 1	0.058
Emx1	empty spiracles homolog 1 (Drosophila)	0.056
P2rx3	purinergic receptor P2X, ligand-gated ion channel, 3	0.055	Mouse
Nt5e	5' nucleotidase, ecto	0.052
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.051
Crhr1	corticotropin releasing hormone receptor 1	0.049
Prkcc	protein kinase C, gamma	0.047
Kif1b	kinesin family member 1B	0.045
Cit	citron	0.040
Crmp1	collapsin response mediator protein 1	0.037
Apln	apelin	0.037
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.036
Tmed8	transmembrane emp24 domain containing 8	0.035
Trpm5	transient receptor potential cation channel, subfamily M, member 5	0.035
Braf	Braf transforming gene	0.034
Inpp4a	inositol polyphosphate-4-phosphatase, type I	0.034
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.033
Shank3	SH3/ankyrin domain gene 3	0.030
Snx13	sorting nexin 13	0.030
Spert	spermatid associated	0.030
Mtap2	microtubule-associated protein 2	0.028
Prkce	protein kinase C, epsilon	0.028
Sntb1	syntrophin, basic 1	0.028
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.028
Hif1a	hypoxia inducible factor 1, alpha subunit	0.028
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.027
Fut7	fucosyltransferase 7	0.027
Egfr	epidermal growth factor receptor	0.027
Tspyl1	testis-specific protein, Y-encoded-like 1	0.026
Rasgrp1	RAS guanyl releasing protein 1	0.026
Sstr3	somatostatin receptor 3	0.026
Klhl24	kelch-like 24 (Drosophila)	0.025
Socs5	suppressor of cytokine signaling 5	0.024
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.024
Plxna1	plexin A1	0.024
Gjc2	gap junction protein, gamma 2	0.024
Sdc3	syndecan 3	0.023
Prkcb	protein kinase C, beta	0.023
1810065E05Rik	RIKEN cDNA 1810065E05 gene	0.023
Il6st	interleukin 6 signal transducer	0.022
Apoe	apolipoprotein E	0.022
Cela2a	chymotrypsin-like elastase family, member 2A	0.022
Hif3a	hypoxia inducible factor 3, alpha subunit	0.022
Vav2	vav 2 oncogene	0.022
Clock	circadian locomotor output cycles kaput	0.021
Phf1	PHD finger protein 1	0.021
Slc39a5	solute carrier family 39 (metal ion transporter), member 5	0.021
Grin2d	glutamate receptor, ionotropic, NMDA2D (epsilon 4)	0.021
Adam23	a disintegrin and metallopeptidase domain 23	0.021
Slc23a2	solute carrier family 23 (nucleobase transporters), member 2	0.021
Sstr2	somatostatin receptor 2	0.021
Aatk	apoptosis-associated tyrosine kinase	0.020
Mtl5	metallothionein-like 5, testis-specific (tesmin)	0.020
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.020
Dnajb8	DnaJ (Hsp40) homolog, subfamily B, member 8	0.020
Lyl1	lymphoblastomic leukemia 1	0.020
Arhgef2	rho/rac guanine nucleotide exchange factor (GEF) 2	0.019
a	nonagouti	0.019
Gcgr	glucagon receptor	0.019
Cel	carboxyl ester lipase	0.019
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.018
Tapbp	TAP binding protein	0.018
Cd38	CD38 antigen	0.018
Pax4	paired box gene 4	0.018
Il10rb	interleukin 10 receptor, beta	0.018
Arc	activity regulated cytoskeletal-associated protein	0.018
Shank2	SH3/ankyrin domain gene 2	0.018
Il10ra	interleukin 10 receptor, alpha	0.018
Mageb3	melanoma antigen, family B, 3	0.018
Atp8a1	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	0.017
Kcnh3	potassium voltage-gated channel, subfamily H (eag-related), member 3	0.017
Tlr9	toll-like receptor 9	0.017
Odf3	outer dense fiber of sperm tails 3	0.017
Atp6v1e2	ATPase, H+ transporting, lysosomal V1 subunit E2	0.017
Pklr	pyruvate kinase liver and red blood cell	0.017
Nags	N-acetylglutamate synthase	0.017
Pdzk1ip1	PDZK1 interacting protein 1	0.016
Prnp	prion protein	0.016
2310002J15Rik	RIKEN cDNA 2310002J15 gene	0.016
Camk2b	calcium/calmodulin-dependent protein kinase II, beta	0.016
Msgn1	mesogenin 1	0.016
Vegfa	vascular endothelial growth factor A	0.016
1700012B07Rik	RIKEN cDNA 1700012B07 gene	0.016
Abcg8	ATP-binding cassette, sub-family G (WHITE), member 8	0.016
Wnt2b	wingless related MMTV integration site 2b	0.016
Ptgfrn	prostaglandin F2 receptor negative regulator	0.016
Dbh	dopamine beta hydroxylase	0.016
Elf4	E74-like factor 4 (ets domain transcription factor)	0.015
Actl7b	actin-like 7b	0.015
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.015
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.015
Mylk2	myosin, light polypeptide kinase 2, skeletal muscle	0.015
Cx3cr1	chemokine (C-X3-C) receptor 1	0.015
Smc1b	structural maintenance of chromosomes 1B	0.015
S1pr3	sphingosine-1-phosphate receptor 3	0.015
Ncoa1	nuclear receptor coactivator 1	0.015
Kcna6	potassium voltage-gated channel, shaker-related, subfamily, member 6	0.014
Rasgrp2	RAS, guanyl releasing protein 2	0.014
Chst3	carbohydrate (chondroitin 6/keratan) sulfotransferase 3	0.014
Krtap5-1	keratin associated protein 5-1	0.014
Ngp	neutrophilic granule protein	0.014
Gna15	guanine nucleotide binding protein, alpha 15	0.014
F7	coagulation factor VII	0.014
Ucn	urocortin	0.013
Padi4	peptidyl arginine deiminase, type IV	0.013
Amh	anti-Mullerian hormone	0.013
Vav3	vav 3 oncogene	0.013
Klc2	kinesin light chain 2	0.013
Ccdc48	coiled-coil domain containing 48	0.013
Ctrb1	chymotrypsinogen B1	0.013
1700014N06Rik	RIKEN cDNA 1700014N06 gene	0.013
Tac4	tachykinin 4	0.013
Aplp2	amyloid beta (A4) precursor-like protein 2	0.013
Mettl7a1	methyltransferase like 7A1	0.013
4933412E24Rik	RIKEN cDNA 4933412E24 gene	0.013
Gab2	growth factor receptor bound protein 2-associated protein 2	0.013
Pzp	pregnancy zone protein	0.013
Cttn	cortactin	0.013
Atp1b2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.013
Galr3	galanin receptor 3	0.013
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.013
Ids	iduronate 2-sulfatase	0.013
Ghrl	ghrelin	0.013
Il13	interleukin 13	0.013
Spry4	sprouty homolog 4 (Drosophila)	0.012
Tbx6	T-box 6	0.012
Slc8a2	solute carrier family 8 (sodium/calcium exchanger), member 2	0.012
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.012
Fgf22	fibroblast growth factor 22	0.012
Pten	phosphatase and tensin homolog	0.012
Zfp865	zinc finger protein 865	0.012
Sh3pxd2a	SH3 and PX domains 2A	0.012
Ypel3	yippee-like 3 (Drosophila)	0.012
Sntb2	syntrophin, basic 2	0.012
Homer1	homer homolog 1 (Drosophila)	0.012
S1pr1	sphingosine-1-phosphate receptor 1	0.012
Itgax	integrin alpha X	0.012
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.012
Smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.012
Lgmn	legumain	0.012
Foxd2	forkhead box D2	0.012
Gpr27	G protein-coupled receptor 27	0.012
Vpreb2	pre-B lymphocyte gene 2	0.012
Syn2	synapsin II	0.012
Mbd3l1	methyl-CpG binding domain protein 3-like 1	0.012
Ptafr	platelet-activating factor receptor	0.012
Apba1	amyloid beta (A4) precursor protein binding, family A, member 1	0.011
Arnt	aryl hydrocarbon receptor nuclear translocator	0.011
Gfi1b	growth factor independent 1B	0.011
Tcte1	t-complex-associated testis expressed 1	0.011
4933406J08Rik	RIKEN cDNA 4933406J08 gene	0.011
Numbl	numb-like	0.011
Tdrd1	tudor domain containing 1	0.011
Hgfac	hepatocyte growth factor activator	0.011
Wrn	Werner syndrome homolog (human)	0.011
Rab37	RAB37, member of RAS oncogene family	0.011
Sh2d1b1	SH2 domain protein 1B1	0.011
Snn	stannin	0.011
Shank1	SH3/ankyrin domain gene 1	0.011
6030468B19Rik	RIKEN cDNA 6030468B19 gene	0.011
Fam187a	family with sequence similarity 187, member A	0.011
Slc24a6	solute carrier family 24 (sodium/potassium/calcium exchanger), member 6	0.011
Tlx2	T-cell leukemia, homeobox 2	0.011
Pde3a	phosphodiesterase 3A, cGMP inhibited	0.011
Gm13275	predicted gene 13275	0.011
Camk4	calcium/calmodulin-dependent protein kinase IV	0.011
Il12b	interleukin 12b	0.011
Dlg2	discs, large homolog 2 (Drosophila)	0.011
Irf5	interferon regulatory factor 5	0.010
Insr	insulin receptor	0.010
1700001K19Rik	RIKEN cDNA 1700001K19 gene	0.010
Tgfbr3	transforming growth factor, beta receptor III	0.010
Ar	androgen receptor	0.010
Epb4.1l2	erythrocyte protein band 4.1-like 2	0.010
Rab3il1	RAB3A interacting protein (rabin3)-like 1	0.010
Arf2	ADP-ribosylation factor 2	0.010
Folr2	folate receptor 2 (fetal)	0.010
Figla	folliculogenesis specific basic helix-loop-helix	0.010
Myo9a	myosin IXa	0.010
Sstr4	somatostatin receptor 4	0.010
Adcy6	adenylate cyclase 6	0.010
Timp2	tissue inhibitor of metalloproteinase 2	0.010
Cldn13	claudin 13	0.010
Ppyr1	pancreatic polypeptide receptor 1	0.010