IMP
Process View
negative regulation of immune response to tumor cell
Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune response to tumor cell.
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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of immune response to tumor cell"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Klrd1 | killer cell lectin-like receptor, subfamily D, member 1 | 0.944 | ||
| Klra5 | killer cell lectin-like receptor, subfamily A, member 5 | 0.933 | Rat | |
| Gzmb | granzyme B | 0.855 | ||
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.709 | ||
| Xcl1 | chemokine (C motif) ligand 1 | 0.643 | ||
| Nkg7 | natural killer cell group 7 sequence | 0.411 | ||
| Klrk1 | killer cell lectin-like receptor subfamily K, member 1 | 0.358 | Rat | |
| Reg3g | regenerating islet-derived 3 gamma | 0.351 | ||
| Gzmk | granzyme K | 0.345 | ||
| Il7r | interleukin 7 receptor | 0.327 | ||
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.312 | ||
| Mmp12 | matrix metallopeptidase 12 | 0.302 | ||
| Sell | selectin L | 0.295 | ||
| Rgs1 | regulator of G-protein signaling 1 | 0.175 | ||
| Prf1 | perforin 1 (pore forming protein) | 0.173 | ||
| Tlr7 | toll-like receptor 7 | 0.167 | ||
| Cd2 | Cd2 molecule | 0.150 | ||
| Tcrb | T-cell receptor beta chain | 0.149 | ||
| Slc13a1 | solute carrier family 13 (sodium/sulfate symporters), member 1 | 0.144 | ||
| LOC300024 | similar to Ly6-B antigen gene | 0.143 | ||
| Klrc2 | killer cell lectin-like receptor subfamily C, member 2 | 0.141 | Rat | |
| Samsn1 | SAM domain, SH3 domain and nuclear localization signals, 1 | 0.136 | ||
| Igsf6 | immunoglobulin superfamily, member 6 | 0.135 | ||
| Gzmm | granzyme M (lymphocyte met-ase 1) | 0.135 | ||
| Ifng | interferon gamma | 0.134 | ||
| Ccr5 | chemokine (C-C motif) receptor 5 | 0.114 | ||
| St8sia4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 | 0.106 | ||
| Cyp2c12 | cytochrome P450, family 2, subfamily c, polypeptide 12 | 0.103 | ||
| Cd8a | CD8a molecule | 0.098 | ||
| Slamf9 | SLAM family member 9 | 0.098 | ||
| Slc9a4 | solute carrier family 9 (sodium/hydrogen exchanger), member 4 | 0.097 | ||
| Serpinb3a | serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A | 0.093 | ||
| Mcpt8 | mast cell protease 8 | 0.092 | ||
| Lilrb3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 | 0.085 | ||
| Klra17 | killer cell lectin-like receptor, subfamily A, member 17 | 0.085 | ||
| Clec12a | C-type lectin domain family 12, member A | 0.083 | ||
| Il10ra | interleukin 10 receptor, alpha | 0.083 | ||
| Vom1r93 | vomeronasal 1 receptor 93 | 0.080 | ||
| Zap70 | zeta-chain (TCR) associated protein kinase | 0.078 | ||
| Pcsk1 | proprotein convertase subtilisin/kexin type 1 | 0.070 | ||
| Slpi | secretory leukocyte peptidase inhibitor | 0.069 | ||
| Tnf | tumor necrosis factor (TNF superfamily, member 2) | 0.068 | ||
| Il1rl1 | interleukin 1 receptor-like 1 | 0.068 | ||
| Ccl5 | chemokine (C-C motif) ligand 5 | 0.067 | ||
| Acap1 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 | 0.065 | ||
| Klrb1a | killer cell lectin-like receptor subfamily B, member 1A | 0.064 | ||
| Olr1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.064 | Rat | |
| Sit1 | signaling threshold regulating transmembrane adaptor 1 | 0.064 | ||
| Gpr114 | G protein-coupled receptor 114 | 0.063 | ||
| Lilrb4 | leukocyte immunoglobulin-like receptor, subfamily B, member 4 | 0.063 | ||
| Ubd | ubiquitin D | 0.062 | ||
| P2ry14 | purinergic receptor P2Y, G-protein coupled, 14 | 0.060 | ||
| Ccl9 | chemokine (C-C motif) ligand 9 | 0.059 | ||
| Cd247 | Cd247 molecule | 0.056 | ||
| Tnni3k | TNNI3 interacting kinase | 0.056 | ||
| Cd72 | Cd72 molecule | 0.055 | ||
| Scin | scinderin | 0.053 | ||
| Oas1b | 2-5 oligoadenylate synthetase 1B | 0.051 | ||
| Serpine1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.049 | ||
| Clec9a | C-type lectin domain family 9, member a | 0.048 | Rat | |
| Map3k8 | mitogen-activated protein kinase kinase kinase 8 | 0.045 | ||
| Spn | sialophorin | 0.044 | ||
| Oprm1 | opioid receptor, mu 1 | 0.044 | ||
| Ccl19 | chemokine (C-C motif) ligand 19 | 0.044 | ||
| Skap1 | src kinase associated phosphoprotein 1 | 0.043 | ||
| Fam65b | family with sequence similarity 65, member B | 0.043 | ||
| Cxcl10 | chemokine (C-X-C motif) ligand 10 | 0.042 | ||
| Il1b | interleukin 1 beta | 0.042 | ||
| Gpx2 | glutathione peroxidase 2 | 0.041 | ||
| Cd22 | CD22 molecule | 0.040 | ||
| Vom1r102 | vomeronasal 1 receptor 102 | 0.039 | ||
| Rgs14 | regulator of G-protein signaling 14 | 0.038 | ||
| LOC100362325 | rCG28200-like | 0.038 | ||
| Adrbk2 | adrenergic, beta, receptor kinase 2 | 0.037 | ||
| Il6 | interleukin 6 | 0.036 | ||
| Il1rn | interleukin 1 receptor antagonist | 0.036 | ||
| Prl2b1 | Prolactin family 2, subfamily b, member 1 | 0.035 | ||
| Atp6v1g3 | ATPase, H+ transporting, lysosomal V1 subunit G3 | 0.035 | ||
| Cd3g | CD3 molecule, gamma | 0.034 | ||
| Gucy2g | guanylate cyclase 2G | 0.034 | ||
| Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.034 | ||
| Il18r1 | interleukin 18 receptor 1 | 0.034 | ||
| S100vp | S100 calcium-binding protein, ventral prostate | 0.033 | ||
| Olr1226 | olfactory receptor 1226 | 0.031 | ||
| Cyp2c13 | cytochrome P450, family 2, subfamily c, polypeptide 13 | 0.031 | ||
| Epsti1 | epithelial stromal interaction 1 (breast) | 0.031 | ||
| Cd69 | Cd69 molecule | 0.031 | Rat | |
| Cd86 | CD86 molecule | 0.031 | ||
| Mcpt3 | mast cell peptidase 3 | 0.030 | ||
| Serpinb2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.030 | ||
| Ctsj | cathepsin J | 0.030 | ||
| Sprr1b | small proline-rich protein 1B (cornifin) | 0.029 | ||
| LOC24906 | RoBo-1 | 0.029 | ||
| Neurl3 | neuralized homolog 3 (Drosophila) | 0.029 | ||
| Si | sucrase-isomaltase (alpha-glucosidase) | 0.028 | ||
| Mcpt4 | mast cell protease 4 | 0.028 | ||
| Reg3b | regenerating islet-derived 3 beta | 0.028 | ||
| Krtap13-2 | keratin associated protein 13-2 | 0.027 | ||
| Cd244 | Cd244 molecule, natural killer cell receptor 2B4 | 0.027 | ||
| Cst7 | cystatin F (leukocystatin) | 0.026 | ||
| Ccl3 | chemokine (C-C motif) ligand 3 | 0.026 | ||
| Stfa2l3 | stefin A2-like 3 | 0.026 | ||
| Mageb16 | melanoma antigen family B, 16 | 0.026 | ||
| Tnfrsf14 | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) | 0.025 | ||
| Slfn3 | schlafen 3 | 0.025 | ||
| Sh2d1a | SH2 domain protein 1A | 0.025 | ||
| Klrc1 | killer cell lectin-like receptor subfamily C, member 1 | 0.025 | Rat | |
| Clec7a | C-type lectin domain family 7, member a | 0.025 | Rat | |
| Fcer1a | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.024 | ||
| Tas2r105 | taste receptor, type 2, member 105 | 0.024 | ||
| Sh2d2a | SH2 domain protein 2A | 0.024 | ||
| Art2 | ADP-ribosyltransferase 2 | 0.024 | ||
| Phemx | pan hematopoietic expression | 0.023 | ||
| Inpp4b | inositol polyphosphate-4-phosphatase, type II | 0.023 | ||
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.022 | ||
| Zcwpw1 | zinc finger, CW-type with PWWP domain 1 | 0.022 | ||
| Nr4a3 | nuclear receptor subfamily 4, group A, member 3 | 0.022 | ||
| Crct1 | cysteine-rich C-terminal 1 | 0.021 | ||
| Arid5a | AT rich interactive domain 5A (Mrf1 like) | 0.021 | ||
| RGD1311300 | similar to T cell receptor V delta 6 | 0.021 | ||
| Smcp | sperm mitochondria-associated cysteine-rich protein | 0.021 | ||
| Ch25h | cholesterol 25-hydroxylase | 0.021 | ||
| Expi | extracellular proteinase inhibitor | 0.020 | ||
| Vom1r101 | vomeronasal 1 receptor 101 | 0.020 | ||
| Hcls1 | hematopoietic cell specific Lyn substrate 1 | 0.020 | ||
| Cxcl11 | chemokine (C-X-C motif) ligand 11 | 0.020 | ||
| Igfl3 | IGF-like family member 3 | 0.020 | ||
| Gzma | granzyme A | 0.020 | ||
| Mos | Moloney sarcoma oncogene | 0.020 | ||
| Plek2 | pleckstrin 2 | 0.019 | ||
| Prkag3 | protein kinase, AMP-activated, gamma 3 non-catalytic subunit | 0.019 | ||
| Fcgr1a | Fc fragment of IgG, high affinity Ia, receptor (CD64) | 0.019 | ||
| RGD1562844 | similar to serine (or cysteine) proteinase inhibitor, clade B, member 9 | 0.019 | ||
| Itgb2 | integrin, beta 2 | 0.019 | ||
| Spic | Spi-C transcription factor (Spi-1/PU.1 related) | 0.019 | ||
| Klre1 | killer cell lectin-like receptor, family E, member 1 | 0.018 | ||
| Gimap4 | GTPase, IMAP family member 4 | 0.018 | ||
| Gfra3 | GDNF family receptor alpha 3 | 0.018 | ||
| Cxcl1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.018 | ||
| Prl2a1 | Prolactin family 2, subfamily a, member 1 | 0.018 | ||
| Nenf | neuron derived neurotrophic factor | 0.018 | ||
| Myocd | myocardin | 0.018 | ||
| Csn1s1 | casein alpha s1 | 0.018 | ||
| Ms4a8a | membrane-spanning 4-domains, subfamily A, member 8A | 0.018 | ||
| Mbnl3 | muscleblind-like 3 (Drosophila) | 0.017 | ||
| Cd7 | Cd7 molecule | 0.017 | ||
| Ugt2a1 | UDP glucuronosyltransferase 2 family, polypeptide A1 | 0.017 | ||
| Klra22 | killer cell lectin-like receptor subfamily A, member 22 | 0.017 | Rat | |
| Chrm5 | cholinergic receptor, muscarinic 5 | 0.016 | ||
| Gem | GTP binding protein (gene overexpressed in skeletal muscle) | 0.016 | ||
| Vcsa2 | variable coding sequence A2 | 0.016 | ||
| Prl8a7 | prolactin family 8, subfamily a, member 7 | 0.016 | ||
| Fas | Fas (TNF receptor superfamily, member 6) | 0.016 | ||
| Irf2 | interferon regulatory factor 2 | 0.016 | ||
| Sdr16c5 | short chain dehydrogenase/reductase family 16C, member 5 | 0.016 | ||
| Arhgap4 | Rho GTPase activating protein 4 | 0.016 | ||
| Gucy2d | guanylate cyclase 2d | 0.016 | ||
| Olr1697 | olfactory receptor 1697 | 0.016 | ||
| Olr59 | olfactory receptor 59 | 0.016 | ||
| Cyp7b1 | cytochrome P450, family 7, subfamily b, polypeptide 1 | 0.016 | ||
| Fcgr3a | Fc fragment of IgG, low affinity IIIa, receptor | 0.016 | ||
| Il2rb | interleukin 2 receptor, beta | 0.015 | ||
| RGD1566368 | similar to Solute carrier family 6 (neurotransmitter transporter), member 20 | 0.015 | ||
| Stx11 | syntaxin 11 | 0.015 | ||
| Cyp3a2 | cytochrome P450, family 3, subfamily a, polypeptide 2 | 0.015 | ||
| Pvrl4 | poliovirus receptor-related 4 | 0.015 | ||
| Lrrc8c | leucine rich repeat containing 8 family, member C | 0.015 | ||
| Parvg | parvin, gamma | 0.015 | ||
| Tmem182 | transmembrane protein 182 | 0.014 | ||
| Slc22a25 | solute carrier family 22, member 25 | 0.014 | ||
| Gimap6 | GTPase, IMAP family member 6 | 0.014 | ||
| RGD1304644 | similar to RIKEN cDNA 2310046K01 | 0.014 | ||
| Stab2 | stabilin 2 | 0.014 | ||
| C7 | complement component 7 | 0.014 | ||
| Lepr | leptin receptor | 0.014 | ||
| Stk36 | serine/threonine kinase 36 (fused homolog, Drosophila) | 0.014 | ||
| Ms4a7 | membrane-spanning 4-domains, subfamily A, member 7 | 0.014 | ||
| Slc8a1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.014 | ||
| Clec4f | C-type lectin domain family 4, member f | 0.014 | ||
| Pax8 | paired box 8 | 0.014 | ||
| Il27ra | interleukin 27 receptor, alpha | 0.014 | ||
| F2rl1 | coagulation factor II (thrombin) receptor-like 1 | 0.014 | ||
| Txk | TXK tyrosine kinase | 0.013 | ||
| Sycp1 | synaptonemal complex protein 1 | 0.013 | ||
| Unc5cl | unc-5 homolog C (C. elegans)-like | 0.013 | ||
| Olr1530 | olfactory receptor 1530 | 0.013 | ||
| Ttk | Ttk protein kinase | 0.013 | ||
| Rhoh | ras homolog gene family, member H | 0.013 | ||
| Panx3 | pannexin 3 | 0.013 | ||
| Ms4a2 | membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) | 0.013 | ||
| Angptl1 | angiopoietin-like 1 | 0.013 | ||
| LOC690020 | similar to killer cell lectin-like receptor, subfamily A, member 17 | 0.013 | Rat | |
| Scarf1 | scavenger receptor class F, member 1 | 0.013 | ||
| Herc6 | hect domain and RLD 6 | 0.013 | ||
| Ky | kyphoscoliosis peptidase | 0.012 | ||
| LOC363326 | hypothetical LOC363326 | 0.012 | ||
| Myo1f | myosin IF | 0.012 | ||
| Cyp39a1 | cytochrome P450, family 39, subfamily a, polypeptide 1 | 0.012 | ||
| Mcpt1 | mast cell protease 1 | 0.012 | ||
| Ccl21 | chemokine (C-C motif) ligand 21 | 0.012 | ||
| Mmp9 | matrix metallopeptidase 9 | 0.012 | ||
| Dmbt1 | deleted in malignant brain tumors 1 | 0.012 | ||
| Snai2 | snail homolog 2 (Drosophila) | 0.011 | ||
| Vom1r90 | vomeronasal 1 receptor 90 | 0.011 | ||
| Oasl | 2'-5'-oligoadenylate synthetase-like | 0.011 | ||
| Dok2 | docking protein 2 | 0.011 | ||
| LOC100361765 | homeobox B2 | 0.011 | ||
| Plcg2 | phospholipase C, gamma 2 | 0.011 | ||
| Cnr2 | cannabinoid receptor 2 (macrophage) | 0.011 | ||
| LOC494538 | ABP beta | 0.011 | ||
| Duoxa1 | dual oxidase maturation factor 1 | 0.011 | ||
| Creb3l3 | cAMP responsive element binding protein 3-like 3 | 0.011 | ||
| Olr1504 | olfactory receptor 1504 | 0.011 | ||
| Gpr64 | G protein-coupled receptor 64 | 0.011 | ||
| Phex | phosphate regulating endopeptidase homolog, X-linked | 0.011 | ||
| Sval2 | seminal vesicle antigen-like 2 | 0.011 | ||
| LOC100361053 | mCG1039741-like | 0.011 | ||
| Col4a3 | collagen, type IV, alpha 3 | 0.011 | ||
| Card6 | caspase recruitment domain family, member 6 | 0.011 | ||
| Faslg | Fas ligand (TNF superfamily, member 6) | 0.011 | ||
| Arhgap15 | Rho GTPase activating protein 15 | 0.011 | ||
| Capn6 | calpain 6 | 0.011 | ||
| Plin5 | perilipin 5 | 0.011 | ||
| Stap1 | signal transducing adaptor family member 1 | 0.011 | ||
| Cpb1 | carboxypeptidase B1 (tissue) | 0.010 | ||
| Myct1 | myc target 1 | 0.010 | ||
| Slc6a12 | solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 | 0.010 | ||
| Scel | sciellin | 0.010 | ||
| Erg | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 0.010 | ||
| Gen1 | Gen homolog 1, endonuclease (Drosophila) | 0.010 | ||
| LOC685527 | hypothetical protein LOC685527 | 0.010 | ||
| Pla2g2d | phospholipase A2, group IID | 0.010 | ||
| Cldn7 | claudin 7 | 0.010 | ||
| Lnpep | leucyl/cystinyl aminopeptidase | 0.010 | ||
| Ly49si1 | immunoreceptor Ly49si1 | 0.010 | Rat | |
| Sp100 | SP100 nuclear antigen | 0.010 |