IMP

Process View

Rattus norvegicus

29 genes annotated in rat

regulation of sensory perception of pain

GO:0051930

Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of sensory perception of pain"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of sensory perception of pain" (in gray)

Name	Description	Probability	Func Analog Organism
Hbb	hemoglobin, beta	0.504
LOC287167	globin, alpha	0.278	Rat
Alas2	aminolevulinate, delta-, synthase 2	0.260
LOC100134871	beta globin minor gene	0.222
LOC689064	beta-globin	0.222
Nmbr	neuromedin B receptor	0.109
Hba-a2	hemoglobin alpha, adult chain 2	0.107
Shank2	SH3 and multiple ankyrin repeat domains 2	0.089
Gzmk	granzyme K	0.079
Kcnj16	potassium inwardly-rectifying channel, subfamily J, member 16	0.077	Rat
Pnliprp2	pancreatic lipase-related protein 2	0.076
Olr1500	olfactory receptor 1500	0.076
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.074
Kcnc2	potassium voltage gated channel, Shaw-related subfamily, member 2	0.073
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.072
Oprk1	opioid receptor, kappa 1	0.069	Rat
Fcgr1a	Fc fragment of IgG, high affinity Ia, receptor (CD64)	0.065	Rat
Olr226	olfactory receptor 226	0.062
Npy5r	neuropeptide Y receptor Y5	0.062	Rat
Kcna3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.057
Il1a	interleukin 1 alpha	0.056
Hbb-b1	hemoglobin, beta adult major chain	0.054
Cxcl6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.054
Kcnk1	potassium channel, subfamily K, member 1	0.051
Msx2	msh homeobox 2	0.050
Fgf14	fibroblast growth factor 14	0.049
Hes2	hairy and enhancer of split 2 (Drosophila)	0.048
Gpr83	G protein-coupled receptor 83	0.047	Rat
Egr3	early growth response 3	0.046
Ar	androgen receptor	0.045
Slc18a2	solute carrier family 18 (vesicular monoamine), member 2	0.044
Slc8a2	solute carrier family 8 (sodium/calcium exchanger), member 2	0.044
Cx3cr1	chemokine (C-X3-C motif) receptor 1	0.043
Csf3	colony stimulating factor 3 (granulocyte)	0.042
Fosl1	fos-like antigen 1	0.040
Il1rn	interleukin 1 receptor antagonist	0.040
Insrr	insulin receptor-related receptor	0.040
Mog	myelin oligodendrocyte glycoprotein	0.039
Fat3	FAT tumor suppressor homolog 3 (Drosophila)	0.038
Chrna7	cholinergic receptor, nicotinic, alpha 7	0.038
Gfra2	GDNF family receptor alpha 2	0.038
Cxcl2	chemokine (C-X-C motif) ligand 2	0.038
Scn10a	sodium channel, voltage-gated, type X, alpha subunit	0.038
Galr1	galanin receptor 1	0.036	Rat
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.036	Rat
Ms4a8a	membrane-spanning 4-domains, subfamily A, member 8A	0.036
Scnn1g	sodium channel, nonvoltage-gated 1, gamma	0.035
Phkg1	phosphorylase kinase, gamma 1	0.035
Sstr5	somatostatin receptor 5	0.034	Rat
Kcns2	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2	0.034
Gucy2f	guanylate cyclase 2F	0.034
Ctsj	cathepsin J	0.033
Kcnj4	potassium inwardly-rectifying channel, subfamily J, member 4	0.031
Cdh17	cadherin 17	0.031
Glp1r	glucagon-like peptide 1 receptor	0.031
Mc4r	melanocortin 4 receptor	0.031
Ccl4	chemokine (C-C motif) ligand 4	0.031
Ccr4	chemokine (C-C motif) receptor 4	0.030
Sstr1	somatostatin receptor 1	0.030
Tore	trispanning orphan	0.030
Grin2b	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.030
Tlr2	toll-like receptor 2	0.030	Rat
Adra2c	adrenergic, alpha-2C-, receptor	0.029
Mag	myelin-associated glycoprotein	0.029
Tnfsf4	tumor necrosis factor (ligand) superfamily, member 4	0.029
Chrna1	cholinergic receptor, nicotinic, alpha 1 (muscle)	0.028
Cckar	cholecystokinin A receptor	0.027
Cacng8	calcium channel, voltage-dependent, gamma subunit 8	0.027
Folh1	folate hydrolase 1	0.026
Cd244	Cd244 molecule, natural killer cell receptor 2B4	0.026
Chrna5	cholinergic receptor, nicotinic, alpha 5	0.026
Pvrl4	poliovirus receptor-related 4	0.026
Adam7	ADAM metallopeptidase domain 7	0.026
Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3	0.025
Col10a1	collagen, type X, alpha 1	0.025
Htr5b	5-hydroxytryptamine (serotonin) receptor 5B	0.024	Rat
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.024
Chrna3	cholinergic receptor, nicotinic, alpha 3	0.024
Slc12a1	solute carrier family 12 (sodium/potassium/chloride transporters), member 1	0.024
Mmp13	matrix metallopeptidase 13	0.024
Gabrg1	gamma-aminobutyric acid (GABA) A receptor, gamma 1	0.024
Prl	prolactin	0.024
Ntrk1	neurotrophic tyrosine kinase, receptor, type 1	0.023
Cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.023
Cacng4	calcium channel, voltage-dependent, gamma subunit 4	0.022
Adam2	ADAM metallopeptidase domain 2	0.022
Psg29	pregnancy-specific glycoprotein 29	0.022
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.022
Gpr26	G protein-coupled receptor 26	0.022
Grp	gastrin releasing peptide	0.022
Clec7a	C-type lectin domain family 7, member a	0.021
Tmem163	transmembrane protein 163	0.021
Freq	frequenin homolog (Drosophila)	0.021
Sp3	Sp3 transcription factor	0.021
Syt2	synaptotagmin II	0.021
Gfap	glial fibrillary acidic protein	0.021
Gal	galanin prepropeptide	0.020
Kcng3	potassium voltage-gated channel, subfamily G, member 3	0.020
Ptafr	platelet-activating factor receptor	0.020
Znf483	zinc finger protein 483	0.020
Arhgap23	Rho GTPase activating protein 23	0.020
Homer3	homer homolog 3 (Drosophila)	0.020
Otx1	orthodenticle homeobox 1	0.020
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.020
Calca	calcitonin-related polypeptide alpha	0.020
Psp	parotid secretory protein	0.019
Tcf4	transcription factor 4	0.019
Lrrc7	leucine rich repeat containing 7	0.019
Phox2a	paired-like homeobox 2a	0.019
A3galt2	alpha 1,3-galactosyltransferase 2	0.019
Cartpt	CART prepropeptide	0.019
Rhd	Rh blood group, D antigen	0.019
Clcn1	chloride channel 1	0.019
Prss1	protease, serine, 1 (trypsin 1)	0.019
Ntsr2	neurotensin receptor 2	0.019
Gstm3	glutathione S-transferase mu 3	0.019
Il6	interleukin 6	0.019
Gkn1	gastrokine 1	0.019
Htr2a	5-hydroxytryptamine (serotonin) receptor 2A	0.019	Rat
Mr1	major histocompatibility complex, class I-related	0.019
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.018
Plcd4	phospholipase C, delta 4	0.018
RGD1564664	similar to LOC387763 protein	0.018
Syt8	synaptotagmin VIII	0.018
Unc5b	unc-5 homolog B (C. elegans)	0.018
Gpr88	G-protein coupled receptor 88	0.018
Musk	muscle, skeletal, receptor tyrosine kinase	0.018
Hsd3b5	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5	0.018
Ucp1	uncoupling protein 1 (mitochondrial, proton carrier)	0.018
Csf1	colony stimulating factor 1 (macrophage)	0.018
Iapp	islet amyloid polypeptide	0.018
Olr442	olfactory receptor 442	0.018
Pcdhb12	protocadherin beta 12	0.018
Olr287	olfactory receptor 287	0.018
Edn1	endothelin 1	0.018
Reg3g	regenerating islet-derived 3 gamma	0.018
Ngf	nerve growth factor (beta polypeptide)	0.017
Chp2	calcineurin B homologous protein 2	0.017
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.017
Gja6	gap junction protein, alpha 6	0.017
Plek	pleckstrin	0.017
Gip	gastric inhibitory polypeptide	0.017
Htr1a	5-hydroxytryptamine (serotonin) receptor 1A	0.017	Rat
Pspn	persephin	0.017
Itgam	integrin, alpha M	0.017
Avpr2	arginine vasopressin receptor 2	0.017
Dio2	deiodinase, iodothyronine, type II	0.017
Dhrs9	dehydrogenase/reductase (SDR family) member 9	0.017
Pou3f3	POU class 3 homeobox 3	0.017
Sftpa1	surfactant protein A1	0.017
Hr	hairless	0.017
Ccl20	chemokine (C-C motif) ligand 20	0.017
Alox15	arachidonate 15-lipoxygenase	0.017
Olr1078	olfactory receptor 1078	0.017
Tgm1	transglutaminase 1, K polypeptide	0.017
RGD1564327	similar to integrin alpha 8	0.017
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.016
Tlr4	toll-like receptor 4	0.016
Fshb	follicle stimulating hormone, beta polypeptide	0.016
Chrna6	cholinergic receptor, nicotinic, alpha 6	0.016
Aqp8	aquaporin 8	0.016
Mmp3	matrix metallopeptidase 3	0.016
Mchr1	melanin-concentrating hormone receptor 1	0.016
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.016
Acmsd	aminocarboxymuconate semialdehyde decarboxylase	0.016
Necab1	N-terminal EF-hand calcium binding protein 1	0.016
RGD1561143	similar to cell surface receptor FDFACT	0.016
Cav1	caveolin 1, caveolae protein	0.016
Agtr1a	angiotensin II receptor, type 1a	0.016
Cpb1	carboxypeptidase B1 (tissue)	0.016
Emr1	EGF-like module containing, mucin-like, hormone receptor-like 1	0.016
Pou1f1	POU class 1 homeobox 1	0.016
Si	sucrase-isomaltase (alpha-glucosidase)	0.016
Gcm1	glial cells missing homolog 1 (Drosophila)	0.016
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.016
Cxcl10	chemokine (C-X-C motif) ligand 10	0.015
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.015
Grm1	glutamate receptor, metabotropic 1	0.015	Mouse
Adam5	a disintegrin and metallopeptidase domain 5	0.015
Pde1b	phosphodiesterase 1B, calmodulin-dependent	0.015
Cyp4f1	cytochrome P450, family 4, subfamily f, polypeptide 1	0.015
Htr1b	5-hydroxytryptamine (serotonin) receptor 1B	0.015	Rat
Ccr3	chemokine (C-C motif) receptor 3	0.015
Btc	betacellulin	0.015
Rgs8	regulator of G-protein signaling 8	0.015
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.015
Grpr	gastrin releasing peptide receptor	0.015	Rat
Slc5a5	solute carrier family 5 (sodium iodide symporter), member 5	0.015
Dmrta1	DMRT-like family A1	0.015
Fam148b	family with sequence similarity 148, member B	0.015
Apba1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.015
LOC690358	similar to PR domain containing 11	0.015
Cacng5	calcium channel, voltage-dependent, gamma subunit 5	0.015
Tbx2	T-box 2	0.015
Il1b	interleukin 1 beta	0.015
Strn	striatin, calmodulin binding protein	0.015
Vom2r27	vomeronasal 2 receptor, 27	0.014
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.014
Folr2	folate receptor 2 (fetal)	0.014
Lepr	leptin receptor	0.014
Grid2	glutamate receptor, ionotropic, delta 2	0.014
Aven	apoptosis, caspase activation inhibitor	0.014
Gipr	gastric inhibitory polypeptide receptor	0.014
RGD1559748	similar to Palate lung and nasal carcinoma-like protein precursor (Tongue plunc-like protein)	0.014
Marcks	myristoylated alanine rich protein kinase C substrate	0.014
Kcnv1	potassium channel, subfamily V, member 1	0.014
Cdh6	cadherin 6	0.014
Gjb4	gap junction protein, beta 4	0.014
Psg19	pregnancy specific glycoprotein 19	0.014
Ugt2b7	UDP glucuronosyltransferase 2 family, polypeptide B7	0.014
Pde1c	phosphodiesterase 1C	0.014
Ppyr1	pancreatic polypeptide receptor 1	0.014	Rat
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.014
Eef1a2	eukaryotic translation elongation factor 1 alpha 2	0.014
Slc22a8	solute carrier family 22 (organic anion transporter), member 8	0.014
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.014
Adora3	adenosine A3 receptor	0.014
Slc30a2	solute carrier family 30 (zinc transporter), member 2	0.014
Spam1	sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)	0.014
Gabrd	gamma-aminobutyric acid (GABA) A receptor, delta	0.014
Nxph1	neurexophilin 1	0.014
Tas2r105	taste receptor, type 2, member 105	0.014
Kcnj15	potassium inwardly-rectifying channel, subfamily J, member 15	0.014	Rat
Dgkg	diacylglycerol kinase, gamma	0.014
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.013
Tas2r123	taste receptor, type 2, member 123	0.013
Prok1	prokineticin 1	0.013
RGD1307722	similar to hypothetical protein MGC20700	0.013
Pde3a	phosphodiesterase 3A, cGMP inhibited	0.013
Pax6	paired box 6	0.013
Dusp4	dual specificity phosphatase 4	0.013
Aqp4	aquaporin 4	0.013
Rims1	regulating synaptic membrane exocytosis 1	0.013
Abcc8	ATP-binding cassette, subfamily C (CFTR/MRP), member 8	0.013
Atxn1	ataxin 1	0.013
Mamdc4	MAM domain containing 4	0.013
Hdgfl1	hepatoma derived growth factor-like 1	0.013
Adam3a	ADAM metallopeptidase domain 3A (cyritestin 1)	0.013
Bcan	brevican	0.013
Notch3	Notch homolog 3 (Drosophila)	0.013
Fgb	fibrinogen beta chain	0.013
Uncx	UNC homeobox	0.013
Foxn1	forkhead box N1	0.013
Ncr3	natural cytotoxicity triggering receptor 3	0.013
Lif	leukemia inhibitory factor	0.013
Inhbc	inhibin beta C	0.013
Nrg1	neuregulin 1	0.013
Pmfbp1	polyamine modulated factor 1 binding protein 1	0.013
Casp12	caspase 12	0.013
Olr1496	olfactory receptor 1496	0.013
Calcr	calcitonin receptor	0.013
B3gat1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	0.013
Gper	G protein-coupled estrogen receptor 1	0.013
Grm6	glutamate receptor, metabotropic 6	0.013
Gad2	glutamate decarboxylase 2	0.013
Chrm2	cholinergic receptor, muscarinic 2	0.013
Kcnh7	potassium voltage-gated channel, subfamily H (eag-related), member 7	0.012
Tacr1	tachykinin receptor 1	0.012	Rat
Hes3	hairy and enhancer of split 3 (Drosophila)	0.012
Abcc2	ATP-binding cassette, subfamily C (CFTR/MRP), member 2	0.012
Serpinb2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.012
Slc1a2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.012
Ereg	epiregulin	0.012
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.012
RGD1559532	RGD1559532	0.012
Ehf	ets homologous factor	0.012
Gria1	glutamate receptor, ionotropic, AMPA 1	0.012
Olr416	olfactory receptor 416	0.012
Timp3	TIMP metallopeptidase inhibitor 3	0.012
Cacna1i	calcium channel, voltage-dependent, T type, alpha 1I subunit	0.012
Prp15	proline-rich protein 15	0.012
Ugt8	UDP glycosyltransferase 8	0.012
Duox2	dual oxidase 2	0.012
Il9r	interleukin 9 receptor	0.012
Mmp12	matrix metallopeptidase 12	0.012
Nfasc	neurofascin	0.012
Asph	aspartate-beta-hydroxylase	0.012
Scn1b	sodium channel, voltage-gated, type I, beta	0.012
Nr4a3	nuclear receptor subfamily 4, group A, member 3	0.012
Cxcr3	chemokine (C-X-C motif) receptor 3	0.012
Grm2	glutamate receptor, metabotropic 2	0.012
Mcam	melanoma cell adhesion molecule	0.012
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.012
Hlf	hepatic leukemia factor	0.012
Arl6ip5	ADP-ribosylation-like factor 6 interacting protein 5	0.011
Uhmk1	U2AF homology motif (UHM) kinase 1	0.011
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)	0.011
Klk6	kallikrein related-peptidase 6	0.011
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.011
Afap1	actin filament associated protein 1	0.011
Il18	interleukin 18	0.011
Npffr2	neuropeptide FF receptor 2	0.011	Rat
Ccl3	chemokine (C-C motif) ligand 3	0.011	Human
Apln	apelin	0.011
LOC100361486	rCG55595-like	0.011
Cyp21a1	cytochrome P450, family 21, subfamily a, polypeptide 1	0.011
Gnrhr	gonadotropin releasing hormone receptor	0.011
Kif12	kinesin family member 12	0.011
Mas1	MAS1 oncogene	0.011
Zic1	Zic family member 1 (odd-paired homolog, Drosophila)	0.011
Rho	rhodopsin	0.011
Mybpc2	myosin binding protein C, fast-type	0.011
Scnn1a	sodium channel, nonvoltage-gated 1 alpha	0.011
Fut9	fucosyltransferase 9 (alpha (1,3) fucosyltransferase)	0.011
Lrrc4b	leucine rich repeat containing 4B	0.011
Calcb	calcitonin-related polypeptide, beta	0.011
Grm5	glutamate receptor, metabotropic 5	0.011
Cd38	CD38 molecule	0.011
Slc14a2	solute carrier family 14 (urea transporter), member 2	0.011
Prkcg	protein kinase C, gamma	0.011
Clec4a3	C-type lectin domain family 4, member a3	0.011
Prl5a1	prolactin family 5, subfamily a, member 1	0.011
Slc2a3	solute carrier family 2 (facilitated glucose transporter), member 3	0.011
Tyrobp	Tyro protein tyrosine kinase binding protein	0.011
Atp12a	ATPase, H+/K+ transporting, nongastric, alpha polypeptide	0.011
LOC60591	calcium-activated potassium channel beta subunit	0.011
Syn3	synapsin III	0.011
Cntn5	contactin 5	0.011
Ncan	neurocan	0.011
Tchh	trichohyalin	0.011
Zp1	zona pellucida glycoprotein 1 (sperm receptor)	0.011
Kif6	kinesin family member 6	0.011
Prl2a1	Prolactin family 2, subfamily a, member 1	0.010
Fxyd7	FXYD domain-containing ion transport regulator 7	0.010
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.010
Atp6ap1	ATPase, H+ transporting, lysosomal accessory protein 1	0.010
Gna15	guanine nucleotide binding protein, alpha 15	0.010
Trh	thyrotropin releasing hormone	0.010
Cpne9	copine family member IX	0.010
Cryba1	crystallin, beta A1	0.010
Dbc1	deleted in bladder cancer 1 (human)	0.010
Cntn1	contactin 1	0.010
Havcr1	hepatitis A virus cellular receptor 1	0.010
Cd46	CD46 molecule, complement regulatory protein	0.010
Abi3	ABI family, member 3	0.010
Ryr2	ryanodine receptor 2, cardiac	0.010
Il10	interleukin 10	0.010
Hoxa2	homeo box A2	0.010
Kcng2	potassium voltage-gated channel, subfamily G, member 2	0.010
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.010
Ceacam9	carcinoembryonic antigen-related cell adhesion molecule 9	0.010
Trhr	thyrotropin releasing hormone receptor	0.010
Fgf8	fibroblast growth factor 8	0.010
Hcrtr2	hypocretin (orexin) receptor 2	0.010	Rat
Adamts15	ADAM metallopeptidase with thrombospondin type 1 motif, 15	0.010
Nell1	NEL-like 1 (chicken)	0.010