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Process View

Danio rerio

9 genes annotated in zebrafish

enteroendocrine cell differentiation

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "enteroendocrine cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "enteroendocrine cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
olig2	oligodendrocyte lineage transcription factor 2	0.925
isl1	islet1	0.869
lhx1a	LIM homeobox 1a	0.861	Zebrafish
nkx2.2a	NK2 transcription factor related 2a	0.777	Mouse
hlxb9la	homeo box HB9 like a	0.709	Zebrafish
pdx1	pancreatic and duodenal homeobox 1	0.609	Human
ins	preproinsulin	0.570
dla	deltaA	0.527
sst1.1	somatostatin 1, tandem duplicate 1	0.465
gcga	glucagon a and glucagon a-like	0.364
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.352
evx1	even-skipped homeobox 1	0.333
otpb	orthopedia homolog b	0.315
mnx1	motor neuron and pancreas homeobox 1	0.309
neurog1	neurogenin 1	0.288
pax6b	paired box gene 6b	0.255
lef1	lymphocyte enhancer binding factor 1	0.240
nkx6.1	NK6 transcription factor related, locus 1 (Drosophila)	0.221
dlb	deltaB	0.201
olfm2	olfactomedin 2	0.185
gdf6a	growth differentiation factor 6a	0.183
shha	sonic hedgehog a	0.167
lhx5	LIM homeobox 5	0.148	Zebrafish
dbx1a	developing brain homeobox 1a	0.124
pax8	paired box gene 8	0.122
mib	mind bomb	0.117
foxa1	forkhead box A1	0.107
prox1	prospero-related homeobox gene 1	0.104
ascl1b	achaete-scute complex-like 1b (Drosophila)	0.100
vsx2	visual system homeobox 2	0.093	Zebrafish
vsx1	visual system homeobox 1 homolog, chx10-like	0.084	Zebrafish
hoxb1a	homeo box B1a	0.083
otx2	orthodenticle homolog 2	0.083
dlx6a	distal-less homeobox gene 6a	0.082
pax6a	paired box gene 6a	0.078	Human Zebrafish Mouse Rat
foxa2	forkhead box A2	0.075
bmp2b	bone morphogenetic protein 2b	0.074
hhex	hematopoietically expressed homeobox	0.074
hlxb9lb	homeo box HB9 like b	0.072	Zebrafish
olig4	oligodendrocyte transcription factor 4	0.070
osr2	odd-skipped related 2 (Drosophila)	0.069
coe2	coe2	0.069
met	met proto-oncogene (hepatocyte growth factor receptor)	0.066
pax4	paired box 4	0.063
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.060
tal2	T-cell acute lymphocytic leukemia 2	0.060
adcyap1r1	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	0.058
tll1	tolloid-like 1	0.055
pax9	paired box gene 9	0.055
foxa3	forkhead box A3	0.055
nkx2.3	NK2 transcription factor related 3	0.052
tpbgl	trophoblast glycoprotein-like	0.049
dlx2b	distal-less homeobox gene 2b	0.049
irx3a	iroquois homeobox protein 3a	0.048
dld	deltaD	0.046
nkx6.2	NK6 transcription factor related, locus 2	0.044
neurod	neurogenic differentiation	0.042	Mouse
six3a	sine oculis homeobox homolog 3a	0.041
dlx1a	distal-less homeobox gene 1a	0.041
eomesa	eomesodermin homolog a	0.039
inab	internexin neuronal intermediate filament protein, alpha b	0.038
barhl2	BarH-like 2	0.037
th	tyrosine hydroxylase	0.036
atoh7	atonal homolog 7	0.035
dlx2a	distal-less homeobox gene 2a	0.035
her5	hairy-related 5	0.034
foxp2	forkhead box P2	0.033
ndr2	nodal-related 2	0.031
rx3	retinal homeobox gene 3	0.030
pou3f3b	POU class 3 homeobox 3b	0.030
lhx3	LIM homeobox 3	0.028
cry2b	cryptochrome 2b	0.028
fgf20a	fibroblast growth factor 20a	0.027
jag1b	jagged 1b	0.026
phox2a	paired-like homeobox 2a	0.025
pou3f2	POU class 3 homeobox 2	0.025
meis2.2	myeloid ecotropic viral integration site 2.2	0.024
bmp4	bone morphogenetic protein 4	0.024	Human
flot1	flotillin 1	0.024
eng2b	engrailed 2b	0.023
arntl1b	aryl hydrocarbon receptor nuclear translocator-like 1b	0.023	Mouse
camkvb	CaM kinase-like vesicle-associated b	0.022
insm1a	insulinoma-associated 1a	0.022
hnf4a	hepatocyte nuclear factor 4, alpha	0.022
zgc:112180	zgc:112180	0.021
fzd5	frizzled homolog 5	0.021
plxnb2a	plexin b2a	0.021
nkx2.1b	NK2 homeobox 1b	0.021
dcc	deleted in colorectal carcinoma	0.021
sox9b	SRY-box containing gene 9b	0.020
osr1	odd-skipped related 1 (Drosophila)	0.019
sst2	somatostatin 2	0.019
nfasca	neurofascin homolog (chicken) a	0.019
nxph1	neurexophilin 1	0.019
sult3st1	sulfotransferase family 3, cytosolic sulfotransferase 1	0.019
ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.018
ebf3	early B-cell factor 3	0.018
ihha	Indian hedgehog homolog a	0.018
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.017
ek1	eph-like kinase 1	0.017
dscam	Down syndrome cell adhesion molecule	0.017
acvr1b	activin A receptor, type IB	0.017
hmx4	H6 family homeobox 4	0.017
prl	prolactin	0.016
notch1a	notch homolog 1a	0.016
six2a	sine oculis-related homeobox 2a	0.016
chrna2a	cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)	0.016
wnt8b	wingless-type MMTV integration site family, member 8b	0.016
zic1	zic family member 1 (odd-paired homolog, Drosophila)	0.016
flh	floating head	0.015
pax2a	paired box gene 2a	0.015
jag2	jagged 2	0.015
nr5a2	nuclear receptor subfamily 5, group A, member 2	0.015
fech	ferrochelatase	0.015
gbx1	gastrulation brain homeobox 1	0.015	Zebrafish
mecom	MDS1 and EVI1 complex locus	0.015
eve1	even-skipped-like1	0.015
tbr1b	T-box, brain, 1b	0.015
clock3	clock homolog 3 (mouse)	0.015	Mouse
sp7	Sp7 transcription factor	0.015
neurod4	neurogenic differentiation 4	0.015
lhx2b	LIM homeobox 2b	0.014	Zebrafish
gfap	glial fibrillary acidic protein	0.014
mecp2	methyl CpG binding protein 2	0.014
tbx2b	T-box 2b	0.014
ghrl	ghrelin/obestatin preprohormone	0.014
itgav	integrin, alpha V	0.014
itgb3b	integrin beta 3b	0.014
wu:fi18a01	wu:fi18a01	0.013
apaf1	apoptotic protease activating factor 1	0.013
gbx2	gastrulation brain homeo box 2	0.013	Zebrafish
p2rx8	purinergic receptor P2X, ligand-gated ion channel, 8	0.013
ap1m2	adaptor-related protein complex 1, mu 2 subunit	0.013
ptch2	patched 2	0.013
meis3	myeloid ecotropic viral integration site 3	0.013
runx2a	runt-related transcription factor 2a	0.013
dlx4b	distal-less homeobox gene 4b	0.013
ism1	isthmin 1	0.012
cp	ceruloplasmin	0.012
gata4	GATA-binding protein 4	0.012
eng2a	engrailed 2a	0.012
nr2e3	nuclear receptor subfamily 2, group E, member 3	0.012
slc17a6a	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6a	0.012
stmn4	stathmin-like 4	0.012
zic6	zic family member 6	0.012
elavl3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.012
wnt1	wingless-type MMTV integration site family, member 1	0.012
tlx2	T-cell leukemia, homeobox 2	0.012
olig3	oligodendrocyte transcription factor 3	0.011
oprd1b	opioid receptor, delta 1b	0.011
tysnd1	trypsin domain containing 1	0.011
shmt2	serine hydroxymethyltransferase 2 (mitochondrial)	0.011
cdx4	caudal type homeo box transcription factor 4	0.011
sox17	SRY-box containing gene 17	0.011
sec13	SEC13 homolog (S. cerevisiae)	0.011
ythdf1	YTH domain family, member 1	0.011
irx4b	iroquois homeobox protein 4b	0.010
tgfb2	transforming growth factor, beta 2	0.010
ihhb	Indian hedgehog homolog b	0.010
hoxa4a	homeo box A4a	0.010
st8sia7.1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 7.1	0.010