IMP
Process View
optic cup morphogenesis involved in camera type eye development
The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "optic cup morphogenesis involved in camera type eye development"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| isl1 | islet1 | 0.657 | Zebrafish | |
| lmx1b.1 | LIM homeobox transcription factor 1, beta 1 | 0.652 | ||
| fgf3 | fibroblast growth factor 3 | 0.611 | ||
| lhx2b | LIM homeobox 2b | 0.505 | Zebrafish | |
| lmx1b.2 | LIM homeobox transcription factor 1, beta 2 | 0.483 | ||
| dla | deltaA | 0.387 | ||
| rx3 | retinal homeobox gene 3 | 0.376 | ||
| pitx2 | paired-like homeodomain transcription factor 2 | 0.326 | ||
| sox10 | SRY-box containing gene 10 | 0.310 | ||
| gata3 | GATA-binding protein 3 | 0.260 | ||
| lhx5 | LIM homeobox 5 | 0.252 | Zebrafish | |
| pax6b | paired box gene 6b | 0.245 | ||
| chd | chordin | 0.234 | ||
| prdm1a | PR domain containing 1a, with ZNF domain | 0.231 | ||
| nkx2.2a | NK2 transcription factor related 2a | 0.218 | ||
| barhl2 | BarH-like 2 | 0.201 | ||
| ascl1a | achaete-scute complex-like 1a (Drosophila) | 0.200 | ||
| foxi1 | forkhead box I1 | 0.191 | ||
| otx2 | orthodenticle homolog 2 | 0.188 | ||
| dlx2b | distal-less homeobox gene 2b | 0.182 | ||
| gbx2 | gastrulation brain homeo box 2 | 0.180 | ||
| dmbx1a | diencephalon/mesencephalon homeobox 1a | 0.176 | ||
| nkx2.1a | NK2 homeobox 1a | 0.163 | ||
| pax8 | paired box gene 8 | 0.161 | ||
| pax6a | paired box gene 6a | 0.157 | ||
| six3a | sine oculis homeobox homolog 3a | 0.139 | ||
| vax2 | ventral anterior homeobox 2 | 0.129 | ||
| neurog1 | neurogenin 1 | 0.116 | ||
| sim1a | single-minded homolog 1a (Drosophila) | 0.116 | ||
| tfap2c | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.114 | ||
| dlx2a | distal-less homeobox gene 2a | 0.109 | ||
| lhx3 | LIM homeobox 3 | 0.109 | ||
| olig2 | oligodendrocyte lineage transcription factor 2 | 0.108 | ||
| dlx1a | distal-less homeobox gene 1a | 0.105 | ||
| atoh7 | atonal homolog 7 | 0.101 | ||
| six3b | sine oculis homeobox homolog 3b | 0.096 | ||
| shha | sonic hedgehog a | 0.089 | ||
| six4b | sine oculis homeobox homolog 4b | 0.088 | ||
| nr2e1 | nuclear receptor subfamily 2, group E, member 1 | 0.084 | ||
| eya1 | eyes absent homolog 1 | 0.082 | ||
| dbx1a | developing brain homeobox 1a | 0.081 | ||
| lhx6 | LIM homeobox 6 | 0.076 | Zebrafish | |
| mab21l2 | mab-21-like 2 | 0.070 | ||
| dlx6a | distal-less homeobox gene 6a | 0.063 | ||
| gata2a | GATA-binding protein 2a | 0.062 | ||
| zic1 | zic family member 1 (odd-paired homolog, Drosophila) | 0.060 | ||
| dld | deltaD | 0.058 | ||
| dlx3b | distal-less homeobox gene 3b | 0.056 | ||
| foxg1a | forkhead box G1a | 0.056 | ||
| notch1a | notch homolog 1a | 0.052 | ||
| dlx4a | distal-less homeobox gene 4a | 0.049 | ||
| foxd3 | forkhead box D3 | 0.046 | ||
| lhx1b | LIM homeobox 1b | 0.045 | Zebrafish | |
| coe2 | coe2 | 0.044 | ||
| mib | mind bomb | 0.044 | ||
| hand2 | heart and neural crest derivatives expressed transcript 2 | 0.040 | ||
| vax1 | ventral anterior homeobox 1 | 0.040 | ||
| fezf2 | FEZ family zinc finger 2 | 0.039 | ||
| boc | brother of CDO | 0.037 | ||
| dlx4b | distal-less homeobox gene 4b | 0.037 | ||
| irx1b | iroquois homeobox protein 1, b | 0.037 | ||
| osr1 | odd-skipped related 1 (Drosophila) | 0.036 | ||
| grem2 | gremlin 2, cysteine knot superfamily | 0.034 | ||
| zic6 | zic family member 6 | 0.034 | ||
| tll1 | tolloid-like 1 | 0.034 | ||
| tlx2 | T-cell leukemia, homeobox 2 | 0.033 | ||
| foxp2 | forkhead box P2 | 0.032 | ||
| shhb | sonic hedgehog b | 0.032 | ||
| ndr2 | nodal-related 2 | 0.031 | ||
| osr2 | odd-skipped related 2 (Drosophila) | 0.030 | ||
| nkx2.3 | NK2 transcription factor related 3 | 0.029 | ||
| tbx2b | T-box 2b | 0.029 | ||
| eng2b | engrailed 2b | 0.029 | ||
| otpb | orthopedia homolog b | 0.028 | ||
| znf503 | zinc finger protein 503 | 0.027 | ||
| foxj1b | forkhead box J1b | 0.027 | ||
| irx7 | iroquois homeobox protein 7 | 0.027 | ||
| fgfr4 | fibroblast growth factor receptor 4 | 0.026 | ||
| six4a | sine oculis homeobox homolog 4a | 0.026 | ||
| hhip | hedgehog interacting protein | 0.025 | ||
| tfap2a | transcription factor AP-2 alpha | 0.025 | Mouse | |
| nkx1.2la | NK1 transcription factor related 2-like,a | 0.025 | ||
| nkx2.1b | NK2 homeobox 1b | 0.024 | ||
| tp63 | tumor protein p63 | 0.024 | ||
| meis2.1 | myeloid ecotropic viral integration site 2.1 | 0.024 | ||
| pcdh10b | protocadherin 10b | 0.024 | ||
| elavl3 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 0.023 | ||
| tshb | thyroid stimulating hormone, beta subunit | 0.023 | ||
| slc6a6 | solute carrier family 6 (neurotransmitter transporter, taurine), member 6 | 0.023 | ||
| arx | aristaless related homeobox | 0.022 | ||
| otpa | orthopedia homolog a | 0.021 | ||
| dlb | deltaB | 0.020 | ||
| robo2 | roundabout homolog 2 | 0.019 | ||
| emx3 | empty spiracles homeobox 3 | 0.019 | ||
| sox1a | SRY-box containing gene 1a | 0.018 | ||
| otx1a | orthodenticle homolog 1a | 0.018 | ||
| fsta | follistatin a | 0.018 | ||
| chrna6 | cholinergic receptor, nicotinic, alpha 6 | 0.018 | ||
| tac1 | tachykinin 1 | 0.017 | ||
| lhx1a | LIM homeobox 1a | 0.017 | Zebrafish | |
| cadm3 | cell adhesion molecule 3 | 0.017 | ||
| fgf8a | fibroblast growth factor 8 a | 0.016 | ||
| barx1 | BarH-like homeobox 1 | 0.016 | ||
| unc5b | unc-5 homolog B (C. elegans) | 0.016 | ||
| jag1b | jagged 1b | 0.015 | ||
| chrna2a | cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal) | 0.015 | ||
| foxe3 | forkhead box E3 | 0.015 | ||
| inab | internexin neuronal intermediate filament protein, alpha b | 0.015 | ||
| six2a | sine oculis-related homeobox 2a | 0.015 | ||
| mecom | MDS1 and EVI1 complex locus | 0.015 | ||
| otx1b | orthodenticle homolog 1b | 0.015 | ||
| fgf8b | fibroblast growth factor 8 b | 0.015 | ||
| adcyap1r1 | adenylate cyclase activating polypeptide 1 (pituitary) receptor type I | 0.015 | ||
| sox19a | SRY-box containing gene 19a | 0.015 | ||
| eng2a | engrailed 2a | 0.014 | ||
| insm1b | insulinoma-associated 1b | 0.014 | ||
| jag2 | jagged 2 | 0.014 | ||
| gdf6b | growth differentiation factor 6b | 0.014 | ||
| oprk1 | opioid receptor, kappa 1 | 0.013 | ||
| hmx4 | H6 family homeobox 4 | 0.013 | ||
| foxc1b | forkhead box C1b | 0.013 | ||
| isl2a | islet2a | 0.013 | Zebrafish | |
| th | tyrosine hydroxylase | 0.013 | ||
| neurod4 | neurogenic differentiation 4 | 0.013 | ||
| wnt1 | wingless-type MMTV integration site family, member 1 | 0.012 | ||
| bmp4 | bone morphogenetic protein 4 | 0.012 | ||
| si:dkey-24g18.2 | si:dkey-24g18.2 | 0.012 | ||
| foxn4 | forkhead box N4 | 0.012 | ||
| hey1 | hairy/enhancer-of-split related with YRPW motif 1 | 0.012 | ||
| pcdh18a | protocadherin 18a | 0.012 | ||
| ntn1a | netrin 1a | 0.011 | ||
| pax9 | paired box gene 9 | 0.011 | ||
| dlc | deltaC | 0.011 | ||
| foxa1 | forkhead box A1 | 0.011 | ||
| nkx2.2b | NK2 transcription factor related 2b | 0.011 | ||
| runx3 | runt-related transcription factor 3 | 0.010 | ||
| efna5a | ephrin A5a | 0.010 | ||
| meis3 | myeloid ecotropic viral integration site 3 | 0.010 | ||
| foxb1.1 | forkhead box B1.1 | 0.010 | ||
| twist3 | twist3 | 0.010 | ||
| fgf19 | fibroblast growth factor 19 | 0.010 | ||
| evx1 | even-skipped homeobox 1 | 0.010 | ||
| bhlhe22 | basic helix-loop-helix family, member e22 | 0.010 |