The network for 'negative regulation of cell cycle phase transition' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of cell cycle phase transition

Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle phase transition.

Drosophila melanogaster
Name Description Probability Func Analog Organism
p53 CG33336 gene product from transcript CG33336-RB 0.995
lok loki 0.992
Ras85D Ras oncogene at 85D 0.987
Pp1-87B Protein phosphatase 1 at 87B 0.973
tefu telomere fusion 0.964
Akt1 CG4006 gene product from transcript CG4006-RA 0.963
Brca2 Breast cancer 2, early onset homolog 0.958
MED6 Mediator complex subunit 6 0.955
skpA CG16983 gene product from transcript CG16983-RD 0.943
CSN5 COP9 complex homolog subunit 5 0.939
CycD Cyclin D 0.921
Cdc37 CG12019 gene product from transcript CG12019-RA 0.887
Iswi Imitation SWI 0.877
hay haywire 0.862
mei-9 meiotic 9 0.850
BRWD3 CG31132 gene product from transcript CG31132-RA 0.816
cnn centrosomin 0.815
DNApol-eta CG7143 gene product from transcript CG7143-RA 0.806
mus304 mutagen-sensitive 304 0.791
MED17 Mediator complex subunit 17 0.784
Kap-alpha3 karyopherin alpha3 0.758
fzy fizzy 0.748
gro groucho 0.733
mus205 mutagen-sensitive 205 0.731
Caf1 Chromatin assembly factor 1 subunit 0.711
cdc2 CG5363 gene product from transcript CG5363-RA 0.693
CSN3 COP9 complex homolog subunit 3 0.686
Dref DNA replication-related element factor 0.627
CG8159 CG8159 gene product from transcript CG8159-RB 0.623
phl pole hole 0.604
imd immune deficiency 0.597
sax saxophone 0.584
Su(z)12 CG8013 gene product from transcript CG8013-RA 0.583
His2Av Histone H2A variant 0.580
Hdac3 Histone deacetylase 3 0.568
rux roughex 0.564
CycB3 Cyclin B3 0.546
eff effete 0.524
scra scraps 0.523
Cp190 Centrosomal protein 190kD 0.521
Rpd3 CG7471 gene product from transcript CG7471-RA 0.520
Hcf Host cell factor 0.509
Smox Smad on X 0.507
CkIIbeta Casein kinase II beta subunit 0.492
MAGE CG10059 gene product from transcript CG10059-RA 0.478
ttv tout-velu 0.477
plu plutonium 0.472
Art1 Arginine methyltransferase 1 0.468
Bap55 Brahma associated protein 55kD 0.466
Crag Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein 0.465
mus308 mutagen-sensitive 308 0.465
morgue modifier of rpr and grim, ubiquitously expressed 0.460
Pp2A-29B Protein phosphatase 2A at 29B 0.457
alphaTub67C alpha-Tubulin at 67C 0.454
swm second mitotic wave missing 0.454
Ercc1 CG10215 gene product from transcript CG10215-RA 0.450
CG9915 CG9915 gene product from transcript CG9915-RB 0.442
Cdk4 Cyclin-dependent kinase 4 0.441
mus309 mutagen-sensitive 309 0.435
RanGap Ran GTPase activating protein 0.430
rad50 CG6339 gene product from transcript CG6339-RD 0.430
Cul-2 Cullin-2 0.429
CycE Cyclin E 0.425
CSN4 COP9 complex homolog subunit 4 0.422
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.407
rl rolled 0.403
CDC45L CG3658 gene product from transcript CG3658-RA 0.398
cdm cadmus 0.395
esc extra sexcombs 0.393
spn-B spindle B 0.390
Top2 Topoisomerase 2 0.377
cdc2c CG10498 gene product from transcript CG10498-RC 0.373
nbs CG6754 gene product from transcript CG6754-RC 0.369
CG5524 CG5524 gene product from transcript CG5524-RA 0.364
ago archipelago 0.359
Mcm3 Minichromosome maintenance 3 0.350
RecQ5 homolog of RecQ 0.347
Nup50 Nucleoporin 50 0.341
AGO2 Argonaute 2 0.335
RecQ4 CG7487 gene product from transcript CG7487-RA 0.331
brm brahma 0.329
mei-41 meiotic 41 0.323
Rcd1 Reduction in Cnn dots 1 0.318
Myd88 CG2078 gene product from transcript CG2078-RA 0.308
key kenny 0.303
flfl falafel 0.297
dre4 CG1828 gene product from transcript CG1828-RB 0.296
asp abnormal spindle 0.296
MED31 Mediator complex subunit 31 0.295
Mad Mothers against dpp 0.293
wee CG4488 gene product from transcript CG4488-RA 0.291
yki yorkie 0.285
caz cabeza 0.285
Cul-3 Cullin-3 0.285
tld tolloid 0.282
SNF1A SNF1A/AMP-activated protein kinase 0.281
Rel Relish 0.280
Snr1 Snf5-related 1 0.277
CSN7 COP9 complex homolog subunit 7 0.272
CG9772 CG9772 gene product from transcript CG9772-RB 0.266
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
rnr-1 Protein RNR-1 0.049
swsn-7 Protein SWSN-7 0.030
knl-1 Protein KNL-1 0.022
npp-16 Protein NPP-16 0.017
csn-3 Protein CSN-3 0.016
D1081.8 Protein D1081.8 0.016
dsh-2 Protein DSH-2 0.015
his-6 Protein HIS-6 0.014
his-42 Protein HIS-42 0.014
his-45 Protein HIS-45 0.013
csn-5 Protein CSN-5 0.013
hcf-1 Protein HCF-1 0.012
set-1 Protein SET-1 0.012
brc-1 Protein BRC-1 0.011
lin-9 Protein LIN-9 0.011
CELE_C24H12.5 Protein C24H12.5 0.011
plk-1 Protein PLK-1 0.010
asd-1 Protein ASD-1 0.010
hpo-9 Protein HPO-9 0.010
gpr-1 Protein GPR-1 0.010
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Danio rerio
Name Description Probability Func Analog Organism
ccnb1 cyclin B1 0.926
plk1 polo-like kinase 1 (Drosophila) 0.284
rasl11b RAS-like, family 11, member B 0.195
kif23 kinesin family member 23 0.161
erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog 0.149
ccna2 cyclin A2 0.149
ccnb2 cyclin B2 0.147
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.140
zff9 zinc finger protein 9 0.135
stil TAL1 (SCL) interrupting locus 0.131
caprin1a cell cycle associated protein 1a 0.122
sae1 SUMO1 activating enzyme subunit 1 0.096
msh6 mutS homolog 6 (E. coli) 0.080
ncapg non-SMC condensin I complex, subunit G 0.080
cand1 cullin-associated and neddylation-dissociated 1 0.075
ccnd1 cyclin D1 0.061
cdk8 cyclin-dependent kinase 8 0.060
snrpc small nuclear ribonucleoprotein polypeptide C 0.060
erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b 0.056
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.056
smc4 structural maintenance of chromosomes 4 0.051
ccne cyclin E 0.050
aurka aurora kinase A 0.050
mapk3 mitogen-activated protein kinase 3 0.047
tgif1 TGFB-induced factor homeobox 1 0.046
ube2g2 ubiquitin-conjugating enzyme E2G 2 0.045
rap1a RAP1A, member of RAS oncogene family 0.045
si:ch211-59d15.5 si:ch211-59d15.5 0.045
tp53 tumor protein p53 0.043
rtkn2 rhotekin 2 0.041
rpa3 replication protein A3 0.039
si:ch211-69g19.2 si:ch211-69g19.2 0.039
sass6 spindle assembly 6 homolog (C. elegans) 0.039
tbc1d23 TBC1 domain family, member 23 0.039
aurkb aurora kinase B 0.035
cstf1 cleavage stimulation factor, 3' pre-RNA, subunit 1 0.034
pold1 polymerase (DNA directed), delta 1, catalytic subunit 0.034
rbb4 retinoblastoma binding protein 4 0.034
oep one-eyed pinhead 0.033
rqcd1 RCD1 required for cell differentiation1 homolog (S. pombe) 0.033
si:ch211-244o22.2 si:ch211-244o22.2 0.032
rhoab ras homolog gene family, member Ab 0.031
dlgap5 discs, large (Drosophila) homolog-associated protein 5 0.030
kif14 kinesin family member 14 0.029
ube2i ubiquitin-conjugating enzyme E2I 0.029
g2e3 G2/M-phase specific E3 ubiquitin ligase 0.029
dusp1 dual specificity phosphatase 1 0.029
tfam transcription factor A, mitochondrial 0.028
szl sizzled 0.028
skp2 S-phase kinase-associated protein 2 (p45) 0.027
cul3a cullin 3a 0.027
spock3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 0.026
crestin crestin 0.026
chaf1b chromatin assembly factor 1, subunit B 0.026
polr2b polymerase (RNA) II (DNA directed) polypeptide B 0.026
cav1 caveolin 1 0.026
rbpms2 RNA binding protein with multiple splicing 2 0.026
ncbp2 nuclear cap binding protein subunit 2 0.025
pafah1b1a platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a 0.024
prkrir protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) 0.024
zgc:153910 zgc:153910 0.024
bnip3lb BCL2/adenovirus E1B interacting protein 3-like b 0.023
usp4 ubiquitin specific protease 4 (proto-oncogene) 0.023
ppp2r5eb protein phosphatase 2, regulatory subunit B', epsilon isoform b 0.023
mitfa microphthalmia-associated transcription factor a 0.023
cstf3 cleavage stimulation factor, 3' pre-RNA, subunit 3 0.022
cnot8 CCR4-NOT transcription complex, subunit 8 0.022
top2a topoisomerase (DNA) II alpha 0.021
cpsf1 cleavage and polyadenylation specific factor 1 0.021
glmna glomulin, FKBP associated protein a 0.021
ybx1 Y box binding protein 1 0.021
ung uracil-DNA glycosylase 0.020
c20orf14 c20orf14 homolog (H. sapiens) 0.020
irf6 interferon regulatory factor 6 0.020
fabp7a fatty acid binding protein 7, brain, a 0.020
orc1 origin recognition complex, subunit 1 0.020
rbbp6 retinoblastoma binding protein 6 0.020
id2a inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a 0.019
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.019
arl4ab ADP-ribosylation factor-like 4ab 0.019
smad2 MAD homolog 2 (Drosophila) 0.018
btg2 B-cell translocation gene 2 0.018
ck2b casein kinase 2 beta 0.018
kpna3 karyopherin (importin) alpha 3 0.018
erbb3a v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a 0.018
lsm8 LSM8 homolog, U6 small nuclear RNA associated 0.018
cdt1 chromatin licensing and DNA replication factor 1 0.018
tgfbr2 transforming growth factor, beta receptor II 0.018
marcksl1 MARCKS-like 1 0.018
cd99l2 CD99 antigen-like 2 0.018
smc1al structural maintenance of chromosomes 1A, like 0.018
gdf6a growth differentiation factor 6a 0.017
smc3 structural maintenance of chromosomes 3 0.017
ptp4a3 protein tyrosine phosphatase type IVA, member 3 0.017
crkl v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.017
LOC100536090 targeting protein for Xklp2-B-like 0.017
ywhabb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b 0.016
atrx alpha thalassemia/mental retardation syndrome X-linked homolog (human) 0.016
kif11 kinesin family member 11 0.016
tfip11 tuftelin interacting protein 11 0.016
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Homo sapiens
Name Description Probability Func Analog Organism
TP53 tumor protein p53 1.000
CDK2 cyclin-dependent kinase 2 1.000
RB1 retinoblastoma 1 0.999
COPS5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) 0.986
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.984
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.971
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.960
CHEK1 CHK1 checkpoint homolog (S. pombe) 0.953
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.912
CCNA2 cyclin A2 0.906
CHEK2 CHK2 checkpoint homolog (S. pombe) 0.901
CDK8 cyclin-dependent kinase 8 0.901
PLK1 polo-like kinase 1 0.896
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.872
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.849
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.832
MED1 mediator complex subunit 1 0.819
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.817
XIAP X-linked inhibitor of apoptosis 0.809
RAD51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.795
RAD50 RAD50 homolog (S. cerevisiae) 0.751
BCL2 B-cell CLL/lymphoma 2 0.749
BCL2L1 BCL2-like 1 0.747
COPS4 COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) 0.744
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.734
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.731
PCNA proliferating cell nuclear antigen 0.723
BTRC beta-transducin repeat containing 0.721
BUB1B budding uninhibited by benzimidazoles 1 homolog beta (yeast) 0.721
BRCA1 breast cancer 1, early onset 0.706
CDC7 cell division cycle 7 homolog (S. cerevisiae) 0.704
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.684
NBN nibrin 0.681
MCM2 minichromosome maintenance complex component 2 0.681
CUL2 cullin 2 0.678
CCND3 cyclin D3 0.675
CLSPN claspin 0.664
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.659
PKM2 pyruvate kinase, muscle 0.646
MCM7 minichromosome maintenance complex component 7 0.644
SKP2 S-phase kinase-associated protein 2 (p45) 0.623
TOP1 topoisomerase (DNA) I 0.615
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.589
MCM10 minichromosome maintenance complex component 10 0.579
CCT8 chaperonin containing TCP1, subunit 8 (theta) 0.577
TOPBP1 topoisomerase (DNA) II binding protein 1 0.545
CSNK2B casein kinase 2, beta polypeptide 0.524
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 0.518
MED28 mediator complex subunit 28 0.479
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.477
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.458
CUL1 cullin 1 0.454
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.454
CCNB1 cyclin B1 0.446
CDK4 cyclin-dependent kinase 4 0.440
RBBP8 retinoblastoma binding protein 8 0.435
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.433
HDAC1 histone deacetylase 1 0.430
CDC25A cell division cycle 25 homolog A (S. pombe) 0.427
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.412
COPS8 COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) 0.406
ZWINT ZW10 interactor 0.405
ATM ataxia telangiectasia mutated 0.391
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.381
MSH6 mutS homolog 6 (E. coli) 0.375
RBL1 retinoblastoma-like 1 (p107) 0.370
CDC6 cell division cycle 6 homolog (S. cerevisiae) 0.361
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.360
COPS3 COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis) 0.356
JUN jun proto-oncogene 0.354
MED29 mediator complex subunit 29 0.349
RBL2 retinoblastoma-like 2 (p130) 0.347
RAD1 RAD1 homolog (S. pombe) 0.338
E2F1 E2F transcription factor 1 0.338
SLX1B SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) 0.336
GFER growth factor, augmenter of liver regeneration 0.334
CNOT6 CCR4-NOT transcription complex, subunit 6 0.334
SIRT1 sirtuin 1 0.333
IER3 immediate early response 3 0.333
CCND1 cyclin D1 0.329
COPS6 COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) 0.325
MDC1 mediator of DNA-damage checkpoint 1 0.325
OTUB1 OTU domain, ubiquitin aldehyde binding 1 0.320
MED10 mediator complex subunit 10 0.317
UBA1 ubiquitin-like modifier activating enzyme 1 0.315
FBXW11 F-box and WD repeat domain containing 11 0.311
FAS Fas (TNF receptor superfamily, member 6) 0.306
BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast) 0.306
GPS1 G protein pathway suppressor 1 0.294
NCOA1 nuclear receptor coactivator 1 0.293
MED4 mediator complex subunit 4 0.273
CDC5L CDC5 cell division cycle 5-like (S. pombe) 0.272
PARP1 poly (ADP-ribose) polymerase 1 0.270
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.268
TOP2A topoisomerase (DNA) II alpha 170kDa 0.261
BAX BCL2-associated X protein 0.256
CDC20 cell division cycle 20 homolog (S. cerevisiae) 0.249
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.247
TRIP13 thyroid hormone receptor interactor 13 0.247
POLE3 polymerase (DNA directed), epsilon 3 (p17 subunit) 0.244
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Trp53 transformation related protein 53 1.000
Rb1 retinoblastoma 1 0.999
Brca1 breast cancer 1 0.999
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.984
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.969
Brca2 breast cancer 2 0.965
E2f1 E2F transcription factor 1 0.934
Dtl denticleless homolog (Drosophila) 0.924
Nbn nibrin 0.884
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.866
Pten phosphatase and tensin homolog 0.804
Smad4 MAD homolog 4 (Drosophila) 0.800
Apc adenomatosis polyposis coli 0.790
Nf1 neurofibromatosis 1 0.749
Gtse1 G two S phase expressed protein 1 0.726
Mis18bp1 MIS18 binding protein 1 0.723
Mcm3 minichromosome maintenance deficient 3 (S. cerevisiae) 0.681
Arid1b AT rich interactive domain 1B (SWI-like) 0.677
Cdk4 cyclin-dependent kinase 4 0.640
Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.634
Msh2 mutS homolog 2 (E. coli) 0.633
Rpgrip1l Rpgrip1-like 0.624
Suz12 suppressor of zeste 12 homolog (Drosophila) 0.609
Ccnf cyclin F 0.598
Kif2c kinesin family member 2C 0.597
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.588
Kif11 kinesin family member 11 0.566
Trip13 thyroid hormone receptor interactor 13 0.541
Gps1 G protein pathway suppressor 1 0.510
Kif4 kinesin family member 4 0.501
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.464
Mybl2 myeloblastosis oncogene-like 2 0.462
Wdhd1 WD repeat and HMG-box DNA binding protein 1 0.434
Cenpk centromere protein K 0.421
Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.416
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.399
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.396
Mdm4 transformed mouse 3T3 cell double minute 4 0.385
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.379
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.373
Braf Braf transforming gene 0.366
Hells helicase, lymphoid specific 0.363
Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 0.361
Ccna2 cyclin A2 0.360
Orc1 origin recognition complex, subunit 1 0.358
Cdkn2c cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.358
Rad51ap1 RAD51 associated protein 1 0.353
Cdk2 cyclin-dependent kinase 2 0.351
Exo1 exonuclease 1 0.343
Atm ataxia telangiectasia mutated homolog (human) 0.341
Aspm asp (abnormal spindle)-like, microcephaly associated (Drosophila) 0.338
Sufu suppressor of fused homolog (Drosophila) 0.332
Prim1 DNA primase, p49 subunit 0.325
Kif23 kinesin family member 23 0.324
Kit kit oncogene 0.315
Dicer1 Dicer1, Dcr-1 homolog (Drosophila) 0.311
Shh sonic hedgehog 0.307
Rbl1 retinoblastoma-like 1 (p107) 0.301
Cdc25c cell division cycle 25 homolog C (S. pombe) 0.296
Dlgap5 discs, large (Drosophila) homolog-associated protein 5 0.295
Ttk Ttk protein kinase 0.294
Cdkn2a cyclin-dependent kinase inhibitor 2A 0.292
Ezh2 enhancer of zeste homolog 2 (Drosophila) 0.291
Rnf2 ring finger protein 2 0.285
Cenpf centromere protein F 0.280
Dna2 DNA replication helicase 2 homolog (yeast) 0.267
Ccdc99 coiled-coil domain containing 99 0.255
Plk1 polo-like kinase 1 (Drosophila) 0.255
E2f8 E2F transcription factor 8 0.251
Cul4a cullin 4A 0.251
Cdc6 cell division cycle 6 homolog (S. cerevisiae) 0.249
Prc1 protein regulator of cytokinesis 1 0.247
Hmmr hyaluronan mediated motility receptor (RHAMM) 0.246
Aurkb aurora kinase B 0.246
Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.230
Lin9 lin-9 homolog (C. elegans) 0.229
Blm Bloom syndrome, RecQ helicase-like 0.227
Cdk1 cyclin-dependent kinase 1 0.221
Ccne1 cyclin E1 0.220
Tcf19 transcription factor 19 0.217
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.217
Skil SKI-like 0.215
Sgol1 shugoshin-like 1 (S. pombe) 0.215
Rbl2 retinoblastoma-like 2 0.214
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.211
Timeless timeless homolog (Drosophila) 0.210
Chek1 checkpoint kinase 1 homolog (S. pombe) 0.210
Arid1a AT rich interactive domain 1A (SWI-like) 0.208
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.208
Cd80 CD80 antigen 0.206
Cdca5 cell division cycle associated 5 0.205
Ptch1 patched homolog 1 0.200
Ckap2 cytoskeleton associated protein 2 0.197
Top2a topoisomerase (DNA) II alpha 0.194
Trp63 transformation related protein 63 0.190
Ndel1 nuclear distribution gene E-like homolog 1 (A. nidulans) 0.190
Aurka aurora kinase A 0.187
Rfc3 replication factor C (activator 1) 3 0.178
Cdca7 cell division cycle associated 7 0.178
Cbl Casitas B-lineage lymphoma 0.172
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Top2a topoisomerase (DNA) II alpha 0.185
Pkm2 pyruvate kinase, muscle 0.098
Ccnb1 cyclin B1 0.077
Rrm2 ribonucleotide reductase M2 0.071
Kif2c kinesin family member 2C 0.066
Tnks2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.064
Zfand5 zinc finger, AN1-type domain 5 0.061
Spc25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) 0.057
Top2b topoisomerase (DNA) II beta 0.052
Cdca8 cell division cycle associated 8 0.048
Dlgap5 discs, large (Drosophila) homolog-associated protein 5 0.047
Cdkn3 cyclin-dependent kinase inhibitor 3 0.047
Traf4af1 TRAF4 associated factor 1 0.046
Ptbp1 polypyrimidine tract binding protein 1 0.046
Kifc1 kinesin family member C1 0.046
Racgap1 Rac GTPase-activating protein 1 0.044
Eif4h eukaryotic translation initiation factor 4H 0.043
Cdk4 cyclin-dependent kinase 4 0.043
LOC100364212 heterogeneous nuclear ribonucleoprotein K-like 0.042
Mcm3 minichromosome maintenance complex component 3 0.039
Aurkb aurora kinase B 0.037
Ccnb2 cyclin B2 0.037
Rgs19 regulator of G-protein signaling 19 0.037
Rbbp7 retinoblastoma binding protein 7 0.037
Pttg1 pituitary tumor-transforming 1 0.036
Cdk2 cyclin dependent kinase 2 0.036
Kif22 kinesin family member 22 0.035
Ube2c ubiquitin-conjugating enzyme E2C 0.035
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.035
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.035
Cops2 COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) 0.034
Taok1 TAO kinase 1 0.034
Rps6ka1 ribosomal protein S6 kinase polypeptide 1 0.033
Ppp1cb protein phosphatase 1, catalytic subunit, beta isoform 0.033
Usp9x ubiquitin specific peptidase 9, X-linked 0.032
Bnip3l BCL2/adenovirus E1B interacting protein 3-like 0.032
Hmmr hyaluronan mediated motility receptor (RHAMM) 0.032
Ppp1ca protein phosphatase 1, catalytic subunit, alpha isoform 0.031
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.031
Ubtf upstream binding transcription factor, RNA polymerase I 0.031
Cdca7 cell division cycle associated 7 0.031
Dhfr dihydrofolate reductase 0.031
Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) 0.031
Tollip toll interacting protein 0.031
March8 membrane-associated ring finger (C3HC4) 8 0.030
Mcm7 minichromosome maintenance complex component 7 0.030
Prc1 protein regulator of cytokinesis 1 0.029
Mki67 antigen identified by monoclonal antibody Ki-67 0.029
Ireb2 iron responsive element binding protein 2 0.029
Ccna2 cyclin A2 0.029
Tubg1 tubulin, gamma 1 0.028
Ube2i ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.028
Mybl2 myeloblastosis oncogene-like 2 0.028
Mapk6 mitogen-activated protein kinase 6 0.028
Asf1b ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 0.028
Necap2 NECAP endocytosis associated 2 0.027
Hmgb2 high mobility group box 2 0.027
Rpa2 replication protein A2 0.027
Arhgef1 Rho guanine nucleotide exchange factor (GEF) 1 0.027
Ect2 epithelial cell transforming sequence 2 oncogene 0.027
Tcp11l2 t-complex 11 (mouse) like 2 0.027
Tob1 transducer of ErbB-2.1 0.027
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.026
Fen1 flap structure-specific endonuclease 1 0.026
Arnt aryl hydrocarbon receptor nuclear translocator 0.026
Coro1b coronin, actin-binding protein, 1B 0.026
Stxbp3 syntaxin binding protein 3 0.026
Ska1 spindle and kinetochore associated complex subunit 1 0.026
LOC689399 hypothetical protein LOC689399 0.026
Eif4a2 eukaryotic translation initiation factor 4A, isoform 2 0.025
Daxx death-domain associated protein 0.025
Whsc2 Wolf-Hirschhorn syndrome candidate 2 (human) 0.025
Mapk7 mitogen-activated protein kinase 7 0.025
Ccnd3 cyclin D3 0.025
Pdp1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.025
Lmnb1 lamin B1 0.025
Epn1 Epsin 1 0.025
Cenpe centromere protein E 0.025
Cbl Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.025
Ythdf3 YTH domain family, member 3 0.025
Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.025
Lsm2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.024
Brca2 breast cancer 2 0.024
Ppm1b protein phosphatase 1B, magnesium dependent, beta isoform 0.024
Foxi2 forkhead box I2 0.024
Hprt1 hypoxanthine phosphoribosyltransferase 1 0.024
Cdca3 cell division cycle associated 3 0.024
Casp7 caspase 7 0.024
Depdc1 DEP domain containing 1 0.023
Lbr lamin B receptor 0.023
Ckap2 cytoskeleton associated protein 2 0.023
Gtf2i general transcription factor II I 0.023
Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 0.023
Dlg3 discs, large homolog 3 (Drosophila) 0.023
Adrbk1 adrenergic, beta, receptor kinase 1 0.023
Rfc1 replication factor C (activator 1) 1 0.023
Mapkapk3 mitogen-activated protein kinase-activated protein kinase 3 0.023
Lsm14a LSM14A, SCD6 homolog A (S. cerevisiae) 0.023
Rara retinoic acid receptor, alpha 0.023
Creb1 cAMP responsive element binding protein 1 0.022
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
GLC7 Glc7p 0.979
KEL1 Kel1p 0.849
HHT1 Hht1p 0.802
CDC28 Cdc28p 0.747
RAD53 Rad53p 0.667
PPH22 Pph22p 0.608
CLB3 Clb3p 0.597
DBF4 Dbf4p 0.535
CDC55 Cdc55p 0.519
RTS1 Rts1p 0.502
BUB3 Bub3p 0.498
CLB5 Clb5p 0.414
MCM10 Mcm10p 0.403
BMH1 Bmh1p 0.363
RAD9 Rad9p 0.361
POL30 Pol30p 0.360
PSR2 Psr2p 0.328
PPH21 Pph21p 0.321
GIC1 Gic1p 0.319
SLI15 Sli15p 0.309
CLB4 Clb4p 0.307
MAD2 Mad2p 0.299
HHF2 Hhf2p 0.294
MEC1 Mec1p 0.283
RRM3 Rrm3p 0.277
IML3 Iml3p 0.273
NBL1 Nbl1p 0.263
SET1 Set1p 0.244
BFA1 Bfa1p 0.223
SLK19 Slk19p 0.215
BIM1 Bim1p 0.214
CDC14 Cdc14p 0.213
GBP2 Gbp2p 0.193
BUB1 Bub1p 0.191
CDC20 Cdc20p 0.185
BEM3 Bem3p 0.180
KIC1 Kic1p 0.177
RPB3 Rpb3p 0.177
ZDS1 Zds1p 0.174
DPB2 Dpb2p 0.168
PSR1 Psr1p 0.166
SIC1 Sic1p 0.160
RCO1 Rco1p 0.158
PLC1 Plc1p 0.154
CBF2 Cbf2p 0.154
CKA1 Cka1p 0.150
CTF18 Ctf18p 0.149
RAD54 Rad54p 0.149
CDC12 Cdc12p 0.149
TID3 Tid3p 0.148
MAD3 Mad3p 0.147
MCM4 Mcm4p 0.146
RAD50 Rad50p 0.145
PEX22 Pex22p 0.139
CTF13 Ctf13p 0.137
TPD3 Tpd3p 0.134
SPT16 Spt16p 0.134
RIF1 Rif1p 0.133
RSC2 Rsc2p 0.131
SPT5 Spt5p 0.127
NUD1 Nud1p 0.127
ASE1 Ase1p 0.126
THO2 Tho2p 0.123
CLF1 Clf1p 0.121
PDS1 Pds1p 0.121
MCM21 Mcm21p 0.120
EAF1 Eaf1p 0.118
SLD3 Sld3p 0.117
RAD52 Rad52p 0.115
DMA2 Dma2p 0.115
CLB6 Clb6p 0.114
BUB2 Bub2p 0.114
LTE1 Lte1p 0.113
CDC25 Cdc25p 0.113
FAR1 Far1p 0.112
CTF4 Ctf4p 0.111
RFA1 Rfa1p 0.111
CWC2 Cwc2p 0.106
SMC4 Smc4p 0.105
RTT107 Rtt107p 0.101
PIK1 Pik1p 0.101
KIN3 Kin3p 0.099
MCM6 Mcm6p 0.098
LCD1 Lcd1p 0.095
SCC2 Scc2p 0.095
BMH2 Bmh2p 0.094
MRC1 Mrc1p 0.092
ELG1 Elg1p 0.092
SMT3 Smt3p 0.091
TFG1 Tfg1p 0.089
BNI4 Bni4p 0.089
REG1 Reg1p 0.088
UBP8 Ubp8p 0.088
PIR1 Pir1p 0.087
POL1 Pol1p 0.087
STU1 Stu1p 0.086
NOP6 Nop6p 0.086
CLB1 Clb1p 0.086
POL2 Pol2p 0.086
ADA2 Ada2p 0.083