The network for 'dorsal closure' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

dorsal closure

The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.

Drosophila melanogaster
Name Description Probability Func Analog Organism
Rho1 CG8416 gene product from transcript CG8416-RB 1.000
bsk basket 1.000
Rac1 CG2248 gene product from transcript CG2248-RA 0.999
cno canoe 0.997
msn misshapen 0.994
Src42A Src oncogene at 42A 0.991
mys myospheroid 0.989
shn schnurri 0.983
zip zipper 0.973
baz bazooka 0.965
if inflated 0.960
ci cubitus interruptus 0.956
par-1 CG8201 gene product from transcript CG8201-RA 0.950
Dad Daughters against dpp 0.931
puc puckered 0.927
Moe Moesin 0.924
raw CG12437 gene product from transcript CG12437-RB 0.923
R Roughened 0.914
cv-c crossveinless c 0.901
scb scab 0.896
Gprk2 G protein-coupled receptor kinase 2 0.893
Dhc64C Dynein heavy chain 64C 0.888
Mcr Macroglobulin complement-related 0.881
dia diaphanous 0.881
cbt cabut 0.878
mew multiple edematous wings 0.850
Cyp12d1-p CG30489 gene product from transcript CG30489-RA 0.845
dib disembodied 0.835
Phm Peptidylglycine-alpha-hydroxylating monooxygenase 0.811
tkv thickveins 0.786
LanA Laminin A 0.780
rib ribbon 0.765
sd scalloped 0.764
ush u-shaped 0.761
hep hemipterous 0.753
Cdc42 CG12530 gene product from transcript CG12530-RA 0.747
Gap1 GTPase-activating protein 1 0.741
Pkn Protein kinase related to protein kinase N 0.740
Egfr Epidermal growth factor receptor 0.734
pan pangolin 0.723
Jra Jun-related antigen 0.721
gho ghost 0.714
exu exuperantia 0.713
N Notch 0.710
ena enabled 0.701
rok Rho-kinase 0.699
fz2 frizzled 2 0.697
hh hedgehog 0.680
spo spook 0.679
Rala Ras-related protein 0.654
mmy mummy 0.643
crb crumbs 0.609
fkh fork head 0.597
srp serpent 0.596
Myo31DF Myosin 31DF 0.583
cora coracle 0.580
nmo nemo 0.572
pnr pannier 0.570
shg shotgun 0.546
Pi3K68D Phosphotidylinositol 3 kinase 68D 0.539
Mad Mothers against dpp 0.520
cindr CIN85 and CD2AP orthologue 0.514
wun wunen 0.511
e(y)3 enhancer of yellow 3 0.505
dsh dishevelled 0.503
p120ctn Adherens junction protein p120 0.500
arm armadillo 0.493
Abl Abl tyrosine kinase 0.488
Nrx-IV Neurexin IV 0.485
aop anterior open 0.461
sad shadow 0.455
hbs hibris 0.448
sdt stardust 0.431
dlp dally-like 0.424
Cyp12d1-d CG33503 gene product from transcript CG33503-RA 0.423
Pak PAK-kinase 0.411
rho rhomboid 0.395
htl heartless 0.388
pyd polychaetoid 0.387
bowl brother of odd with entrails limited 0.387
Fas2 Fasciclin 2 0.369
dlg1 discs large 1 0.365
vri vrille 0.359
yrt yurt 0.356
por porcupine 0.356
rst roughest 0.348
shd shade 0.348
jar jaguar 0.348
l(2)gl lethal (2) giant larvae 0.341
tup tailup 0.339
odd odd skipped 0.333
shot short stop 0.330
rin rasputin 0.329
Sdc Syndecan 0.322
Mef2 Myocyte enhancer factor 2 0.316
krz kurtz 0.313
cdi center divider 0.311
fz frizzled 0.307
Btk29A Btk family kinase at 29A 0.304
insc inscuteable 0.289
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism