The network for 'positive regulation of release of sequestered calcium ion into cytosol' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of release of sequestered calcium ion into cytosol

Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.

Name Description Probability Func Analog Organism
IL8 interleukin 8 0.999
CCR5 chemokine (C-C motif) receptor 5 0.999
CCL5 chemokine (C-C motif) ligand 5 0.997
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.995
CXCL9 chemokine (C-X-C motif) ligand 9 0.979
CCL4 chemokine (C-C motif) ligand 4 0.911
CXCL2 chemokine (C-X-C motif) ligand 2 0.904
CXCL3 chemokine (C-X-C motif) ligand 3 0.899
IL1B interleukin 1, beta 0.878
CXCL10 chemokine (C-X-C motif) ligand 10 0.866
CCL20 chemokine (C-C motif) ligand 20 0.853
MPDZ multiple PDZ domain protein 0.836
IL6 interleukin 6 (interferon, beta 2) 0.781
CCL2 chemokine (C-C motif) ligand 2 0.762
CXCL5 chemokine (C-X-C motif) ligand 5 0.745
CCL22 chemokine (C-C motif) ligand 22 0.743
CCL8 chemokine (C-C motif) ligand 8 0.742
CXCL11 chemokine (C-X-C motif) ligand 11 0.661
IFNG interferon, gamma 0.561
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.468
CCL7 chemokine (C-C motif) ligand 7 0.455
CCR2 chemokine (C-C motif) receptor 2 0.436
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.395
TTN titin 0.331
CCR7 chemokine (C-C motif) receptor 7 0.292
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.284
RGS1 regulator of G-protein signaling 1 0.282
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.278
CCL13 chemokine (C-C motif) ligand 13 0.268
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.251
DPP4 dipeptidyl-peptidase 4 0.250
IL2RB interleukin 2 receptor, beta 0.247
CCL3 chemokine (C-C motif) ligand 3 0.243
CXCL13 chemokine (C-X-C motif) ligand 13 0.225
CXCR3 chemokine (C-X-C motif) receptor 3 0.176
TNF tumor necrosis factor 0.148
IL10 interleukin 10 0.146
CCR4 chemokine (C-C motif) receptor 4 0.135
CCL19 chemokine (C-C motif) ligand 19 0.125
CLEC7A C-type lectin domain family 7, member A 0.125
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.123
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.122
PSEN2 presenilin 2 (Alzheimer disease 4) 0.113
PTEN phosphatase and tensin homolog 0.111
BAK1 BCL2-antagonist/killer 1 0.106
CCL11 chemokine (C-C motif) ligand 11 0.094
SOD2 superoxide dismutase 2, mitochondrial 0.093
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.082
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.080
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.075
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.075
GRB2 growth factor receptor-bound protein 2 0.075
CD22 CD22 molecule 0.074
MMP12 matrix metallopeptidase 12 (macrophage elastase) 0.073
IRF4 interferon regulatory factor 4 0.070
BCL2A1 BCL2-related protein A1 0.068
IL1R2 interleukin 1 receptor, type II 0.062
SLAMF7 SLAM family member 7 0.057
SH3BP2 SH3-domain binding protein 2 0.056
ALB albumin 0.056
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.053
LTA lymphotoxin alpha (TNF superfamily, member 1) 0.052
UBD ubiquitin D 0.051
PF4 platelet factor 4 0.049
SELE selectin E 0.049
CXCR6 chemokine (C-X-C motif) receptor 6 0.049
SNCAIP synuclein, alpha interacting protein 0.045
VCAM1 vascular cell adhesion molecule 1 0.042
CH25H cholesterol 25-hydroxylase 0.040
SSTR3 somatostatin receptor 3 0.040
CCR3 chemokine (C-C motif) receptor 3 0.039
LAMP3 lysosomal-associated membrane protein 3 0.039
PLEK pleckstrin 0.039
CXCR5 chemokine (C-X-C motif) receptor 5 0.037
CD83 CD83 molecule 0.035
CCR1 chemokine (C-C motif) receptor 1 0.034
RNR2 l-rRNA 0.034
BCL2L1 BCL2-like 1 0.034
BAD BCL2-associated agonist of cell death 0.034
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.034
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 0.033
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.033
CD40LG CD40 ligand 0.032
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.031
IL18RAP interleukin 18 receptor accessory protein 0.031
CD79A CD79a molecule, immunoglobulin-associated alpha 0.031
CXCR2 chemokine (C-X-C motif) receptor 2 0.031
MAPT microtubule-associated protein tau 0.029
FPR3 formyl peptide receptor 3 0.028
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.028
IL7R interleukin 7 receptor 0.028
RNF144B ring finger protein 144B 0.028
AQP9 aquaporin 9 0.028
MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 0.028
IL1A interleukin 1, alpha 0.028
IL16 interleukin 16 (lymphocyte chemoattractant factor) 0.027
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.027
IDO1 indoleamine 2,3-dioxygenase 1 0.027
ADAMDEC1 ADAM-like, decysin 1 0.027
C1orf93 chromosome 1 open reading frame 93 0.025
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Prdx1 peroxiredoxin 1 0.019
P2ry14 purinergic receptor P2Y, G-protein coupled, 14 0.017
Slco2b1 solute carrier organic anion transporter family, member 2b1 0.017
Xcl1 chemokine (C motif) ligand 1 0.012
Calcrl calcitonin receptor-like 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism