The network for 'positive regulation of response to biotic stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of response to biotic stimulus

Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus.

Homo sapiens
Name Description Probability Func Analog Organism
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.957
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.605
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.504
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.458
REL v-rel reticuloendotheliosis viral oncogene homolog (avian) 0.409
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.346
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.323
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.213
TLR4 toll-like receptor 4 0.127
IL8 interleukin 8 0.127
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.125
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.104
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.082
NCF1 neutrophil cytosolic factor 1 0.081
TNIP2 TNFAIP3 interacting protein 2 0.074
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.072
MED15 mediator complex subunit 15 0.067
PAX3 paired box 3 0.065
CHUK conserved helix-loop-helix ubiquitous kinase 0.059
LY96 lymphocyte antigen 96 0.055
CXCL3 chemokine (C-X-C motif) ligand 3 0.050
IFI16 interferon, gamma-inducible protein 16 0.046
TRIM22 tripartite motif containing 22 0.039
TRIM5 tripartite motif containing 5 0.037
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.037
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.036
TRIM39 tripartite motif containing 39 0.035
IL23A interleukin 23, alpha subunit p19 0.035
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.033
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.029
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 0.021
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.020
SP100 SP100 nuclear antigen 0.020
TLR1 toll-like receptor 1 0.019
NLRC4 NLR family, CARD domain containing 4 0.019
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) 0.019
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.018
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.018
PVRL4 poliovirus receptor-related 4 0.017
SAMD9 sterile alpha motif domain containing 9 0.017
NMI N-myc (and STAT) interactor 0.017
ZNF263 zinc finger protein 263 0.016
TLR2 toll-like receptor 2 0.016
MYD88 myeloid differentiation primary response gene (88) 0.016
IFIH1 interferon induced with helicase C domain 1 0.015
ZNF473 zinc finger protein 473 0.013
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.013
SOX10 SRY (sex determining region Y)-box 10 0.013
MAPK8 mitogen-activated protein kinase 8 0.012
INADL InaD-like (Drosophila) 0.012
CAV1 caveolin 1, caveolae protein, 22kDa 0.012
IRAK3 interleukin-1 receptor-associated kinase 3 0.012
PRKCA protein kinase C, alpha 0.012
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.012
CTSS cathepsin S 0.011
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.011
IFI44 interferon-induced protein 44 0.011
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 0.011
GBP3 guanylate binding protein 3 0.010
LRDD leucine-rich repeats and death domain containing 0.010
TRIM25 tripartite motif containing 25 0.010
MR1 major histocompatibility complex, class I-related 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Rel Relish 0.999
PGRP-LC Peptidoglycan recognition protein LC 0.995
Spn27A Serpin 27A 0.839
PGRP-SD CG7496 gene product from transcript CG7496-RA 0.828
ird5 immune response deficient 5 0.737
grass Gram-positive Specific Serine protease 0.721
SPE Spatzle-Processing Enzyme 0.683
DptB Diptericin B 0.676
PGRP-SA Peptidoglycan recognition protein SA 0.635
AttA Attacin-A 0.520
Spn28D Serpin 28D 0.504
imd immune deficiency 0.457
Myd88 CG2078 gene product from transcript CG2078-RA 0.375
Spn1 Serine protease inhibitor 1 0.372
Irc Immune-regulated catalase 0.342
fon fondue 0.323
cact cactus 0.271
AttC Attacin-C 0.267
BG4 CG12297 gene product from transcript CG12297-RA 0.186
Sp7 Serine protease 7 0.183
pirk poor Imd response upon knock-in 0.158
Spn77Ba Serpin 77Ba 0.158
PGRP-SC1a CG14746 gene product from transcript CG14746-RA 0.156
Dredd Death related ced-3/Nedd2-like protein 0.142
IM18 Immune induced molecule 18 0.134
spz spatzle 0.131
GNBP3 Gram-negative bacteria binding protein 3 0.125
Nc Nedd2-like caspase 0.123
key kenny 0.120
nub nubbin 0.105
PGRP-SC1b CG8577 gene product from transcript CG8577-RA 0.104
GNBP1 Gram-negative bacteria binding protein 1 0.098
osk oskar 0.095
CG15917 CG15917 gene product from transcript CG15917-RA 0.093
upd2 unpaired 2 0.089
CG12766 CG12766 gene product from transcript CG12766-RA 0.083
CG9184 CG9184 gene product from transcript CG9184-RB 0.075
pie pineapple eye 0.073
upd3 unpaired 3 0.072
modSP modular serine protease 0.069
CG31038 CG31038 gene product from transcript CG31038-RA 0.063
Drs Drosomycin 0.062
ird1 immune response deficient 1 0.062
CG18594 CG18594 gene product from transcript CG18594-RA 0.054
l(3)mbn lethal (3) malignant blood neoplasm 0.053
CG7910 CG7910 gene product from transcript CG7910-RA 0.053
CG32185 CG32185 gene product from transcript CG32185-RA 0.052
psh persephone 0.046
Tl Toll 0.046
Glt Glutactin 0.043
CG42863 CG42863 gene product from transcript CG42863-RB 0.041
Krn Keren 0.041
Gr63a Gustatory receptor 63a 0.038
eater CG6124 gene product from transcript CG6124-RB 0.038
CG9691 CG9691 gene product from transcript CG9691-RB 0.037
PGRP-LB Peptidoglycan recognition protein LB 0.036
18w 18 wheeler 0.034
TepII Thiolester containing protein II 0.034
DNaseII Deoxyribonuclease II 0.034
Eip71CD Ecdysone-induced protein 28/29kD 0.033
spirit Serine Protease Immune Response Integrator 0.033
norpA no receptor potential A 0.032
CG8586 CG8586 gene product from transcript CG8586-RA 0.032
POSH Plenty of SH3s 0.032
CG4250 CG4250 gene product from transcript CG4250-RA 0.032
CG13641 CG13641 gene product from transcript CG13641-RA 0.031
dpn deadpan 0.031
Tak1 TGF-beta activated kinase 1 0.030
Tab2 TAK1-associated binding protein 2 0.030
nec necrotic 0.030
Mekk1 CG7717 gene product from transcript CG7717-RB 0.029
Duox Dual oxidase 0.029
CG9902 CG9902 gene product from transcript CG9902-RA 0.028
Obp99d Odorant-binding protein 99d 0.027
CecC Cecropin C 0.027
bbg big bang 0.026
CG13422 CG13422 gene product from transcript CG13422-RA 0.026
r2d2 CG7138 gene product from transcript CG7138-RB 0.026
AGO2 Argonaute 2 0.025
CG12496 CG12496 gene product from transcript CG12496-RA 0.025
CG10157 CG10157 gene product from transcript CG10157-RA 0.024
CG17086 CG17086 gene product from transcript CG17086-RA 0.024
Oat Ornithine aminotransferase precursor 0.024
CG1773 CG1773 gene product from transcript CG1773-RA 0.023
tna tonalli 0.023
Mtk Metchnikowin 0.022
Jupiter CG31363 gene product from transcript CG31363-RD 0.021
CG9631 CG9631 gene product from transcript CG9631-RA 0.021
CG31326 CG31326 gene product from transcript CG31326-RA 0.021
CG6361 CG6361 gene product from transcript CG6361-RA 0.021
PGRP-LE Peptidoglycan recognition protein LE 0.021
Sir2 CG5216 gene product from transcript CG5216-RA 0.021
Toll-7 CG8595 gene product from transcript CG8595-RA 0.021
Tsf1 Transferrin 1 0.020
gsb-n gooseberry-neuro 0.020
SpdS Spermidine Synthase 0.020
Lip3 CG8823 gene product from transcript CG8823-RA 0.020
TepIII Thiolester containing protein III 0.020
CG3239 CG3239 gene product from transcript CG3239-RB 0.020
CG16756 CG16756 gene product from transcript CG16756-RA 0.019
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Mus musculus
Name Description Probability Func Analog Organism
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.841
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.805
Tnf tumor necrosis factor 0.623
Myd88 myeloid differentiation primary response gene 88 0.528
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.409
Tlr4 toll-like receptor 4 0.383
Cd40 CD40 antigen 0.368
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.347
Ikbkg inhibitor of kappaB kinase gamma 0.343
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.313
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.266
Igh immunoglobulin heavy chain complex 0.263
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.164
Ikbkb inhibitor of kappaB kinase beta 0.151
Birc3 baculoviral IAP repeat-containing 3 0.129
Cd44 CD44 antigen 0.084
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.067
Mavs mitochondrial antiviral signaling protein 0.064
Btk Bruton agammaglobulinemia tyrosine kinase 0.060
Ticam1 toll-like receptor adaptor molecule 1 0.048
Cxcl2 chemokine (C-X-C motif) ligand 2 0.042
Ccl4 chemokine (C-C motif) ligand 4 0.035
Cyld cylindromatosis (turban tumor syndrome) 0.031
Il1rn interleukin 1 receptor antagonist 0.031
Il1b interleukin 1 beta 0.030
Nfkbie nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.029
Gbp3 guanylate binding protein 3 0.029
Il10 interleukin 10 0.027
Cdx2 caudal type homeobox 2 0.027
Socs1 suppressor of cytokine signaling 1 0.026
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.025
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.025
Nlrp3 NLR family, pyrin domain containing 3 0.024
Bcl3 B-cell leukemia/lymphoma 3 0.023
Mmp13 matrix metallopeptidase 13 0.022
Tlr2 toll-like receptor 2 0.022
Clec4d C-type lectin domain family 4, member d 0.021
Junb Jun-B oncogene 0.021
Cd14 CD14 antigen 0.021
Gdf15 growth differentiation factor 15 0.020
Rel reticuloendotheliosis oncogene 0.020
Ifng interferon gamma 0.019
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.019
Unc93b1 unc-93 homolog B1 (C. elegans) 0.018
Zbp1 Z-DNA binding protein 1 0.018
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.017
Il1r1 interleukin 1 receptor, type I 0.017
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.016
Ccl7 chemokine (C-C motif) ligand 7 0.016
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.014
Sykb spleen tyrosine kinase 0.014
Socs3 suppressor of cytokine signaling 3 0.014
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.014
2010106G01Rik RIKEN cDNA 2010106G01 gene 0.014
Pyhin1 pyrin and HIN domain family, member 1 0.013
Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.013
Tax1bp1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.013
Slamf8 SLAM family member 8 0.013
Atf3 activating transcription factor 3 0.013
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.012
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.012
Trp53 transformation related protein 53 0.012
Lyz2 lysozyme 2 0.012
Cd180 CD180 antigen 0.012
Ccl2 chemokine (C-C motif) ligand 2 0.012
Pycard PYD and CARD domain containing 0.012
Slfn4 schlafen 4 0.012
Irg1 immunoresponsive gene 1 0.012
Ly96 lymphocyte antigen 96 0.012
Clec4e C-type lectin domain family 4, member e 0.012
Mefv Mediterranean fever 0.012
Cd33 CD33 antigen 0.012
Il6 interleukin 6 0.012
2410004A20Rik RIKEN cDNA 2410004A20 gene 0.012
Bcl6 B-cell leukemia/lymphoma 6 0.012
Nfkbiz nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.011
Ifi44 interferon-induced protein 44 0.011
Il7 interleukin 7 0.011
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.011
D14Ertd668e DNA segment, Chr 14, ERATO Doi 668, expressed 0.011
Trp73 transformation related protein 73 0.011
Slfn8 schlafen 8 0.010
Traf2 TNF receptor-associated factor 2 0.010
Hsp90b1 heat shock protein 90, beta (Grp94), member 1 0.010
Casp1 caspase 1 0.010
Epsti1 epithelial stromal interaction 1 (breast) 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism