The network for 'ventral spinal cord development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

ventral spinal cord development

The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output.

Homo sapiens
Name Description Probability Func Analog Organism
NOTCH3 notch 3 1.000
NOTCH1 notch 1 0.997
GLI1 GLI family zinc finger 1 0.920
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.914
GFI1B growth factor independent 1B transcription repressor 0.866
SUFU suppressor of fused homolog (Drosophila) 0.836
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.796
JAG1 jagged 1 0.795
VAC14 Vac14 homolog (S. cerevisiae) 0.766
INSR insulin receptor 0.728
STK36 serine/threonine kinase 36 0.529
RCN3 reticulocalbin 3, EF-hand calcium binding domain 0.504
PTCH1 patched 1 0.501
NOTCH2 notch 2 0.455
MID1IP1 MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish)) 0.429
GRB10 growth factor receptor-bound protein 10 0.319
MAML1 mastermind-like 1 (Drosophila) 0.264
JAG2 jagged 2 0.243
PDX1 pancreatic and duodenal homeobox 1 0.235
SEC24D SEC24 family, member D (S. cerevisiae) 0.227
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.219
PEX26 peroxisomal biogenesis factor 26 0.216
LDB1 LIM domain binding 1 0.207
IRS1 insulin receptor substrate 1 0.199
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.171
QPRT quinolinate phosphoribosyltransferase 0.162
ZNF764 zinc finger protein 764 0.132
HOXD9 homeobox D9 0.124
GAB1 GRB2-associated binding protein 1 0.121
RAX retina and anterior neural fold homeobox 0.113
HOXD11 homeobox D11 0.109
ISL1 ISL LIM homeobox 1 0.109
LBX1 ladybird homeobox 1 0.109
VHL von Hippel-Lindau tumor suppressor 0.106
FGF3 fibroblast growth factor 3 0.099
LPHN1 latrophilin 1 0.099
TP73 tumor protein p73 0.092
GLIS3 GLIS family zinc finger 3 0.091
SOX1 SRY (sex determining region Y)-box 1 0.085
ZIC1 Zic family member 1 (odd-paired homolog, Drosophila) 0.084
HOXD12 homeobox D12 0.082
TNRC6B trinucleotide repeat containing 6B 0.079
TUBB2B tubulin, beta 2B 0.079
LMX1A LIM homeobox transcription factor 1, alpha 0.079
HOXC11 homeobox C11 0.077
MARCKSL1 MARCKS-like 1 0.077
FOXD3 forkhead box D3 0.077
HAND2 heart and neural crest derivatives expressed 2 0.076
GATA4 GATA binding protein 4 0.074
TAL1 T-cell acute lymphocytic leukemia 1 0.073
EGFL7 EGF-like-domain, multiple 7 0.071
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.071
ARHGAP22 Rho GTPase activating protein 22 0.068
LDB2 LIM domain binding 2 0.067
LTBP4 latent transforming growth factor beta binding protein 4 0.061
GADD45A growth arrest and DNA-damage-inducible, alpha 0.061
TCF4 transcription factor 4 0.060
NKX2-2 NK2 homeobox 2 0.059
MEGF6 multiple EGF-like-domains 6 0.058
NKX6-1 NK6 homeobox 1 0.057
XIAP X-linked inhibitor of apoptosis 0.057
BHLHE23 basic helix-loop-helix family, member e23 0.057
EIF2C1 eukaryotic translation initiation factor 2C, 1 0.056
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 0.055
PAX7 paired box 7 0.055
AMN amnionless homolog (mouse) 0.053
TCF21 transcription factor 21 0.053
GBX2 gastrulation brain homeobox 2 0.053
FOXL1 forkhead box L1 0.053
HOXC6 homeobox C6 0.053
NPAS1 neuronal PAS domain protein 1 0.051
LHX5 LIM homeobox 5 0.051
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 0.050
POU3F1 POU class 3 homeobox 1 0.050
EGFR epidermal growth factor receptor 0.048
PYY peptide YY 0.046
NOVA2 neuro-oncological ventral antigen 2 0.045
FEV FEV (ETS oncogene family) 0.045
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 0.044
GJA3 gap junction protein, alpha 3, 46kDa 0.044
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 0.044
POU4F3 POU class 4 homeobox 3 0.043
IRS2 insulin receptor substrate 2 0.043
LHX1 LIM homeobox 1 0.042
NEUROD1 neurogenic differentiation 1 0.040
PAX6 paired box 6 0.040
BZRAP1 benzodiazapine receptor (peripheral) associated protein 1 0.040
WNT10A wingless-type MMTV integration site family, member 10A 0.040
LHX3 LIM homeobox 3 0.040
NKX2-1 NK2 homeobox 1 0.038
POU3F3 POU class 3 homeobox 3 0.038
OLIG2 oligodendrocyte lineage transcription factor 2 0.038
HOXD3 homeobox D3 0.038
NELL1 NEL-like 1 (chicken) 0.037
MNX1 motor neuron and pancreas homeobox 1 0.037
EFNB2 ephrin-B2 0.037
FOXG1 forkhead box G1 0.037
SOX11 SRY (sex determining region Y)-box 11 0.036
FOXA2 forkhead box A2 0.036
CHRNA4 cholinergic receptor, nicotinic, alpha 4 0.036
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
notch1a notch homolog 1a 0.989
shha sonic hedgehog a 0.973
dcc deleted in colorectal carcinoma 0.927
flh floating head 0.925
nkx2.2a NK2 transcription factor related 2a 0.922
dla deltaA 0.897
gli2a GLI-Kruppel family member GLI2a 0.863
tbx20 T-box 20 0.855
rx3 retinal homeobox gene 3 0.849
cdx4 caudal type homeo box transcription factor 4 0.820
tbx2b T-box 2b 0.819
lhx5 LIM homeobox 5 0.806
foxa1 forkhead box A1 0.796
dld deltaD 0.788
pax6a paired box gene 6a 0.781
fezf2 FEZ family zinc finger 2 0.750
lhx2b LIM homeobox 2b 0.718
hnf1ba HNF1 homeobox Ba 0.717
lhx1a LIM homeobox 1a 0.709
olig2 oligodendrocyte lineage transcription factor 2 0.707
tbx1 T-box 1 0.700
isl1 islet1 0.674
otx2 orthodenticle homolog 2 0.667
nkx2.2b NK2 transcription factor related 2b 0.657
lhx3 LIM homeobox 3 0.648
ascl1a achaete-scute complex-like 1a (Drosophila) 0.629
six3b sine oculis homeobox homolog 3b 0.610
dab1b disabled homolog 1b (Drosophila) 0.595
nkx6.1 NK6 transcription factor related, locus 1 (Drosophila) 0.586
nkx2.1a NK2 homeobox 1a 0.556
ndr2 nodal-related 2 0.532
reln reelin 0.509
otpb orthopedia homolog b 0.491
barhl2 BarH-like 2 0.488
dlc deltaC 0.482
tal2 T-cell acute lymphocytic leukemia 2 0.470
hlxb9lb homeo box HB9 like b 0.453
evx1 even-skipped homeobox 1 0.433
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.423
isl2a islet2a 0.423
tbx24 T-box 24 0.421
gli1 GLI-Kruppel family member 1 0.412
neurog1 neurogenin 1 0.409
pax2a paired box gene 2a 0.406
dlb deltaB 0.392
gja3 gap junction protein, alpha 3 0.385
shhb sonic hedgehog b 0.385
gcm2 glial cells missing homolog 2 (Drosophila) 0.382
chd chordin 0.373
runx1 runt-related transcription factor 1 0.354
foxi1 forkhead box I1 0.340
tbx16 T-box gene 16 0.335
nr2e1 nuclear receptor subfamily 2, group E, member 1 0.328
hoxb1a homeo box B1a 0.326
nkx2.1b NK2 homeobox 1b 0.304
pax8 paired box gene 8 0.302
prl prolactin 0.300
apc adenomatosis polyposis coli 0.299
nkx2.5 NK2 transcription factor related 5 0.296
dbx1a developing brain homeobox 1a 0.285
gata3 GATA-binding protein 3 0.284
cc2d2a coiled-coil and C2 domain containing 2A 0.282
olig4 oligodendrocyte transcription factor 4 0.280
fgf3 fibroblast growth factor 3 0.273
jag1b jagged 1b 0.268
itgav integrin, alpha V 0.267
csnk1a1 casein kinase 1, alpha 1 0.266
foxg1a forkhead box G1a 0.262
gbx1 gastrulation brain homeobox 1 0.260
mib mind bomb 0.259
olig3 oligodendrocyte transcription factor 3 0.255
lhx1b LIM homeobox 1b 0.252
tgfb3 transforming growth factor, beta 3 0.236
foxa2 forkhead box A2 0.236
dlx6a distal-less homeobox gene 6a 0.230
gata2a GATA-binding protein 2a 0.227
pitx2 paired-like homeodomain transcription factor 2 0.226
prdm1a PR domain containing 1a, with ZNF domain 0.220
her1 hairy-related 1 0.219
th tyrosine hydroxylase 0.215
eng2b engrailed 2b 0.214
oprd1b opioid receptor, delta 1b 0.213
cdh2 cadherin 2, neuronal 0.208
ascl1b achaete-scute complex-like 1b (Drosophila) 0.207
ptch2 patched 2 0.206
tal1 T-cell acute lymphocytic leukemia 1 0.206
zfp36l1a zinc finger protein 36, C3H type-like 1a 0.203
dlx1a distal-less homeobox gene 1a 0.199
raraa retinoic acid receptor, alpha a 0.194
pcdh18b protocadherin 18b 0.191
hoxd11a homeo box D11a 0.188
cyp19a1b cytochrome P450, family 19, subfamily A, polypeptide 1b 0.185
arx aristaless related homeobox 0.185
si:dkeyp-63d11.7 si:dkeyp-63d11.7 0.175
sox10 SRY-box containing gene 10 0.170
prickle1b prickle homolog 1 (Drosophila) b 0.166
pou1f1 POU domain, class 1, transcription factor 1 0.166
msgn1 mesogenin 1 0.164
tshb thyroid stimulating hormone, beta subunit 0.162
vsx2 visual system homeobox 2 0.161
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Pitx2 paired-like homeodomain transcription factor 2 0.999
Otx2 orthodenticle homolog 2 (Drosophila) 0.995
Gli2 GLI-Kruppel family member GLI2 0.994
Gli3 GLI-Kruppel family member GLI3 0.994
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.993
Msx1 homeobox, msh-like 1 0.987
Foxg1 forkhead box G1 0.965
Pitx1 paired-like homeodomain transcription factor 1 0.957
Emx1 empty spiracles homolog 1 (Drosophila) 0.953
Pbx1 pre B-cell leukemia transcription factor 1 0.897
Phox2b paired-like homeobox 2b 0.890
Tcfap2a transcription factor AP-2, alpha 0.881
Isl1 ISL1 transcription factor, LIM/homeodomain 0.877
Sox9 SRY-box containing gene 9 0.875
Pax2 paired box gene 2 0.865
Hoxa1 homeobox A1 0.855
Hand1 heart and neural crest derivatives expressed transcript 1 0.853
Fgfr2 fibroblast growth factor receptor 2 0.852
Foxc2 forkhead box C2 0.795
Hoxa10 homeobox A10 0.794
Lmx1a LIM homeobox transcription factor 1 alpha 0.785
Nkx2-2 NK2 transcription factor related, locus 2 (Drosophila) 0.771
Hoxd3 homeobox D3 0.764
Tbx3 T-box 3 0.751
Tal1 T-cell acute lymphocytic leukemia 1 0.724
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.715
Fgf8 fibroblast growth factor 8 0.713
Hoxd9 homeobox D9 0.696
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.687
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.684
Meox2 mesenchyme homeobox 2 0.676
Hoxc6 homeobox C6 0.663
Hoxd10 homeobox D10 0.651
Hoxd13 homeobox D13 0.649
Tlx3 T-cell leukemia, homeobox 3 0.642
Gata4 GATA binding protein 4 0.619
Hhex hematopoietically expressed homeobox 0.608
Nkx3-2 NK3 homeobox 2 0.604
Pax3 paired box gene 3 0.583
Hand2 heart and neural crest derivatives expressed transcript 2 0.573
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.555
Hoxb6 homeobox B6 0.551
Wnt6 wingless-related MMTV integration site 6 0.540
Sox2 SRY-box containing gene 2 0.538
Emx2 empty spiracles homolog 2 (Drosophila) 0.533
Fgfr1 fibroblast growth factor receptor 1 0.530
Wt1 Wilms tumor 1 homolog 0.518
Lhx9 LIM homeobox protein 9 0.517
En1 engrailed 1 0.507
Uncx UNC homeobox 0.497
Neurog2 neurogenin 2 0.494
Chd7 chromodomain helicase DNA binding protein 7 0.492
Msx3 homeobox, msh-like 3 0.492
Hes1 hairy and enhancer of split 1 (Drosophila) 0.460
Nos3 nitric oxide synthase 3, endothelial cell 0.457
Fgf10 fibroblast growth factor 10 0.453
Wnt3a wingless-related MMTV integration site 3A 0.442
Hoxc4 homeobox C4 0.442
Hoxa11 homeobox A11 0.440
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.431
Pax7 paired box gene 7 0.410
Nog noggin 0.405
Sox17 SRY-box containing gene 17 0.399
Foxc1 forkhead box C1 0.399
Nr2e1 nuclear receptor subfamily 2, group E, member 1 0.391
Eya1 eyes absent 1 homolog (Drosophila) 0.384
Chrd chordin 0.379
Wnt1 wingless-related MMTV integration site 1 0.372
Shh sonic hedgehog 0.361
Rarb retinoic acid receptor, beta 0.360
Hoxb2 homeobox B2 0.359
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.358
Phox2a paired-like homeobox 2a 0.352
Gdnf glial cell line derived neurotrophic factor 0.350
Hoxd1 homeobox D1 0.339
Nhlh1 nescient helix loop helix 1 0.339
Efnb2 ephrin B2 0.338
Fgf15 fibroblast growth factor 15 0.337
Sall3 sal-like 3 (Drosophila) 0.333
Ebf3 early B-cell factor 3 0.331
Hoxb3 homeobox B3 0.331
Hoxa5 homeobox A5 0.317
Foxh1 forkhead box H1 0.315
Hoxa4 homeobox A4 0.311
Ptf1a pancreas specific transcription factor, 1a 0.311
Pax6 paired box gene 6 0.305
Ret ret proto-oncogene 0.301
Hoxa2 homeobox A2 0.301
Gata3 GATA binding protein 3 0.301
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.298
Hoxb4 homeobox B4 0.288
Tlx2 T-cell leukemia, homeobox 2 0.288
Pax8 paired box gene 8 0.287
Hoxd11 homeobox D11 0.286
Msx2 homeobox, msh-like 2 0.281
Hoxc8 homeobox C8 0.278
Hoxd8 homeobox D8 0.278
She src homology 2 domain-containing transforming protein E 0.274
Foxp1 forkhead box P1 0.273
Lhx1 LIM homeobox protein 1 0.264
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Rattus norvegicus
Name Description Probability Func Analog Organism
St18 suppression of tumorigenicity 18 0.023
Nrarp Notch-regulated ankyrin repeat protein 0.022
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.021
Ucn2 urocortin 2 0.020
LOC100362814 hypothetical protein LOC100362814 0.019
LOC100364352 cytochrome P450, family 2, subfamily b, polypeptide 9-like 0.018
Lhx1 LIM homeobox 1 0.017
Znf76 zinc finger protein 76 (expressed in testis) 0.017
Gast gastrin 0.017
Esr2 estrogen receptor 2 (ER beta) 0.017
Gjd2 gap junction protein, delta 2 0.017
Kcnc3 potassium voltage gated channel, Shaw-related subfamily, member 3 0.017
Tmod2 tropomodulin 2 0.016
Spag4 sperm associated antigen 4 0.016
Tnr tenascin R 0.015
Cel carboxyl ester lipase 0.015
Pou2f2 POU class 2 homeobox 2 0.014
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.014
Prlh prolactin releasing hormone 0.014
Megf10 multiple EGF-like domains 10 0.014
B4galnt4 beta-1,4-N-acetyl-galactosaminyl transferase 4 0.014
Tcf4 transcription factor 4 0.013
Unc5b unc-5 homolog B (C. elegans) 0.013
Kcnh6 potassium voltage-gated channel, subfamily H (eag-related), member 6 0.013
Elavl4 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) 0.013
Itpr3 inositol 1,4,5-triphosphate receptor, type 3 0.013
Hapln4 hyaluronan and proteoglycan link protein 4 0.013
Dlg4 discs, large homolog 4 (Drosophila) 0.012
Olr825 olfactory receptor 825 0.012
Ddr1 discoidin domain receptor tyrosine kinase 1 0.012
Cfc1 cripto, FRL-1, cryptic family 1 0.012
Bdkrb2 bradykinin receptor B2 0.012
Sost sclerosteosis 0.012
Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 0.012
Gabrg3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.012
Shc2 SHC (Src homology 2 domain containing) transforming protein 2 0.012
Neurod2 neurogenic differentiation 2 0.012
Barhl2 BarH-like homeobox 2 0.012
Dll3 delta-like 3 (Drosophila) 0.012
Drp2 dystrophin related protein 2 0.012
Olr1356 olfactory receptor 1356 0.012
Trpm8 transient receptor potential cation channel, subfamily M, member 8 0.012
Nlgn2 neuroligin 2 0.011
LOC100360919 Immunoglobulin lambda-like polypeptide 1-like 0.011
Wfdc5 WAP four-disulfide core domain 5 0.011
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.011
Ncam1 neural cell adhesion molecule 1 0.011
Rps6ka1 ribosomal protein S6 kinase polypeptide 1 0.011
Hes3 hairy and enhancer of split 3 (Drosophila) 0.011
Slc28a1 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 0.011
Shank1 SH3 and multiple ankyrin repeat domains 1 0.011
Gper G protein-coupled estrogen receptor 1 0.011
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.011
Prm1 protamine 1 0.011
Mip major intrinsic protein of lens fiber 0.011
Camk2n2 calcium/calmodulin-dependent protein kinase II inhibitor 2 0.011
Fgf4 fibroblast growth factor 4 0.010
Sox12 SRY (sex determining region Y)-box 12 0.010
Tcof1 Treacher Collins-Franceschetti syndrome 1 homolog (human) 0.010
Iapp islet amyloid polypeptide 0.010
Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 0.010
Ptgir prostaglandin I2 (prostacyclin) receptor (IP) 0.010
Pitx3 paired-like homeodomain 3 0.010
P2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 0.010
Grk4 G protein-coupled receptor kinase 4 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism