The network for 'regulation of interferon beta biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of interferon beta biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-beta.

Homo sapiens
Name Description Probability Func Analog Organism
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 1.000
MYD88 myeloid differentiation primary response gene (88) 0.996
TANK TRAF family member-associated NFKB activator 0.995
AZI2 5-azacytidine induced 2 0.990
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.990
LY96 lymphocyte antigen 96 0.988
PIAS4 protein inhibitor of activated STAT, 4 0.977
IRF7 interferon regulatory factor 7 0.884
IRF3 interferon regulatory factor 3 0.779
TBK1 TANK-binding kinase 1 0.698
OPTN optineurin 0.635
TLR4 toll-like receptor 4 0.403
TLR1 toll-like receptor 1 0.313
TNIP1 TNFAIP3 interacting protein 1 0.298
HTT huntingtin 0.296
TADA3 transcriptional adaptor 3 0.256
MIB1 mindbomb homolog 1 (Drosophila) 0.216
TLR2 toll-like receptor 2 0.202
TICAM2 toll-like receptor adaptor molecule 2 0.157
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.148
TRAF3 TNF receptor-associated factor 3 0.137
TBC1D17 TBC1 domain family, member 17 0.102
PRKD2 protein kinase D2 0.083
BAX BCL2-associated X protein 0.074
VNN2 vanin 2 0.060
NUP62 nucleoporin 62kDa 0.058
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 0.056
GTF2B general transcription factor IIB 0.052
CYLD cylindromatosis (turban tumor syndrome) 0.052
TFEC transcription factor EC 0.049
IGSF6 immunoglobulin superfamily, member 6 0.042
CCT8 chaperonin containing TCP1, subunit 8 (theta) 0.038
BTK Bruton agammaglobulinemia tyrosine kinase 0.036
TLR6 toll-like receptor 6 0.030
MAFB v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) 0.030
CCR1 chemokine (C-C motif) receptor 1 0.029
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.028
IRAK3 interleukin-1 receptor-associated kinase 3 0.028
ANAPC2 anaphase promoting complex subunit 2 0.028
TNIP2 TNFAIP3 interacting protein 2 0.027
PIK3CG phosphoinositide-3-kinase, catalytic, gamma polypeptide 0.026
HSPH1 heat shock 105kDa/110kDa protein 1 0.024
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.024
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.023
FOXO1 forkhead box O1 0.022
SLFN12 schlafen family member 12 0.021
KIAA1274 KIAA1274 0.021
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.020
CALCOCO2 calcium binding and coiled-coil domain 2 0.020
EVI2B ecotropic viral integration site 2B 0.019
ANKRD28 ankyrin repeat domain 28 0.019
FOXO3 forkhead box O3 0.019
ZNF267 zinc finger protein 267 0.018
NCOA6 nuclear receptor coactivator 6 0.018
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.017
CD28 CD28 molecule 0.017
IRAK4 interleukin-1 receptor-associated kinase 4 0.017
EVI2A ecotropic viral integration site 2A 0.017
TRAF2 TNF receptor-associated factor 2 0.016
TRIM21 tripartite motif containing 21 0.015
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.015
MPEG1 macrophage expressed 1 0.014
MARCH1 membrane-associated ring finger (C3HC4) 1 0.014
MCTP1 multiple C2 domains, transmembrane 1 0.014
IRF5 interferon regulatory factor 5 0.014
MAVS mitochondrial antiviral signaling protein 0.013
CYB5R4 cytochrome b5 reductase 4 0.013
MSR1 macrophage scavenger receptor 1 0.013
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.013
TLR7 toll-like receptor 7 0.013
NCOA2 nuclear receptor coactivator 2 0.012
C17orf60 chromosome 17 open reading frame 60 0.012
MOGS mannosyl-oligosaccharide glucosidase 0.012
EIF2C2 eukaryotic translation initiation factor 2C, 2 0.012
STAP2 signal transducing adaptor family member 2 0.012
TBKBP1 TBK1 binding protein 1 0.012
CLTC clathrin, heavy chain (Hc) 0.012
PTAFR platelet-activating factor receptor 0.012
GPR34 G protein-coupled receptor 34 0.011
TLR5 toll-like receptor 5 0.011
CYSLTR1 cysteinyl leukotriene receptor 1 0.011
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.011
IGJ immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides 0.011
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.011
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) 0.011
BST1 bone marrow stromal cell antigen 1 0.011
MS4A7 membrane-spanning 4-domains, subfamily A, member 7 0.011
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
rhoub ras homolog gene family, member Ub 0.012
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Ikbkg inhibitor of kappaB kinase gamma 0.999
Myd88 myeloid differentiation primary response gene 88 0.999
Chuk conserved helix-loop-helix ubiquitous kinase 0.984
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.824
Sfpi1 SFFV proviral integration 1 0.801
Ccr2 chemokine (C-C motif) receptor 2 0.760
Tlr4 toll-like receptor 4 0.714
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.661
Ticam1 toll-like receptor adaptor molecule 1 0.653
Stat1 signal transducer and activator of transcription 1 0.622
Stat2 signal transducer and activator of transcription 2 0.592
Cd44 CD44 antigen 0.475
Tax1bp1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.390
Birc3 baculoviral IAP repeat-containing 3 0.361
Ifnar1 interferon (alpha and beta) receptor 1 0.357
1810019J16Rik RIKEN cDNA 1810019J16 gene 0.355
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.342
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.293
Irak4 interleukin-1 receptor-associated kinase 4 0.265
Il10 interleukin 10 0.221
Uba7 ubiquitin-like modifier activating enzyme 7 0.220
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.206
Ccl2 chemokine (C-C motif) ligand 2 0.200
Trim21 tripartite motif-containing 21 0.186
Stat6 signal transducer and activator of transcription 6 0.174
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.156
Ifnar2 interferon (alpha and beta) receptor 2 0.154
Stat3 signal transducer and activator of transcription 3 0.154
Cd14 CD14 antigen 0.138
Cblb Casitas B-lineage lymphoma b 0.122
Tank TRAF family member-associated Nf-kappa B activator 0.120
Tnf tumor necrosis factor 0.115
Sykb spleen tyrosine kinase 0.113
Cd180 CD180 antigen 0.107
Ly96 lymphocyte antigen 96 0.095
Irf5 interferon regulatory factor 5 0.088
Unc93b1 unc-93 homolog B1 (C. elegans) 0.088
Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 0.085
Mmp9 matrix metallopeptidase 9 0.085
Irgm2 immunity-related GTPase family M member 2 0.083
Parp14 poly (ADP-ribose) polymerase family, member 14 0.081
Ikbkb inhibitor of kappaB kinase beta 0.076
Tor3a torsin family 3, member A 0.075
H2-DMb2 histocompatibility 2, class II, locus Mb2 0.071
Usp18 ubiquitin specific peptidase 18 0.070
Ddx58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.069
Wsb1 WD repeat and SOCS box-containing 1 0.063
Igtp interferon gamma induced GTPase 0.063
Traf6 TNF receptor-associated factor 6 0.062
Samhd1 SAM domain and HD domain, 1 0.061
Ncoa3 nuclear receptor coactivator 3 0.061
Sp100 nuclear antigen Sp100 0.061
Il10ra interleukin 10 receptor, alpha 0.059
Ergic2 ERGIC and golgi 2 0.058
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.058
Stxbp3a syntaxin binding protein 3A 0.055
Fas Fas (TNF receptor superfamily member 6) 0.055
Tnfrsf13b tumor necrosis factor receptor superfamily, member 13b 0.055
Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 0.053
Ifit3 interferon-induced protein with tetratricopeptide repeats 3 0.052
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.052
Tapbp TAP binding protein 0.052
Cd300ld CD300 molecule-like family member d 0.051
Tlr9 toll-like receptor 9 0.051
Tlr6 toll-like receptor 6 0.049
Ly86 lymphocyte antigen 86 0.046
Spp1 secreted phosphoprotein 1 0.046
Azi2 5-azacytidine induced gene 2 0.045
Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) 0.045
Il1r1 interleukin 1 receptor, type I 0.044
Rnpc3 RNA-binding region (RNP1, RRM) containing 3 0.044
Mib1 mindbomb homolog 1 (Drosophila) 0.044
Hpgds hematopoietic prostaglandin D synthase 0.042
Itgal integrin alpha L 0.041
Klra9 killer cell lectin-like receptor subfamily A, member 9 0.040
Tlr5 toll-like receptor 5 0.040
Naip6 NLR family, apoptosis inhibitory protein 6 0.039
Mavs mitochondrial antiviral signaling protein 0.039
Epsti1 epithelial stromal interaction 1 (breast) 0.039
Tbk1 TANK-binding kinase 1 0.039
BC006779 cDNA sequence BC006779 0.038
Tlr1 toll-like receptor 1 0.037
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.037
Tmem173 transmembrane protein 173 0.036
Gpr35 G protein-coupled receptor 35 0.036
Traf3ip2 TRAF3 interacting protein 2 0.036
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.036
Parp10 poly (ADP-ribose) polymerase family, member 10 0.036
Il27ra interleukin 27 receptor, alpha 0.035
Apobec1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 0.034
Adar adenosine deaminase, RNA-specific 0.033
Pyhin1 pyrin and HIN domain family, member 1 0.029
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.029
Ifng interferon gamma 0.029
Tmem106a transmembrane protein 106A 0.029
Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.029
Ms4a4c membrane-spanning 4-domains, subfamily A, member 4C 0.028
Ifi203 interferon activated gene 203 0.028
Ifih1 interferon induced with helicase C domain 1 0.027
Csprs component of Sp100-rs 0.027
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism