The network for 'enzyme linked receptor protein signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

enzyme linked receptor protein signaling pathway

Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with regulation of a downstream cellular process, e.g. transcription.

Rattus norvegicus
Name Description Probability Func Analog Organism
Grm5 glutamate receptor, metabotropic 5 0.811
Gata6 GATA binding protein 6 0.754
Jak2 Janus kinase 2 0.743
S1pr2 sphingosine-1-phosphate receptor 2 0.741
Smad3 SMAD family member 3 0.725
Irs1 insulin receptor substrate 1 0.722
Grb2 growth factor receptor bound protein 2 0.711
Fgfr2 fibroblast growth factor receptor 2 0.688
Npr3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) 0.667
Sirpa signal-regulatory protein alpha 0.663
Akt1 v-akt murine thymoma viral oncogene homolog 1 0.616
Grin2a glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.612
Irf2 interferon regulatory factor 2 0.607
Egfr epidermal growth factor receptor 0.591
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.575
Ppard peroxisome proliferator-activated receptor delta 0.574
Ncan neurocan 0.558
Jak1 Janus kinase 1 0.548
Flt1 FMS-related tyrosine kinase 1 0.519
Col5a2 collagen, type V, alpha 2 0.507
Dusp1 dual specificity phosphatase 1 0.498
Ghr growth hormone receptor 0.493
Met met proto-oncogene 0.487
Smad7 SMAD family member 7 0.469
Ednra endothelin receptor type A 0.465
Ddr2 discoidin domain receptor tyrosine kinase 2 0.462
Rara retinoic acid receptor, alpha 0.457
Trim47 tripartite motif-containing 47 0.449
Cish cytokine inducible SH2-containing protein 0.448
Itgb1 integrin, beta 1 0.442
Rcvrn recoverin 0.436
Pecam1 platelet/endothelial cell adhesion molecule 1 0.428
Egr1 early growth response 1 0.426
Prdm2 PR domain containing 2, with ZNF domain 0.426
Phkg1 phosphorylase kinase, gamma 1 0.425
Rac1 ras-related C3 botulinum toxin substrate 1 0.414
Rorb RAR-related orphan receptor B 0.409
Stk10 serine/threonine kinase 10 0.402
Agtr1a angiotensin II receptor, type 1a 0.390
Efnb1 ephrin B1 0.386
Btg2 BTG family, member 2 0.376
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.372
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.368
Bmp6 bone morphogenetic protein 6 0.357
Prrx1 paired related homeobox 1 0.351
Foxs1 forkhead box S1 0.348
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.345
Egr2 early growth response 2 0.344
Sox17 SRY (sex determining region Y)-box 17 0.342
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.333
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.330
Cast calpastatin 0.327
Syt8 synaptotagmin VIII 0.322
Robo1 roundabout homolog 1 (Drosophila) 0.316
Cntfr ciliary neurotrophic factor receptor 0.310
Fstl1 follistatin-like 1 0.308
Cpxm2 carboxypeptidase X (M14 family), member 2 0.297
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.297
Dusp6 dual specificity phosphatase 6 0.295
Smad1 SMAD family member 1 0.292
Snap91 synaptosomal-associated protein 91 0.291
Olfml2b olfactomedin-like 2B 0.285
Insr insulin receptor 0.284
Lnpep leucyl/cystinyl aminopeptidase 0.281
Glg1 golgi apparatus protein 1 0.281
Col1a1 collagen, type I, alpha 1 0.280
Gcm1 glial cells missing homolog 1 (Drosophila) 0.280
Lims1 LIM and senescent cell antigen-like domains 1 0.279
Gria2 glutamate receptor, ionotropic, AMPA 2 0.278
Acvr1 activin A receptor, type I 0.274
Stat5b signal transducer and activator of transcription 5B 0.272
Tgfb3 transforming growth factor, beta 3 0.270
Tgfbr3 transforming growth factor, beta receptor III 0.264
Bcl2 B-cell CLL/lymphoma 2 0.256
Inpp5d inositol polyphosphate-5-phosphatase D 0.253
Pde4b phosphodiesterase 4B, cAMP specific 0.253
Ryr2 ryanodine receptor 2, cardiac 0.253
Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.252
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.251
Ets1 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 0.245
Itpkb inositol 1,4,5-trisphosphate 3-kinase B 0.244
Usf2 upstream transcription factor 2, c-fos interacting 0.243
Irx4 iroquois homeobox 4 0.239
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.239
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.239
Ppfia4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 0.239
Wipf1 WAS/WASL interacting protein family, member 1 0.238
Hpcal4 hippocalcin-like 4 0.237
Ptafr platelet-activating factor receptor 0.236
Smek2 SMEK homolog 2, suppressor of mek1 (Dictyostelium) 0.235
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.234
Rassf5 Ras association (RalGDS/AF-6) domain family member 5 0.233
Nfasc neurofascin 0.230
Il1r1 interleukin 1 receptor, type I 0.228
Atf3 activating transcription factor 3 0.228
Lox lysyl oxidase 0.227
Arnt aryl hydrocarbon receptor nuclear translocator 0.227
Zfp36 zinc finger protein 36 0.226
Timp2 TIMP metallopeptidase inhibitor 2 0.225
Fgfr1 Fibroblast growth factor receptor 1 0.225
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-15 Protein EGL-15 0.913
nhr-67 Protein NHR-67 0.585
vab-3 Protein VAB-3 0.548
elt-6 Protein ELT-6 0.522
sem-5 Protein SEM-5 0.514
sma-6 Protein SMA-6 0.490
bar-1 Protein BAR-1 0.453
egl-8 Protein EGL-8 0.446
let-60 Protein LET-60 0.446
egl-18 Protein EGL-18 0.418
egl-13 Protein EGL-13 0.413
pry-1 Protein PRY-1 0.411
che-2 Protein CHE-2 0.384
eps-8 Protein EPS-8 0.374
hlh-30 Protein HLH-30 0.343
daf-1 Protein DAF-1 0.340
unc-6 Protein UNC-6 0.320
hlh-2 Protein HLH-2 0.317
unc-9 Protein UNC-9 0.303
plc-1 Protein PLC-1 0.273
che-13 Protein CHE-13 0.213
unc-94 Protein UNC-94 0.203
dlk-1 Protein DLK-1 0.198
daf-2 Protein DAF-2 0.184
ccch-1 Protein CCCH-1 0.178
pkg-1 Protein PKG-1 0.174
par-5 Protein PAR-5 0.166
pxf-1 Protein PXF-1 0.164
oac-46 Protein OAC-46 0.158
tax-4 Protein TAX-4 0.156
che-3 Protein CHE-3 0.150
osm-3 Protein OSM-3 0.148
unc-73 Protein UNC-73 0.147
dnc-2 Protein DNC-2 0.143
glo-4 Protein GLO-4 0.131
odr-3 Protein ODR-3 0.130
peb-1 Protein PEB-1 0.129
unc-83 Protein UNC-83 0.128
itr-1 Protein ITR-1 0.128
pha-4 Protein PHA-4 0.126
akt-1 Protein AKT-1 0.126
lag-1 Protein LAG-1 0.125
daf-11 Protein DAF-11 0.125
osm-6 Protein OSM-6 0.125
nipi-3 Protein NIPI-3 0.125
inx-3 Protein INX-3 0.122
ceh-20 Protein CEH-20 0.116
mes-4 Protein MES-4 0.115
unc-52 Protein UNC-52 0.110
egl-27 Protein EGL-27 0.109
gcy-22 Protein GCY-22 0.103
osm-5 Protein OSM-5 0.102
nhr-25 Protein NHR-25 0.101
cam-1 Protein CAM-1 0.095
ten-1 Protein TEN-1 0.094
brp-1 Protein BRP-1 0.092
egl-30 Protein EGL-30 0.090
cids-2 Protein CIDS-2 0.087
ape-1 Protein APE-1 0.086
ceh-44 Protein CEH-44 0.085
miz-1 Protein MIZ-1 0.084
pat-3 Protein PAT-3 0.083
mig-2 Protein MIG-2 0.082
nas-38 Protein NAS-38 0.079
cki-1 Protein CKI-1 0.079
unc-104 Protein UNC-104 0.078
hlh-1 Protein HLH-1 0.078
flt-1 Protein FLT-1 0.078
sel-12 Protein SEL-12 0.078
unc-43 Protein UNC-43 0.077
pdfr-1 Protein PDFR-1 0.073
trcs-2 Protein TRCS-2 0.072
erd-2 Protein ERD-2 0.071
hlh-14 Protein HLH-14 0.070
egl-44 Protein EGL-44 0.069
tag-123 Protein TAG-123 0.069
lin-29 Protein LIN-29 0.068
CELE_F54D5.5 Protein F54D5.5 0.067
nhr-45 Protein NHR-45 0.067
rme-4 Protein RME-4 0.066
efl-3 Protein EFL-3 0.066
sax-3 Protein SAX-3 0.065
mbk-2 Protein MBK-2 0.065
exc-5 Protein EXC-5 0.064
tag-196 Protein TAG-196 0.064
tag-320 Protein TAG-320 0.064
ing-3 Protein ING-3 0.064
frm-7 Protein FRM-7 0.064
daf-7 Protein DAF-7 0.064
wrn-1 Protein WRN-1 0.063
unc-62 Protein UNC-62 0.063
CELE_Y69A2AR.28 Protein Y69A2AR.28 0.063
lin-1 Protein LIN-1 0.063
ttm-1 Protein TTM-1 0.061
T28F4.1 Protein T28F4.1 0.061
C14B9.2 Protein C14B9.2 0.060
daf-19 Protein DAF-19 0.059
faah-1 Protein FAAH-1 0.058
lin-25 Protein LIN-25 0.058
daf-4 Protein DAF-4 0.057
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Danio rerio
Name Description Probability Func Analog Organism
chd chordin 0.999
fgf8a fibroblast growth factor 8 a 0.993
sox9a SRY-box containing gene 9a 0.983
shha sonic hedgehog a 0.967
ntla no tail a 0.947
plcg1 phospholipase C, gamma 1 0.940
tbx1 T-box 1 0.928
fgf3 fibroblast growth factor 3 0.926
ndr2 nodal-related 2 0.905
gli2a GLI-Kruppel family member GLI2a 0.896
lft1 lefty1 0.895
bmp4 bone morphogenetic protein 4 0.888
bmp2a bone morphogenetic protein 2a 0.883
lratb lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b) 0.858
twist3 twist3 0.837
bmp2b bone morphogenetic protein 2b 0.830
pcdh18b protocadherin 18b 0.813
wnt4a wingless-type MMTV integration site family, member 4a 0.729
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.722
tbx16 T-box gene 16 0.703
gli1 GLI-Kruppel family member 1 0.688
vcana versican a 0.674
dusp6 dual specificity phosphatase 6 0.661
fn1 fibronectin 1 0.656
raraa retinoic acid receptor, alpha a 0.647
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.640
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.613
s1pr2 sphingosine-1-phosphate receptor 2 0.611
notch1a notch homolog 1a 0.609
efnb2a ephrin B2a 0.592
vent ventral expressed homeobox 0.589
gpc4 glypican 4 0.586
notch3 notch homolog 3 0.580
gbx2 gastrulation brain homeo box 2 0.578
fzd10 frizzled homolog 10 0.570
ephb4b eph receptor B4b 0.564
smad9 MAD homolog 9 (Drosophila) 0.559
dlc deltaC 0.544
esr1 estrogen receptor 1 0.526
trim33 tripartite motif-containing 33 0.522
wnt5b wingless-type MMTV integration site family, member 5b 0.519
tie1 endothelium-specific receptor tyrosine kinase 1 0.511
gata4 GATA-binding protein 4 0.510
foxa3 forkhead box A3 0.509
rag1 recombination activating gene 1 0.501
cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 0.498
runx2b runt-related transcription factor 2b 0.497
spns2 spinster homolog 2 (Drosophila) 0.490
dlb deltaB 0.490
fsta follistatin a 0.478
wnt10a wingless-type MMTV integration site family, member 10a 0.467
fbn2b fibrillin 2b 0.466
sox7 SRY-box containing gene 7 0.465
foxi1 forkhead box I1 0.461
bmp7a bone morphogenetic protein 7a 0.460
zic3 zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila) 0.456
fgfr1b fibroblast growth factor receptor 1b 0.454
igf1rb insulin-like growth factor 1b receptor 0.454
nanos3 nanos homolog 3 0.449
zbtb4 zinc finger and BTB domain containing 4 0.447
tbx2a T-box gene 2a 0.444
sox19a SRY-box containing gene 19a 0.435
wnt8b wingless-type MMTV integration site family, member 8b 0.431
wnt11r wingless-type MMTV integration site family, member 11, related 0.417
sec23a Sec23 homolog A (S. cerevisiae) 0.414
cmyb transcription factor cmyb 0.400
tll1 tolloid-like 1 0.398
wnt11 wingless-type MMTV integration site family, member 11 0.397
pomca proopiomelanocortin a 0.396
mll myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.395
twist1a twist1a 0.391
egr1 early growth response 1 0.391
neo1 neogenin 1 0.388
nog2 noggin 2 0.385
eve1 even-skipped-like1 0.381
fras1 Fraser syndrome 1 0.379
ptch2 patched 2 0.377
ghra growth hormone receptor a 0.376
dcc deleted in colorectal carcinoma 0.375
eomesa eomesodermin homolog a 0.374
esr2a estrogen receptor 2a 0.373
wnt9a wingless-type MMTV integration site family, member 9A 0.363
pkd2 polycystic kidney disease 2 0.363
rarab retinoic acid receptor, alpha b 0.354
zgc:85866 zgc:85866 0.351
fgfr2 fibroblast growth factor receptor 2 0.351
hoxa13a homeo box A13a 0.345
spry4 sprouty (Drosophila) homolog 4 0.343
hhip hedgehog interacting protein 0.333
tp53bp2 tumor protein p53 binding protein, 2 0.326
cdh5 cadherin 5 0.326
fmr1 fragile X mental retardation 1 0.323
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.322
nrp2b neuropilin 2b 0.319
hs6st2 heparan sulfate 6-O-sulfotransferase 2 0.317
mecom MDS1 and EVI1 complex locus 0.317
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.315
tbx18 T-box 18 0.315
gbx1 gastrulation brain homeobox 1 0.312
ptk2.1 protein tyrosine kinase 2a 0.312
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Drosophila melanogaster
Name Description Probability Func Analog Organism
tkv thickveins 1.000
EcR Ecdysone receptor 0.996
drk downstream of receptor kinase 0.993
put punt 0.986
Egfr Epidermal growth factor receptor 0.984
l(2)gl lethal (2) giant larvae 0.983
kay kayak 0.982
rl rolled 0.981
InR Insulin-like receptor 0.975
babo baboon 0.965
hep hemipterous 0.961
phl pole hole 0.957
sax saxophone 0.949
csw corkscrew 0.948
mbc myoblast city 0.940
aux auxillin 0.940
Atg1 Autophagy-specific gene 1 0.937
eya eyes absent 0.936
sog short gastrulation 0.934
argos CG4531 gene product from transcript CG4531-RA 0.921
mys myospheroid 0.913
ci cubitus interruptus 0.912
Rac1 CG2248 gene product from transcript CG2248-RA 0.911
ex expanded 0.899
Ras85D Ras oncogene at 85D 0.887
chico CG5686 gene product from transcript CG5686-RB 0.881
Sulf1 Sulfated 0.876
nmo nemo 0.869
Mer Merlin 0.844
yki yorkie 0.834
ttv tout-velu 0.832
bowl brother of odd with entrails limited 0.828
ato atonal 0.817
Jra Jun-related antigen 0.810
rho rhomboid 0.803
pnt pointed 0.802
Src42A Src oncogene at 42A 0.793
Stat92E Signal-transducer and activator of transcription protein at 92E 0.785
park parkin 0.784
hpo hippo 0.781
spi spitz 0.768
htl heartless 0.760
Bre1 CG10542 gene product from transcript CG10542-RA 0.753
C3G CG42328 gene product from transcript CG42328-RC 0.750
kn knot 0.749
ash2 absent, small, or homeotic discs 2 0.748
arm armadillo 0.747
LanB1 CG7123 gene product from transcript CG7123-RA 0.743
Rab5 Rab-protein 5 0.742
puc puckered 0.726
aop anterior open 0.718
shi shibire 0.718
rst roughest 0.713
par-1 CG8201 gene product from transcript CG8201-RA 0.701
stumps CG31317 gene product from transcript CG31317-RC 0.701
so sine oculis 0.692
neur neuralized 0.687
wit wishful thinking 0.685
rictor rapamycin-insensitive companion of Tor 0.683
Psn Presenilin 0.661
fkh fork head 0.656
Dad Daughters against dpp 0.641
wls wntless 0.641
hth homothorax 0.640
bs blistered 0.637
sev sevenless 0.627
Rab7 Rab-protein 7 0.625
spen split ends 0.622
pyd polychaetoid 0.621
rpr reaper 0.621
shn schnurri 0.613
hipk homeodomain interacting protein kinase 0.608
Akt1 CG4006 gene product from transcript CG4006-RA 0.605
dm diminutive 0.604
Pten CG5671 gene product from transcript CG5671-RB 0.604
eve even skipped 0.601
salm spalt major 0.591
ab abrupt 0.580
S6k RPS6-p70-protein kinase 0.579
mew multiple edematous wings 0.576
Dsor1 Downstream of raf1 0.575
Su(dx) Suppressor of deltex 0.563
H Hairless 0.563
Ubqn Ubiquilin 0.556
NFAT NFAT homolog 0.553
cv-c crossveinless c 0.553
ebi CG4063 gene product from transcript CG4063-RA 0.551
fj four-jointed 0.542
Fas2 Fasciclin 2 0.540
Socs36E Suppressor of cytokine signaling at 36E 0.540
tok tolkin 0.537
Mef2 Myocyte enhancer factor 2 0.537
wts warts 0.534
sfl sulfateless 0.534
E(spl) Enhancer of split 0.529
Hsc70-4 Heat shock protein cognate 4 0.521
sbb scribbler 0.517
gig gigas 0.511
myoglianin CG1838 gene product from transcript CG1838-RD 0.495
Kr-h1 Kruppel homolog 1 0.491
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Homo sapiens
Name Description Probability Func Analog Organism
EGFR epidermal growth factor receptor 1.000
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 1.000
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 1.000
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.000
GRB2 growth factor receptor-bound protein 2 1.000
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 1.000
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 1.000
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 1.000
PTPN1 protein tyrosine phosphatase, non-receptor type 1 1.000
FYN FYN oncogene related to SRC, FGR, YES 1.000
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.000
JUN jun proto-oncogene 1.000
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.000
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.000
PLCG1 phospholipase C, gamma 1 1.000
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 1.000
BCAR1 breast cancer anti-estrogen resistance 1 1.000
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 1.000
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 1.000
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.000
SMAD3 SMAD family member 3 1.000
MET met proto-oncogene (hepatocyte growth factor receptor) 1.000
LCK lymphocyte-specific protein tyrosine kinase 1.000
GRB7 growth factor receptor-bound protein 7 0.999
FOS FBJ murine osteosarcoma viral oncogene homolog 0.999
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.999
SMAD4 SMAD family member 4 0.999
PTK2 PTK2 protein tyrosine kinase 2 0.999
CREBBP CREB binding protein 0.999
ESR1 estrogen receptor 1 0.998
CAV1 caveolin 1, caveolae protein, 22kDa 0.998
FN1 fibronectin 1 0.998
SMAD2 SMAD family member 2 0.998
DUSP1 dual specificity phosphatase 1 0.997
MAPK8 mitogen-activated protein kinase 8 0.997
SMAD1 SMAD family member 1 0.997
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.996
IRS1 insulin receptor substrate 1 0.996
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.996
SMAD7 SMAD family member 7 0.996
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.994
SKIL SKI-like oncogene 0.993
FGFR2 fibroblast growth factor receptor 2 0.993
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.992
MAPK1 mitogen-activated protein kinase 1 0.992
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.992
GRB10 growth factor receptor-bound protein 10 0.989
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.989
INSR insulin receptor 0.987
TGFB1 transforming growth factor, beta 1 0.986
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.985
MAPK14 mitogen-activated protein kinase 14 0.985
APP amyloid beta (A4) precursor protein 0.985
SYK spleen tyrosine kinase 0.984
FGF1 fibroblast growth factor 1 (acidic) 0.984
FHL2 four and a half LIM domains 2 0.982
NCK1 NCK adaptor protein 1 0.982
SOCS1 suppressor of cytokine signaling 1 0.981
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.979
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 0.978
SP1 Sp1 transcription factor 0.977
PDCD6IP programmed cell death 6 interacting protein 0.976
MAP2K4 mitogen-activated protein kinase kinase 4 0.974
SH3KBP1 SH3-domain kinase binding protein 1 0.972
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.971
AR androgen receptor 0.969
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.968
GSK3B glycogen synthase kinase 3 beta 0.966
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.959
ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.956
GHR growth hormone receptor 0.955
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.955
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.952
TP53 tumor protein p53 0.949
DLG1 discs, large homolog 1 (Drosophila) 0.947
IGF1R insulin-like growth factor 1 receptor 0.946
NCK2 NCK adaptor protein 2 0.942
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.942
TGFBR1 transforming growth factor, beta receptor 1 0.941
SOCS3 suppressor of cytokine signaling 3 0.941
SIRT1 sirtuin 1 0.940
FGFR1 fibroblast growth factor receptor 1 0.939
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.937
PRKCA protein kinase C, alpha 0.935
ATF2 activating transcription factor 2 0.933
VAV1 vav 1 guanine nucleotide exchange factor 0.928
FLNA filamin A, alpha 0.924
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.922
PTK2B PTK2B protein tyrosine kinase 2 beta 0.921
NCOA1 nuclear receptor coactivator 1 0.919
APC adenomatous polyposis coli 0.912
GAB1 GRB2-associated binding protein 1 0.910
ATF3 activating transcription factor 3 0.909
EP300 E1A binding protein p300 0.900
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.898
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.893
COL6A2 collagen, type VI, alpha 2 0.891
ELN elastin 0.887
THBS1 thrombospondin 1 0.882
LTBP2 latent transforming growth factor beta binding protein 2 0.882
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Mus musculus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism