The network for 'otolith morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

otolith morphogenesis

The process in which the anatomical structures of an otolith are generated and organized.

Danio rerio
Name Description Probability Func Analog Organism
dla deltaA 0.832
notch1a notch homolog 1a 0.569
dld deltaD 0.554
pax2a paired box gene 2a 0.553
hnf1ba HNF1 homeobox Ba 0.547
dlc deltaC 0.449
mib mind bomb 0.437
eya1 eyes absent homolog 1 0.391
gli2a GLI-Kruppel family member GLI2a 0.339
fgf3 fibroblast growth factor 3 0.316
isl1 islet1 0.247
osr2 odd-skipped related 2 (Drosophila) 0.234
jag1b jagged 1b 0.231
neurog1 neurogenin 1 0.219
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.181
foxi1 forkhead box I1 0.169
slc12a2 solute carrier family 12 (potassium/chloride transporters), member 2 0.160
notch3 notch homolog 3 0.153
cdh2 cadherin 2, neuronal 0.126
esr2b estrogen receptor 2b 0.103
ptch2 patched 2 0.099
cxcr4b chemokine (C-X-C motif), receptor 4b 0.087
sim1a single-minded homolog 1a (Drosophila) 0.086
esr1 estrogen receptor 1 0.085
pax8 paired box gene 8 0.081
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.078
kitb kit receptor b 0.066
cdh23 cadherin-like 23 0.064
ascl1a achaete-scute complex-like 1a (Drosophila) 0.064
shha sonic hedgehog a 0.060
lhx2b LIM homeobox 2b 0.056
dlb deltaB 0.054
gbx1 gastrulation brain homeobox 1 0.053
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.053
nkx2.1a NK2 homeobox 1a 0.052
itgav integrin, alpha V 0.051
prox1 prospero-related homeobox gene 1 0.050
fgf8a fibroblast growth factor 8 a 0.048
insm1b insulinoma-associated 1b 0.046
hhip hedgehog interacting protein 0.045
pax6b paired box gene 6b 0.045
otpb orthopedia homolog b 0.040
six2a sine oculis-related homeobox 2a 0.038
ndr2 nodal-related 2 0.038
tbx2b T-box 2b 0.036
tbx1 T-box 1 0.036
barhl2 BarH-like 2 0.036
tbx24 T-box 24 0.034
mmp2 matrix metalloproteinase 2 0.034
irx7 iroquois homeobox protein 7 0.032
eve1 even-skipped-like1 0.030
lrrc6 leucine rich repeat containing 6 0.030
foxj1b forkhead box J1b 0.029
chd chordin 0.029
etv2 ets variant gene 2 0.029
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.028
wnt11 wingless-type MMTV integration site family, member 11 0.028
fzd8a frizzled homolog 8a 0.027
six4b sine oculis homeobox homolog 4b 0.027
wt1a wilms tumor 1a 0.027
rfx2 regulatory factor X, 2 (influences HLA class II expression) 0.027
robo3 roundabout homolog 3 0.027
wnt1 wingless-type MMTV integration site family, member 1 0.026
otpa orthopedia homolog a 0.026
dbx1a developing brain homeobox 1a 0.026
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.026
lmx1b.2 LIM homeobox transcription factor 1, beta 2 0.026
pitx3 paired-like homeodomain transcription factor 3 0.025
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.025
sox10 SRY-box containing gene 10 0.024
traf4a tnf receptor-associated factor 4a 0.024
msgn1 mesogenin 1 0.024
her15.1 hairy and enhancer of split-related 15.1 0.024
nr5a2 nuclear receptor subfamily 5, group A, member 2 0.023
bmp4 bone morphogenetic protein 4 0.021
gata3 GATA-binding protein 3 0.021
gdnf glial cell derived neurotrophic factor 0.021
tll1 tolloid-like 1 0.021
evx1 even-skipped homeobox 1 0.020
lef1 lymphocyte enhancer binding factor 1 0.020
tbx20 T-box 20 0.020
lrrc50 leucine rich repeat containing 50 0.020
gyltl1b glycosyltransferase-like 1b 0.020
vangl2 vang-like 2 (van gogh, Drosophila) 0.019
her12 hairy-related 12 0.019
flh floating head 0.019
adcyap1r1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 0.019
otx5 orthodenticle homolog 5 0.019
hnf4a hepatocyte nuclear factor 4, alpha 0.018
oxtl oxytocin-like 0.018
unc45a unc-45 homolog A (C. elegans) 0.018
osr1 odd-skipped related 1 (Drosophila) 0.017
birc2 baculoviral IAP repeat-containing 2 0.017
dlx2b distal-less homeobox gene 2b 0.017
rx3 retinal homeobox gene 3 0.017
irx3b iroquois homeobox protein 3b 0.017
sox21b SRY-box containing gene 21 b 0.017
dio2 deiodinase, iodothyronine, type II 0.016
si:dkey-228g21.4 si:dkey-228g21.4 0.016
cdx4 caudal type homeo box transcription factor 4 0.015
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Foxc1 forkhead box C1 0.997
Tgfb2 transforming growth factor, beta 2 0.996
Bmp4 bone morphogenetic protein 4 0.996
Foxc2 forkhead box C2 0.991
Tbx1 T-box 1 0.990
Fgf8 fibroblast growth factor 8 0.989
Shh sonic hedgehog 0.984
Fgfr1 fibroblast growth factor receptor 1 0.984
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.967
Pitx2 paired-like homeodomain transcription factor 2 0.963
Fgfr2 fibroblast growth factor receptor 2 0.961
Pax2 paired box gene 2 0.950
Eya1 eyes absent 1 homolog (Drosophila) 0.943
Bmp7 bone morphogenetic protein 7 0.911
Otx2 orthodenticle homolog 2 (Drosophila) 0.878
Tcfap2a transcription factor AP-2, alpha 0.871
Gli3 GLI-Kruppel family member GLI3 0.845
Chd7 chromodomain helicase DNA binding protein 7 0.832
Pax3 paired box gene 3 0.823
Hand2 heart and neural crest derivatives expressed transcript 2 0.823
Rarg retinoic acid receptor, gamma 0.811
Hoxa1 homeobox A1 0.779
Sox9 SRY-box containing gene 9 0.777
Zeb1 zinc finger E-box binding homeobox 1 0.762
Gli2 GLI-Kruppel family member GLI2 0.708
Ednra endothelin receptor type A 0.698
Chrd chordin 0.681
Rarb retinoic acid receptor, beta 0.681
Prrx1 paired related homeobox 1 0.641
Msx1 homeobox, msh-like 1 0.631
Vangl2 vang-like 2 (van gogh, Drosophila) 0.578
Foxg1 forkhead box G1 0.572
Gbx2 gastrulation brain homeobox 2 0.555
Dlx5 distal-less homeobox 5 0.444
Vegfa vascular endothelial growth factor A 0.436
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.432
Otx1 orthodenticle homolog 1 (Drosophila) 0.409
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.402
Efnb2 ephrin B2 0.395
Ece1 endothelin converting enzyme 1 0.371
Acvr1 activin A receptor, type 1 0.352
Hand1 heart and neural crest derivatives expressed transcript 1 0.320
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.307
Hes1 hairy and enhancer of split 1 (Drosophila) 0.302
Gsc goosecoid homeobox 0.225
Tgfbr2 transforming growth factor, beta receptor II 0.195
Gata4 GATA binding protein 4 0.183
Isl1 ISL1 transcription factor, LIM/homeodomain 0.183
Rxra retinoid X receptor alpha 0.160
Prrx2 paired related homeobox 2 0.150
Sox2 SRY-box containing gene 2 0.134
Fgfr3 fibroblast growth factor receptor 3 0.128
Smo smoothened homolog (Drosophila) 0.104
Mn1 meningioma 1 0.098
Emx2 empty spiracles homolog 2 (Drosophila) 0.091
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.089
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.079
Msx2 homeobox, msh-like 2 0.077
Hoxa3 homeobox A3 0.076
Fgf10 fibroblast growth factor 10 0.075
Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.074
Ntf3 neurotrophin 3 0.072
Bmp2 bone morphogenetic protein 2 0.071
Alx1 ALX homeobox 1 0.069
Jag1 jagged 1 0.068
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.068
Rara retinoic acid receptor, alpha 0.068
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.067
Lrp6 low density lipoprotein receptor-related protein 6 0.065
Notch1 Notch gene homolog 1 (Drosophila) 0.063
Gja1 gap junction protein, alpha 1 0.061
Pax6 paired box gene 6 0.059
Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 0.059
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.057
Bicc1 bicaudal C homolog 1 (Drosophila) 0.057
Ptch1 patched homolog 1 0.052
Bmper BMP-binding endothelial regulator 0.052
Pkd1 polycystic kidney disease 1 homolog 0.052
Psen1 presenilin 1 0.047
Mesp1 mesoderm posterior 1 0.046
Nog noggin 0.045
Fgfrl1 fibroblast growth factor receptor-like 1 0.044
Foxi3 forkhead box I3 0.043
Sox4 SRY-box containing gene 4 0.038
Cno cappuccino 0.038
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.038
Hoxa2 homeobox A2 0.037
En1 engrailed 1 0.033
Sox11 SRY-box containing gene 11 0.032
Gas1 growth arrest specific 1 0.031
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.031
Gata6 GATA binding protein 6 0.031
Tbx10 T-box 10 0.028
Col4a1 collagen, type IV, alpha 1 0.027
Pbx1 pre B-cell leukemia transcription factor 1 0.027
Rdh10 retinol dehydrogenase 10 (all-trans) 0.027
Hmx3 H6 homeobox 3 0.026
Tcof1 Treacher Collins Franceschetti syndrome 1, homolog 0.024
Dll1 delta-like 1 (Drosophila) 0.024
Pds5b PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) 0.023
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism