The network for 'regulation of skeletal muscle tissue development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of skeletal muscle tissue development

Any process that modulates the frequency, rate or extent of skeletal muscle tissue development.

Name Description Probability Func Analog Organism
cdh2 cadherin 2, neuronal 0.973
bmp2b bone morphogenetic protein 2b 0.880
tbx1 T-box 1 0.805
sox9a SRY-box containing gene 9a 0.764
foxi1 forkhead box I1 0.632
myod1 myogenic differentiation 1 0.500
pcdh8 protocadherin 8 0.500
jhdm1da jumonji C domain containing histone demethylase 1 homolog Da (S. cerevisiae) 0.355
tbx20 T-box 20 0.341
bmp4 bone morphogenetic protein 4 0.295
fgf10a fibroblast growth factor 10a 0.291
bambia BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a 0.286
notch1b notch homolog 1b 0.273
wnt5b wingless-type MMTV integration site family, member 5b 0.266
crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.254
cry3 cryptochrome 3 0.252
skia nuclear oncoprotein skia 0.238
mef2d myocyte enhancer factor 2d 0.227
tnfrsfa tumor necrosis factor receptor superfamily, member a 0.221
hmx2 H6 family homeobox 2 0.214
chrna1 cholinergic receptor, nicotinic, alpha polypeptide 1 0.204
dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.202
efnb2a ephrin B2a 0.194
dkk1b dickkopf 1b 0.178
mef2ca myocyte enhancer factor 2ca 0.174
rarga retinoic acid receptor gamma a 0.169
her6 hairy-related 6 0.167
xirp1 xin actin-binding repeat containing 1 0.164
zgc:172136 zgc:172136 0.162
klf4a Kruppel-like transcription factor 4a 0.162
smo smoothened homolog (Drosophila) 0.158
mef2a myocyte enhancer factor 2a 0.154
vasp vasodilator-stimulated phosphoprotein 0.150
aldh1a3 aldehyde dehydrogenase 1 family, member A3 0.149
fgf3 fibroblast growth factor 3 0.142
cry1a cryptochrome 1a 0.138
gpr126 G protein-coupled receptor 126 0.136
znf503 zinc finger protein 503 0.133
lef1 lymphocyte enhancer binding factor 1 0.133
tgfb3 transforming growth factor, beta 3 0.130
grifin galectin related inter-fiber protein 0.129
myf5 myogenic factor 5 0.129
id3 inhibitor of DNA binding 3 0.121
brd4 bromodomain containing 4 0.121
fzd8a frizzled homolog 8a 0.118
igfbp3 insulin-like growth factor binding protein 3 0.113
atp1b2b ATPase, Na+/K+ transporting, beta 2b polypeptide 0.112
jam3b junctional adhesion molecule 3b 0.109
tnnt2a troponin T2a, cardiac 0.108
tbx18 T-box 18 0.107
chd chordin 0.106
cxcr4a chemokine (C-X-C motif) receptor 4a 0.106
unc45b unc-45 homolog B (C. elegans) 0.105
pth1a parathyroid hormone 1a 0.104
slit3 slit (Drosophila) homolog 3 0.104
zgc:77714 zgc:77714 0.104
smyd1b SET and MYND domain containing 1b 0.104
tp53bp2 tumor protein p53 binding protein, 2 0.103
col14a1 collagen, type XIV, alpha 1 0.103
timp2a tissue inhibitor of metalloproteinase 2a 0.101
wnt11r wingless-type MMTV integration site family, member 11, related 0.099
ved ventrally expressed dharma/bozozok antagonist 0.096
dacha dachshund a 0.094
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.093
ptrfb polymerase I and transcript release factor b 0.093
antxr1 anthrax toxin receptor 1 0.090
sgcd sarcoglycan, delta (dystrophin-associated glycoprotein) 0.090
six4a sine oculis homeobox homolog 4a 0.089
gli2a GLI-Kruppel family member GLI2a 0.086
abcf2 ATP-binding cassette, sub-family F (GCN20), member 2 0.085
wu:fv91b12 wu:fv91b12 0.082
fyna FYN oncogene related to SRC, FGR, YES a 0.082
ntn1a netrin 1a 0.081
nova2 neuro-oncological ventral antigen 2 0.081
hspb12 heat shock protein, alpha-crystallin-related, b12 0.081
hspb1 heat shock protein, alpha-crystallin-related, 1 0.080
dmd dystrophin 0.080
lmna lamin A 0.080
pik3ip1 phosphoinositide-3-kinase interacting protein 1 0.080
zgc:111821 zgc:111821 0.080
tfap2c transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.079
nrg2a neuregulin 2a 0.077
efnb1 ephrin B1 0.076
id2a inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a 0.075
pkd2 polycystic kidney disease 2 0.075
eif4g2a eukaryotic translation initiation factor 4, gamma 2a 0.074
dlx5a distal-less homeobox gene 5a 0.074
tbx2b T-box 2b 0.073
mib mind bomb 0.073
rassf8b Ras association (RalGDS/AF-6) domain family 8b 0.072
nppa natriuretic peptide precursor A 0.071
stm starmaker 0.069
lama4 laminin, alpha 4 0.068
col8a1a collagen, type VIII, alpha 1a 0.068
fgf18a fibroblast growth factor 18a 0.067
arl4cb ADP-ribosylation factor-like 4Cb 0.066
ccnt2b cyclin T2b 0.065
clock3 clock homolog 3 (mouse) 0.065
og9x OG9 homeobox gene 0.065
per3 period homolog 3 (Drosophila) 0.064
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.929
JAG1 jagged 1 0.602
BMPR1A bone morphogenetic protein receptor, type IA 0.311
NOTCH1 notch 1 0.271
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 0.218
FSTL1 follistatin-like 1 0.211
BCL2L1 BCL2-like 1 0.136
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.085
TTN titin 0.076
EP300 E1A binding protein p300 0.061
NOTCH3 notch 3 0.059
JUN jun proto-oncogene 0.059
RB1 retinoblastoma 1 0.057
ESR1 estrogen receptor 1 0.053
SETD8 SET domain containing (lysine methyltransferase) 8 0.048
MEF2C myocyte enhancer factor 2C 0.047
HDAC4 histone deacetylase 4 0.044
MEF2A myocyte enhancer factor 2A 0.041
NEB nebulin 0.040
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.036
MAPK1 mitogen-activated protein kinase 1 0.035
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 0.032
NCOA2 nuclear receptor coactivator 2 0.031
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.031
CNOT8 CCR4-NOT transcription complex, subunit 8 0.029
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.028
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.026
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.025
AR androgen receptor 0.025
IGF2 insulin-like growth factor 2 (somatomedin A) 0.024
FBLN1 fibulin 1 0.023
AHR aryl hydrocarbon receptor 0.022
FUNDC2 FUN14 domain containing 2 0.022
NCOA3 nuclear receptor coactivator 3 0.022
DLL1 delta-like 1 (Drosophila) 0.021
JAG2 jagged 2 0.021
PARVA parvin, alpha 0.020
EGLN1 egl nine homolog 1 (C. elegans) 0.019
TCF4 transcription factor 4 0.019
DUSP1 dual specificity phosphatase 1 0.018
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.018
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.018
CLOCK clock homolog (mouse) 0.017
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.017
ATF4 activating transcription factor 4 (tax-responsive enhancer element B67) 0.016
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.016
SF1 splicing factor 1 0.016
PNRC1 proline-rich nuclear receptor coactivator 1 0.016
SMAD1 SMAD family member 1 0.015
ADAM12 ADAM metallopeptidase domain 12 0.015
HIC1 hypermethylated in cancer 1 0.015
DBP D site of albumin promoter (albumin D-box) binding protein 0.014
CXCL11 chemokine (C-X-C motif) ligand 11 0.014
E2F1 E2F transcription factor 1 0.014
H3F3C H3 histone, family 3C 0.014
ATF3 activating transcription factor 3 0.013
TGFB3 transforming growth factor, beta 3 0.013
ARRDC3 arrestin domain containing 3 0.013
CREBBP CREB binding protein 0.013
HPCAL4 hippocalcin like 4 0.013
INO80B INO80 complex subunit B 0.013
HDAC9 histone deacetylase 9 0.013
KLHL24 kelch-like 24 (Drosophila) 0.013
MAML1 mastermind-like 1 (Drosophila) 0.013
TRIM63 tripartite motif containing 63 0.012
VHL von Hippel-Lindau tumor suppressor 0.012
SMAD7 SMAD family member 7 0.012
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.012
HBP1 HMG-box transcription factor 1 0.011
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.011
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.010
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.010
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism