IMP

Process View

Homo sapiens

22 genes annotated in human

protein import into nucleus translocation

A protein transport process that contributes to protein import into the nucleus, and that results in the vectorial transfer of a cargo-carrier protein complex through the nuclear pore complex from the cytoplasmic side to the nucleoplasmic side of the nuclear envelope.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "protein import into nucleus translocation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "protein import into nucleus translocation" (in gray)

Name	Description	Probability	Func Analog Organism
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.502
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.468
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.399
DTX3L	deltex 3-like (Drosophila)	0.307
AKR1C2	aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)	0.203	Human
HSPA1B	heat shock 70kDa protein 1B	0.176	Yeast
AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	0.176	Human
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.155	Human Mouse
HSPA1A	heat shock 70kDa protein 1A	0.138	Yeast
TRADD	TNFRSF1A-associated via death domain	0.124
BCL3	B-cell CLL/lymphoma 3	0.112
SOCS1	suppressor of cytokine signaling 1	0.071
SMN1	survival of motor neuron 1, telomeric	0.068
BAG3	BCL2-associated athanogene 3	0.068
ENG	endoglin	0.068
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.065
EP300	E1A binding protein p300	0.064
CHUK	conserved helix-loop-helix ubiquitous kinase	0.057
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.055
AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)	0.047
NCF1	neutrophil cytosolic factor 1	0.046
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.043
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.041
NOXA1	NADPH oxidase activator 1	0.040
CDK2	cyclin-dependent kinase 2	0.038
AXL	AXL receptor tyrosine kinase	0.038
MPDZ	multiple PDZ domain protein	0.036
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.033
RXRA	retinoid X receptor, alpha	0.031
TTR	transthyretin	0.031
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.030
PRDX1	peroxiredoxin 1	0.028
MEIS1	Meis homeobox 1	0.028
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.026	Rat
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.025
ESR1	estrogen receptor 1	0.025
NCOR2	nuclear receptor corepressor 2	0.025
SEC61G	Sec61 gamma subunit	0.022
CLOCK	clock homolog (mouse)	0.021
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.020
LAT	linker for activation of T cells	0.020
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.020
MEIS2	Meis homeobox 2	0.020
AQR	aquarius homolog (mouse)	0.020
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.019
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.019
ITGB1BP3	integrin beta 1 binding protein 3	0.018
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.017
PPP5C	protein phosphatase 5, catalytic subunit	0.017
IGF2R	insulin-like growth factor 2 receptor	0.017
PICK1	protein interacting with PRKCA 1	0.016
FAF1	Fas (TNFRSF6) associated factor 1	0.016
MBOAT7	membrane bound O-acyltransferase domain containing 7	0.015
PRLHR	prolactin releasing hormone receptor	0.015
BAG1	BCL2-associated athanogene	0.015
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.015
PROX1	prospero homeobox 1	0.015
RBM4	RNA binding motif protein 4	0.015
INSR	insulin receptor	0.015
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.015
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.014
TSC22D1	TSC22 domain family, member 1	0.014
MAVS	mitochondrial antiviral signaling protein	0.014
ESR2	estrogen receptor 2 (ER beta)	0.013
TMEM173	transmembrane protein 173	0.013
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.013
ACACA	acetyl-CoA carboxylase alpha	0.013
PRKCZ	protein kinase C, zeta	0.013	Human
PKNOX1	PBX/knotted 1 homeobox 1	0.013
STAT5A	signal transducer and activator of transcription 5A	0.013
IGF1R	insulin-like growth factor 1 receptor	0.012
MAPT	microtubule-associated protein tau	0.012
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.012
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.012
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.012
PRKCB	protein kinase C, beta	0.011
IL4R	interleukin 4 receptor	0.011
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.011
SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)	0.011
PARP14	poly (ADP-ribose) polymerase family, member 14	0.011	Human
C19orf6	chromosome 19 open reading frame 6	0.011
PCDH9	protocadherin 9	0.010
BCAP31	B-cell receptor-associated protein 31	0.010
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.010
SH2D1A	SH2 domain containing 1A	0.010
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.010