IMP

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Homo sapiens

2 genes annotated in human

cardiac chamber formation

The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cardiac chamber formation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cardiac chamber formation" (in gray)

Name	Description	Probability	Func Analog Organism
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	1.000
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	1.000	Mouse
TBX5	T-box 5	0.997	Mouse
JAG1	jagged 1	0.990
GATA4	GATA binding protein 4	0.981
RUNX1	runt-related transcription factor 1	0.971
SETD8	SET domain containing (lysine methyltransferase) 8	0.962
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.943
HDAC4	histone deacetylase 4	0.894
NOTCH3	notch 3	0.885
GATA2	GATA binding protein 2	0.804
DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1	0.672
MAML1	mastermind-like 1 (Drosophila)	0.625
XIAP	X-linked inhibitor of apoptosis	0.539
EP300	E1A binding protein p300	0.504
TCF12	transcription factor 12	0.483
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.446
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.352
MYOD1	myogenic differentiation 1	0.344
TCF4	transcription factor 4	0.267
TAL1	T-cell acute lymphocytic leukemia 1	0.260	Human
LMO2	LIM domain only 2 (rhombotin-like 1)	0.207
HIPK2	homeodomain interacting protein kinase 2	0.164
JAG2	jagged 2	0.131
MARCKSL1	MARCKS-like 1	0.119
HDAC9	histone deacetylase 9	0.109
DLL1	delta-like 1 (Drosophila)	0.101
CSNK1E	casein kinase 1, epsilon	0.100
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.099
CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	0.091
MCC	mutated in colorectal cancers	0.088
PDX1	pancreatic and duodenal homeobox 1	0.078
NOTCH2	notch 2	0.073
ATXN1L	ataxin 1-like	0.069
LHX5	LIM homeobox 5	0.061
SPTBN1	spectrin, beta, non-erythrocytic 1	0.059
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.059
KAT2B	K(lysine) acetyltransferase 2B	0.056
POU4F2	POU class 4 homeobox 2	0.051
HAP1	huntingtin-associated protein 1	0.051
TLX2	T-cell leukemia homeobox 2	0.047
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.047
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.045
POU3F2	POU class 3 homeobox 2	0.044
PHOX2A	paired-like homeobox 2a	0.044
SOX1	SRY (sex determining region Y)-box 1	0.043
FAM110A	family with sequence similarity 110, member A	0.041
SIX6	SIX homeobox 6	0.040
HOXB9	homeobox B9	0.039
FOXG1	forkhead box G1	0.037
MYLK2	myosin light chain kinase 2	0.037
HOXD13	homeobox D13	0.036
LMO1	LIM domain only 1 (rhombotin 1)	0.036
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.035
ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	0.035
HES1	hairy and enhancer of split 1, (Drosophila)	0.035
LYL1	lymphoblastic leukemia derived sequence 1	0.035	Human
LRRN2	leucine rich repeat neuronal 2	0.034
C1QL1	complement component 1, q subcomponent-like 1	0.033
EFNB3	ephrin-B3	0.032
PPARG	peroxisome proliferator-activated receptor gamma	0.032
SFRP5	secreted frizzled-related protein 5	0.032
EGFL7	EGF-like-domain, multiple 7	0.031
FGF3	fibroblast growth factor 3	0.031
HAND2	heart and neural crest derivatives expressed 2	0.031	Human Mouse
OTP	orthopedia homeobox	0.030
HIC1	hypermethylated in cancer 1	0.030
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.029
TBX1	T-box 1	0.029
MYT1	myelin transcription factor 1	0.029
SOX18	SRY (sex determining region Y)-box 18	0.029
TAOK1	TAO kinase 1	0.027
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.027
NEUROG1	neurogenin 1	0.027	Human
CREBBP	CREB binding protein	0.026
PYY	peptide YY	0.026
FOXF2	forkhead box F2	0.026
ZIC3	Zic family member 3 (odd-paired homolog, Drosophila)	0.025
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.025
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.025
FAM83D	family with sequence similarity 83, member D	0.025
YY1	YY1 transcription factor	0.025
GATA3	GATA binding protein 3	0.025
MEF2A	myocyte enhancer factor 2A	0.024
EFNB2	ephrin-B2	0.023
POU4F3	POU class 4 homeobox 3	0.023
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.023
GATA5	GATA binding protein 5	0.022
TBX2	T-box 2	0.022
BHLHE23	basic helix-loop-helix family, member e23	0.022
OCLN	occludin	0.021
GABRB1	gamma-aminobutyric acid (GABA) A receptor, beta 1	0.021
NHLH2	nescient helix loop helix 2	0.021	Human
MNX1	motor neuron and pancreas homeobox 1	0.021
ALX4	ALX homeobox 4	0.021
ALX3	ALX homeobox 3	0.021
ADCYAP1	adenylate cyclase activating polypeptide 1 (pituitary)	0.021
NEUROD2	neurogenic differentiation 2	0.020	Human
BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	0.020
CELF4	CUGBP, Elav-like family member 4	0.020
PCDH17	protocadherin 17	0.020
HOXA3	homeobox A3	0.020
SOX11	SRY (sex determining region Y)-box 11	0.020	Mouse
TRIM67	tripartite motif containing 67	0.020
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.020
GSC2	goosecoid homeobox 2	0.019
TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	0.019
DIABLO	diablo, IAP-binding mitochondrial protein	0.019
CDX2	caudal type homeobox 2	0.019
COL11A1	collagen, type XI, alpha 1	0.019
PITX2	paired-like homeodomain 2	0.018
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.018
ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.018
NEUROG3	neurogenin 3	0.018	Human
COL2A1	collagen, type II, alpha 1	0.018
EPAS1	endothelial PAS domain protein 1	0.018
TLX1	T-cell leukemia homeobox 1	0.018
TBR1	T-box, brain, 1	0.018
FOXB1	forkhead box B1	0.018
ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	0.018
SLC30A3	solute carrier family 30 (zinc transporter), member 3	0.018
FEV	FEV (ETS oncogene family)	0.018
NKX3-2	NK3 homeobox 2	0.018
HOXD11	homeobox D11	0.018
NRXN1	neurexin 1	0.018
MAGED1	melanoma antigen family D, 1	0.018
HOXA5	homeobox A5	0.017
NOVA2	neuro-oncological ventral antigen 2	0.017
HOXD12	homeobox D12	0.017
PRDM13	PR domain containing 13	0.017
CBFB	core-binding factor, beta subunit	0.017
DLL4	delta-like 4 (Drosophila)	0.017
HMGA2	high mobility group AT-hook 2	0.017
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.017
HBQ1	hemoglobin, theta 1	0.017
PAX2	paired box 2	0.017
POU4F1	POU class 4 homeobox 1	0.017
POU3F3	POU class 3 homeobox 3	0.017
HOXA4	homeobox A4	0.016
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.016
DPYSL5	dihydropyrimidinase-like 5	0.016
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.016
FOXE3	forkhead box E3	0.016
ANK1	ankyrin 1, erythrocytic	0.016
POU3F4	POU class 3 homeobox 4	0.016
GSX2	GS homeobox 2	0.016
BARHL1	BarH-like homeobox 1	0.016
NEUROG2	neurogenin 2	0.016	Human
NPAS1	neuronal PAS domain protein 1	0.016
SART1	squamous cell carcinoma antigen recognized by T cells	0.016
SHOX2	short stature homeobox 2	0.016
WNT10A	wingless-type MMTV integration site family, member 10A	0.016
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.016
HOXD9	homeobox D9	0.016
DBN1	drebrin 1	0.016
ARX	aristaless related homeobox	0.015
NEUROD1	neurogenic differentiation 1	0.015	Human
HOXC11	homeobox C11	0.015
WT1	Wilms tumor 1	0.015
ELAVL4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)	0.015
SCGN	secretagogin, EF-hand calcium binding protein	0.015
TP73	tumor protein p73	0.015
DLL3	delta-like 3 (Drosophila)	0.015
CELF2	CUGBP, Elav-like family member 2	0.015
FEZF2	FEZ family zinc finger 2	0.015
VAX1	ventral anterior homeobox 1	0.015
DHH	desert hedgehog	0.015
C5orf13	chromosome 5 open reading frame 13	0.015
SCARF2	scavenger receptor class F, member 2	0.014
SNW1	SNW domain containing 1	0.014
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.014
SLITRK3	SLIT and NTRK-like family, member 3	0.014
NGB	neuroglobin	0.014
HOXD3	homeobox D3	0.014
RAX	retina and anterior neural fold homeobox	0.014
HES2	hairy and enhancer of split 2 (Drosophila)	0.014
INSM1	insulinoma-associated 1	0.014
CDK6	cyclin-dependent kinase 6	0.014
KDM5B	lysine (K)-specific demethylase 5B	0.014
RARA	retinoic acid receptor, alpha	0.014
RAP1GAP	RAP1 GTPase activating protein	0.014
GFI1B	growth factor independent 1B transcription repressor	0.014
ECEL1	endothelin converting enzyme-like 1	0.014
CELF3	CUGBP, Elav-like family member 3	0.014
CACNG3	calcium channel, voltage-dependent, gamma subunit 3	0.014
SOX9	SRY (sex determining region Y)-box 9	0.014
ELAVL3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.014
VSX1	visual system homeobox 1	0.014
BHLHE22	basic helix-loop-helix family, member e22	0.014
HOXB7	homeobox B7	0.014
LBX1	ladybird homeobox 1	0.013
NKX2-2	NK2 homeobox 2	0.013
SOX21	SRY (sex determining region Y)-box 21	0.013
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.013
GCM2	glial cells missing homolog 2 (Drosophila)	0.013
FOXL1	forkhead box L1	0.013
TBXA2R	thromboxane A2 receptor	0.013
ZFPM1	zinc finger protein, multitype 1	0.013
CYP2A13	cytochrome P450, family 2, subfamily A, polypeptide 13	0.013
FAM110C	family with sequence similarity 110, member C	0.013
SCRT2	scratch homolog 2, zinc finger protein (Drosophila)	0.013
AMN	amnionless homolog (mouse)	0.013
HOXB5	homeobox B5	0.013
STMN2	stathmin-like 2	0.013
SPTBN4	spectrin, beta, non-erythrocytic 4	0.013
MDK	midkine (neurite growth-promoting factor 2)	0.013
SSTR2	somatostatin receptor 2	0.013
HOXD4	homeobox D4	0.013
TNNI1	troponin I type 1 (skeletal, slow)	0.013
PKNOX2	PBX/knotted 1 homeobox 2	0.013
NEURL	neuralized homolog (Drosophila)	0.013
CYP26C1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.013
WNT9B	wingless-type MMTV integration site family, member 9B	0.013
ELF4	E74-like factor 4 (ets domain transcription factor)	0.013
FAM123A	family with sequence similarity 123A	0.013
EVX1	even-skipped homeobox 1	0.013
KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.012
KCNA5	potassium voltage-gated channel, shaker-related subfamily, member 5	0.012
PTF1A	pancreas specific transcription factor, 1a	0.012	Human
PRLHR	prolactin releasing hormone receptor	0.012
ASCL1	achaete-scute complex homolog 1 (Drosophila)	0.012
GPR25	G protein-coupled receptor 25	0.012
PAX4	paired box 4	0.012
PAX7	paired box 7	0.012
HOXD1	homeobox D1	0.012
CD200	CD200 molecule	0.012
TGIF2	TGFB-induced factor homeobox 2	0.012
PCDH8	protocadherin 8	0.012
ICAM5	intercellular adhesion molecule 5, telencephalin	0.012
HOXA11	homeobox A11	0.012
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.012
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.012
OLIG3	oligodendrocyte transcription factor 3	0.012
HOXB13	homeobox B13	0.012
CD164L2	CD164 sialomucin-like 2	0.012
SLC17A6	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6	0.012
SLC16A11	solute carrier family 16, member 11 (monocarboxylic acid transporter 11)	0.012
ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	0.012
WNT3A	wingless-type MMTV integration site family, member 3A	0.012
PTPRR	protein tyrosine phosphatase, receptor type, R	0.012
PDK1	pyruvate dehydrogenase kinase, isozyme 1	0.012
MPL	myeloproliferative leukemia virus oncogene	0.012
TWIST2	twist homolog 2 (Drosophila)	0.012
BRSK2	BR serine/threonine kinase 2	0.012
ST18	suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)	0.011
ICAM4	intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)	0.011
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.011
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.011
HES5	hairy and enhancer of split 5 (Drosophila)	0.011
SST	somatostatin	0.011
CIR1	corepressor interacting with RBPJ, 1	0.011
S1PR4	sphingosine-1-phosphate receptor 4	0.011
SNAI1	snail homolog 1 (Drosophila)	0.011
CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.011
FABP7	fatty acid binding protein 7, brain	0.011
ZMYND8	zinc finger, MYND-type containing 8	0.011
JMY	junction mediating and regulatory protein, p53 cofactor	0.011
ZNF532	zinc finger protein 532	0.011
PTH2	parathyroid hormone 2	0.011
GAL	galanin prepropeptide	0.011
HOXC12	homeobox C12	0.011
CAMTA2	calmodulin binding transcription activator 2	0.011
SLC30A2	solute carrier family 30 (zinc transporter), member 2	0.011
RORB	RAR-related orphan receptor B	0.011
WNT6	wingless-type MMTV integration site family, member 6	0.011
HAND1	heart and neural crest derivatives expressed 1	0.011
FOXH1	forkhead box H1	0.011
HES6	hairy and enhancer of split 6 (Drosophila)	0.011
GBX2	gastrulation brain homeobox 2	0.011
MYL4	myosin, light chain 4, alkali; atrial, embryonic	0.011
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.011
GABRB3	gamma-aminobutyric acid (GABA) A receptor, beta 3	0.011
GGN	gametogenetin	0.011
LTK	leukocyte receptor tyrosine kinase	0.011
MMD2	monocyte to macrophage differentiation-associated 2	0.011
BRD3	bromodomain containing 3	0.011
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.011
PAX6	paired box 6	0.011
PPP1R12C	protein phosphatase 1, regulatory (inhibitor) subunit 12C	0.011
KCNC2	potassium voltage-gated channel, Shaw-related subfamily, member 2	0.011
FOXD3	forkhead box D3	0.011
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.011
KCNC1	potassium voltage-gated channel, Shaw-related subfamily, member 1	0.011
CAMK2N2	calcium/calmodulin-dependent protein kinase II inhibitor 2	0.011
NFE2	nuclear factor (erythroid-derived 2), 45kDa	0.011
HBZ	hemoglobin, zeta	0.011
TCF15	transcription factor 15 (basic helix-loop-helix)	0.011	Human
CNOT4	CCR4-NOT transcription complex, subunit 4	0.011
TLX3	T-cell leukemia homeobox 3	0.011
PAX5	paired box 5	0.011
HOXA13	homeobox A13	0.011
FOXN4	forkhead box N4	0.011
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.011
NKD1	naked cuticle homolog 1 (Drosophila)	0.010
MESP1	mesoderm posterior 1 homolog (mouse)	0.010
MAPK4	mitogen-activated protein kinase 4	0.010
PRDM8	PR domain containing 8	0.010
CBLN1	cerebellin 1 precursor	0.010
HMX2	H6 family homeobox 2	0.010
DLK1	delta-like 1 homolog (Drosophila)	0.010
ADD2	adducin 2 (beta)	0.010
NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.010
MATN4	matrilin 4	0.010
EN1	engrailed homeobox 1	0.010
PCDHA2	protocadherin alpha 2	0.010
PHOX2B	paired-like homeobox 2b	0.010
NNAT	neuronatin	0.010
PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase	0.010
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.010
BARHL2	BarH-like homeobox 2	0.010
TEAD2	TEA domain family member 2	0.010
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.010
SIX2	SIX homeobox 2	0.010
KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.010
CDH15	cadherin 15, type 1, M-cadherin (myotubule)	0.010
NKX6-3	NK6 homeobox 3	0.010
KCNS1	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1	0.010
TBX20	T-box 20	0.010
TBXAS1	thromboxane A synthase 1 (platelet)	0.010
INSM2	insulinoma-associated 2	0.010
SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5	0.010
HOXC8	homeobox C8	0.010
CHRND	cholinergic receptor, nicotinic, delta	0.010
MOS	v-mos Moloney murine sarcoma viral oncogene homolog	0.010
DCC	deleted in colorectal carcinoma	0.010
VAX2	ventral anterior homeobox 2	0.010
FOXF1	forkhead box F1	0.010
TMSB15A	thymosin beta 15a	0.010
GABRA4	gamma-aminobutyric acid (GABA) A receptor, alpha 4	0.010
CACNA1E	calcium channel, voltage-dependent, R type, alpha 1E subunit	0.010
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	0.010