IMP

Process View

Homo sapiens

20 genes annotated in human

cardiac ventricle morphogenesis

The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cardiac ventricle morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cardiac ventricle morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
TNNC1	troponin C type 1 (slow)	1.000
TNNI1	troponin I type 1 (skeletal, slow)	0.998	Human Mouse
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.983
TPM1	tropomyosin 1 (alpha)	0.964
NOTCH1	notch 1	0.860	Mouse
EP300	E1A binding protein p300	0.833
NOTCH3	notch 3	0.827
SMYD1	SET and MYND domain containing 1	0.818
TBX5	T-box 5	0.796	Mouse
TNNT2	troponin T type 2 (cardiac)	0.754
COX6A2	cytochrome c oxidase subunit VIa polypeptide 2	0.708
NCOA1	nuclear receptor coactivator 1	0.699
MED25	mediator complex subunit 25	0.694
TNNI2	troponin I type 2 (skeletal, fast)	0.647	Human
TPM2	tropomyosin 2 (beta)	0.607	Human
CKM	creatine kinase, muscle	0.581
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.549
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.530
HAP1	huntingtin-associated protein 1	0.509
ACTA1	actin, alpha 1, skeletal muscle	0.507
MYL1	myosin, light chain 1, alkali; skeletal, fast	0.496	Human
MYH7	myosin, heavy chain 7, cardiac muscle, beta	0.469
ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.423
SMAD9	SMAD family member 9	0.392
SFN	stratifin	0.384
MYH1	myosin, heavy chain 1, skeletal muscle, adult	0.355	Human
DSP	desmoplakin	0.350	Mouse
ESR1	estrogen receptor 1	0.324
MYL2	myosin, light chain 2, regulatory, cardiac, slow	0.322
LDB3	LIM domain binding 3	0.321
TNNT1	troponin T type 1 (skeletal, slow)	0.310	Human
ACVR1B	activin A receptor, type IB	0.305
TNNT3	troponin T type 3 (skeletal, fast)	0.302	Human
FGF10	fibroblast growth factor 10	0.292
MYOD1	myogenic differentiation 1	0.284
TRIM63	tripartite motif containing 63	0.265
GATA4	GATA binding protein 4	0.257	Zebrafish Mouse
MYH9	myosin, heavy chain 9, non-muscle	0.238
KRT14	keratin 14	0.235
MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle	0.234	Human
MYH2	myosin, heavy chain 2, skeletal muscle, adult	0.227	Human
MYL4	myosin, light chain 4, alkali; atrial, embryonic	0.223	Human
PDLIM7	PDZ and LIM domain 7 (enigma)	0.208
JUP	junction plakoglobin	0.193
TNNC2	troponin C type 2 (fast)	0.188	Human
DES	desmin	0.187
GATA2	GATA binding protein 2	0.178
FGF1	fibroblast growth factor 1 (acidic)	0.170
MYBPC2	myosin binding protein C, fast type	0.167
VCP	valosin containing protein	0.161
HNF4A	hepatocyte nuclear factor 4, alpha	0.160
JAG1	jagged 1	0.150	Mouse
ESR2	estrogen receptor 2 (ER beta)	0.148
GSK3B	glycogen synthase kinase 3 beta	0.130
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.127
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.120	Mouse
SMAD3	SMAD family member 3	0.119
CXXC5	CXXC finger protein 5	0.116
SGCA	sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)	0.115
RARA	retinoic acid receptor, alpha	0.110
CTBP2	C-terminal binding protein 2	0.108
ACTN3	actinin, alpha 3	0.103
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.098
RB1	retinoblastoma 1	0.097
KAT2B	K(lysine) acetyltransferase 2B	0.096
MYL3	myosin, light chain 3, alkali; ventricular, skeletal, slow	0.092
KRT8	keratin 8	0.091
MYH6	myosin, heavy chain 6, cardiac muscle, alpha	0.091
TAL1	T-cell acute lymphocytic leukemia 1	0.089	Human
MYBPC1	myosin binding protein C, slow type	0.087
ACTC1	actin, alpha, cardiac muscle 1	0.082
TGFBR1	transforming growth factor, beta receptor 1	0.080
PSEN1	presenilin 1	0.079
PKP2	plakophilin 2	0.074
ARNT	aryl hydrocarbon receptor nuclear translocator	0.071
TNS4	tensin 4	0.070
MYL12B	myosin, light chain 12B, regulatory	0.068	Human
EPAS1	endothelial PAS domain protein 1	0.068
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.064
PAX8	paired box 8	0.062
AKAP12	A kinase (PRKA) anchor protein 12	0.061
MAML1	mastermind-like 1 (Drosophila)	0.060
HIPK2	homeodomain interacting protein kinase 2	0.060
RIPK3	receptor-interacting serine-threonine kinase 3	0.059
SOX11	SRY (sex determining region Y)-box 11	0.058	Mouse
CORO1C	coronin, actin binding protein, 1C	0.056
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.053
ACTN2	actinin, alpha 2	0.052
SOX7	SRY (sex determining region Y)-box 7	0.048
CCK	cholecystokinin	0.046
PDE4DIP	phosphodiesterase 4D interacting protein	0.046
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.046
SMAD2	SMAD family member 2	0.044
FLNA	filamin A, alpha	0.043
MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric	0.043	Human
NSFL1C	NSFL1 (p97) cofactor (p47)	0.041
NOTCH2	notch 2	0.040
PML	promyelocytic leukemia	0.039
DSG2	desmoglein 2	0.038
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.038
MARCKSL1	MARCKS-like 1	0.037
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.036
SMAD6	SMAD family member 6	0.036
APOBEC2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2	0.036
FOXG1	forkhead box G1	0.036
SLN	sarcolipin	0.035
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.035
RUNX1	runt-related transcription factor 1	0.035
MYOG	myogenin (myogenic factor 4)	0.033
HAND1	heart and neural crest derivatives expressed 1	0.033
FRMD5	FERM domain containing 5	0.032
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.032
AKAP6	A kinase (PRKA) anchor protein 6	0.032
MYLK	myosin light chain kinase	0.032
CASQ2	calsequestrin 2 (cardiac muscle)	0.032
HAND2	heart and neural crest derivatives expressed 2	0.032	Human Mouse
CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.031
MYL7	myosin, light chain 7, regulatory	0.029	Human
PHOX2A	paired-like homeobox 2a	0.029
TPM4	tropomyosin 4	0.029	Human
MYBPH	myosin binding protein H	0.029
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.028
CNN1	calponin 1, basic, smooth muscle	0.028
SRPK3	SRSF protein kinase 3	0.027
MB	myoglobin	0.027
DLL1	delta-like 1 (Drosophila)	0.027
CREBBP	CREB binding protein	0.027
ATXN3	ataxin 3	0.027
MARK3	MAP/microtubule affinity-regulating kinase 3	0.027
ROBO2	roundabout, axon guidance receptor, homolog 2 (Drosophila)	0.026
AXIN1	axin 1	0.026
PGAM2	phosphoglycerate mutase 2 (muscle)	0.026
ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa	0.026
SIRT1	sirtuin 1	0.026
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.025	Mouse
SMPX	small muscle protein, X-linked	0.025
LAPTM5	lysosomal protein transmembrane 5	0.025
DBN1	drebrin 1	0.025
CDH15	cadherin 15, type 1, M-cadherin (myotubule)	0.024
SP1	Sp1 transcription factor	0.024
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.024
HOXD12	homeobox D12	0.024
MYH8	myosin, heavy chain 8, skeletal muscle, perinatal	0.023	Human
RBPMS	RNA binding protein with multiple splicing	0.023
ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)	0.023
LAD1	ladinin 1	0.022
CAV3	caveolin 3	0.022
PYGM	phosphorylase, glycogen, muscle	0.022
NPPB	natriuretic peptide B	0.022
FOXA2	forkhead box A2	0.021
TNNI3	troponin I type 3 (cardiac)	0.021
USP6	ubiquitin specific peptidase 6 (Tre-2 oncogene)	0.021
GRIP1	glutamate receptor interacting protein 1	0.021
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.020
CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.020
POU4F2	POU class 4 homeobox 2	0.020
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.020
PKD2L1	polycystic kidney disease 2-like 1	0.020
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.020	Mouse
ATXN1L	ataxin 1-like	0.019
IFITM3	interferon induced transmembrane protein 3 (1-8U)	0.018
ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	0.018
FGF3	fibroblast growth factor 3	0.018
JAG2	jagged 2	0.018
POU3F2	POU class 3 homeobox 2	0.018
TGFB1	transforming growth factor, beta 1	0.018
TAC1	tachykinin, precursor 1	0.018
SKIL	SKI-like oncogene	0.018
LHX5	LIM homeobox 5	0.018
MYOM1	myomesin 1, 185kDa	0.017
TAGLN	transgelin	0.017
TBX1	T-box 1	0.017
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.017
SFRP5	secreted frizzled-related protein 5	0.017	Human
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.017
NPAS1	neuronal PAS domain protein 1	0.017
SPTBN1	spectrin, beta, non-erythrocytic 1	0.017
FOXF2	forkhead box F2	0.017	Human
HTT	huntingtin	0.017
VAX2	ventral anterior homeobox 2	0.016
KRT5	keratin 5	0.016
TCAP	titin-cap (telethonin)	0.016
LMO1	LIM domain only 1 (rhombotin 1)	0.016
POU3F3	POU class 3 homeobox 3	0.016
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.016
GRB7	growth factor receptor-bound protein 7	0.016
ADAM9	ADAM metallopeptidase domain 9	0.016
RPL3L	ribosomal protein L3-like	0.015
MYH4	myosin, heavy chain 4, skeletal muscle	0.015	Human
EGLN3	egl nine homolog 3 (C. elegans)	0.015
MYF6	myogenic factor 6 (herculin)	0.015
SNW1	SNW domain containing 1	0.015
CDX2	caudal type homeobox 2	0.015
TTR	transthyretin	0.015
HDAC7	histone deacetylase 7	0.015
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	0.015
IFITM2	interferon induced transmembrane protein 2 (1-8D)	0.015
WNT2	wingless-type MMTV integration site family member 2	0.015
SYNPO2L	synaptopodin 2-like	0.015
CASQ1	calsequestrin 1 (fast-twitch, skeletal muscle)	0.014
SIX6	SIX homeobox 6	0.014
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.014
CNN2	calponin 2	0.014
NCOA6	nuclear receptor coactivator 6	0.014
FEV	FEV (ETS oncogene family)	0.014
SMAD7	SMAD family member 7	0.014	Mouse
SOX9	SRY (sex determining region Y)-box 9	0.014
LMO2	LIM domain only 2 (rhombotin-like 1)	0.013
ONECUT1	one cut homeobox 1	0.013
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.013
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.013
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.013	Mouse
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.013
NEUROG1	neurogenin 1	0.013	Human
NR5A2	nuclear receptor subfamily 5, group A, member 2	0.013
NCOA7	nuclear receptor coactivator 7	0.013
HOXD13	homeobox D13	0.012
SSX4	synovial sarcoma, X breakpoint 4	0.012
EFNB2	ephrin-B2	0.012
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.012
PITX2	paired-like homeodomain 2	0.012
T	T, brachyury homolog (mouse)	0.012
CFL1	cofilin 1 (non-muscle)	0.012
NRAP	nebulin-related anchoring protein	0.012
XIAP	X-linked inhibitor of apoptosis	0.012
FZD10	frizzled homolog 10 (Drosophila)	0.012
COL2A1	collagen, type II, alpha 1	0.011
TTN	titin	0.011
POU3F4	POU class 3 homeobox 4	0.011
LGALS3BP	lectin, galactoside-binding, soluble, 3 binding protein	0.011
NCOR2	nuclear receptor corepressor 2	0.011
CA3	carbonic anhydrase III, muscle specific	0.011
ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.011
ITGB1BP3	integrin beta 1 binding protein 3	0.011
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.011
DSG1	desmoglein 1	0.011
TFPI2	tissue factor pathway inhibitor 2	0.011
PYY	peptide YY	0.011
MED10	mediator complex subunit 10	0.011
MYOZ1	myozenin 1	0.011
CUX1	cut-like homeobox 1	0.011
GATA5	GATA binding protein 5	0.011
SCN4A	sodium channel, voltage-gated, type IV, alpha subunit	0.011
FOXF1	forkhead box F1	0.010
TULP1	tubby like protein 1	0.010
HSPB3	heat shock 27kDa protein 3	0.010
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.010
HRC	histidine rich calcium binding protein	0.010
SOX21	SRY (sex determining region Y)-box 21	0.010
PPARG	peroxisome proliferator-activated receptor gamma	0.010
CALCR	calcitonin receptor	0.010
IRX4	iroquois homeobox 4	0.010
MAB21L1	mab-21-like 1 (C. elegans)	0.010
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.010
TXNIP	thioredoxin interacting protein	0.010